Wegovy and Constipation: What Users Say

• JAO...
• Taken for 1 to 6 months
• June 14, 2023

For Weight Loss (Obesity/Overweight) "I had been on this drug for 4 months. Typical escalation dose until month 4, I stayed on the 1 mg. The side effects were rough since increasing to 1 mg. So much nausea, worsened reflux, constipation, bloating, burping, and indigestion. I vomited once, but there were a few times I almost did. In the last few weeks, I noticed hair loss. Noticed skin tags that I have never had...like 3 grew since the med. Weird. Oh, and I had serious issues with certain smells. I had to change out the hand soaps in my house 5 times. If I smell rubbing alcohol, I am instantly nauseous. Just looking at the Wegovy box before injecting would make me dizzy and nauseous. So weird. Difficult to eat healthy on this med due to side effects, and only able to tolerate simple carbs, low-fat diet. Also hard to work out when feeling so nauseous...so didn't think it was contributing to my health. Has not really contributed to weight loss, and appetite is almost the same as before med."

• WmB...
• Taken for less than 1 month
• June 13, 2023

For Weight Loss (Obesity/Overweight) "Wegovy hasn't resulted in any weight loss. At times, I'm nauseous, full, and constipated regularly. Also, the injection device failed to work, no clicks or moving yellow bar. The product failed to go in and leaked all over, thereby causing me to get no shot/dosage."

• Dan...
• Taken for 1 to 6 months
• April 5, 2023

For Weight Loss (Obesity/Overweight) "I wanted to warn people of the side effects, as my doctor did not prepare me for this med. I am very glad I didn't try to work, otherwise, I would have lost my job or, at the very least, been written up for various reasons. On it for a month. I tried spacing out the second shot and never ended up taking the last injection. Side effects: severe fatigue, severe hair loss, decreased hormones, severe headaches, changes in your sleep architecture, bad nightmares for all sleep, naps, and overnight. Warning: if you have PTSD, that may mess with you. Bladder urgency and UTI symptoms started on day 3 and were constant the whole time on the med, I had to take AZO. Bloating, burping, throwing up, and all food smells make you sick, severe constipation, hypoglycemia, and increased binge eating. I also had increased topical psoriasis and arthritis pain. Started having problems with my foot and wondering if it's impacting ligaments. I am getting that checked out. Did not reduce the need to eat, no weight loss."

• fin...
• Taken for 1 to 6 months
• January 17, 2022

For Weight Loss (Obesity/Overweight) "Took it for 8 weeks, made it through the 2nd titrated dose and couldn't handle it anymore. Nausea, gas, bloat, constipation, diarrhea, and it was worse at night while lying down. Never improved, but actually got worse by week 8. Not sure how anyone makes it to the full dose. Also did not drop a single pound. There were days I only consumed 600 calories and still felt awful. I read another review very similar and agree that you absolutely cannot eat anything spicy. Bland food days were better but there are not enough antacids and constipation meds in the world to make me want to lose 20 pounds this badly. Took my last dose 10 days ago and am still dealing with residual GI upset. Hope physicians are more forthcoming about the side effects and do not tell patients they happen but subside in a couple of days - they do not."

• Kay...
• Taken for 1 to 6 months
• May 18, 2023

For Weight Loss (Obesity/Overweight) "I’ve been on Wegovy for 3 months and have gained 2 lbs. I have had side effects such as severe constipation, fatigue, and issues with my menstrual cycle. I am glad other people have had positive experiences with this drug, but it’s definitely no miracle. I decided I can make healthy changes without this medication. I stopped using it."

• Don...
• Taken for 1 to 6 months
• March 13, 2023

For Weight Loss (Obesity/Overweight) "I have had severe nausea and stomach pains, constipation, and back pain. Have had to stop taking it."

• Jji...
• April 2, 2023

For Weight Loss (Obesity/Overweight) "Awful. I felt tired and like I had morning sickness the whole time. Was on one month of .25 mg and two months on .5 mg. It never got better. I was constipated and on the verge of throwing up constantly. Also started post-menopausal bleeding despite being on HRT. All of this, and I only lost a whopping 9 pounds despite barely being able to eat even cereal. Your diet turns to garbage because you just stick to stuff that won’t make you feel more nauseous. You will not learn how to eat properly; just how not to eat foods that make you throw up. I just switched to phentermine, and I’ve already lost two pounds in 5 days. My energy is back. Zero side effects and less than $15/month. Read the long-term reviews, people. Unless you are going to stay on this for life, which I would never do seeing how it messed with my hormones, you will 100% gain it all back and then some."

• Tou...
• Taken for less than 1 month
• March 14, 2023

For Weight Loss (Obesity/Overweight) "I am on my 3rd 0.25 dose of Wegovy. I feel terrible most of the time. I have lost 5 lbs and am definitely not hungry due to nausea. My prescriber will not prescribe Zofran with Wegovy because she feels nausea that severe should be considered a negative side effect and the medication stopped. That's reasonable. I read the reviews before I began the med and take Omeprazole daily, as well as Miralax. I am 57, menopausal, and used to feel really good most of the time. Sadly, this med is not worth the side effects for me. I really, really wanted to tough it out, but as a nurse, I feel it's creating problems that I did not have before taking this medication. The nausea is constant, the belching/burping is so frequent that it's embarrassing, stools are like a rock, and the worst feeling is chest tightness. I had so hoped I would be one of those without adverse side effects, but I am not."

• Mel...
• Taken for less than 1 month
• March 9, 2023

For Weight Loss (Obesity/Overweight) "Week 2: I have not had any appetite suppression, just very bad constipation. I've had to take stool softeners with every meal and use glycerin suppositories to unplug my colon. No weight loss yet."

• Why...
• Taken for 1 to 6 months
• April 10, 2022

For Weight Loss (Obesity/Overweight) "I tried the 0.25 dose and experienced constipation. The next month, my doctor prescribed 0.5. Not only did the constipation continue, there was horrible burping, severe indigestion that caused me to take a day off work. After that, I didn't eat much, just drank water, peppermint tea, smoothies. In addition to those side effects, there's also the possibility of life-threatening side effects. While it was easy to administer, I'd rather stay fat than endure the pain of side effects or additional medical issues to increase weight loss."

• Jam...
• Taken for 1 to 6 months
• February 2, 2022

For Weight Loss (Obesity/Overweight) "I’ve been on Wegovy (Ozempic) for 10 weeks, first at 0.25 mg and now on 0.5 mg. I have not lost any weight (but not gained any). It has not curbed my appetite, and I still crave sweet stuff. I have had a few side effects, but the worst is constipation, and I have not had a normal poo since I started. I also have a headache, get dizzy if I stand up quickly, and my hair is falling out somewhat. I eat high fiber and take psyllium husk, and still no poo in a week sometimes. I would stay on it at higher doses, but the cost of £155 per month is not worth it if no effect so far. Disappointed because so many have a good result with this medication."

• Jol...
• Taken for 1 to 6 months
• November 24, 2024

For Weight Loss (Obesity/Overweight) "I started on Wegovy .25 mg mid-August and felt no side effects but no weight loss neither. Difficult stool movement right away. After 6 weeks, I started taking .50 mg after difficulty finding this dose in any pharmacy in Miami. I stayed on this dose for 4 weeks without any weight loss or bad side effects, other than constipation. Then I started taking 1 mg and immediately started feeling very bad: severe nausea and indigestion and bad diarrhea. Obviously, you can’t eat anything, so yes, I finally started losing weight, but felt so bad, I could not function, slept a lot, did not eat, was on the toilet a lot, and decided this was not worth it and stopped after two injections. Perhaps other people can deal with these kinds of side effects or they just react easier. Since I started on low doses for so long, I was disappointed the side effects were still so strong. After about three days (after stopping), I feel normal again but weight comes back quickly if you don’t have an iron will!"

• Cha...
• Taken for 1 to 6 months
• March 13, 2022

For Weight Loss (Obesity/Overweight) "Just completed my first month on Wegovy. I was on the 0.5 dose and only lost 5 pounds. Was a little disappointed that was all I lost. Today started on the 1.0 dose, hoping to lose more weight than just 5 pounds a month. Doing low carb. Feel bloated and experiencing constipation."

• Fay...
• Taken for 1 to 6 months
• April 6, 2025

For Weight Loss (Obesity/Overweight) "I’ve been on Wegovy for 3 months and have lost 18 lbs. I have had constant heartburn and constipation. I really haven’t felt good since I began with Wegovy. Stool softeners and an occasional suppository have helped. I keep hoping the heartburn will improve, but it doesn’t. Using liquid Mylanta for temporary relief. Think twice before starting. It’s definitely not a pleasant way to lose weight."

• ano...
• Taken for 1 to 6 months
• February 3, 2025

For Weight Loss (Obesity/Overweight) "On Wegovy 0.25 for 8 weeks with little effect. Now, starting 0.5 and hoping appetite suppression will start. I'm mid 80's, 230 pounds. The only side effects thus far are constipation and some drowsiness. Fiber gummies help the former, as does an occasional Colese tablet. A short nap helps the tiredness. I'm sticking to my normal diet but trying to eat less so my wife does not have to prepare different meals for me. Given my normal diet, I've read that losing 30 to 35 pounds over six months is a reasonable expectation."

• Fay...
• Taken for less than 1 month
• January 22, 2025

For Weight Loss (Obesity/Overweight) "I started Wegovy 2 weeks ago. I have acid reflux and constipation. I took 1 magnesium/citrate gummy to help with the constipation and ended up with severe cramping with diarrhea in the middle of the night. The acid reflux happens every evening, and acid reflux meds cause constipation. I’m not enjoying the Wegovy."

• kon...
• Taken for less than 1 month
• October 11, 2024

For Weight Loss (Obesity/Overweight) "A lot of stomach issues, especially severe constipation and nausea."

• ATT...
• Taken for less than 1 month
• June 1, 2023

For Weight Loss (Obesity/Overweight) "I am currently on my third-week dose of 0.25 mg, and my starting weight was 155 lbs. I am currently fluctuating between 146 - 148 lbs. I feel great, and I have had minimal side effects of constipation (fixed with Miralax and papaya) and some nausea. Can't wait to go up on my dose!"

• Anonymous
• Taken for 1 to 6 months
• May 3, 2023

For Weight Loss (Obesity/Overweight) "My experience so far is positive: 21 lbs down in 8 weeks. First, 4 weeks on .25 mg was great, no side effects. Weeks 5 and 6 were also good, slightly uncomfortable stomach but not bad, weeks 7 and 8, with 7 being not so bad. Then week 8, I had more stomach pain for a few days and didn’t have much of an appetite. Constipation is a real thing on this medication. Also, I am having a fast heart rate and seem to be a slight case of anxiety. Although I am experiencing some side effects, I am not giving up yet. I think for me, staying on a lower dose might be best. The .25 mg does work with fewer issues."

• Mer...
• Taken for 1 to 6 months
• December 29, 2021

For Weight Loss (Obesity/Overweight) "I have been on it for 2 months. I am at .5 right now and have lost 18 pounds. That’s great, but I am exhausted lately and very constipated. Going to my primary on Friday for blood work. If the side effects continue, I will have to stop."

• Ano...
• Taken for 1 to 6 months
• May 7, 2025

For Weight Loss (Obesity/Overweight) "I have done very well with Wegovy. I am now on the highest dose. This is the 3rd week on the highest dose, and I have lost 25 lbs in 4 months, and I am still losing. I have had some common issues such as nausea, diarrhea in the first month, but that went away. Then in the 2nd month, I had minor stomach pain, and the diarrhea changed to constipation. I am still experiencing constipation but managing it with fiber. Other than these issues, I am happy with the medication, and I feel so much better!"

• Ste...
• Taken for 1 to 6 months
• March 14, 2025

For Weight Loss (Obesity/Overweight) "Been taking Wegovy for 2 months now. First month, very little side effects & lost 14 lbs. Second month, moved up to the 0.5 dose. Stomach issues started, mainly rumbling noises with diarrhea/constipation. Has gone on for weeks now (not days), so have referred myself to my GP."

• Joh...
• Taken for 1 to 6 months
• March 9, 2025

For Weight Loss (Obesity/Overweight) "I have been on Wegovy now for two months and have lost 20 pounds. The only issue I have had since starting is constipation. I tried various laxatives, but it took a long time for them to kick in. They have started to work, which is awesome as I was getting concerned. I am a 75-year-old male and started at 235 pounds. I have dropped 20 pounds so far and would like to lose that much again. I have more energy, have dropped from size 40 pants to a very loose 38. As I said, my only issue has been the constipation, but maybe I need to increase my water intake to offset that. I would recommend this product, but the side effects are not the same for everyone. Best of luck to all."

• Cat...
• Taken for 1 to 6 months
• February 2, 2025

For Weight Loss (Obesity/Overweight) "Feeling very full after eating, I have some nausea and a little bit of discomfort. It is a bit constipating, which is annoying as I would rather not have to rely on stool softeners."

• Wyg...
• Taken for 1 to 6 months
• December 18, 2024

For Cardiovascular Risk Reduction "Constipation, belching, and pleuritic chest pain. I have lost 17 lbs in 6 weeks."