Wegovy and Upset Stomach: What Users Say

• 188...
• Taken for 1 to 6 months
• May 17, 2023

For Weight Loss (Obesity/Overweight) "Started Wegovy 3 months ago using the gradual phase-up method. From 0.25 mg dose for 4 weeks to 0.50 mg dose for 4 weeks, then 1.0 mg dose for 4 weeks. During the initial phase, I experienced mild nausea and some stomach irritation. With each increase, the symptoms got worse until finally, at the full 1.0 mg dose, I was so sick I thought I had stomach flu for 2 weeks continuously. The belching was horrible. The nausea caused uncontrollable vomiting, and I had frequent diarrhea. After 3 months, I lost 12 pounds and felt horrible every day. I've now reduced the dose to 0.5 mg but still suffer from nausea and stomach upset. I might cut back again, but I'm thinking I will quit. The way I feel all the time is horrible! I'm thinking I lost weight because of all the vomiting. Not recommended."

• Mar...
• Taken for 1 to 6 months
• April 2, 2022

For Weight Loss (Obesity/Overweight) "No weight loss at all in 3 months. I’m at 1.5 dose now. I also have a sluggish thyroid, so not sure. Feel an upset stomach, acid reflux, and nausea. And very tired after the injection. Have lost about 3 lbs and gain it back by the next day. I eat low carb, and usually I’m not hungry. I have no idea why I'm not losing any weight."

• Kma...
• Taken for 1 to 6 months
• January 10, 2022

For Weight Loss (Obesity/Overweight) "First of all, this does work. I lost over ten pounds in 6 weeks. The weight just fell off. Second of all, this was the worst experience I have ever had with a prescribed medication. Well, I started at the lowest dose and took that for 4 weeks before moving to the next dose, which I believe was 0.5 mg. The maintenance dose is 2.4 mg, I believe. How anyone makes it to the 2.4 mg is beyond me. I made it to the second dose of 0.5 mg before I threw in the towel. This stuff is WICKED. I spent 6 weeks of my life with an upset stomach, the absolute worst reflux and heartburn I have ever had, and constant nausea. I had to literally force myself to eat. Would not recommend. The side effects and the price are not worth it. Easy to lose weight when you are starving yourself and feel too sick to eat. Once I stopped, it took a few days to feel better and the weight came back lightening quick plus a few. Not worth the misery in my opinion."

• All...
• Taken for 1 to 6 months
• March 15, 2023

For Weight Loss (Obesity/Overweight) "I took 4 shots of .25 Wegovy. The first shot had no side effects and no problems. The second shot was a little different. Mild upset stomach starting about 24 hours afterward with some stomach pain. This subsided within the third day. My appetite was suppressed, felt fuller for longer. In the third shot, I had no appetite with stomach pain that lasted two days, and also felt as if I were going to pass out. I drank orange juice and ate saltine crackers with peanut butter, which helped. The last .25 shot of Wegovy… I had lost 12 pounds by this shot. But within a day, I was projectile vomiting, upset stomach, extreme pain in my abdomen, chills, and dizziness. I was taken to the emergency room. I was diagnosed with colitis that had gone to sepsis. The doctor explained a side effect from Wegovy may cause gastrointestinal problems. Wegovy attacked my colon and in turn, sepsis formed. I will not continue this shot. So many side effects go with it. It does curve your appetite, but I would be very cautious."

• Nik...
• Taken for 1 to 6 months
• May 7, 2023

For Weight Loss (Obesity/Overweight) "Checking in about my experience on Wegovy thus far. Tomorrow, Monday, May 8th, 2023, will be my second box of Wegovy 0.25 mg. So my 5th injection. I’ve lost 6 pounds since I first started. My biggest issue is diarrhea and nausea. I get occasional stomach cramping. Otherwise, I too have noticed that drinking more water seems to help. Lots of saltine crackers for me. The first week, I was scared to eat. I felt like I had the flu. It wasn’t a good experience for me. Then, gradually it let up, and by that first Friday, I felt like myself again, but still ate with caution. I have no taste! It’s odd. I know I’m eating, but it’s like I’ve lost my sense of taste. I will update after these 2 boxes are complete and hopefully will have a total weight loss that’s up to date. I don’t own a scale, lol."

• Tom...
• Taken for 6 months to 1 year
• April 13, 2023

For Weight Loss (Obesity/Overweight) "Started Wegovy in March 2022 with a goal of losing 50-75 pounds. I ended up losing a total of 85 pounds in about 11 months. I felt great upon taking the Wegovy. Only had mild headaches and mild stomach discomfort. I was not tired, I actually felt energized. However, by December, the nausea had reared its ugly head. I took Zofran, and it helped. I was able to stick it out with the nausea until February, at which time I stopped taking it. I could no longer live with the nausea. Since I stopped taking it, I have continued to suffer nausea, vomiting, and stomach pain. My doctor and I are still trying to find the source of this continuing issue. I love the weight loss, and I love Wegovy!"

• Ste...
• Taken for 1 to 6 months
• March 14, 2025

For Weight Loss (Obesity/Overweight) "Been taking Wegovy for 2 months now. First month, very little side effects & lost 14 lbs. Second month, moved up to the 0.5 dose. Stomach issues started, mainly rumbling noises with diarrhea/constipation. Has gone on for weeks now (not days), so have referred myself to my GP."

• Gre...
• Taken for 1 to 6 months
• January 6, 2025

For Weight Loss (Obesity/Overweight) "I've been injecting Wegovy for the past three months on a weekly basis. I am at the 1 mg dosage. I have been having brief dizzy episodes. These could be related to my Lisinopril dosage. I have had stomach upsets and fatigue, but no trouble with the injecting. I have lost 25 pounds since starting - 220 - 195 lbs. I have been able to tolerate the side effects."

• deb...
• Taken for 1 to 6 months
• October 7, 2024

For Weight Loss (Obesity/Overweight) "Chronic abdominal cramping, lightheadedness, occasional stomach pain, and loss of taste. The 0.5 shot easy to use once a week, gradual increase. Been taking for less than 2 months and lost 12.5 lbs."

• Jer...
• Taken for less than 1 month
• March 28, 2023

For Weight Loss (Obesity/Overweight) "I am in my fourth week of Wegovy (at .25 mg). I am a female in my early 50s, 5'8", and have struggled to lose weight and need to lose 100 lbs. So far, I have not experienced any significant side effects but have seen a little more fatigue than normal, and after injection during the day only a slightly upset stomach. I have lost 13 pounds. I work out five times a week and watch/track my diet. I find that drinking a lot of water and watching what I am eating (staying at about 1,500 to 1,800 calories) with high protein helps. Because you feel full, it is a challenge to reach calories - smaller meals throughout the day help. Also, find a support group of others on the medication to get tips and ideas. I found this to be very helpful."

• Weg...
• Taken for 1 to 6 months
• March 20, 2022

For Weight Loss (Obesity/Overweight) "Started with Ozempic .25 ml dosage and have ramped up to 1 ml dosage over 3 months. They started me on Ozempic due to the shortage of Wegovy back then. Today I start Wegovy at 1.7 ml and I'm not even on the maximum dosage yet. I just got back from the doctor and I have lost 9.5 percent of my body weight, my blood pressure is way down, and my A1C level has gone from 7 to 5.8 in that time! One drawback is that I have had significant stomach issues with this drug that come and go. Forget about eating anything spicy or heavy at night, and it does curb your appetite, big time. I probably eat half as much as I used to. Overall, it is the best thing that has happened to me."

• Ano...
• Taken for 1 to 6 months
• May 7, 2025

For Weight Loss (Obesity/Overweight) "I lost 25 lbs on a 0.25 Wegovy dose between February 25th and May 7th (about 10 weeks). I went from 178 lbs to 153 lbs. I am a male, 5'6''. I was already exercising for 45-50 minutes a day for 6 days a week, but I could not lose the weight. Wegovy helped me control my appetite mentally, resulting in fewer calorie intake, and boom, the weight started to come off. I also have fatty liver disease and have recently seen some studies showing promising results with this drug. I sometimes have mild bloating and stomach cramps, but not extreme."

• Ter...
• Taken for 6 months to 1 year
• January 12, 2025

For Cardiovascular Risk Reduction "My experience with Wegovy. - Experienced upset stomach and nausea initially, but these symptoms were manageable. - Lost 32 pounds in six months, with reduced appetite as a significant benefit. - Knee issues have limited exercise, but weight loss has contributed to lower blood pressure. - Monthly cost is around $200, with insurance coverage easing the financial burden. - Wegovy's injection is easy to use and comes with excellent support and reminders."

• Chr...
• Taken for 1 to 6 months
• March 28, 2022

For Weight Loss (Obesity/Overweight) "I started on Wegovy in December 2021. In the beginning, it made me sick to my stomach. I had the belching and very little appetite. When I got to 0.50 mg, oh my God! I could hardly eat anything for a couple of days. I was scared to go to the next level, but I did. When I was on the 1 mg dose, I didn't have any issues. Once I got to 1.7 mg, it wasn't bad either- a little belching, headaches for a couple of days, upset stomach, and constipation kicked in. Getting ready to start the maintenance level of 2.4 mg, and let's pray I tolerate it well. So far, I have only lost about 27 lbs, trying to lose about 17 more to get to my ideal weight. This is the best medicine that has helped me lose and, prayerfully, keep it off. I have learned how to eat small meals and make better choices in foods."

• Hap...
• Taken for 1 to 6 months
• August 4, 2024

For Weight Loss (Obesity/Overweight) "I started June 11, 2024, at 194 lbs. At 1 month, lost 10 lbs. At 7 weeks, am down 17 lbs. I've tried to lose this weight for over a year now. I am a 59-year-old female at 5’4”. The first shot had a little upset stomach for a day or two, but not bad. I would highly recommend this drug. First time I have had hope to reach my goal weight."

• Tim...
• Taken for less than 1 month
• June 5, 2024

For Weight Loss (Obesity/Overweight) "Tuesday was the second shot. So far, no headaches, just upset stomach now and then. I really like that it takes all hunger away. Now I just focus on eating healthy and much less. I'm a 60-year-old man, started at 293 lbs. Tuesday, before the shot, I weighed 283. I feel better when I drink water, which I drink at least 10 bottles a day. Eat more fruit and veggies."

• Kev...
• Taken for less than 1 month
• December 2, 2023

For Weight Loss (Obesity/Overweight) "It sure works. Even at the lower initial doses, it completely CURBS your appetite, and you are no longer hungry. It’s an interesting phenomenon. I’m going to have to plan means better and so forth. So far, side effects have been mild stomach upset and fatigue, but nothing substantially more…"

• jwi...
• Taken for 1 to 6 months
• June 15, 2023

For Weight Loss (Obesity/Overweight) "I have been on Wegovy now for 4 months and have lost 26 pounds. I am currently on the 1.7 mg, and I have had no nasty side effects. I have had more heartburn than I used to, and occasional stomach upset, but nothing that would make me stop taking the meds. It has been a slow loss, but it is a loss, and I am very happy. I would love to lose 75-100 pounds, and hopefully this will continue to work, and I will meet my goal. My start weight was 250 lbs, I am now at 224 lbs. My glucose levels have decreased, and my A1C has also lowered. I have not been adding exercise, I feel if I started walking, the weight would come off faster. My overall experience has been very satisfactory."

• Jah...
• Taken for less than 1 month
• April 16, 2023

For Weight Loss (Obesity/Overweight) "So far, so good! Only on the 3rd day on it, but I'm loving it. On .25 mg dose to start. I'm female, 5'4", 215 lbs, and I'm looking to drop about 40 lbs with it. Very mild stomach discomfort here and there, but it's barely noticeable the vast majority of the time. When I first injected, I felt that my heartbeat got quicker for a little bit, but it subsided in an hour or two. I don't crave junk food anymore. I feel like I'm always full, and I have an increased desire for whole foods. I'm not going to increase my dose until I feel the beneficial effects subsiding, I'm taking it very slow to avoid side effects. Will check back in after a month or two, I'm very optimistic!"

• Dog...
• Taken for less than 1 month
• March 23, 2023

For Weight Loss (Obesity/Overweight) "I am in my first month. Had second injection last Saturday. I lost 5 pounds in the first week. Definitely curbs your appetite! I have had a small amount of stomach discomfort and gas. Hoping to continue to lose weight. I will update as time passes."

• In ...
• Taken for 1 to 6 months
• June 7, 2022

For Weight Loss (Obesity/Overweight) "6-7-2022: I am about to start my eighth week on Wegovy: first four weeks at 0.25 mg, second four weeks at 0.5 mg, and starting 1.0 mg this week if I can get the medicine. My pharmacy is having difficulty getting it. The first week was difficult. I started on a Thursday evening and had diarrhea for two days straight and accompanying upset stomach. I took Friday off from work and was sick on Saturday. On Sunday, I felt better but very tired and stayed in bed all day. I was feeling better by Monday and Tuesday. Since then, few side effects. I lost 5 lbs. the first month and 7 the second, averaging my doctor's goal of 6 lbs./week. I'm so glad to be moving in the right direction. I'm 5'2" and weighed 260 at my highest. I lost 30 pounds a couple of years before COVID hit and had kept it off (a major triumph) but had gained back 10 of those pounds before starting Wegovy."

• Jen...
• Taken for 1 to 6 months
• February 16, 2022

For Weight Loss (Obesity/Overweight) "I am on my first week of the 2.4 dose (so I am just starting month 5). My weight loss seems a bit slower than others (story of my life), BUT I am still losing! I’ve lost 26 pounds in 5 months with making few modifications to my diet. I eat similarly to how I did before, but my portions are much smaller. I have experienced some side effects, but everyone’s experience is different. I can usually combat the upset stomach and gas with Gas-X and Pepto. I have experienced constipation, but that’s honestly something I’ve battled all of my adult life. Miralax in my morning tea or coffee certainly helps with that. Bottom line for me is this… the occasional side effects are 100% worth the results I’m seeing!"