Wegovy and Heartburn: What Users Say

• Peg...
• Taken for 1 to 6 months
• May 16, 2023

For Weight Loss (Obesity/Overweight) "Have been using this Wegovy for about 3 months with absolutely NO results. I do get really bad heartburn after my injections. I'm on the highest dose that you can be on, and it hasn't helped with suppressing my appetite at all. Worthless drug. Don't waste your money. I gave it my all, and I'm done with this stuff."

• Bob...
• Taken for less than 1 month
• July 23, 2022

For Weight Loss (Obesity/Overweight) "Horrible experience after taking just the first dose. I’m going on my third week of being out of work. I have never been this sick. Violently vomiting one hour after my first and only dose. Heartburn, no energy, brain fog, couldn’t even speak coherently for the first 48 hours after taking. This stuff is like poison. Do not take it."

• Kma...
• Taken for 1 to 6 months
• January 10, 2022

For Weight Loss (Obesity/Overweight) "First of all, this does work. I lost over ten pounds in 6 weeks. The weight just fell off. Second of all, this was the worst experience I have ever had with a prescribed medication. Well, I started at the lowest dose and took that for 4 weeks before moving to the next dose, which I believe was 0.5 mg. The maintenance dose is 2.4 mg, I believe. How anyone makes it to the 2.4 mg is beyond me. I made it to the second dose of 0.5 mg before I threw in the towel. This stuff is WICKED. I spent 6 weeks of my life with an upset stomach, the absolute worst reflux and heartburn I have ever had, and constant nausea. I had to literally force myself to eat. Would not recommend. The side effects and the price are not worth it. Easy to lose weight when you are starving yourself and feel too sick to eat. Once I stopped, it took a few days to feel better and the weight came back lightening quick plus a few. Not worth the misery in my opinion."

• AMa...
• January 2, 2022

For Weight Loss (Obesity/Overweight) "I’m on Week 15 of treatment and have lost nothing. On the first dose of 0.75 mg, I experienced heartburn, fullness, and zero appetite for 5 days. I was hopeful that it had finally started to work. On subsequent doses of 0.75 mg and 1 mg, and now on 1.7 mg, I’ve felt no effects from Wegovy. I’ve tried switching injection sites from my abdomen to my arm with no effect."

• Anonymous
• Taken for 1 to 6 months
• May 24, 2023

For Weight Loss (Obesity/Overweight) "Easy to administer, but during the first few weeks, had zero weight loss. Dose was increased. Woke in the middle of the night after the last dose with severe heartburn. Vomited every four hours for two days. Missed a day of work. Not able to keep anything down, including water. Put on anti-nausea medication. Have to sleep in a sitting position and take antacids and prescription meds to control heartburn enough to sleep. Cannot wait for the medication to get out of my system so I can function without vomiting or constant heartburn."

• Jan...
• Taken for 1 to 6 months
• February 8, 2022

For Weight Loss (Obesity/Overweight) "I am on week 6, .5. So far, it has not done much other than a little heartburn and extra gas. Have not lost weight and actually gained a few pounds, has not curbed my appetite, so to be fair, I have been eating more than I should because of my appetite still there. Hanging in there and hopefully I will see a change going forward. The side effects have not been enough to make me give up."

• Che...
• Taken for 1 to 6 months
• April 20, 2023

For Weight Loss (Obesity/Overweight) "I lost 15 lbs on my own, then joined a diet program and lost another 40 lbs. I plateaued for 6 months, then saw a weight loss doctor who put me on Saxenda (the daily injection) since Wegovy was not available. In 10 weeks, I lost 6 lbs. I never felt this fullness people have talked about. When Wegovy became available, I was started at the second highest dose and felt great the first week, but then got severe heartburn and nausea. At the highest dose, my side effects disappeared. During the 24 weeks I was on Wegovy, I really never had a full feeling. I lost 4 lbs in that period. I decided to stop since I did not get my insurance to approve my refill in time. I have gained back some of the weight even though I am eating the same number of calories and still exercising 300 min/wk. I am still gaining my 10 lb loss back."

• Deb...
• Taken for less than 1 month
• December 12, 2024

For Weight Loss (Obesity/Overweight) "The first four days have been really rough. I’ve experienced nausea, vomiting, severe heartburn, and stomach pain. I really want this to work, so I’ll continue. The doctors have had to prescribe nausea and vomiting medicine. It helps. I’m taking Alka-Seltzer for the heartburn. I’m really hoping the side effects will stop."

• Jen...
• Taken for 1 to 6 months
• April 7, 2023

For Weight Loss (Obesity/Overweight) "I have been on Wegovy for 8 weeks now (0.5 mg dose). I had occasional nausea, but this week I had diarrhea, vomiting, gas, nausea, and stomach pain. Thank goodness I was able to work from home, otherwise, I would have had to call out. I thought I had the stomach flu, but now I wonder if it's the medication. I am supposed to move up to the 1 mg in two days, but I am scared to. I took Ozempic for two months, and the only side effect I had was horrible heartburn, but it was very difficult to get, so I had to switch. I am contemplating not taking this anymore. I can handle some nausea, but to be so sick you can't function is a whole other thing. And I have not lost any weight."

• KB6...
• Taken for 1 to 6 months
• January 28, 2022

For Weight Loss (Obesity/Overweight) "Have been on the drug for four months and have lost 14 lbs. Now on 1.7 mg dose and have had intense nausea off and on for the last 3 weeks. Prior to this, on lower doses, nausea was milder, but heartburn and reflux were worse. If this kind of nausea persists, I don’t think I can stay on the drug much longer. It’s just too brutal to be so nauseated and tired for so much of the day."

• Fay...
• Taken for 1 to 6 months
• April 6, 2025

For Weight Loss (Obesity/Overweight) "I’ve been on Wegovy for 3 months and have lost 18 lbs. I have had constant heartburn and constipation. I really haven’t felt good since I began with Wegovy. Stool softeners and an occasional suppository have helped. I keep hoping the heartburn will improve, but it doesn’t. Using liquid Mylanta for temporary relief. Think twice before starting. It’s definitely not a pleasant way to lose weight."

• Ano...
• Taken for 6 months to 1 year
• April 16, 2025

For Weight Loss (Obesity/Overweight) "Lost 5 kg first 2 weeks on 0.25, on 0.5 now 6 months and lost nearly 40 kg, 200 mm from gut, helps with knee and hip pain. Very happy. Only side effect is heartburn for me. Not going any higher on dose as per doctor advice."

• Lal...
• Taken for 1 to 6 months
• June 10, 2023

For Weight Loss (Obesity/Overweight) "I started 3 weeks ago, and every Monday I inject myself with a 0.25 mg dose. I started this medication because at age 47, even though I tried so hard to exercise and diet, my weight was a roller coaster ride and I would bounce back to my heaviest weight. My weight when I started was 170 lbs, which was 3 weeks ago. After a week, I am down to 159 lbs, then the second week 157 lbs. I weighed myself yesterday and I am down to 155 lbs, that's 15 lbs less. The first week I had a little heartburn, and the second week I was a little dizzy because you can go a day without being hungry at all. By the end of the second week, I had no side effects at all. I am surprised that again I can go a day without being hungry at all, but of course, I force myself to eat something, even with food, I will eat but will be so full easily. I take protein shakes daily as my meal replacement. I'm taking fiber (gummies) so I can go to the bathroom with no problem, and it helps a lot. Overall, I am pretty happy with the result."

• Wan...
• Taken for 1 to 6 months
• May 3, 2023

For Weight Loss (Obesity/Overweight) "I’ve been on Wegovy since February. I started on 0.25 mg and am now on 1.7 mg. Each month I have gone up a dose and injected it in my thighs. I was at 207 lbs and now I am at 190 lbs. But every time I inject myself, the next morning I vomit the little I ate the night before. I am always feeling nauseous after I eat and I know my limits now, but I always have that feeling that I will vomit. I always get heartburn and I’m always burping."

• yir...
• Taken for less than 1 month
• May 2, 2023

For Weight Loss (Obesity/Overweight) "I started Wegovy .25 mg on March 5th. On day 1, I felt a little nausea and a little tired. Felt fine the rest of the week, appetite suppressed after a day or so. Continued to follow a healthy diet, exercised at least 5 days a week, and meal portions became smaller. I did not experience any other side effects aside from a little heartburn at night after the 2nd dose. By the 3rd dose, I started feeling somewhat constipated and noticed my watch was notifying me more frequently than usual that my heart rate was over 100 throughout the day and night. I take blood pressure medication, so I decided to call my doctor. She does want me to get blood work done and will be checking my thyroid. Also recommended I stop taking the med. I am a bit worried as I already feel the cravings are coming back. After I complete blood work, I will provide additional feedback regarding recommendations from my PCP. I have lost about 14 lbs., so it does work. I would give it a shot, everyone reacts differently."

• Mon...
• Taken for 1 to 6 months
• April 17, 2023

For Weight Loss (Obesity/Overweight) "Just finished my fourth injection of 0.25 mg. The first 3 weeks were a breeze. I had mild nausea, fewer cravings, sometimes had to make myself eat. Today, right before my fourth injection, I am experiencing severe heartburn and indigestion, which are very painful. Tums don’t work, so I’m taking Nexium for some mild relief."

• fam...
• Taken for less than 1 month
• March 31, 2023

For Weight Loss (Obesity/Overweight) "3 weeks in and it has caused lots of nausea and heartburn."

• Lau...
• Taken for 1 to 6 months
• June 2, 2023

For Weight Loss (Obesity/Overweight) "So far, I love it. Did 0.25 mg for 4 weeks and lost 5 pounds (SW 162; GW 135). I just started the 0.5 mg injection this week. I don't have any of the negative side effects, such as nausea, vomiting, etc. Have had a little heartburn, but manageable with Pepcid AC. It has helped curb my appetite some and helps me control myself not to overeat, but it's not magic. I'm hopeful the appetite suppression will increase as my dosage increases. My only concern is that the 1.0 mg will not be available when I need it."

• eli...
• April 3, 2023

For Weight Loss (Obesity/Overweight) "Started on 0.25 mg. Had some side effects but not enough to stop taking it. Nausea, but not terrible, heartburn which was bad at times, Pepto-Bismol sorted it out (have some on hand). Curbed appetite, but noticed it starting to not be so effective when it was time to up the dose. I am now on 0.5 mg. The third week, and I am on a new dose, and there's a big change. I have heartburn most of the time, especially if I try to eat starchy carbs (1 slice of bread). Nausea here and there, but since I took the third dose of 0.5 mg, I have absolutely zero appetite. I know I should eat, but 1 or 2 mouthfuls of food is enough for me. I lost 12 lbs in the first month and will weigh myself at the end of the second month. Conclusion: if you really can't stop eating, and your health is suffering, speak to your doctor about Wegovy. It's not a magic wand, but will definitely help you. Make sure you drink plenty of water throughout the day."

• Ano...
• Taken for 1 to 6 months
• April 9, 2025

For Weight Loss (Obesity/Overweight) "No adverse side effects. Just took 8th injection and last at 0.5 mg. Next week, dosage goes to 1 mg. Down 16 pounds in 7 weeks. I was already taking Metamucil every morning, so no constipation as some have reported, but I am having less bowel movements now. I imagine I would be constipated without it. Also take Nexium daily, so heartburn really hasn't been an issue more than it already was. Started at 6 ft and 251 pounds. Was 235 today. Goal is between 180 and 200."

• Bre...
• Taken for less than 1 month
• March 8, 2025

For Weight Loss (Obesity/Overweight) "I’ve been on Wegovy 0.025 for only 2 weeks, and I’ve lost 7 lbs. I was 245, now I’m 238. This is a miracle drug. Only side effects are a metallic taste and heartburn. I’m not going to give up. I’ve been eating Healthy Choice TV dinners and loving the high protein and low-calorie meals. I’ll chat again in 2 weeks."

• Ros...
• Taken for 1 to 6 months
• November 1, 2024

For Weight Loss (Obesity/Overweight) "Hashimoto's, 5'3" overweight. Not yet obese, but pretty close. Lost 17 pounds in 6 months. Effortlessly. I thought I only lost 5 pounds. I noticed a difference in my clothes but thought it was my imagination. Didn't really modify my diet, just stopped eating when I felt full. Best dose, max dose. Side effects are heartburn, but that's if I ate like I did before. Calories a day: 1700, desk job, not a lot of exercise, and still lost weight. Before, 17 pounds larger, fasted for 20-24 hours at 1200 calories and body inflamed. My cholesterol now is healthy. Sleep is better. Less apnea episodes, to my surprise."

• Dut...
• Taken for 1 to 6 months
• September 6, 2024

For Weight Loss (Obesity/Overweight) "I'm almost 2 meters long, and when I started, I was more than 157 kg. Within 11 weeks, I lost 22 kg. Almost every week, I lost 1.5 kg and more after the big water loss. For me, it's an addition to the bigger plan. Yes, I use Wegovy (now on 1 mg), but I also go to the gym 5 times a week and add some hour-long walks to my day. And yes, I also have a strict timeframe where I have my meals. And yes, they are mostly veggies and some yogurt with some granola for some fiber. I had some side effects like heartburn, burping, constipation, and I'm more tired than before. But I think that's a normal thing to process, especially when you make the transition. If you are seriously overweight, please consider this medicine as a small part of the bigger plan!"

• Rob...
• Taken for less than 1 month
• July 24, 2024

For Weight Loss (Obesity/Overweight) "I have taken 1 dose of the 0.25 mg. Tomorrow I will be taking my 2nd dose. So it has been 6 days for me. I have already lost 4 lbs. I was very nauseated and had some heartburn the first 24 hours after I took the dose. It got better with Pepto-Bismol and Tums. I didn't really get sick after that day. I don't have an appetite at all. I eat enough to keep me healthy, no more. I have gotten mild nausea once when I ate some chocolate chip cookies, but no nausea with healthy foods like fruit and veggies. I haven't done much exercise either."

• Hit...
• Taken for 1 to 6 months
• June 27, 2024

For Weight Loss (Obesity/Overweight) "Started Wegovy on May 11th at 0.25. I'm on my 4th injection of 0.5 and moving up to 1.0 next week. Started at 228 lbs. I'm down to 213. No side effects. I have to eat a small dinner and not too close to bedtime or I get heartburn. Slow and steady wins the race. Wegovy is the most effective appetite suppressant I have ever used, and best of all, no jitters or sleeplessness."