Wegovy and Tiredness: What Users Say

• Tre...
• Taken for less than 1 month
• March 25, 2023

For Weight Loss (Obesity/Overweight) "I have been on this medication for one week. On the second day, I was very tired, on days 3-6, I was nauseous the whole time. Every time I ate something other than toast or crackers, I had major cramping, plus a mild headache all week. This was a horrible experience. The pain felt like a gallbladder attack. Never again."

• Bob...
• Taken for less than 1 month
• July 23, 2022

For Weight Loss (Obesity/Overweight) "Horrible experience after taking just the first dose. I’m going on my third week of being out of work. I have never been this sick. Violently vomiting one hour after my first and only dose. Heartburn, no energy, brain fog, couldn’t even speak coherently for the first 48 hours after taking. This stuff is like poison. Do not take it."

• Mar...
• Taken for 1 to 6 months
• April 2, 2022

For Weight Loss (Obesity/Overweight) "No weight loss at all in 3 months. I’m at 1.5 dose now. I also have a sluggish thyroid, so not sure. Feel an upset stomach, acid reflux, and nausea. And very tired after the injection. Have lost about 3 lbs and gain it back by the next day. I eat low carb, and usually I’m not hungry. I have no idea why I'm not losing any weight."

• Jji...
• April 2, 2023

For Weight Loss (Obesity/Overweight) "Awful. I felt tired and like I had morning sickness the whole time. Was on one month of .25 mg and two months on .5 mg. It never got better. I was constipated and on the verge of throwing up constantly. Also started post-menopausal bleeding despite being on HRT. All of this, and I only lost a whopping 9 pounds despite barely being able to eat even cereal. Your diet turns to garbage because you just stick to stuff that won’t make you feel more nauseous. You will not learn how to eat properly; just how not to eat foods that make you throw up. I just switched to phentermine, and I’ve already lost two pounds in 5 days. My energy is back. Zero side effects and less than $15/month. Read the long-term reviews, people. Unless you are going to stay on this for life, which I would never do seeing how it messed with my hormones, you will 100% gain it all back and then some."

• Car...
• Taken for less than 1 month
• July 25, 2022

For Weight Loss (Obesity/Overweight) "I am on my second week. First week (day after shot) I got severe nausea and dry heaving. I was so exhausted and zero energy. My depression got way worse. Second week the same. I don’t think I will continue, but I signed a contract, and I was told I can cancel at any time, but it looks like this is going to be a problem. This has been a wake-up call, and the nausea has taught me a lesson to never eat bad foods again and really focus on portion control. The side effects aren’t worth any weight loss in my opinion!"

• Anonymous
• Taken for 1 to 6 months
• May 22, 2023

For Weight Loss (Obesity/Overweight) "I am experiencing extreme insomnia and tiredness. I am not sure if I will continue taking it."

• Car...
• Taken for 1 to 6 months
• April 24, 2023

For Weight Loss (Obesity/Overweight) "I am on week 4 of Wegovy, the first 2 doses were 0.25 mg. The last 2 were 0.5 mg. I've had stomach pains and nausea to the point I'm in tears, it aches so much. My weight is going from 221 lbs to 215 lbs, I'm 5'9". I hardly eat for fear of worsening stomach issues. While my pharmacist says the side effects should go away by now, they haven't. I also have no energy, want to sleep, and have a hard time getting my blood sugar above 98, that's after a healthy meal with protein and a vegetable. Not sure this is worth it."

• Cad...
• Taken for 1 to 6 months
• April 7, 2025

For Weight Loss (Obesity/Overweight) "Mixed review: I took Wegovy for 5 months, hoping to ultimately lose 15-20 pounds. I didn’t start losing weight until I started the 1.7 mg dosage (third month), and at that dosage, I was exceedingly tired and achy. I lost 10 pounds in 4 months but stopped taking it because of these side effects. Four months later, without Wegovy, I’m still down 5 pounds. My insurance partially covered this with a significant copay because I also have cardiovascular risks. I’d recommend only if you don’t experience the same side effects."

• Cal...
• Taken for less than 1 month
• May 12, 2023

For Weight Loss (Obesity/Overweight) "My experience with Wegovy has been a rollercoaster. In the first week, the 0.25 mg dose was great. In the second week, I started feeling the side effects of nausea, burping, gas, diarrhea, and bloating. I noticed that I did eat more. Make sure your portions are small and stick to fruit and vegetables. Soups and not greasy processed foods. You may feel sick and will take longer to digest. I am currently reconsidering if I should continue. I am not sure if I want to experience the side effects at a higher dose. I feel terrible all the time and have a headache. I feel exhausted all the time."

• Mad...
• Taken for 1 to 6 months
• May 9, 2023

For Weight Loss (Obesity/Overweight) "Lots of annoying side effects without losing any weight the first 4 months. Didn't lose any weight until I started exercising with a diet of less than 1,000 calories a day. Worse side effects: significant sleepiness, especially after eating, severe indigestion, and GERD. Injections easy to do and usually no associated pain. Am finishing my last dose of 1.7 mg this week, and after all these months, I have finally lost 9 lbs, all in the last month, once I started bike riding and water aerobics. But you have to decide if the side effects are worth it. I am retired, so I have been taking a 2-hour nap almost daily since I feel extremely tired a few hours after getting up in the morning. I have felt generally unwell the whole time I have taken it, although I am able to continue my life as usual. I can't wait to get off it, although they say it may be a lifelong medication. I hope that my body will eventually get used to it."

• Sym...
• Taken for less than 1 month
• April 12, 2023

For Weight Loss (Obesity/Overweight) "I took my first dose, and that night and the next day, I experienced unusual tiredness and weakness. It also felt like I had a fever and/or the onset of the flu."

• Lee...
• Taken for 1 to 6 months
• August 25, 2022

For Weight Loss (Obesity/Overweight) "I have been on Wegovy for 10 weeks and haven't lost any weight so far. My appetite isn't suppressed like it's supposed to be. I'm not sick or nauseous, there is no effect on me other than being tired. I'm wondering if it will start working any time soon. I'm on the 2.4 mcg strength, which is the highest."

• blh...
• Taken for less than 1 month
• May 31, 2024

For Weight Loss (Obesity/Overweight) "First dose 0.25mg, had slight stomach pain/discomfort. Later that same night, my appetite disappeared. Just seeing a fast-food commercial on TV made me feel nauseous. I thought if that's the worst of the side effects that affect me, then I'll be very happy with that. By the next day, stomach pain and nausea increased. By 4:00 am, BAM! Diarrhea, severe stomach pain, projectile vomiting, headache, chest pain, severe itching mainly on the palms of my hands and arms. I truly thought 'this must be what it feels like to be poisoned!' I was scared. It is now the next day and I feel fine. A little tired from lack of sleep from feeling so sick. I think I will do my second dose next week...but I'm quite nervous of a repeat of feeling like I was dying from the stomach pains and vomiting. Will I continue with this drug?...jury is still out! On the positive side, I've already lost 5 pounds; but of course, I can't & don't want to eat, too much nausea and vomiting."

• Mer...
• Taken for 1 to 6 months
• December 29, 2021

For Weight Loss (Obesity/Overweight) "I have been on it for 2 months. I am at .5 right now and have lost 18 pounds. That’s great, but I am exhausted lately and very constipated. Going to my primary on Friday for blood work. If the side effects continue, I will have to stop."

• Sid...
• Taken for 1 to 6 months
• September 5, 2024

For Cardiovascular Risk Reduction "I've only been taking this for a month. I am extremely tired the day after taking the shot for a full 24 hours. Not taking it anymore, but I did lose 7 pounds."

• yir...
• Taken for less than 1 month
• May 2, 2023

For Weight Loss (Obesity/Overweight) "I started Wegovy .25 mg on March 5th. On day 1, I felt a little nausea and a little tired. Felt fine the rest of the week, appetite suppressed after a day or so. Continued to follow a healthy diet, exercised at least 5 days a week, and meal portions became smaller. I did not experience any other side effects aside from a little heartburn at night after the 2nd dose. By the 3rd dose, I started feeling somewhat constipated and noticed my watch was notifying me more frequently than usual that my heart rate was over 100 throughout the day and night. I take blood pressure medication, so I decided to call my doctor. She does want me to get blood work done and will be checking my thyroid. Also recommended I stop taking the med. I am a bit worried as I already feel the cravings are coming back. After I complete blood work, I will provide additional feedback regarding recommendations from my PCP. I have lost about 14 lbs., so it does work. I would give it a shot, everyone reacts differently."

• Fir...
• Taken for less than 1 month
• May 1, 2023

For Weight Loss (Obesity/Overweight) "I started Wegovy the first week of April 2023. I was hesitant at first because of all the negative reviews, but I finally did it. The first day was good. I injected it in my thigh, which was fine. After a few minutes, I felt a burning sensation in the back of my leg, then it went away. I've done my 3rd injection this week, and the only side effects are being kind of tired. Other than that, I'm fine. My hair has always fallen out because it's hereditary, so the hair fall I have is not due to that. I have way less cravings for junk food and don't feel as hungry. The first week, I lost 7 lbs. Gained 4 back due to eating late at night after work. I usually stop eating at 6 pm. Make sure if you take this to drink lots of water because you will feel thirsty. Other than that, I've overall had a great experience with this. I'm glad my cravings are no longer. I have a long way to go since I'm wanting to lose at least 80 lbs. I have an infant now, so I'm not as active. Good luck to those who want to try."

• Shy...
• Taken for 1 to 6 months
• November 1, 2021

For Weight Loss (Obesity/Overweight) "Been on Wegovy for 7 weeks. Lost 14 pounds. 2nd week into 0.50 mg. It’s a little rough on my stomach. Taking prescription for nausea which happens the day of the injection. Feel tired and occasionally get severe abdominal pains. I can’t eat much and have to really watch the types of food. No greasy foods or spicy or heavy. The intestinal pains were very severe after eating wrong foods. I’m happy with the weight loss but the side effects are rough."

• My ...
• Taken for 1 to 6 months
• December 26, 2024

For Weight Loss (Obesity/Overweight) "I just started my 2nd injection of Wegovy. I had no side effects with the first injection at all but lost 2 lbs. On my 2nd, I feel a little tired, but no symptoms so far. I can tell that I need to drink more water, and it seems that I can no longer finish a plate of food. I’m glad my doctor recommended I try this. It really does work!"

• Mar...
• July 7, 2024

For Weight Loss (Obesity/Overweight) "I was 182 lbs and have been on Wegovy for about 4 months. I am now 168 lbs. I was quite nauseous at the start and found that by eating a mouthful of plain bread helped with the nausea. I have also been quite tired and although not constipated, my poops are firmer."

• Arc...
• Taken for less than 1 month
• June 19, 2023

For Weight Loss (Obesity/Overweight) "Began Wegovy three weeks ago, have lost 11 pounds so far. Ready to move up to the 0.5 mg dose. Side effects have been minimal, some tiredness and a bit of constipation, but nothing awful. The key is to listen to your body. If you feel full, then stop eating. That's Wegovy doing its job. Don't ignore it. Good luck to all."

• Car...
• Taken for 1 to 6 months
• June 4, 2023

For Weight Loss (Obesity/Overweight) "In February of '23, I learned that I had a hiatal hernia where 2/3rds of my stomach was above my diaphragm. The doctor said she could operate, but it wouldn't stay fixed because of my body mass. So my primary care PA suggested Wegovy. I agreed to try it. The first 3-4 days of my first week were rather rough. I had horrible gas, diarrhea, and nausea. I could eat berries and yogurt, but not much else. Over the first 2 months, I lost 12 pounds. Then I plateaued. There also was a mix-up with getting my next 4 doses on time, so I went a couple of weeks with no doses. Most recently, we upped my dose, and now at 1.7 mg, I don't have many stomach problems, but I feel tired all the time. I get up and do a few things, and then I take a nap. And repeat. I had one time when I started to feel dizzy and faint because my blood sugar was low, but a sweet drink and a burrito helped with that. I am still slowly losing weight, which makes me happy! I've lost a total of 18 pounds in about 4 months."

• Sco...
• Taken for less than 1 month
• May 9, 2023

For Weight Loss (Obesity/Overweight) "Started with the 0.25 mg dose and had very little side effects. A slight tiredness was felt but noticed immediately the reduced level of my appetite and hunger needs. I felt full sooner with smaller portions of food and had no cravings to nibble on stuff at night, which was the norm for me. Make sure to eat well with a basic caloric intake needed for your height and weight, drink plenty of fluids, and get decent sleep daily. This, along with a normal gym schedule, works wonders! I have been on the medication for 5 days now and lost (I assume mostly water weight) 5 lbs in this short time period. I stay active, which also helps with weight loss, but have noticed a complete change in appetite and the lack of needing to snack during the day. I feel this plan will work for me in my goal to lose 20 lbs and will help keep the weight off due to forcing a lifestyle change in my exercise and activity levels being increased. The key is having the desire for change, and Wegovy assists in that."

• Slo...
• Taken for 1 to 6 months
• April 3, 2023

For Weight Loss (Obesity/Overweight) "Starting week 9 with the second injection of 1 mg. I have lost 24 pounds in 8 weeks. The side effects happen about 3 - 4 days a week. The first weekend on 0.25 mg was the worst! I really thought I needed my last rites! I have had headaches, nausea, vomiting, and bowel issues but not like the first-week episode. I try to eat light the day of the shot and take it at night because it makes me tired. You have to stay positive and just buy meds that will help with side effects because the side effects will probably always happen a couple of days a week. Try to drink 1/2 gallon of water a day and stay away from red meat, fried food, fast food, (most) dairy and sugar. If you don't, you will feel sick from eating that stuff. Also only eating one cup of food every couple of hours has made a huge difference in the nausea. Stock up on SF ice pops and SF Gatorade. I am so grateful that I got Wegovy with my insurance and when I want to quit, I just remember how many people would love the opportunity."

• Anonymous
• Taken for 1 to 6 months
• March 19, 2022

For Weight Loss (Obesity/Overweight) "Started 5 weeks ago, down 13 pounds. I have had little side effects with the exception of being tired more often. Just started 0.5 today."