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Wegovy and Nausea: What Users Say

Nausea: mentioned by 157 users (32.0%)

Based on user experiences from 490 Wegovy reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

nausea 32.0%
constipation 14.3%
vomiting 10.4%
diarrhea 9.8%
tiredness 6.5%
headaches 6.1%
heartburn 6.1%
fatigue 5.3%
stomach pain 4.7%
upset stomach 4.5%

Reviews for Wegovy

Commonly mentioned side effects
  • JAO...
  • Taken for 1 to 6 months
  • June 14, 2023

For Weight Loss (Obesity/Overweight) "I had been on this drug for 4 months. Typical escalation dose until month 4, I stayed on the 1 mg. The side effects were rough since increasing to 1 mg. So much nausea, worsened reflux, constipation, bloating, burping, and indigestion. I vomited once, but there were a few times I almost did. In the last few weeks, I noticed hair loss. Noticed skin tags that I have never had...like 3 grew since the med. Weird. Oh, and I had serious issues with certain smells. I had to change out the hand soaps in my house 5 times. If I smell rubbing alcohol, I am instantly nauseous. Just looking at the Wegovy box before injecting would make me dizzy and nauseous. So weird. Difficult to eat healthy on this med due to side effects, and only able to tolerate simple carbs, low-fat diet. Also hard to work out when feeling so nauseous...so didn't think it was contributing to my health. Has not really contributed to weight loss, and appetite is almost the same as before med."

1 / 10
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  • WmB...
  • Taken for less than 1 month
  • June 13, 2023

For Weight Loss (Obesity/Overweight) "Wegovy hasn't resulted in any weight loss. At times, I'm nauseous, full, and constipated regularly. Also, the injection device failed to work, no clicks or moving yellow bar. The product failed to go in and leaked all over, thereby causing me to get no shot/dosage."

1 / 10
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15 Report
  • Sks...
  • Taken for less than 1 month
  • May 25, 2023

For Weight Loss (Obesity/Overweight) "I never leave reviews and rarely have side effects from medication. However, after one injection on the lowest dose, I am so beyond sick. Two days after my injection, I got a migraine followed by extreme vomiting for 4 days, chills, nausea, and a trip to the ER. This medication made me so unbelievably sick, it is like I've been poisoned. I have missed 4 days of work and am so weak. Living on Pedialyte and numerous nausea medications. Please be so careful. I was so hopeful and had no idea this would happen to me."

1 / 10
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120 Report

Frequently asked questions

  • 188...
  • Taken for 1 to 6 months
  • May 17, 2023

For Weight Loss (Obesity/Overweight) "Started Wegovy 3 months ago using the gradual phase-up method. From 0.25 mg dose for 4 weeks to 0.50 mg dose for 4 weeks, then 1.0 mg dose for 4 weeks. During the initial phase, I experienced mild nausea and some stomach irritation. With each increase, the symptoms got worse until finally, at the full 1.0 mg dose, I was so sick I thought I had stomach flu for 2 weeks continuously. The belching was horrible. The nausea caused uncontrollable vomiting, and I had frequent diarrhea. After 3 months, I lost 12 pounds and felt horrible every day. I've now reduced the dose to 0.5 mg but still suffer from nausea and stomach upset. I might cut back again, but I'm thinking I will quit. The way I feel all the time is horrible! I'm thinking I lost weight because of all the vomiting. Not recommended."

1 / 10
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  • Tre...
  • Taken for less than 1 month
  • March 25, 2023

For Weight Loss (Obesity/Overweight) "I have been on this medication for one week. On the second day, I was very tired, on days 3-6, I was nauseous the whole time. Every time I ate something other than toast or crackers, I had major cramping, plus a mild headache all week. This was a horrible experience. The pain felt like a gallbladder attack. Never again."

1 / 10
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37 Report

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  • Jan...
  • Taken for less than 1 month
  • January 9, 2023

For Weight Loss (Obesity/Overweight) "Took my first 0.25 mg Wegovy dose yesterday. I felt nauseous about an hour later, but within 2 hours, I started vomiting. For the next 16 hours, I dry heaved throughout the day and night. I couldn't even keep water down. It hasn’t been a full 24 hours yet since I took the shot and feel horrible, hoping that these side effects will stop soon. There is no way I’m taking another shot next week."

1 / 10
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42 Report
  • Pen...
  • Taken for less than 1 month
  • October 31, 2022

For Weight Loss (Obesity/Overweight) "Don't use it! After having this, I was in bed for 6 days and had to go to the hospital to get hydration due to the risk to my kidneys. I felt as though this was a poison going through my body and almost immediately felt nauseous and could not keep anything down. Don't do it."

1 / 10
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More FAQ

  • No...
  • Taken for 1 to 6 months
  • September 18, 2022

For Weight Loss (Obesity/Overweight) "I took it for 6 months. Wanted to get to 2.4 because I kept thinking it would start working. No measurable weight loss or benefits. Lost 5 pounds. However, I have massive hair loss. Other minor symptoms like nausea. Would not recommend."

1 / 10
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33 Report
  • Gab...
  • Taken for 1 to 6 months
  • July 9, 2022

For Weight Loss (Obesity/Overweight) "Horrible, I had smelly sulfur burps and nausea at 1.7 mg. After the 2.4 mg limit, I became violently ill for two days. It was projectile from both ends. Very embarrassing. After that, just constant diarrhea for days. Throw it in the garbage."

1 / 10
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  • LAD...
  • Taken for 1 to 6 months
  • July 4, 2022

For Weight Loss (Obesity/Overweight) "I took Wegovy for a few months and did, in fact, lose some weight. The side effects are terrible, as so many others have noted here. One thing that they don’t tell you is that the drug slows down the stomach's ability to empty. This is why people feel full and experience reflux, nausea, etc. In my case, the drug not only slowed down my stomach's ability to empty, it permanently paralyzed my stomach muscles, a condition called gastroparesis. The only remedy was to have a neurotransmitter implanted in my stomach, which forces the muscles to move. Do NOT take or first this medication. You could end up like me with a lifetime medical issue. No weight loss is worth that."

1 / 10
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125 Report
  • Sca...
  • Taken for 1 to 6 months
  • June 20, 2022

For Weight Loss (Obesity/Overweight) "Wegovy definitely works if you can tolerate being nauseated all the time; it takes away cravings for everything. I had to force myself to eat. Fast forward 4 weeks on meds, I ended up getting the sickest I have ever been in my life! Thought I had the stomach flu for 4 days, but it just kept getting worse. Ended up in the ER with an inflamed liver, kidneys, severe kidney infection, urinary tract infection, and dehydrated. I would do anything to lose weight because I need a knee replacement and the doctor wants me to lose 30 pounds before he will operate. This scared me, BAD. I still don’t feel 100%. Anyway, who doesn’t want to lose weight, right? Well, after my experience, this is just not worth it. By the way, I have never had any issues with kidney, liver, etc. It was from this drug."

1 / 10
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39 Report
  • Sic...
  • Taken for less than 1 month
  • June 11, 2022

For Weight Loss (Obesity/Overweight) "Doctor skipped to 1.7, and I’ve been sick going on 4 days now. Severe nausea and vomiting, stomach pain, and headache, dehydration."

1 / 10
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14 Report
  • Mar...
  • Taken for 1 to 6 months
  • April 2, 2022

For Weight Loss (Obesity/Overweight) "No weight loss at all in 3 months. I’m at 1.5 dose now. I also have a sluggish thyroid, so not sure. Feel an upset stomach, acid reflux, and nausea. And very tired after the injection. Have lost about 3 lbs and gain it back by the next day. I eat low carb, and usually I’m not hungry. I have no idea why I'm not losing any weight."

1 / 10
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44 Report
  • fin...
  • Taken for 1 to 6 months
  • January 17, 2022

For Weight Loss (Obesity/Overweight) "Took it for 8 weeks, made it through the 2nd titrated dose and couldn't handle it anymore. Nausea, gas, bloat, constipation, diarrhea, and it was worse at night while lying down. Never improved, but actually got worse by week 8. Not sure how anyone makes it to the full dose. Also did not drop a single pound. There were days I only consumed 600 calories and still felt awful. I read another review very similar and agree that you absolutely cannot eat anything spicy. Bland food days were better but there are not enough antacids and constipation meds in the world to make me want to lose 20 pounds this badly. Took my last dose 10 days ago and am still dealing with residual GI upset. Hope physicians are more forthcoming about the side effects and do not tell patients they happen but subside in a couple of days - they do not."

1 / 10
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152 Report
  • Kma...
  • Taken for 1 to 6 months
  • January 10, 2022

For Weight Loss (Obesity/Overweight) "First of all, this does work. I lost over ten pounds in 6 weeks. The weight just fell off. Second of all, this was the worst experience I have ever had with a prescribed medication. Well, I started at the lowest dose and took that for 4 weeks before moving to the next dose, which I believe was 0.5 mg. The maintenance dose is 2.4 mg, I believe. How anyone makes it to the 2.4 mg is beyond me. I made it to the second dose of 0.5 mg before I threw in the towel. This stuff is WICKED. I spent 6 weeks of my life with an upset stomach, the absolute worst reflux and heartburn I have ever had, and constant nausea. I had to literally force myself to eat. Would not recommend. The side effects and the price are not worth it. Easy to lose weight when you are starving yourself and feel too sick to eat. Once I stopped, it took a few days to feel better and the weight came back lightening quick plus a few. Not worth the misery in my opinion."

1 / 10
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625 Report
  • Fra...
  • Taken for less than 1 month
  • July 23, 2021

For Weight Loss (Obesity/Overweight) "This shot made me so sick for 3 days. I have never been so nauseous in my life. Threw up the 1st morning after taking it. Never use it again."

1 / 10
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25 Report
  • Ang...
  • Taken for 1 to 6 months
  • July 22, 2024

For Weight Loss (Obesity/Overweight) "I started on 0.25 Wegovy. The injections are painless and easy to administer. For the 4 weeks, I took this dose, I felt fine with little side effects. I lost 3 lbs. I then moved onto 0.5 dose. I took the dose on a Friday and woke in the middle of the night with terrible sudden reflux and vomiting. This happened for 3 nights. I took my next 0.5 dose the following Friday and the same happened, along with dizziness, constant nausea, and very low mood. I have decided not to take the last 2 injections I have left as I just feel so poorly."

2 / 10
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9 Report
  • Anonymous
  • Taken for 1 to 6 months
  • June 21, 2023

For Weight Loss (Obesity/Overweight) "I have lost 37 lbs in 3.5 months, but should be more due to the horrific side effects. Burping, belching, vomiting, diarrhea, chest pain, nausea, blurry vision, basically every side effect imaginable. I never had side effects from any medications before. I continued to increase the dose up to 1.7 mg and hope for the best with no success. I have three more weeks of misery, but due to the cost of $586, I refuse to trash this medication."

2 / 10
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7 Report
  • JDF...
  • Taken for 1 to 6 months
  • May 13, 2023

For Weight Loss (Obesity/Overweight) "I started on the 0.25 mg, then increased to 0.5 mg and now on 1.7 mg. So far, I have not lost any weight and have been queasy almost the entire time. I have been using the relief band to help with the queasiness. I do not eat as much as I did before I started, plus I don’t drink alcohol hardly at all now. Besides that, I am not sure of the benefits yet. I will try it for another dose increase to see if it works. If it doesn’t, I am going to stop taking it."

2 / 10
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4 Report
  • Don...
  • Taken for 1 to 6 months
  • March 13, 2023

For Weight Loss (Obesity/Overweight) "I have had severe nausea and stomach pains, constipation, and back pain. Have had to stop taking it."

2 / 10
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4 Report
  • Sar...
  • Taken for less than 1 month
  • April 10, 2022

For Weight Loss (Obesity/Overweight) "Made me terribly sick. Took only 0.25 dosage one time, had terrible diarrhea, extreme exhaustion, and some nausea. Definitely not taking the second dose. Not worth the pain. Did not lose any weight either. It stops you from eating because it makes you feel so bad if you do. I also think this drug is meant for someone who doesn’t live an active lifestyle. I work out all the time, I eat healthy, and really just wanted to drop 15 lbs. This drug was very disappointing."

2 / 10
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18 Report
  • Hel...
  • Taken for 1 to 6 months
  • July 2, 2024

For Weight Loss (Obesity/Overweight) "Started with 0.25mg, very easy, full instructions, separate pens for each dose increment, so foolproof. The nausea started within a couple of hours of the first injection, over the first month the nausea was pretty constant all day but eased off after around 5 days so 2 days with minimum nausea, however within 1 hour of 0.5mg dose nausea was worse and no let up, was actually sick on 1 day and felt like I would be sick in the second week. After 2 weeks on 0.5mg decided I could not continue to feel unwell ongoing. Weight loss was minimal, less than 1lb per week with 'careful' eating choices although not fully dieting but think you have to be very determined to tolerate the nausea."

3 / 10
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6 Report
  • Joe...
  • Taken for 1 to 6 months
  • May 30, 2023

For Weight Loss (Obesity/Overweight) "Side effects of nausea and vomiting. 0.5 mg doses are on serious back order, so went to 1 mg dose. No longer taking due to side effects."

3 / 10
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4 Report
  • Anonymous
  • Taken for 1 to 6 months
  • May 24, 2023

For Weight Loss (Obesity/Overweight) "Easy to administer, but during the first few weeks, had zero weight loss. Dose was increased. Woke in the middle of the night after the last dose with severe heartburn. Vomited every four hours for two days. Missed a day of work. Not able to keep anything down, including water. Put on anti-nausea medication. Have to sleep in a sitting position and take antacids and prescription meds to control heartburn enough to sleep. Cannot wait for the medication to get out of my system so I can function without vomiting or constant heartburn."

3 / 10
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27 Report
  • Lyn...
  • Taken for less than 1 month
  • May 10, 2023

For Weight Loss (Obesity/Overweight) "I haven't noticed much weight loss with this medication. I have experienced extreme nausea to almost vomiting. I have also suffered from daily headaches from this medication. I have also noticed my blood pressure fluctuates higher than my normal high. I am only on the 1.0 mg dosage right now, and my doctor will increase it next week. I do have to say the pens are very easy to use, and the needle injections don't hurt."

3 / 10
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3 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.