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Wegovy and Vomiting: What Users Say

Vomiting: mentioned by 51 users (10.4%)

Based on user experiences from 490 Wegovy reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

nausea 32.0%
constipation 14.3%
vomiting 10.4%
diarrhea 9.8%
tiredness 6.5%
headaches 6.1%
heartburn 6.1%
fatigue 5.3%
stomach pain 4.7%
upset stomach 4.5%

Reviews for Wegovy

Commonly mentioned side effects
  • Sks...
  • Taken for less than 1 month
  • May 25, 2023

For Weight Loss (Obesity/Overweight) "I never leave reviews and rarely have side effects from medication. However, after one injection on the lowest dose, I am so beyond sick. Two days after my injection, I got a migraine followed by extreme vomiting for 4 days, chills, nausea, and a trip to the ER. This medication made me so unbelievably sick, it is like I've been poisoned. I have missed 4 days of work and am so weak. Living on Pedialyte and numerous nausea medications. Please be so careful. I was so hopeful and had no idea this would happen to me."

1 / 10
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120 Report
  • 188...
  • Taken for 1 to 6 months
  • May 17, 2023

For Weight Loss (Obesity/Overweight) "Started Wegovy 3 months ago using the gradual phase-up method. From 0.25 mg dose for 4 weeks to 0.50 mg dose for 4 weeks, then 1.0 mg dose for 4 weeks. During the initial phase, I experienced mild nausea and some stomach irritation. With each increase, the symptoms got worse until finally, at the full 1.0 mg dose, I was so sick I thought I had stomach flu for 2 weeks continuously. The belching was horrible. The nausea caused uncontrollable vomiting, and I had frequent diarrhea. After 3 months, I lost 12 pounds and felt horrible every day. I've now reduced the dose to 0.5 mg but still suffer from nausea and stomach upset. I might cut back again, but I'm thinking I will quit. The way I feel all the time is horrible! I'm thinking I lost weight because of all the vomiting. Not recommended."

1 / 10
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38 Report
  • Jac...
  • Taken for less than 1 month
  • March 12, 2023

For Weight Loss (Obesity/Overweight) "Worst medication ever. On the lowest dose, I became deathly ill. I couldn't stop vomiting for a week. I could not walk because of extreme dizziness, and I could barely see from blurry vision. It also gave me the worst migraine of my life and suicidal thoughts and depression. I only lost weight because I could not eat at all and couldn't keep liquids down, so I was severely dehydrated. The side effects and long-term effects are so severe that the minor weight loss you would have from this medication is not worth it."

1 / 10
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137 Report

Frequently asked questions

  • Jan...
  • Taken for less than 1 month
  • January 9, 2023

For Weight Loss (Obesity/Overweight) "Took my first 0.25 mg Wegovy dose yesterday. I felt nauseous about an hour later, but within 2 hours, I started vomiting. For the next 16 hours, I dry heaved throughout the day and night. I couldn't even keep water down. It hasn’t been a full 24 hours yet since I took the shot and feel horrible, hoping that these side effects will stop soon. There is no way I’m taking another shot next week."

1 / 10
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42 Report
  • Jan...
  • Taken for less than 1 month
  • January 9, 2023

For Weight Loss (Obesity/Overweight) "Took my first 0.25 mg Wegovy dose yesterday. I felt nauseous about an hour later, but within 2 hours, I started vomiting. For the next 16 hours, I dry heaved throughout the day and night. I couldn't even keep water down. It hasn’t been a full 24 hours yet since I took the shot and feel horrible, hoping that these side effects will stop soon. There is no way I’m taking another shot next week."

1 / 10
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42 Report

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  • MM...
  • Taken for 1 to 6 months
  • December 22, 2022

For Weight Loss (Obesity/Overweight) "Wegovy has agonizing side effects. I had to quit after 2 months. Constant, uncontrollable vomiting, I vomited at work and while driving (which was horrific and dangerous). I essentially became bulimic and afraid to eat. I lost 20 pounds but put half of it back right away. Not worth the agony."

1 / 10
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53 Report
  • MM...
  • Taken for 1 to 6 months
  • December 22, 2022

For Weight Loss (Obesity/Overweight) "Wegovy has agonizing side effects. I had to quit after 2 months. Constant, uncontrollable vomiting, I vomited at work and while driving (which was horrific and dangerous). I essentially became bulimic and afraid to eat. I lost 20 pounds but put half of it back right away. Not worth the agony."

1 / 10
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53 Report

More FAQ

  • Har...
  • September 16, 2022

For Weight Loss (Obesity/Overweight) "Avoid this injection. I took my first dose a few weeks ago, and I have never been so sick. Constant vomiting after 4 hours, throwing up bile. Ended up in the hospital as I became dehydrated. A week later, still got on and off vomiting. The reflux is terrible and can't eat anything. It's better to be yourself than go through all this."

1 / 10
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40 Report
  • Gma...
  • Taken for less than 1 month
  • August 17, 2022

For Weight Loss (Obesity/Overweight) "I was given the max dose first, which was a huge mistake. It’s been 7 days of vomiting, weakness, headaches. Still can’t eat anything. This medication is very scary."

1 / 10
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23 Report
  • Bob...
  • Taken for less than 1 month
  • July 23, 2022

For Weight Loss (Obesity/Overweight) "Horrible experience after taking just the first dose. I’m going on my third week of being out of work. I have never been this sick. Violently vomiting one hour after my first and only dose. Heartburn, no energy, brain fog, couldn’t even speak coherently for the first 48 hours after taking. This stuff is like poison. Do not take it."

1 / 10
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27 Report
  • Sic...
  • Taken for less than 1 month
  • June 11, 2022

For Weight Loss (Obesity/Overweight) "Doctor skipped to 1.7, and I’ve been sick going on 4 days now. Severe nausea and vomiting, stomach pain, and headache, dehydration."

1 / 10
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14 Report
  • Mic...
  • March 6, 2022

For Weight Loss (Obesity/Overweight) "I started my first dose 1 day ago. I have been vomiting ever since. I can’t keep anything down. This is HORRIBLE…"

1 / 10
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4 Report
  • Anonymous
  • Taken for less than 1 month
  • January 22, 2022

For Weight Loss (Obesity/Overweight) "Worst experience of my life. After the second 0.25 dose, I was up all night vomiting and diarrhea. The next day, I had chest pain, shaking, brain fog, stomach pain, more diarrhea, and had to go to the ER. After they gave me Benadryl and morphine, I started to feel better. Still have burping, gas, and acid reflux terribly. WILL NEVER TRY THIS AGAIN! It is not worth it to me! Wish it would hurry up and get out of my system."

1 / 10
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221 Report
  • Fra...
  • Taken for less than 1 month
  • July 23, 2021

For Weight Loss (Obesity/Overweight) "This shot made me so sick for 3 days. I have never been so nauseous in my life. Threw up the 1st morning after taking it. Never use it again."

1 / 10
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25 Report
  • Ang...
  • Taken for 1 to 6 months
  • July 22, 2024

For Weight Loss (Obesity/Overweight) "I started on 0.25 Wegovy. The injections are painless and easy to administer. For the 4 weeks, I took this dose, I felt fine with little side effects. I lost 3 lbs. I then moved onto 0.5 dose. I took the dose on a Friday and woke in the middle of the night with terrible sudden reflux and vomiting. This happened for 3 nights. I took my next 0.5 dose the following Friday and the same happened, along with dizziness, constant nausea, and very low mood. I have decided not to take the last 2 injections I have left as I just feel so poorly."

2 / 10
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9 Report
  • Anonymous
  • Taken for 1 to 6 months
  • June 21, 2023

For Weight Loss (Obesity/Overweight) "I have lost 37 lbs in 3.5 months, but should be more due to the horrific side effects. Burping, belching, vomiting, diarrhea, chest pain, nausea, blurry vision, basically every side effect imaginable. I never had side effects from any medications before. I continued to increase the dose up to 1.7 mg and hope for the best with no success. I have three more weeks of misery, but due to the cost of $586, I refuse to trash this medication."

2 / 10
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7 Report
  • Hel...
  • March 17, 2022

For Weight Loss (Obesity/Overweight) "I can’t figure out how to live with this drug without feeling sick or vomiting. Zofran helps, as does not eating. Then I try to eat what seems like a small amount of food, and I’m sick. This sucks, but my last resort!"

2 / 10
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5 Report
  • Joe...
  • Taken for 1 to 6 months
  • May 30, 2023

For Weight Loss (Obesity/Overweight) "Side effects of nausea and vomiting. 0.5 mg doses are on serious back order, so went to 1 mg dose. No longer taking due to side effects."

3 / 10
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4 Report
  • Anonymous
  • Taken for 1 to 6 months
  • May 24, 2023

For Weight Loss (Obesity/Overweight) "Easy to administer, but during the first few weeks, had zero weight loss. Dose was increased. Woke in the middle of the night after the last dose with severe heartburn. Vomited every four hours for two days. Missed a day of work. Not able to keep anything down, including water. Put on anti-nausea medication. Have to sleep in a sitting position and take antacids and prescription meds to control heartburn enough to sleep. Cannot wait for the medication to get out of my system so I can function without vomiting or constant heartburn."

3 / 10
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27 Report
  • Dee...
  • Taken for 1 to 6 months
  • April 10, 2023

For Weight Loss (Obesity/Overweight) "I wish I did more research before starting this. I started on Saxenda and worked up to 3.0 mg, the max dose. I had a few bouts of severe diarrhea and vomiting. I lost a total of 15 pounds and then started getting ravenous. Then I got switched to Wegovy 2.0 mg and then moved up to 2.4 mg. I only had a couple of incidents of terrible nausea, usually when I ate greasy, heavy, or fried foods. But generally, I feel like crap every day. Once on the Wegovy, the weight literally fell off. Mostly because I just didn't think about eating anything, or my appetite would be satisfied with a very small portion of food. The biggest side effect is skin irritation; like a constant sunburn. Clothes touching my skin bother me. Or riding in a car and bouncing. It became intolerable. And chills make my skin ache. I easily surpassed my goal weight and now trying to decide if I want to quit it altogether or reduce the dosage and hope the skin irritation goes away."

3 / 10
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8 Report
  • Mic...
  • Taken for less than 1 month
  • November 11, 2022

For Weight Loss (Obesity/Overweight) "Horrible! Spent 24 hours in the ER with severe nausea and vomiting! Needless to say, I have 3 doses left if anyone needs!"

3 / 10
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8 Report
  • Car...
  • Taken for less than 1 month
  • July 25, 2022

For Weight Loss (Obesity/Overweight) "I am on my second week. First week (day after shot) I got severe nausea and dry heaving. I was so exhausted and zero energy. My depression got way worse. Second week the same. I don’t think I will continue, but I signed a contract, and I was told I can cancel at any time, but it looks like this is going to be a problem. This has been a wake-up call, and the nausea has taught me a lesson to never eat bad foods again and really focus on portion control. The side effects aren’t worth any weight loss in my opinion!"

3 / 10
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9 Report
  • Kar...
  • Taken for 1 to 6 months
  • February 2, 2022

For Weight Loss (Obesity/Overweight) "It works amazingly well, but the actual and physical cost was too much for me to continue. Been on it since August, and I've lost 40 pounds. That's really easy to do when you're starving due to constant nausea and vomiting. Though I'm terrified of gaining the weight back, as others described, I had to stop taking it as I was so sick every day and exhausted. I'm fighting it, but my appetite has already returned with a vengeance. That's not surprising, considering I've been malnourished for months."

3 / 10
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23 Report
  • All...
  • Taken for 1 to 6 months
  • March 15, 2023

For Weight Loss (Obesity/Overweight) "I took 4 shots of .25 Wegovy. The first shot had no side effects and no problems. The second shot was a little different. Mild upset stomach starting about 24 hours afterward with some stomach pain. This subsided within the third day. My appetite was suppressed, felt fuller for longer. In the third shot, I had no appetite with stomach pain that lasted two days, and also felt as if I were going to pass out. I drank orange juice and ate saltine crackers with peanut butter, which helped. The last .25 shot of Wegovy… I had lost 12 pounds by this shot. But within a day, I was projectile vomiting, upset stomach, extreme pain in my abdomen, chills, and dizziness. I was taken to the emergency room. I was diagnosed with colitis that had gone to sepsis. The doctor explained a side effect from Wegovy may cause gastrointestinal problems. Wegovy attacked my colon and in turn, sepsis formed. I will not continue this shot. So many side effects go with it. It does curve your appetite, but I would be very cautious."

4 / 10
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8 Report
  • Deb...
  • Taken for less than 1 month
  • December 12, 2024

For Weight Loss (Obesity/Overweight) "The first four days have been really rough. I’ve experienced nausea, vomiting, severe heartburn, and stomach pain. I really want this to work, so I’ll continue. The doctors have had to prescribe nausea and vomiting medicine. It helps. I’m taking Alka-Seltzer for the heartburn. I’m really hoping the side effects will stop."

5 / 10
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1 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.