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Quetiapine for Generalized Anxiety Disorder User Reviews (Page 5)

Brand names: Seroquel, Seroquel XR

Quetiapine has an average rating of 7.4 out of 10 from a total of 189 reviews for the off-label treatment of Generalized Anxiety Disorder. 66% of reviewers reported a positive experience, while 16% reported a negative experience.

Reviews for Quetiapine

  • Julie...
  • Taken for less than 1 month
  • July 18, 2019

"I was prescribed Seroquel 50 mg XR, one pill at bedtime to augment my antidepressant. I only took it for three nights in a row. The anxiety was unbearable after taking the medication. I slept throughout the days and forgot appointments, forgot to take other medication, forgot to eat. The only moments I could keep my eyes open I was in panic. Horrible drug."

1 / 10
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  • AVRG...
  • Taken for less than 1 month
  • November 21, 2021

"This Seroquel 25mg a day saved my life. Experiencing extreme anxiety and panic attacks to the point I lost my sanity. The neurologist administered it to me and it works like a miracle. I lost hope that time, and thought that I would be mentally ill forever but luckily after taking this drug I snapped me back to normal again. Experiencing those side effects and also aware for the danger of this drug but that's not a problem to me as long it keep me from going crazy permanently. The effect of this drug may differ to everyone because we have different case scenario. But in my experience it worked."

10 / 10
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16 Report
  • xrx44x
  • December 29, 2020

"I’ve been diagnosed with insomnia and anxiety. I’m not sure how I got on quetiapine since I’ve been on it for 5 or so years. I was hoping weight gain would be a side effect I had since in underweight but no such luck. I don’t really have any side effects from it, I take 25mg before bed. My anxiety has improved tremendously over the last 5 years, it doesn’t make me so sleepy that I have to go to sleep. It doesn’t take me hours to fall asleep anymore and I no longer wake up after sleeping for an hour or two like I did before. The only downside I’d say is if I don’t sleep more than 4-6 hours I do NOT want to get up. That’s pretty easily manageable for me, I just take it and go to bed/play on my phone for about an hour before I want/need to go to sleep. It takes about 30-45 minutes to kick in so I’m usually sleeping by the time I need to go to sleep."

10 / 10
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20 Report

Frequently asked questions

  • JND
  • February 22, 2015

"I have bipolar type 2 for 20 years now. I'm also a registered nurse. I take depakote for my mood stabilizer and lexapro and for about 6 years was on 25mg of seroquel for sleep. It put me to sleep, a very deep restful sleep, but I found come morning when it was time to wake for work I was soooooo groggy throughout the day it was awful....UNTIL when I had to come off my depakote to get pregnant and my doctor said we could increase my seroquel to take its place, that the higher the dose of seroquel 200+ the LESS daytime sleepiness I would have and I wake up feeling refreshed. Most sedating drugs the reverse is true,like for exp. Valium take a tiny dose ok but bigger doses and your asleep. Not true of seroquel. Look it up or ask ur psych"

10 / 10
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  • Karima
  • Taken for 2 to 5 years
  • April 10, 2018

"After trying every single antidepressant on offer here my GP agreed to try this. I was previously having panic attacks to the point of feeling like my throat had swollen and/or throwing up daily. I had the slow release version and it helped but I couldn't wake up! I'm now on 25mg normal one at night and my vomiting stopped within the week and I maybe have a panic attack now once every couple of months. It has been my absolute life saver."

10 / 10
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31 Report

Are you taking this medicine?

  • Anon
  • Taken for 6 months to 1 year
  • January 4, 2022

"This is an interesting medication. The first 2-4 weeks can be tricky. I found that it does have a sedative effect and was amazing for sleeping. It did also make me agitated/jumpy if I took a higher dose (weirdly paracetamol or ibuprofen lowered this effect). Can be helpful to try a lower dose and see the difference. I did feel foggy and had trouble concentrating the first month. Your body does need to get used to it, then I saw major improvements in mood and reduction in depression and anxiety. It is good because it immediately reduces extreme anxiety (compared to SSRIs and SNRIs) and then kicks in to help over the longer time. I would use in conjunction with working with a psychologist. If you're going through anxiety or depression this medication is a much better option to benzos or SSRIs or SNRIs."

9 / 10
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  • derek...
  • Taken for 1 to 2 years
  • October 28, 2015

"I have been using these about a year or so. I take 300 mg atnight , I never used to sleep or if i didi it was very little, I used to pray for a few hours sleep , since using these I sleep anywhere from 8 hours to as long as I want to , makes me able to handle life a lot better, good luck and take care"

10 / 10
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  • Januscl
  • October 29, 2017

"This drug is surprisingly risky to take. While it certainly does have a significant effect in terms of reducing tension, anxiety and overthinking and sleep problems, it certainly has some really unpleasant side-effects. For instance it’s extremely sedating, it shuts down the emotional system making it almost impossible to feel any feelings except extreme tiredness and irritability. Not the type of drug I’d recommend anybody, but definitely the drug I’d warn people against taking."

2 / 10
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  • clarkee
  • Taken for less than 1 month
  • February 21, 2023

Seroquel (quetiapine) "I just started taking Seroquel 25mg for generalized anxiety disorder, OCD, and panic attacks which have been going on for nearly 25 years and now I'm 65 years old. On the first night, I broke the tablets up in quarters and took 6.25mg at about 7 pm, waited 2 hours, and took another 6.25mg so this will gradually enter my system because I do not get along with antidepressants at all. If all goes well then I will bump it up another 12.5mg the second week. I'm to revisit my nurse practitioner on Mar 20 to give her the low down. In the meantime, all I take for anxiety is clonazepam 0.5mg daily as needed. This will work well with Seroquel because if I start feeling panicky then I'll take clonazepam to hopefully offset it. I will put up another review in 4 weeks on my progress with this medication."

3 / 10
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  • Evieh...
  • Taken for less than 1 month
  • October 10, 2018

"Thank you for all the positive comments. They have really helped and given me hope. Can I ask roughly how long it took for you to feel an improvement. I have OCD, GAD and low mood. I’ve just gone over two weeks at 50mg at night. Feel very sleepy and eating a lot. Just scared as my Psychiatrist is weaning me off Prozac and Pregabalin so I will just be on Quetiapine. Last time I was on nothing my OCD was so severe I just wanted to end it all. Thank you x"

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  • CHml
  • Taken for 6 months to 1 year
  • August 7, 2023

"1/4 or 1/2 of 25mg works well for me to fall asleep, no more overthinking at night and no anxiety in the mornings. It's a little harder to wake up but I feel sooooo relaxed and zen for all day long. So it is a good solution for me."

9 / 10
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  • Marcus
  • December 27, 2018

"I have had episodes of extreme anxiety/depression, but on my third episode I was under constant stress at work so could not heal naturally. There fore I was put on SSRI's and benzo's but they did nothing. Then I was put on Avanza which worked for a month then suddenly stopped. Then I got a thyroid problem and I was in a bad way so they put me on Seroquel 300mg with a month off work. It worked fine, I felt good so went back to work and then I relapsed again. I ended up in hospital and they finally diagnosed me with bipolar spectrum disorder after I explained some strange sensations I had experienced, mainly extreme irritability, followed by an inability to get out of bed etc. I am stable and the Seroquel has definitely helped but it does have side effects like weight gain, mental and physical slowness, being dumbed down and the ability to sleep all day unless I have a reason to get up like work. I have started to reduce the dose from 300mg to 250mg and already notice feeling less drugged."

5 / 10
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26 Report
  • templ...
  • Taken for less than 1 month
  • July 22, 2015

"I am going on this drug with the dose of 12,5 mg and it is so effective for sleeping. My purpose for taking this drug is insomnia. I just cut the 25 mg tablet into two halves.Side effect of feeling sedation is proiminent for me the next day, I hope I can get used to this effect in a short period."

9 / 10
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35 Report
  • Z Box
  • Taken for 2 to 5 years
  • April 26, 2015

"Helped me sleep, when even benzos and ambien didn't. Also helps with my lack of appetite. I did gain 45lbs the first few months, but eventually I lost the weight. I actually liked the weight gain, I've been underweight my whole life. As far as anxiety, I'd say it helps me relax but doesn't slow my mind down like the Xanax I used to take. Still, mildly effective for anxiety. Download card from website, 30 day supply w no insurance will cost $11, without card, $77. Big difference."

10 / 10
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  • Mark
  • Taken for less than 1 month
  • August 30, 2018

"I don't think this drug is great for panic i'm not sure it should be taken by anyone. When I took my first dose I woke up on the floor in my hallway I have no idea how I made it downstairs last thing I recall I was gong to have a snack before bed, This is a bad drug......there are better drugs for panic disorder...."

1 / 10
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  • Patch...
  • Taken for less than 1 month
  • September 2, 2017

"I've been prescribed 25mg seroquel to replace the Valium I take as when required for anxiety & panic attacks. STRONG WARNING IF U HAVE YOUNG KIDS. Don't take it for the first time if U R the ONLY parent around at the time. I wasn't warned by my Psychaitrist & luckily my partner was home when I decided to take it as it completely wiped me out. I passed out within 40 mins of taking it & didn't wake up for 14 hours. I woke up feeling like a zombie. Coffee helped a little. I've taken it 3 times so far. Maybe/hopefully the tingling feeling after taking it & then passing out will subside over time. Otherwise yes, it does help subside anxiety. I'm just not sure if that's because its forced me to sleep & then I'm brain fogged. Will update later."

5 / 10
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27 Report
  • Sarah
  • Taken for 2 to 5 years
  • October 25, 2021

"I’ve been taking quetiapine for 3+ years and it has literally saved my life. Living with undiagnosed GAD until I was 42 years old and then finally diagnosed and put on medication changed my life for the better. I was initially on a high dose (300mg XR) and over a period of 2 years plus 60mg Aropax I reduced to 100mg IR and stopped using Aropax. I did gain a lot of weight (15kg) but I have managed to lose it all after reducing my meds to just 100mg seroquel. So you can lose weight so long as you exercise daily and limit alcohol. I highly recommend this medication as it has worked perfectly for me and enabled me to maintain a highly stressful and well paid job."

10 / 10
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  • ShanW...
  • October 30, 2018

"I began on 12.5mg as I am small and didn’t tolerate other medications well. I have Generalised anxiety disorder along with depression because the anxiety and all effects from SSRIs. So yeah first week or two great! My suicidal thoughts stopped. I seemed happy again. Well that wore off after two weeks so My doc upped my dose to 12.5 on a morning and 12.5 on a night. Okay now this is where it started I began to question who my daughter is. What life is I began to become disconnected and distant. Not only that I then instead of having thoughts to kill my self I began to constantly be afraid of death afraid I would kill my self. So then I came off them and wow. Brutal. I am now on Amitriptyline which is still doing nothing. I’m holding in I know there is hope! I know this is not my fault and is not forever. Will be going back to doc for a different SSRI and never again will I touch Seroquel. Since I am still disconnected and dissociative."

2 / 10
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23 Report
  • buddy...
  • Taken for less than 1 month
  • April 7, 2017

"OMG i cannot believe my "psychiatrist" had prescribed me this med at first I was ok I thought it made me feel tired enough to sleep after about an hour and she also let me still be on lorazapam because I was already taking that for my anxiety. Well I have been on these pills 25 mg two times a day for about a month. And I have gained almost 20lbs and when I try to sleep my legs go crazy. I have been having severe restless leg. and I mean my legs would kick hard when I am trying to sleep. So last night my man was trying to keep me calm and tell me it will be ok and he told me to look up the med and the side effects. I am now in tears after reading all the bad effects and its isn't good for anxiety ADHD & mood disorders I hate dr's who know nada."

2 / 10
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  • Terry...
  • March 31, 2016

"I've been on celexa for about 18 months to help ease overall anxiety I take 30 mg daily and about 10 months ago have been put on seroquel also I take 25mg morning and night. And find that if I stay active and eat healthy I feel fine no anxiety I can handle everything much better. However some days 50 mg daily isn't enough and I take an extra 25mg as needed at night. Only side effects I've noticed is insatiable hunger and craving for sweets. Also gained about 9 kilos in the 10 months apart from that I find seroquel to be very helpful at treating the racing thoughts and shortness of breathe"

8 / 10
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  • Mindf...
  • Taken for 10 years or more
  • May 9, 2023

"I have been taking quetiapine on and off for years. I have to say that the drug makes you feel great. I have been taking various doses over the years also because of different life events and tolerances built up. I can sometimes go without taking it for some length of time but I find that when anxiety gets you down, this drug is amazing at making you feel calm and relaxed. I suffer from quite bad anxiety and this drug takes away all that worry. It does makes you extremely hungry and I now have a large stomach haha. But it’s great. I currently take 6.25mg and just enough to get you to sleep and feel chill. At higher doses you can feel tired and groggy the next day which is no good for work. Anyway I approve this drug."

8 / 10
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  • Anonymous
  • March 31, 2016

"I began with 25mg Seriquel last night. I am taking TARVs dolutegravir plus boosters. I woke up for the first time in months without anxiety, although I did not sleep more than 6 hours. Perhaps I have to increase the dose."

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  • GADdi...
  • April 20, 2016

"First I was on instant release Seroquel which helped somewhat at 50-100 mg doses. It gave me tachycardia so I switched to XR version. Been now at 200 mg and my anxiety has improved. Little bit foggy and sedated sometimes. Will try to lower the dose to 150 mg and see if it helps."

9 / 10
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  • Virgi...
  • Taken for less than 1 month
  • June 19, 2017

"I just started taking 100mg quetiapine to help me sleep. Only been on it 5 days. I suffer from anxiety-sometimes severe, depression-sometimes severe & severe pain from severe osteoarthritis, severe back pain from multiple surgeries & degenerate disc disease. Anyway, thus far quetiapine seems to help me sleep somewhat. Still waking up too early, average 4 hours sleep per night & I feel real foggy. Not sure what to do cause I was taking trazadon which helped me sleep but nasty stuff. So from a lot of reviews I've read here it seems quetiapine affects a lot of people differently. I'm so scared of it yet I'm exhausted from lack of sleep which causes me more anxiety & depression. I've not gotten a decent night's sleep in months. Any suggestions?"

5 / 10
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  • Georgia...
  • Taken for 1 to 2 years
  • November 16, 2014

"I live in New Zealand. I took less tan 25mg once a night (I'd break it in half, sometimes even quarters) and it helped me sleep, reduced anxiety, and helped stabilize my mood. I took this with 40mg of fluoxetine. I've returned to taking it with 225mg of venlafaxine a few times to ease anxiety when needed. After about 12 months of taking it, I began to feel very lethargic, and generally slow, and my short term memory basically stopped existing. I had to stop taking it then. I wish it were available to 12.5mg tablets. My main issue was having to take more than needed due to the tablet size."

9 / 10
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29 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.