Wegovy and Diarrhea: What Users Say (Page 2)

• For...
• Taken for 6 months to 1 year
• May 17, 2022

For Weight Loss (Obesity/Overweight) "I started Wegovy in December 2021 at 281 lbs, and as of May 2022, I am weighing in at 246 lbs (35 lbs lost). I am on the full maintenance dose at 2.4 mg. I didn't notice many symptoms early on; however, as I got to the 1.7 & 2.4 mg, my side effect symptoms greatly increased - including vomiting, nausea, diarrhea, and a nasty burnt popcorn taste in my mouth. This medication will definitely cause you to lose weight as it completely takes away your appetite, but the combination of side effects, mostly the vomiting, makes me question if I will stay on this medication much longer. For reference, I take my medication on Saturday evening and suffer the side effects until about Thursday morning. From Sun-Wed, I find myself in/out of the bathroom throwing up when I attempt to eat the most basic of foods. I used to have a large passion for food, but I can't imagine eating some of my favorite things while these side effects take over. I would recommend for those suffering to lose weight with caution."

• Sup...
• Taken for 6 months to 1 year
• January 4, 2022

For Weight Loss (Obesity/Overweight) "Pros - I've been on Wegovy for 7 months. It started working right away. Lost between 8-15 lbs a month. It mostly has affected my appetite (not feeling hungry). Have lost 65 lbs thus far. Cons - nothing noticeable until I made it to the 1.7 mg dosage, and it got worse on the 2.4 mg. Severe diarrhea and cramps a day after eating. I noticed this became more regular after the 2.4 mg dosage. It happens 4-5 days after the injection, only for it to clear up after I give myself the next injection. Any bismuth anti-diarrhea helps to clear this, but you have to remember to take it with almost every meal."

• Eri...
• Taken for less than 1 month
• August 27, 2021

For Weight Loss (Obesity/Overweight) "Taking Wegovy for weight loss and prediabetic. Into the third week of 0.5 mg and tolerated it well so far. No severe nausea and a few bouts of diarrhea. However, I had gastric bypass a few years back, and my stomach is always off with dumping syndrome. In 18 days, I’ve lost only 4.5 lbs, and that is tracking macros and eating about 600 calories per day and keeping carbs under 80g. It definitely has taken my urge to eat away, and I have to force myself to eat. I don’t have intense fullness, as I believe due to my stomach size I already eat tiny meals like 4 ounces, so I'm not pushing my stomach and having the medicine cause me to be sick. I can tell each week the side effects do lessen. I would hang in there. I know the weight loss hasn’t been terrific, but I have to remember this could help me stave off becoming diabetic."

• Ano...
• Taken for 1 to 6 months
• May 7, 2025

For Weight Loss (Obesity/Overweight) "I have done very well with Wegovy. I am now on the highest dose. This is the 3rd week on the highest dose, and I have lost 25 lbs in 4 months, and I am still losing. I have had some common issues such as nausea, diarrhea in the first month, but that went away. Then in the 2nd month, I had minor stomach pain, and the diarrhea changed to constipation. I am still experiencing constipation but managing it with fiber. Other than these issues, I am happy with the medication, and I feel so much better!"

• Ste...
• Taken for 1 to 6 months
• March 14, 2025

For Weight Loss (Obesity/Overweight) "Been taking Wegovy for 2 months now. First month, very little side effects & lost 14 lbs. Second month, moved up to the 0.5 dose. Stomach issues started, mainly rumbling noises with diarrhea/constipation. Has gone on for weeks now (not days), so have referred myself to my GP."

• lyn...
• Taken for 1 to 6 months
• October 17, 2024

For Weight Loss (Obesity/Overweight) "Week 14, lost only 12 lbs, but improved labs. I have had uncontrollable diarrhea for 4 days now, together with very foul-smelling burps. I had no side effects until I started 1.7 mg. I may have to go back to 1 mg dose. I have more weight to lose."

• Lor...
• Taken for less than 1 month
• October 3, 2023

For Weight Loss (Obesity/Overweight) "I was prescribed Wegovy for weight loss purposes. I’m 5’11, 225 pounds, with a BMI of 31%, so I can be considered obese. I’ve been on it for one week and have lost 7 pounds. I’m starting with the lowest dosage (0.25). First of all, the injection was completely painless (for me). I also inject Humira bi-weekly, so maybe I’m just used to it, but I was shocked to feel absolutely nothing. I questioned if I was doing it right, it was so painless. Do not let some testimonials scare you! I did a lot of research while waiting for the drug to come back into stock. 90% of what I read were complaints about vomiting, diarrhea, some people getting so sick they had to go off of it. Some of these reviews were written after only a week or two of the drug usage. So far, my personal experience has been completely different than what I’ve read. That could change as I go up in dosage. As of right now, the only side effect I’m experiencing is a complete lack of appetite."

• Pnw...
• Taken for 1 to 6 months
• March 31, 2023

For Weight Loss (Obesity/Overweight) "I’m on week 5, doing the slow increase up to 2.4 mg. The first month was 0.25 mg, and this month is 0.50, next month 1 mg, etc. Learned after my first dose to do several things. Be super aware of what I eat on my dosing days and the next two days. Nothing fatty, unhealthy, etc. results in diarrhea. I always take Pepcid in the mornings now and on my dosing day, and the next couple of days take another antacid before I eat. I drink lots of water. Also, one time I pushed the pen into my skin, and it didn’t click to dispense the medication, so I lifted the pen and ended up wasting some of the medication."

• Anonymous
• Taken for 1 to 6 months
• February 13, 2022

For Weight Loss (Obesity/Overweight) "I’ve been on Wegovy for about 6 months, and I’m about done with it. I’ve been sick more times than I think I have in my entire life. It does help with weight loss and appetite suppressant, but the side effects are so bad. I’ve had week-long bouts of nausea, diarrhea, and acid reflux. I can no longer eat spicy foods or dairy. If you have a strong stomach, I recommend it, but if you don’t, good luck!"

• Jen...
• Taken for less than 1 month
• January 3, 2022

For Weight Loss (Obesity/Overweight) "I started this weight loss journey with Wegovy 4 days ago. No nausea, but definitely have some diarrhea starting the second day. I will continue with the treatment unless the side effects change or worsen."

• Bec...
• Taken for 1 to 6 months
• April 21, 2025

For Weight Loss (Obesity/Overweight) "I started at 0.25 ml mid-January 2025. After one month and no side effects, I was down 16 pounds. Second month I titrated up to 0.5 ml. No side effects and lost an additional 8 pounds. Third month titrated up to 1 ml. Three days in, I have been experiencing explosive, uncontrollable diarrhea, sulfur burps, and mild stomach cramps. Trying to control it with Pepto-Bismol and Imodium offered only a brief half-day respite, and then the diarrhea was back with a vengeance. Still losing about 2 pounds per week, but only sticking to the BRAT diet, supplementing with saltines and oatmeal. Water and Gatorade are my main sources of fluids as I am trying to stay hydrated. Decided to speak with the doctor and seek blood work and stool sampling just to make sure nothing else is going on. Depending on what comes of this, I hope to keep continuing on with this medication as it has helped me tremendously with weight loss, lowered my A1C, and boosted my self-confidence with respect to how I look and feel."

• Bec...
• Taken for 1 to 6 months
• April 21, 2025

For Weight Loss (Obesity/Overweight) "I started at 0.25 ml mid-January 2025. After one month and no side effects, I was down 16 pounds. Second month I titrated up to 0.5 ml. No side effects and lost an additional 8 pounds. Third month titrated up to 1 ml. Three days in, I have been experiencing explosive, uncontrollable diarrhea, sulfur burps, and mild stomach cramps. Trying to control it with Pepto-Bismol and Imodium offered only a brief half-day respite, and then the diarrhea was back with a vengeance. Still losing about 2 pounds per week, but only sticking to the BRAT diet, supplementing with saltines and oatmeal. Water and Gatorade are my main sources of fluids as I am trying to stay hydrated. Decided to speak with the doctor and seek blood work and stool sampling just to make sure nothing else is going on. Depending on what comes of this, I hope to keep continuing on with this medication as it has helped me tremendously with weight loss, lowered my A1C, and boosted my self-confidence with respect to how I look and feel."

• Wor...
• Taken for 6 months to 1 year
• February 25, 2025

For Weight Loss (Obesity/Overweight) "Beginning weight was 234 and began at 0.25 in June 2024, and just began 2.4 today at 177. Been going up very slowly, but weight loss has slowed way down. Still have 17 pounds to lose, but prefer 27 more. Have gone from 2XL/Size 22 to size 14. Have dealt with nausea, headaches, occasional constipation/diarrhea, depending on what I eat. Small meals, five times a day, plus drinking lots of water is key. I get extremely tired the day or two after taking the shot. I take the shot at night, hoping to be at my goal weight by the end of May 2025. 63-year-old woman and all blood work now within normal limits."

• Car...
• Taken for 1 to 6 months
• June 4, 2023

For Weight Loss (Obesity/Overweight) "In February of '23, I learned that I had a hiatal hernia where 2/3rds of my stomach was above my diaphragm. The doctor said she could operate, but it wouldn't stay fixed because of my body mass. So my primary care PA suggested Wegovy. I agreed to try it. The first 3-4 days of my first week were rather rough. I had horrible gas, diarrhea, and nausea. I could eat berries and yogurt, but not much else. Over the first 2 months, I lost 12 pounds. Then I plateaued. There also was a mix-up with getting my next 4 doses on time, so I went a couple of weeks with no doses. Most recently, we upped my dose, and now at 1.7 mg, I don't have many stomach problems, but I feel tired all the time. I get up and do a few things, and then I take a nap. And repeat. I had one time when I started to feel dizzy and faint because my blood sugar was low, but a sweet drink and a burrito helped with that. I am still slowly losing weight, which makes me happy! I've lost a total of 18 pounds in about 4 months."

• Big...
• Taken for 1 to 6 months
• July 20, 2022

For Weight Loss (Obesity/Overweight) "I used to take Saxenda until my insurance would no longer cover it. Worked great. Lost at least 50 lbs. Now I’m on Wegovy, more or less the same side effects. Diarrhea and burps that taste like rotten eggs. On Saxenda, they went away once I was up to full dose. Right now, it’s my 3rd week on full dose, and I’m still getting those side effects, just not as bad. I’m sure they’ll eventually go away. One side effect I have and can’t find listed (which is what brought me here) is my skin is sore and tender. Not unbearable, but riding in a car and hitting bumps is quite uncomfortable. Anyone else experience this?"

• Bit...
• Taken for 6 months to 1 year
• March 23, 2025

For Weight Loss (Obesity/Overweight) "I started Wegovy in April 2024. I was 193 lbs at just between 5’1”-5’2.5. I had tried everything, but food noise and the fact that being so short, the calorie intake had to be so low to lose weight. Anyway, the first thing I noticed was a bit of nausea. That went away after a few days. I have had very minimal side effects. Sometimes a little nausea, constipation, or diarrhea. Nothing to really disrupt my life. For the first time in my life, I actually can tell when I am full. My IBS has been almost non-existent. I’m more awake. I have fewer sweet cravings. The food noise is still there, but my stomach is able to signal my brain that if I eat more, I will feel sick. I have lost to date 4/2024-3/2025, 63 lbs. I am just about to hit my normal weight goal. I knew how to lose the weight. I am someone who has a very difficult time shedding the weight with exercise and diet. I am super grateful for this opportunity to prove that a drug works so well."

• Sco...
• Taken for less than 1 month
• December 28, 2024

For Cardiovascular Risk Reduction "So far, so good. I’ve been on it for 4 weeks now. I did have gas and stomach pain, nausea, and diarrhea, but that was in the beginning, and it’s lightened up a lot."

• In ...
• Taken for 1 to 6 months
• June 7, 2022

For Weight Loss (Obesity/Overweight) "6-7-2022: I am about to start my eighth week on Wegovy: first four weeks at 0.25 mg, second four weeks at 0.5 mg, and starting 1.0 mg this week if I can get the medicine. My pharmacy is having difficulty getting it. The first week was difficult. I started on a Thursday evening and had diarrhea for two days straight and accompanying upset stomach. I took Friday off from work and was sick on Saturday. On Sunday, I felt better but very tired and stayed in bed all day. I was feeling better by Monday and Tuesday. Since then, few side effects. I lost 5 lbs. the first month and 7 the second, averaging my doctor's goal of 6 lbs./week. I'm so glad to be moving in the right direction. I'm 5'2" and weighed 260 at my highest. I lost 30 pounds a couple of years before COVID hit and had kept it off (a major triumph) but had gained back 10 of those pounds before starting Wegovy."

• Anonymous
• Taken for 1 to 6 months
• May 6, 2022

For Weight Loss (Obesity/Overweight) "Ok, so it's been 2.5 months. I made it to the 1 mg dose and had to stop. I did fine with the 0.25 and 0.5 doses and lost weight. The trouble started when I hit the 1 mg dose. I felt horrible the first week, like absolute death, with side effects of nausea, diarrhea, abdominal pain-just awful. I reached out to my MD, and she said this was normal to go ahead and keep going. The second week on this hasn't been much better, with vomiting, and I'm stopping it myself. I have lost 20 lbs the last couple of months even on the lower doses, but due to supply chain issues, my pharmacy cannot get them in, so I'm having to switch medications now. Lower doses have way less side effects and are just as effective. I wish I could've continued with it."

• Hop...
• Taken for 1 to 6 months
• April 22, 2022

For Weight Loss (Obesity/Overweight) "I started on Ozempic 12 weeks ago in Jan 2022, which is the same as Wegovy in a lower dosage. I spent 4 weeks on the 0.25 dosage, losing 2 lbs. Moved up to the 0.5 dosage for 4 weeks, losing another 2 lbs, moved up to the 1 dosage for 4 weeks, and lost an additional 3 lbs. I just took my first dose of Wegovy at the 1.7 dosage, and wow can I tell a difference. I won’t lie, I have experienced a few side effects, such as constipation, some abdominal pain, nausea, headache, and diarrhea, but all have been mostly mild and very tolerable. Nothing that can’t be helped with eating a little less. The key to managing all of it is learning how to eat properly with the right portion sizes. Only eat until you are satisfied rather than full. For me, it is well worth dealing with mild side effects in order to achieve a healthy lifestyle!"

• Sli...
• Taken for 1 to 6 months
• April 1, 2022

For Weight Loss (Obesity/Overweight) "So I am 5'4" and I found myself at the weight I was when I delivered my children, 145 pounds. For three years plus, I desperately tried to approach my goal weight of 125 pounds, dieting and feeling miserable for 3 years. I told my doctor I was dieting and exercising and could not budge the scale. At 60 years of age, the weight just doesn’t come off like when you are young. I’ve been on Wegovy for 6 weeks and have lost 12 pounds-a miracle! Now at 133 pounds, I’m staying the course to my goal. I will say the nausea is the worst side effect and comes in intermittent waves. I have Zofran (ondansetron) for when I can’t take the nausea. One of the best side effects for me has been totally eradicating my diarrhea. I have irritable bowel on the diarrhea spectrum, and luckily I did not get the diarrhea side effect but more the constipation, which has totally normalized my GI tract! I am so happy about this and assume this is due to slowing gastrointestinal motility."

• Ddd...
• Taken for 1 to 6 months
• February 11, 2022

For Weight Loss (Obesity/Overweight) "I have been on this medication since August 2021. So far, I have lost 36 lbs. I have been on the max dose of 2.4 for going on 2 months now. Side effects I have experienced have been sulfur burps/gas, nausea, vomiting, diarrhea, and sensitivity on my back and scalp (sunburn-type feeling). Although I haven’t had the most pleasant side effects, I would still recommend this medication. Now that my body is used to it and I am up to the max dose, I haven’t had any of the side effects lately, besides occasional nausea. I have noticed the most weight loss on the 1.7 and 2.4 doses. Just this week alone, I have lost 5 lbs. I hope to keep losing at this rate. I am only 40 lbs away from my goal weight now. So far, I have not really changed much with my diet or exercise. I cook my meals at home, drink water, and walk a few miles a week, and that is it. If you can stick it out and get up to the maintenance dose, it gets better!"

• Me ...
• Taken for 1 to 6 months
• January 25, 2022

For Weight Loss (Obesity/Overweight) "Nausea, diarrhea, constipation, sulfur burps, fatigue, loss of appetite, super sensitive to smells, I have to make myself eat enough. It's like morning sickness, only it's 24/7. Zofran helps for about 6 hours. Cannot tolerate much besides chicken broth and Brussels sprouts. No fried, fatty, oily, spicy foods. Need to stay hydrated with water. Ginger ale helps. I'm up to a 1 mg dose and 14th week. This nausea is constant and impacts my daily routine significantly. However, it is the only effective weight loss option that's worked in 26 years of diets and exercise and eating healthy. I will not give up. The weight is killing me, and I needed this medication. I started at 221 lbs. and now I'm at 194.3 lbs. BMI is close to pre-obesity, and I know I'll cry the day I hit it. Full disclosure, I'm disabled in part due to my weight. There is no way I could have worked and taken Wegovy with the severity of my nausea and fatigue. But the mobility and breathing issues are improving."