Wegovy and Diarrhea: What Users Say

• 188...
• Taken for 1 to 6 months
• May 17, 2023

For Weight Loss (Obesity/Overweight) "Started Wegovy 3 months ago using the gradual phase-up method. From 0.25 mg dose for 4 weeks to 0.50 mg dose for 4 weeks, then 1.0 mg dose for 4 weeks. During the initial phase, I experienced mild nausea and some stomach irritation. With each increase, the symptoms got worse until finally, at the full 1.0 mg dose, I was so sick I thought I had stomach flu for 2 weeks continuously. The belching was horrible. The nausea caused uncontrollable vomiting, and I had frequent diarrhea. After 3 months, I lost 12 pounds and felt horrible every day. I've now reduced the dose to 0.5 mg but still suffer from nausea and stomach upset. I might cut back again, but I'm thinking I will quit. The way I feel all the time is horrible! I'm thinking I lost weight because of all the vomiting. Not recommended."

• Gab...
• Taken for 1 to 6 months
• July 9, 2022

For Weight Loss (Obesity/Overweight) "Horrible, I had smelly sulfur burps and nausea at 1.7 mg. After the 2.4 mg limit, I became violently ill for two days. It was projectile from both ends. Very embarrassing. After that, just constant diarrhea for days. Throw it in the garbage."

• Anonymous
• Taken for less than 1 month
• January 22, 2022

For Weight Loss (Obesity/Overweight) "Worst experience of my life. After the second 0.25 dose, I was up all night vomiting and diarrhea. The next day, I had chest pain, shaking, brain fog, stomach pain, more diarrhea, and had to go to the ER. After they gave me Benadryl and morphine, I started to feel better. Still have burping, gas, and acid reflux terribly. WILL NEVER TRY THIS AGAIN! It is not worth it to me! Wish it would hurry up and get out of my system."

• fin...
• Taken for 1 to 6 months
• January 17, 2022

For Weight Loss (Obesity/Overweight) "Took it for 8 weeks, made it through the 2nd titrated dose and couldn't handle it anymore. Nausea, gas, bloat, constipation, diarrhea, and it was worse at night while lying down. Never improved, but actually got worse by week 8. Not sure how anyone makes it to the full dose. Also did not drop a single pound. There were days I only consumed 600 calories and still felt awful. I read another review very similar and agree that you absolutely cannot eat anything spicy. Bland food days were better but there are not enough antacids and constipation meds in the world to make me want to lose 20 pounds this badly. Took my last dose 10 days ago and am still dealing with residual GI upset. Hope physicians are more forthcoming about the side effects and do not tell patients they happen but subside in a couple of days - they do not."

• Anonymous
• Taken for 1 to 6 months
• June 21, 2023

For Weight Loss (Obesity/Overweight) "I have lost 37 lbs in 3.5 months, but should be more due to the horrific side effects. Burping, belching, vomiting, diarrhea, chest pain, nausea, blurry vision, basically every side effect imaginable. I never had side effects from any medications before. I continued to increase the dose up to 1.7 mg and hope for the best with no success. I have three more weeks of misery, but due to the cost of $586, I refuse to trash this medication."

• Xim...
• Taken for less than 1 month
• June 19, 2023

For Weight Loss (Obesity/Overweight) "I started taking Wegovy one week ago. I have had 2 injections of 0.25 mg. It feels like I have never been this sick before. Terrible cramps and diarrhea since day 3. I have heard about side effects, but I was stubborn and wanted to try. I regret doing it. I learned my lesson. Needless to say, I will stop the treatment. I am sure I have lost some weight. I am not retaining any food. A few minutes after eating, I have to go to the bathroom. I am glad to hear it has worked for many people. This medicine is certainly not for me."

• Bpm...
• Taken for less than 1 month
• April 22, 2023

For Weight Loss (Obesity/Overweight) "After being on another weight loss drug for 6 months and losing 35 lbs, my PCP and I decided to try Wegovy. I am currently on 0.25 mg and on my fifth day. After the third day, I have been experiencing gas and diarrhea. Nothing that can’t be handled, in fact, it has started to subside. My only concern is that it doesn’t seem to curb my appetite. I had bariatric surgery in 2015, so I don’t have a huge appetite, but am worried that the current dose of 0.25 mg of Wegovy that I am currently on is not working. I am hoping it will take a few days to kick in."

• Sar...
• Taken for less than 1 month
• April 10, 2022

For Weight Loss (Obesity/Overweight) "Made me terribly sick. Took only 0.25 dosage one time, had terrible diarrhea, extreme exhaustion, and some nausea. Definitely not taking the second dose. Not worth the pain. Did not lose any weight either. It stops you from eating because it makes you feel so bad if you do. I also think this drug is meant for someone who doesn’t live an active lifestyle. I work out all the time, I eat healthy, and really just wanted to drop 15 lbs. This drug was very disappointing."

• Dee...
• Taken for 1 to 6 months
• April 10, 2023

For Weight Loss (Obesity/Overweight) "I wish I did more research before starting this. I started on Saxenda and worked up to 3.0 mg, the max dose. I had a few bouts of severe diarrhea and vomiting. I lost a total of 15 pounds and then started getting ravenous. Then I got switched to Wegovy 2.0 mg and then moved up to 2.4 mg. I only had a couple of incidents of terrible nausea, usually when I ate greasy, heavy, or fried foods. But generally, I feel like crap every day. Once on the Wegovy, the weight literally fell off. Mostly because I just didn't think about eating anything, or my appetite would be satisfied with a very small portion of food. The biggest side effect is skin irritation; like a constant sunburn. Clothes touching my skin bother me. Or riding in a car and bouncing. It became intolerable. And chills make my skin ache. I easily surpassed my goal weight and now trying to decide if I want to quit it altogether or reduce the dosage and hope the skin irritation goes away."

• Lis...
• Taken for 1 to 6 months
• January 29, 2022

For Weight Loss (Obesity/Overweight) "I started Wegovy 8 weeks ago. The coupon made it $25 a month. On the dose of 0.25, I had nausea and occasional diarrhea. On my 7th injection dose of 0.5, I got very sick: extreme nausea, diarrhea, and stomach pains. I skipped my next dose. I have been to the emergency room twice for fluids and anti-nausea medicine. The diarrhea is the worst of it-nonstop. I cannot keep anything down. I am down 23 pounds but feel miserable. I hope the medication wears off soon. I do not recommend the medication, it makes you feel so sick."

• Jol...
• Taken for 1 to 6 months
• November 24, 2024

For Weight Loss (Obesity/Overweight) "I started on Wegovy .25 mg mid-August and felt no side effects but no weight loss neither. Difficult stool movement right away. After 6 weeks, I started taking .50 mg after difficulty finding this dose in any pharmacy in Miami. I stayed on this dose for 4 weeks without any weight loss or bad side effects, other than constipation. Then I started taking 1 mg and immediately started feeling very bad: severe nausea and indigestion and bad diarrhea. Obviously, you can’t eat anything, so yes, I finally started losing weight, but felt so bad, I could not function, slept a lot, did not eat, was on the toilet a lot, and decided this was not worth it and stopped after two injections. Perhaps other people can deal with these kinds of side effects or they just react easier. Since I started on low doses for so long, I was disappointed the side effects were still so strong. After about three days (after stopping), I feel normal again but weight comes back quickly if you don’t have an iron will!"

• Sid...
• Taken for less than 1 month
• June 22, 2023

For Weight Loss (Obesity/Overweight) "Administered my first (and last) shot Tuesday, 6/20. Starting about 9 hours later that day, it's been vomiting and diarrhea nonstop. Can't keep ginger ale down, can't keep dry toast down. Can't keep plain crackers down. I have no clue where the stuff coming out of me is coming from. I wasn't a big eater prior to the injection, just with my age, I can't seem to drop pounds. With what I've been going through the last 48 hours (and still am), I will not be taking any further injections. Hope it works for all of you, but not for me."

• Cor...
• Taken for 1 to 6 months
• June 9, 2023

For Weight Loss (Obesity/Overweight) "Last night, I had my first injection of 1 mg strength (week 3). I have gastrointestinal issues of bloating, eructation, diarrhea, and abdominal pain, LUQ 3-4/10 pain. It feels like a stomach virus, chills, but afebrile. Fatigue and anorexia. Only lost 5 lbs, but think it’s due to significantly reduced food intake."

• Cal...
• Taken for less than 1 month
• May 12, 2023

For Weight Loss (Obesity/Overweight) "My experience with Wegovy has been a rollercoaster. In the first week, the 0.25 mg dose was great. In the second week, I started feeling the side effects of nausea, burping, gas, diarrhea, and bloating. I noticed that I did eat more. Make sure your portions are small and stick to fruit and vegetables. Soups and not greasy processed foods. You may feel sick and will take longer to digest. I am currently reconsidering if I should continue. I am not sure if I want to experience the side effects at a higher dose. I feel terrible all the time and have a headache. I feel exhausted all the time."

• Dog...
• Taken for 1 to 6 months
• April 10, 2023

For Weight Loss (Obesity/Overweight) "I’ve been on the lowest dose of Wegovy for 3 weeks now. I was one of those that dealt with nausea within my 3rd injection, so bad I had to have Zofran prescribed. I started taking my Zofran, only needing 1 pill a day, and getting the nausea under control, only for my body to respond with loose stools. It is now day 5 of the stomach issues, and when I tell you this shot has TAKEN me out, I mean completely stopped my world. At first, I thought I had a stomach virus the first few days, but knew it could be the shot as well. Then as it progressed, I started thinking something else serious was wrong with me. The abdominal pain from my stomach just being exhausted from all that it’s going through is intense! One of the main reasons I chose to go to the ER to ensure this wasn’t something serious. X-ray and labs showed everything to be normal, so the doctor ruled it as the injection's side effects."

• Jen...
• Taken for 1 to 6 months
• April 7, 2023

For Weight Loss (Obesity/Overweight) "I have been on Wegovy for 8 weeks now (0.5 mg dose). I had occasional nausea, but this week I had diarrhea, vomiting, gas, nausea, and stomach pain. Thank goodness I was able to work from home, otherwise, I would have had to call out. I thought I had the stomach flu, but now I wonder if it's the medication. I am supposed to move up to the 1 mg in two days, but I am scared to. I took Ozempic for two months, and the only side effect I had was horrible heartburn, but it was very difficult to get, so I had to switch. I am contemplating not taking this anymore. I can handle some nausea, but to be so sick you can't function is a whole other thing. And I have not lost any weight."

• CCM...
• Taken for 1 to 6 months
• April 28, 2022

For Weight Loss (Obesity/Overweight) "Started Wegovy at the end of March 2022 on 0.25, and it definitely worked at suppressing my appetite. I had slight nausea the first two days after injection, but not too bad. I just started the .5 dose on week 5, and I’ve gotten terribly sick. I was up all night with diarrhea and vomiting, similar to food poisoning. I don’t think I will continue after this experience. Very unfortunate because it does work if you can handle the side effects."

• Ano...
• Taken for 6 months to 1 year
• April 20, 2025

For Weight Loss (Obesity/Overweight) "I started Wegovy in October at the lowest possible dosage and worked up to 1.7 by February. I had no side effects and very slowly lost weight, which I was fine with. I lost 35 pounds in six months. However, oddly enough, after five weeks at 1.7 with no side effects, I became quite ill. I started having the sulfur belches, followed by vomiting and severe diarrhea. I went to urgent care. They said it was a normal response and to take anti-diarrhea meds. I did. It got worse, to the point of diarrhea every 15-20 minutes. After six days of this, I went to the emergency room. They admitted me. I spent nine days in the hospital with severe dehydration, which caused my kidneys and pancreas to start shutting down. Docs felt I had a separate bacterial bug not caused by my shots. I was finally able to go home. My doctor had me start back at a safer .25 dose. I did, but immediately got sick again. I think I need to stop these meds, sadly, as they did originally help me, but I can’t go on this way."

• Fay...
• Taken for less than 1 month
• January 22, 2025

For Weight Loss (Obesity/Overweight) "I started Wegovy 2 weeks ago. I have acid reflux and constipation. I took 1 magnesium/citrate gummy to help with the constipation and ended up with severe cramping with diarrhea in the middle of the night. The acid reflux happens every evening, and acid reflux meds cause constipation. I’m not enjoying the Wegovy."

• Avi...
• Taken for 1 to 6 months
• July 16, 2024

For Weight Loss (Obesity/Overweight) "I am 58, have IBS-D, no gallbladder, GERD, and am 60 lbs overweight. This is my second attempt at taking Wegovy. The first attempt was disastrous! I didn't make it through the first week before I was hit with diarrhea, nausea, acid reflux, dizziness, cramps, and had headaches. I missed four days of work and went to ER twice. The doctor did tell me to stop taking this, but I honestly did not think it was the Wegovy (I had not done any research on side effects). Once I got back to my normal state of digestive issues, I became proactive. I started back on Wegovy (.25 lowest dose) 6 weeks ago, but now I take a dose of Pepto-Bismol daily (twice a day the day of and day after the shot) and I take an OTC daily antacid. I still get mild side effects (nausea, headache, and fatigue) the day after the shot or if I overeat. I have not lost any weight at this dose so I am going up to the .5 dose next week. As others have said - everyone will react to this med differently."

• blh...
• Taken for less than 1 month
• May 31, 2024

For Weight Loss (Obesity/Overweight) "First dose 0.25mg, had slight stomach pain/discomfort. Later that same night, my appetite disappeared. Just seeing a fast-food commercial on TV made me feel nauseous. I thought if that's the worst of the side effects that affect me, then I'll be very happy with that. By the next day, stomach pain and nausea increased. By 4:00 am, BAM! Diarrhea, severe stomach pain, projectile vomiting, headache, chest pain, severe itching mainly on the palms of my hands and arms. I truly thought 'this must be what it feels like to be poisoned!' I was scared. It is now the next day and I feel fine. A little tired from lack of sleep from feeling so sick. I think I will do my second dose next week...but I'm quite nervous of a repeat of feeling like I was dying from the stomach pains and vomiting. Will I continue with this drug?...jury is still out! On the positive side, I've already lost 5 pounds; but of course, I can't & don't want to eat, too much nausea and vomiting."

• Big...
• Taken for less than 1 month
• April 11, 2022

For Weight Loss (Obesity/Overweight) "Took my injection .25 mg Friday afternoon and had a very hard time eating dinner. By noon Saturday, I was violently ill with diarrhea, vomiting, and a fever. The symptoms subsided by Sunday, and I was left very achy and fatigued. On the upside, I guess I did go from 335 lbs to 318 lbs over the course of the weekend. This medication is not for the faint of heart. It is very depressing to see a full-course meal in front of you and only be able to eat a few bites. If you are serious about losing weight, this medication will get you there, but I wonder if it’ll work or if the side effects will at least subside with longer-term use. The nausea is horrible, but you do also have some beautiful dreams while taking it."

• Sam...
• Taken for less than 1 month
• October 4, 2024

For Weight Loss (Obesity/Overweight) "I am beginning to lose weight. Currently experiencing pain in the left side and diarrhea."

• Nik...
• Taken for 1 to 6 months
• May 7, 2023

For Weight Loss (Obesity/Overweight) "Checking in about my experience on Wegovy thus far. Tomorrow, Monday, May 8th, 2023, will be my second box of Wegovy 0.25 mg. So my 5th injection. I’ve lost 6 pounds since I first started. My biggest issue is diarrhea and nausea. I get occasional stomach cramping. Otherwise, I too have noticed that drinking more water seems to help. Lots of saltine crackers for me. The first week, I was scared to eat. I felt like I had the flu. It wasn’t a good experience for me. Then, gradually it let up, and by that first Friday, I felt like myself again, but still ate with caution. I have no taste! It’s odd. I know I’m eating, but it’s like I’ve lost my sense of taste. I will update after these 2 boxes are complete and hopefully will have a total weight loss that’s up to date. I don’t own a scale, lol."

• Nik...
• Taken for less than 1 month
• April 13, 2023

For Weight Loss (Obesity/Overweight) "Just started my first dose on Monday. 0.25 mg. 265 lbs 5’4. Ok for a couple of hours. Then I got nauseous and weak. I had to lie down. Day 2 felt like I had a bout of stomach flu. Diarrhea and no appetite. Ate saltine crackers and lots of water. Day 3 now and we went out to eat. I ate a chicken wrap and a Sprite. By the time we got home, I was in the bathroom with diarrhea again. Feel achy and hot! I really don’t want to give up, but if I’m going to feel like this to lose weight, then I’ll stay a plus-size woman. I will report back on Saturday. Today is Wednesday. I know quite a few people who are using this as a weight loss tool. Nothing comes easy. As soon as you stop, the weight comes back. It’s a lifestyle change."