Wegovy and Vomiting: What Users Say (Page 2)
Reviews for Wegovy
- Fay...
- Taken for 6 months to 1 year
- July 7, 2025
For Weight Loss (Obesity/Overweight) "I have been on Wegovy for 6 months. I am on the highest dosage now. It has not been a pleasant journey. I feel sick probably half the time. The worst side effect for me is constipation. I poop every 4th or 5th day. I get horrible cramps. I have only vomited 3 or 4 times. I’m waiting for the side effects to go away. I am going to stay on it for a year and re-evaluate if the side effects are worth it. I have never had chemotherapy, but I think this has similar side effects. I have lost 1 pound a week, so about 28 lbs."
- Deb...
- Taken for less than 1 month
- December 12, 2024
For Weight Loss (Obesity/Overweight) "The first four days have been really rough. I’ve experienced nausea, vomiting, severe heartburn, and stomach pain. I really want this to work, so I’ll continue. The doctors have had to prescribe nausea and vomiting medicine. It helps. I’m taking Alka-Seltzer for the heartburn. I’m really hoping the side effects will stop."
Frequently asked questions
- 6 Wegovy side effects you need to be aware of
- Ozempic Mounjaro Wegovy & Zepbound: Weight Loss Compared
- Wegovy vs Ozempic: Which is Right for You?
- How long until I'll lose weight with Wegovy?
- Sid...
- Taken for less than 1 month
- June 22, 2023
For Weight Loss (Obesity/Overweight) "Administered my first (and last) shot Tuesday, 6/20. Starting about 9 hours later that day, it's been vomiting and diarrhea nonstop. Can't keep ginger ale down, can't keep dry toast down. Can't keep plain crackers down. I have no clue where the stuff coming out of me is coming from. I wasn't a big eater prior to the injection, just with my age, I can't seem to drop pounds. With what I've been going through the last 48 hours (and still am), I will not be taking any further injections. Hope it works for all of you, but not for me."
- Jen...
- Taken for 1 to 6 months
- April 7, 2023
For Weight Loss (Obesity/Overweight) "I have been on Wegovy for 8 weeks now (0.5 mg dose). I had occasional nausea, but this week I had diarrhea, vomiting, gas, nausea, and stomach pain. Thank goodness I was able to work from home, otherwise, I would have had to call out. I thought I had the stomach flu, but now I wonder if it's the medication. I am supposed to move up to the 1 mg in two days, but I am scared to. I took Ozempic for two months, and the only side effect I had was horrible heartburn, but it was very difficult to get, so I had to switch. I am contemplating not taking this anymore. I can handle some nausea, but to be so sick you can't function is a whole other thing. And I have not lost any weight."
- CCM...
- Taken for 1 to 6 months
- April 28, 2022
For Weight Loss (Obesity/Overweight) "Started Wegovy at the end of March 2022 on 0.25, and it definitely worked at suppressing my appetite. I had slight nausea the first two days after injection, but not too bad. I just started the .5 dose on week 5, and I’ve gotten terribly sick. I was up all night with diarrhea and vomiting, similar to food poisoning. I don’t think I will continue after this experience. Very unfortunate because it does work if you can handle the side effects."
- Ano...
- Taken for 6 months to 1 year
- April 20, 2025
For Weight Loss (Obesity/Overweight) "I started Wegovy in October at the lowest possible dosage and worked up to 1.7 by February. I had no side effects and very slowly lost weight, which I was fine with. I lost 35 pounds in six months. However, oddly enough, after five weeks at 1.7 with no side effects, I became quite ill. I started having the sulfur belches, followed by vomiting and severe diarrhea. I went to urgent care. They said it was a normal response and to take anti-diarrhea meds. I did. It got worse, to the point of diarrhea every 15-20 minutes. After six days of this, I went to the emergency room. They admitted me. I spent nine days in the hospital with severe dehydration, which caused my kidneys and pancreas to start shutting down. Docs felt I had a separate bacterial bug not caused by my shots. I was finally able to go home. My doctor had me start back at a safer .25 dose. I did, but immediately got sick again. I think I need to stop these meds, sadly, as they did originally help me, but I can’t go on this way."
More FAQ
- Do Ozempic, Wegovy, Mounjaro & Zepbound cause hair loss?
- Which GLP-1 drug is best for weight loss?
- Can you get tirzepatide from a compounding pharmacy?
- Does Ozempic cause muscle loss and how to prevent it?
- blh...
- Taken for less than 1 month
- May 31, 2024
For Weight Loss (Obesity/Overweight) "First dose 0.25mg, had slight stomach pain/discomfort. Later that same night, my appetite disappeared. Just seeing a fast-food commercial on TV made me feel nauseous. I thought if that's the worst of the side effects that affect me, then I'll be very happy with that. By the next day, stomach pain and nausea increased. By 4:00 am, BAM! Diarrhea, severe stomach pain, projectile vomiting, headache, chest pain, severe itching mainly on the palms of my hands and arms. I truly thought 'this must be what it feels like to be poisoned!' I was scared. It is now the next day and I feel fine. A little tired from lack of sleep from feeling so sick. I think I will do my second dose next week...but I'm quite nervous of a repeat of feeling like I was dying from the stomach pains and vomiting. Will I continue with this drug?...jury is still out! On the positive side, I've already lost 5 pounds; but of course, I can't & don't want to eat, too much nausea and vomiting."
- RNi...
- Taken for 1 to 6 months
- May 4, 2022
For Weight Loss (Obesity/Overweight) "Wegovy does work, problem is... I feel like dirt all day long. I'm fatigued, nauseous, and even the smell of food makes me vomit. My heart races, and I'm quite dizzy. I lost 55 lbs. Do I look good? Yes. Do I feel good? No. I'm down to 153 lbs now. It's time to stop this medication."
- Big...
- Taken for less than 1 month
- April 11, 2022
For Weight Loss (Obesity/Overweight) "Took my injection .25 mg Friday afternoon and had a very hard time eating dinner. By noon Saturday, I was violently ill with diarrhea, vomiting, and a fever. The symptoms subsided by Sunday, and I was left very achy and fatigued. On the upside, I guess I did go from 335 lbs to 318 lbs over the course of the weekend. This medication is not for the faint of heart. It is very depressing to see a full-course meal in front of you and only be able to eat a few bites. If you are serious about losing weight, this medication will get you there, but I wonder if it’ll work or if the side effects will at least subside with longer-term use. The nausea is horrible, but you do also have some beautiful dreams while taking it."
- Ano...
- Taken for 1 to 6 months
- August 18, 2025
For Cardiovascular Risk Reduction "Great results, lost 25 lbs in 1 month. Nausea and vomiting, side effects, also some fatigue. Problem is I vomit my other medications."
- Ano...
- Taken for 1 to 6 months
- July 24, 2025
For Weight Loss (Obesity/Overweight) "I have used Wegovy for 3 months now. I'm a child, I'm 14, and there have been times that I threw up everything. After 3 months, I have lost 10 to 9 kilos."
- Ano...
- Taken for 6 months to 1 year
- May 17, 2025
For Weight Loss (Obesity/Overweight) "It definitely works. I have lost 15% of my weight in 8 months - almost all of it since January 2025. The side effects are really bad for me though. Stomach pain, vomiting for two days after an injection, and general nausea. I may have to stop or go down to 1%."
- The...
- Taken for 6 months to 1 year
- November 3, 2024
For Weight Loss (Obesity/Overweight) "I used Wegovy for several months with no problem and much success; I lost 20 lbs. For whatever reason-insurance, doctor, pharmacy, manufacturer-I was unable to take the drug. I restarted Wegovy yesterday at the same high dose I was taking when I stopped; suddenly, I threw up everything I had eaten. Today, I feel blah."
- Tom...
- Taken for 6 months to 1 year
- April 13, 2023
For Weight Loss (Obesity/Overweight) "Started Wegovy in March 2022 with a goal of losing 50-75 pounds. I ended up losing a total of 85 pounds in about 11 months. I felt great upon taking the Wegovy. Only had mild headaches and mild stomach discomfort. I was not tired, I actually felt energized. However, by December, the nausea had reared its ugly head. I took Zofran, and it helped. I was able to stick it out with the nausea until February, at which time I stopped taking it. I could no longer live with the nausea. Since I stopped taking it, I have continued to suffer nausea, vomiting, and stomach pain. My doctor and I are still trying to find the source of this continuing issue. I love the weight loss, and I love Wegovy!"
- For...
- Taken for 6 months to 1 year
- May 17, 2022
For Weight Loss (Obesity/Overweight) "I started Wegovy in December 2021 at 281 lbs, and as of May 2022, I am weighing in at 246 lbs (35 lbs lost). I am on the full maintenance dose at 2.4 mg. I didn't notice many symptoms early on; however, as I got to the 1.7 & 2.4 mg, my side effect symptoms greatly increased - including vomiting, nausea, diarrhea, and a nasty burnt popcorn taste in my mouth. This medication will definitely cause you to lose weight as it completely takes away your appetite, but the combination of side effects, mostly the vomiting, makes me question if I will stay on this medication much longer. For reference, I take my medication on Saturday evening and suffer the side effects until about Thursday morning. From Sun-Wed, I find myself in/out of the bathroom throwing up when I attempt to eat the most basic of foods. I used to have a large passion for food, but I can't imagine eating some of my favorite things while these side effects take over. I would recommend for those suffering to lose weight with caution."
- Lor...
- Taken for less than 1 month
- October 3, 2023
For Weight Loss (Obesity/Overweight) "I was prescribed Wegovy for weight loss purposes. I’m 5’11, 225 pounds, with a BMI of 31%, so I can be considered obese. I’ve been on it for one week and have lost 7 pounds. I’m starting with the lowest dosage (0.25). First of all, the injection was completely painless (for me). I also inject Humira bi-weekly, so maybe I’m just used to it, but I was shocked to feel absolutely nothing. I questioned if I was doing it right, it was so painless. Do not let some testimonials scare you! I did a lot of research while waiting for the drug to come back into stock. 90% of what I read were complaints about vomiting, diarrhea, some people getting so sick they had to go off of it. Some of these reviews were written after only a week or two of the drug usage. So far, my personal experience has been completely different than what I’ve read. That could change as I go up in dosage. As of right now, the only side effect I’m experiencing is a complete lack of appetite."
- Wan...
- Taken for 1 to 6 months
- May 3, 2023
For Weight Loss (Obesity/Overweight) "I’ve been on Wegovy since February. I started on 0.25 mg and am now on 1.7 mg. Each month I have gone up a dose and injected it in my thighs. I was at 207 lbs and now I am at 190 lbs. But every time I inject myself, the next morning I vomit the little I ate the night before. I am always feeling nauseous after I eat and I know my limits now, but I always have that feeling that I will vomit. I always get heartburn and I’m always burping."
- Abe...
- Taken for 1 to 6 months
- November 15, 2021
For Weight Loss (Obesity/Overweight) "Started out with .25 mg. I did that for four weeks and only felt slight nausea after the injection. Today, I bumped up to the .50 mg dose, and within five hours I was nauseous. I finally vomited, and I feel better, but have no appetite now. Nothing sounds good. I’m also sleepy. So far, the weight loss is only about five pounds. If I stay nauseated, it’ll probably increase drastically, but what a dumb way to live! I hope it’s temporary. I could be sick once a week and survive if I get decent weight loss. I am also fairly active, and I exercise 4-5 times a week. I don’t have a thyroid because of cancer nine years ago."
- Lou...
- Taken for less than 1 month
- June 4, 2023
For Weight Loss (Obesity/Overweight) "I have been on Wegovy for 2 weeks, and I take my next injection on Monday. After taking my first injection, I was sick and had nausea and vomiting, but it got better. I've lost 8 pounds, but it does make me have anxiety. I am on a low-carb diet, but I've cheated a couple of times. So far, the nausea and vomiting and the anxiety are the only side effects I've had, but I'm sure more side effects will come later."
- Lau...
- Taken for 1 to 6 months
- June 2, 2023
For Weight Loss (Obesity/Overweight) "So far, I love it. Did 0.25 mg for 4 weeks and lost 5 pounds (SW 162; GW 135). I just started the 0.5 mg injection this week. I don't have any of the negative side effects, such as nausea, vomiting, etc. Have had a little heartburn, but manageable with Pepcid AC. It has helped curb my appetite some and helps me control myself not to overeat, but it's not magic. I'm hopeful the appetite suppression will increase as my dosage increases. My only concern is that the 1.0 mg will not be available when I need it."
- Big...
- Taken for 1 to 6 months
- May 23, 2023
For Weight Loss (Obesity/Overweight) "I started Wegovy (2.4 mg) 5 months ago, weighing in at 417 lbs. Today I'm down 82 lbs. Not bad for no exercise and extreme dieting! Wegovy is NOT for the weak! My first dose almost canceled me completely out of the plan! I experienced severe nausea and vomiting the first 3 days, accompanied by fatigue. I felt horrible, but I chose to stick it out after I stepped on the scale and saw amazing results! After the first month, my vomiting stopped, however, if I ate anything that didn't agree with me, it would come up. I still experience nausea, for which I take Zofran to help keep it to a minimum. The most important thing I love about Wegovy is it makes me think about what I'm going to put in my mouth and if I'm even hungry. I have to remind myself to eat a little something, but most of the time I'm not hungry at all. Most of the time, I'll make a plate and only take a few bites, wrap it up for another time. If you are serious about losing weight, Wegovy is the way to go!"
- Wag...
- Taken for less than 1 month
- April 5, 2023
For Weight Loss (Obesity/Overweight) "I took my first shot of 0.25 five days ago. I was extremely nervous about taking it due to all of the negative side effects that I read others have had. I decided to inject in my upper thigh late on a Friday afternoon so that if I did feel sick, I had the weekend to take it easy and deal with it. The injection was painless and very easy to administer myself. I honestly noticed no side effects after taking it, other than not thinking about food as much and wanting to eat a little less. I did push the boundaries on the third evening after taking it, and I did have bad nausea, I actually vomited and felt generally ill for about 16 hours (not bad enough to not work though). I pushed the boundaries by overeating air-fried chicken wings (no sauce) that were a bit more greasy/oily than normal. Those really set me off, and I realized that I: 1. can no longer eat any type of greasy food and 2. cannot eat too much. As long as I stick to my normal healthy, low-carb diet, I feel just fine (so far)."
- Slo...
- Taken for 1 to 6 months
- April 3, 2023
For Weight Loss (Obesity/Overweight) "Starting week 9 with the second injection of 1 mg. I have lost 24 pounds in 8 weeks. The side effects happen about 3 - 4 days a week. The first weekend on 0.25 mg was the worst! I really thought I needed my last rites! I have had headaches, nausea, vomiting, and bowel issues but not like the first-week episode. I try to eat light the day of the shot and take it at night because it makes me tired. You have to stay positive and just buy meds that will help with side effects because the side effects will probably always happen a couple of days a week. Try to drink 1/2 gallon of water a day and stay away from red meat, fried food, fast food, (most) dairy and sugar. If you don't, you will feel sick from eating that stuff. Also only eating one cup of food every couple of hours has made a huge difference in the nausea. Stock up on SF ice pops and SF Gatorade. I am so grateful that I got Wegovy with my insurance and when I want to quit, I just remember how many people would love the opportunity."
- Che...
- Taken for 1 to 2 years
- September 7, 2024
For Weight Loss (Obesity/Overweight) "I sat out on a journey to lose weight in January 2023. I am a heart patient, and I was weighing 220 lbs for the first time in my life. I started in the beginning, I had lots of nausea and vomiting as I went through the different doses. It wasn’t until I got to the highest dose that I really saw the change in my body weight. The weight just slid off. I lost a total of 100 lbs. I definitely changed my diet: high protein, grilled veggies, and fruit. I will say it changed my taste buds. Salty things were overwhelming to me while on Wegovy, and so was sugar. I can’t eat cheese at all without getting sick. But I feel better. My heart is doing well, and my lipids are finally in the normal range. This medication helped save my life, and I feel so blessed. Good luck on your new journey, and don’t be afraid to ask your doctor for nausea meds, it helps a lot."
See also:
More about Wegovy (semaglutide)
- Wegovy consumer information
- Check interactions
- Compare alternatives
- Reviews (529)
- Drug images
- Latest FDA alerts (4)
- Side effects
- Dosage information
- During pregnancy
- Support group
- FDA approval history
- Drug class: GLP-1 Agonists (Incretin Mimetics)
- Breastfeeding
For Weight Loss (Obesity/Overweight) "I took 4 shots of .25 Wegovy. The first shot had no side effects and no problems. The second shot was a little different. Mild upset stomach starting about 24 hours afterward with some stomach pain. This subsided within the third day. My appetite was suppressed, felt fuller for longer. In the third shot, I had no appetite with stomach pain that lasted two days, and also felt as if I were going to pass out. I drank orange juice and ate saltine crackers with peanut butter, which helped. The last .25 shot of Wegovy… I had lost 12 pounds by this shot. But within a day, I was projectile vomiting, upset stomach, extreme pain in my abdomen, chills, and dizziness. I was taken to the emergency room. I was diagnosed with colitis that had gone to sepsis. The doctor explained a side effect from Wegovy may cause gastrointestinal problems. Wegovy attacked my colon and in turn, sepsis formed. I will not continue this shot. So many side effects go with it. It does curve your appetite, but I would be very cautious."