Euflexxa Side Effects
Generic name: sodium hyaluronate
Medically reviewed by Drugs.com. Last updated on Mar 9, 2023.
Note: This document contains side effect information about sodium hyaluronate. Some dosage forms listed on this page may not apply to the brand name Euflexxa.
Applies to sodium hyaluronate: injection gel/jelly, injection solution.
Serious side effects of Euflexxa
Along with its needed effects, sodium hyaluronate (the active ingredient contained in Euflexxa) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking sodium hyaluronate:
Less common
- Blue color or flushing or redness of skin
- cough
- difficulty in swallowing
- dizziness or feeling faint (severe)
- fever
- redness or pain at place of injection
- skin rash, hives, and/or itching
- stuffy nose
- swelling of eyelids, face, or lips
- tightness in chest, troubled breathing, and/or wheezing
Other side effects of Euflexxa
Some side effects of sodium hyaluronate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
- Diarrhea
- headache
- itching of the skin
- large, nonelevated blue or purplish patches in the skin
- loss of appetite
- nausea and/or vomiting
- stomach pain
- swelling of the knee
For Healthcare Professionals
Applies to sodium hyaluronate: injectable gel, intra-articular solution.
Local
Common (1% to 10%): Injection site pain/swelling/effusion/redness/warmth
Uncommon (0.1% to 1%):[Ref]
Hypersensitivity
Frequency not reported: Hayfever reaction on face and neck, reaction on forearms and knees
Postmarketing reports: Anaphylaxis/anaphylactoid reaction[Ref]
Other
Frequency not reported: Swelling of the face/eyelids/mouth/extremities, fever[Ref]
Gastrointestinal
Common (1% to 10%): Nausea, vomiting, abdominal pain, diarrhea, dyspepsia[Ref]
Cardiovascular
Frequency not reported: Transient hypotension[Ref]
Musculoskeletal
Very common (10% or more): Arthralgia (18%), arthropathy/arthrosis/arthritis (11%)
Common (1% to 10%): Back pain, leg discomfort, leg pain[Ref]
Immunologic
Common (1% to 10%): Influenza-like reaction[Ref]
Genitourinary
Common (1% to 10%): Urinary tract infection[Ref]
Respiratory
Common (1% to 10%): Upper respiratory tract infection, sinusitis, bronchitis, rhinitis[Ref]
Nervous system
Common (1% to 10%): Headache, dizziness[Ref]
Dermatologic
Frequency not reported: Rash, itching[Ref]
More about Euflexxa (sodium hyaluronate)
- Check interactions
- Compare alternatives
- Reviews (262)
- Dosage information
- During pregnancy
- Drug class: viscosupplementation agents
- En español
Patient resources
- Euflexxa injection drug information
- Euflexxa (Hyaluronate sodium Injection) (Advanced Reading)
- Euflexxa
Other brands
Durolane, Supartz, Hyalgan, Gelsyn-3, Supartz FX
Related treatment guides
References
1. Product Information. Hyalgan (sodium hyaluronate). Sanofi Winthrop Pharmaceuticals. PROD.
2. Product Information. Supartz (sodium hyaluronate). Smith and Nephew Wound Management Division. 2001.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.
