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Euflexxa User Reviews & Ratings (Page 5)

Euflexxa has an average rating of 6.1 out of 10 from a total of 261 reviews on Drugs.com. 54% of reviewers reported a positive experience, while 35% reported a negative experience.

Reviews for Euflexxa

Commonly mentioned side effects
  • Anonymous
  • Taken for less than 1 month
  • October 8, 2019

For Osteoarthritis "Received my 2nd shot of Euflexxa following recovery from a broken tibial plateau that took way too long to heal and no major issues at all. Some tenderness after the injection, which is expected. Following instructions of taking it easy for a day or so is highly recommended. No side effects and immediate relief from osteoarthritis pain. Pain level decreased significantly after the 1st injection. Good alternative to invasive procedures and surgery. My experience may be different than yours."

9 / 10
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  • Che...
  • July 2, 2017

For Osteoarthritis "I have had this twice. The first lasted me almost 8 years before I needed 2nd injections, and now over 7 years and still pain-free. I'm happy with that. Injections work better than steroids and cortisone shots. Hardly any side effects."

10 / 10
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26 Report
  • Deb...
  • April 20, 2017

For Osteoarthritis "I have gone through 5 rounds of Euflexxa injections. The first couple, pain returned in about 3 months, then it went to 4 months, and now this last time it lasted 6 months. I still have pain when walking or standing, for I am bone on bone with both knees, but it helps bring my pain from a 10 down to a 4-5. I'm so glad for the Euflexxa, it is better than the cortisone with its side effects."

10 / 10
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  • Rob...
  • February 21, 2012

For Osteoarthritis "I'm going tomorrow for my third Euflexxa shot. I was told I am not bone to bone, but getting there. Severe arthritis in left knee. PKR is about 3-5 years out, so Dr's say (3 opinions). For a while, the NSAIDs worked, corticosteroid shots lasted about a month. Knee pain comes and goes and flares up and is worse each time. I am really encouraged that some have gotten years out of it. I am only 57 and like to work out every day, but my knee has held me back. The doctors have told me my knee is strong, I can't hurt it by working out. I just need to manage the pain and keep tabs on the swelling with ice. I felt 75% better after the first shot, the second hurt for a few days. Now it feels great. I hope this keeps getting better."

9 / 10
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  • Anonymous
  • March 21, 2009

For Osteoarthritis "After no improvement in pain from the cortisone shot, I started the series of three shots 6 weeks ago, and not only do I not show any improvement, my knee actually hurts more. Will have to go back to the doctor to see what is going on."

1 / 10
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53 Report

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  • Jaz...
  • October 3, 2018

For Osteoarthritis "I'm about to have my third year of Euflexxa shots. I'm 64 and am very active. I have OA and synovitis in my knees. I generally work out 5 days a week. These injections have given me complete relief for 7-9 months every year I have had them."

8 / 10
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  • Old...
  • Taken for less than 1 month
  • March 25, 2017

For Osteoarthritis "Amazing how quickly my knee pain disappeared. I have mild osteo and have had pain for the last 6 months. I just had my third shot 5 days ago. Some days I still do wake up with an ache in my knee and some nighttime ache. For the most part, it's been great. Hope it lasts. I have gone back to normal activities, i.e., tennis and elliptical at the gym."

9 / 10
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  • Dee...
  • October 15, 2016

For Osteoarthritis "I've had all three injections of Euflexxa, and my pain is no different. The pain in my knee is so severe I'm in tears some of the time, it's almost unbearable. I was hoping this medicine would help me postpone knee surgery, but it looks like that is now my only option. I had very high expectations for this treatment, I have several friends who had completely successful results. So very disappointed! The money spent was totally wasted."

1 / 10
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  • MsN...
  • September 30, 2015

For Osteoarthritis "I have had issues with both knees for approx 21 years. I had my left knee replaced in Aug of 2014. I don't want to experience that type of pain again. So today I received my 2nd injection of Euflexxa, and I'm limping a little more than normal. However, besides today, I can tell a slight difference. I'm hoping after my 3rd injection I can get back to walking and jogging. It is driving me nuts sitting still. I'm afraid to gain any weight back."

7 / 10
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  • Ric...
  • Taken for 1 to 2 years
  • January 4, 2019

For Osteoarthritis "I have had the series of 3 injections two different times. It has definitely helped to reduce the dull ache and the inflammation. It seems to help me for 4 to 5 months, and then the ache, pain, and inflammation return. It takes about a minute to receive the injection, and I have had no side effects at all. I get relief beginning after the first injection. Not a wonder drug, but I would recommend trying it."

8 / 10
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  • Gro...
  • April 25, 2019

For Osteoarthritis "This is my 2nd round of Euflexxa after the 1st round didn't work, it was decided that I should have arthroscopic surgery removing the torn part of my meniscus. Both times, the side effects were swelling, body aches, knees swelled, and hurt. So I'm done with Euflexxa. My opinion - not worth it!"

1 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • January 17, 2018

For Osteoarthritis "I took all three shots of Euflexxa about 10 weeks ago. The shots themselves were somewhat painful, however, tolerable. I have not experienced any relief from the pain of having had the shots done. I still have lots of swelling in my knee, and I'm limping even more."

2 / 10
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  • Jea...
  • February 22, 2018

For Osteoarthritis "First injection on Friday. No pain. Could walk ok. Next day, real pain to walk. Scale 1-10 (9). I iced down and took ibuprofen for pain. Most pain when trying to walk. Now it's been 6 days, and I've canceled my scheduled 2 injections. I wonder if I will get back to where I was before the shot? I'm 83, female, healthy (retired nurse). I live alone, and it's painful to get around. I read the success stories and wonder what went wrong for me. I also have a sore throat and joints ache, and I am more easily annoyed with my little dogs, I've noticed. I wasn't advised that any pain like this may happen. I believe it should have been."

1 / 10
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  • Ser...
  • February 8, 2017

For Osteoarthritis "Don't bother wasting your time with Euflexxa. I have been diagnosed with moderate osteoarthritis, and Euflexxa only made my condition worse. Now I am stuck with a sore back, I can hardly bend over, my limbs have no flexibility and are sore as heck. I don't get it. The treatment did not even come close to doing what it was described as. My doctor told me that the fluid only stays in your knee about two days, and then it is gone. It is not described that way on the Euflexxa website. It says it hardens into a gel, then forms a cushion between your bones. My experience is that this is NOT true. And how much am I paying for this??? Don't bother spending your money on Euflexxa. Your money is better spent on a partial or full knee replacement."

1 / 10
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  • Sur...
  • Taken for 1 to 2 years
  • October 27, 2016

For Osteoarthritis "I had injections in Jan 2015 in my knee where I previously tore the cartilage and had it debrided. Degeneration is bad, but I'm too young for knee replacement and really don't want it. I had several steroid shots prior, and they worked but for a very limited time. It did take some time for the Euflexxa to 'kick in.' I think it was about a month before I kind of stopped noticing my knee. It's now Oct 2016, and I'm just now noticing my knee again because I have degenerative problems in all my joints, and now it's the spine. The physical therapy is putting a strain on my knees (leg press, quad stretches), so now it's owie again. Until now, I've been able to cycle daily about 10 miles without too much problem unless we are talking steep hill."

8 / 10
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  • Xan...
  • May 2, 2016

For Osteoarthritis "I had this before. Good experience. Help lasted 5 years. The only problem I have is to get 3 injections that are very, very painful. Don't understand why they don't give a local anesthetic before injection. Then I was getting Silvist injection, I love that because I only get one injection. My insurance company refused to pay for it. They are! I hope that one day they have to do this! Sorry, just my opinion. Doctors need to take a stand against these evil, cold insurance companies who refuse to treat the patient right instead of making them suffer. They aren't doctors, they know nothing about what I need. The people who run insurance companies have ice running through their veins, they are not human."

10 / 10
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  • CJM...
  • February 3, 2017

For Osteoarthritis "I'm 44 and have osteoarthritis in both knees with Baker's cysts. Was told due to my age to try this as opposed to more drastic measures. First shot was about equivalent to getting a cortisone shot in my knees, pressure but bearable discomfort. A little sore the next day, week 2 and 3 about the same. Now I did just get a cortisone shot 2 weeks before starting the Euflexxa, but I figure now I am about 10% of the pain I was feeling prior. I hope it's the Euflexxa and not the cortisone masking it. Knees feel better every day and still pop here and there. But movement is dramatically better. 6 weeks since my first shot and I'm impressed and happy with my decision."

10 / 10
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  • Kat...
  • Taken for 2 to 5 years
  • April 1, 2021

For Osteoarthritis "My first experience with Euflexxa was almost 2 years ago. It gave me the much-needed pain relief and joint flexibility to continue with my passions of trail riding, backpacking in the mountains and canyons, downhill and cross-country skiing. It also allowed me to sit for hours while paddling my kayak without knee stiffness and pain. As it is not a permanent solution, I did recently receive my 2nd series of 3 injections as the stiffness and creaky knee was starting to return. Already I feel great and have a wonderful, oiled gate instead of a rusty, creaky one. Thank you to all who helped develop this active life-returning medication."

10 / 10
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  • Kim...
  • Taken for 1 to 6 months
  • May 10, 2018

For Osteoarthritis "3 injections. The 1st, not much change. The 2nd, a little better. The 3rd hurt and was painful, but after all was settled and done, my pain was alleviated a great deal. I'm a 49-year-old female with bone-to-bone arthritis and could barely walk. Now I'm good. I noticed, as time has passed, I'm a lot more active, and now I'm starting to go to the gym to lose weight and strengthen the muscles that support my knees. That way, when the Euflexxa wears off, I will be better able to manage my pain. I am one month down with my shots, and it's a 70/30, so I'm very happy with it. My doctor did state that since I am bone on bone, I had a 50/50 chance of it working or not. Well, grateful to say it works. Keep you posted in another few months! Great results so far."

8 / 10
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  • Den...
  • January 18, 2019

For Osteoarthritis "I am a 32-year-old female, in good physical health, weight, etc. I have severe osteoarthritis, and it is the worst case my orthopedic surgeon said he's ever seen in someone so young. I opted for the Euflexxa injections, 3 rounds, painful injections, supposed to feel a difference in 6 weeks. It has been 3 months, and my knees feel much worse than they did before the injections. I'm sure that has helped other people with knee issues, but for me it has done the opposite. My knees feel more weak than they ever have and are constantly painful."

1 / 10
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  • Gra...
  • Taken for less than 1 month
  • July 10, 2017

For Osteoarthritis "I am 76, a right-handed tennis player with left knee pain around the kneecap and toward the inside of the knee. I finished a series of 3 shots a couple of months ago and can report no improvement, in fact, the last few weeks pain is worse."

1 / 10
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  • Kar...
  • Taken for 5 to 10 years
  • March 31, 2024

For Osteoarthritis "I have been getting Euflexxa injections for 8 years now, twice a year. I have no pain in my knees, only stiffness after sitting for a while. It works wonders. My doctor is very gentle in giving the injections, he numbs the area beforehand, so I never feel anything. I had bone-on-bone and arthritis in both knees. A 77-year-young woman can still hike and ride a bike. It's working for me."

10 / 10
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  • Ccb...
  • Taken for 2 to 5 years
  • July 12, 2017

For Osteoarthritis "I am a 56-year-old woman with knee osteoarthritis (in both knees). I get Euflexxa injections every 6 months. They help me tremendously. By the time 5 months come around, I can tell I'll be needing them soon. If it can buy me time with getting these two bad knees replaced, I am thankful!"

9 / 10
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  • mmm...
  • Taken for less than 1 month
  • April 3, 2017

For Osteoarthritis "Left knee arthroscopic cleanup. Still bad. Steroid injection relief for a couple of months. Another injection with fluid removed and same. Can walk on even ground with little to no pain. Cannot go up stairs still, so try Euflexxa. After the first of three shots, I am in pain walking on even ground now. Worse. Back does not hurt, just knee on standing or walking. Don't know what the surgeon will do about this. This knee looked salvageable, so no replacement offered yet. Ironically, the other knee is totally bone on bone but has no pain. Was hoping to get through summer without big surgery."

1 / 10
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  • Joe...
  • March 21, 2017

For Osteoarthritis "I just received my last of 3 shots today. I'm in so much pain, and I have a very important computer install tomorrow at a big company, and I'm worried now. The first shot wasn't so bad, the second was about the same, but within days after the second shot, I started experiencing shooting pains all throughout my right knee. The pain progressed as the days went by. With the 3rd shot, as soon as the doctor removed the needle from my knee, I tried to bend my leg to roll down my pant leg, and it felt like someone drove a screw right through my knee. And the drive home was even worse. I had a similar experience with a cortisone shot a few years ago. I was told by another physician that it might have been an allergic response to the meds."

1 / 10
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