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Quetiapine for Generalized Anxiety Disorder User Reviews (Page 3)

Brand names: Seroquel, Seroquel XR

Quetiapine has an average rating of 7.4 out of 10 from a total of 190 reviews for the off-label treatment of Generalized Anxiety Disorder. 66% of reviewers reported a positive experience, while 16% reported a negative experience.

Reviews for Quetiapine

  • K p
  • February 8, 2016

"Seroquel has changed my life so much. The only regret I have about taking it is that I didn't take it much earlier in life. I used to be a very anxious, shy girl. Now people describe me as outgoing, life of the party. I no longer feel afraid of people and I don't have panic attacks like I used to. The only side effect I experienced was a 30 pound weight gain within a year (which is unusual on a low dose of 150mg per day). My dr. had added topamax to curb my appetite and it is working. Overall, I love seroquel."

10 / 10
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  • Ms Br...
  • July 5, 2011

Seroquel (quetiapine) "I've been using Seroquel now for 4 years. I suffer with anxiety and can't sleep at night. Seroquel has helped me sleep and helps me throughout the day with my anxiety, if I feel anxious I take a 25mg and it alleviates the anxiety for me. I think it's very good for both. It has helped me tremendously."

9 / 10
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99 Report
  • Dizzy...
  • Taken for 5 to 10 years
  • July 16, 2019

"I've been taking quetiapine for 10 years. 10 years ago I didn't notice any difference, only physically these tablets gave me a stomach ulcer over night, but mentally I never noticed a difference. Back in March 2019 I stopped using quetiapine and for 3 months I was a wreck I can't describe how I was . After trying 3 months off quetiapine I ended up so scared and paranoid I was convinced a neighbour was plotting to take me down. Anyway I chose to go back on quetiapine and the difference in only 48 hours was so shocking . I now know this drug a miracle for me it's just a shame it upset my stomach to the point I can no longer smoke cigs or vape. My dose is 600mg for borderline personality disorder and anxiety disorders."

10 / 10
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47 Report

Frequently asked questions

  • Lilac
  • Taken for 1 to 6 months
  • July 31, 2023

"After a lifetime of depression, anxiety, and mood swings, this medication has finally been a godsend. I’ve tried many antidepressants and a number of antipsychotics, but quetiapine is the only medication to calm me enough to be able to think clearly and make non-emotional choices. I take half a tablet (a tablet is 25mg) in the morning, half a tablet at midday, and a whole tablet at night. I don’t feel tired on it, just calm - it’s like my brain is clear of emotions so I can think without reacting."

10 / 10
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  • Cor
  • Taken for 1 to 2 years
  • July 23, 2013

"I sleep much better with Seroquel. I have anxiety and sleep like a baby. I take 25mg and find myself clear headed, calmer and refreshed in the morning. I read about the side effects and am concerned, although do not experience the weight gain. I watch how much I eat and may get some water retention from it but that is it. My weight has only gained a few pounds, if any. I do worry about eye problems. I had my first experience with an ocular migraine a few months ago and wondering if that is related to this medicine."

9 / 10
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Are you taking this medicine?

  • Carlos
  • Taken for 2 to 5 years
  • October 29, 2018

"I have found quetiapine to be immensely effective in managing my anxiety. I take a 25mg every night before bed so it helps me sleep (especially when I can't seem to turn my brain off!). I tried going without it for a while as I was trying to lose weight and my doctor said the quetiapine likely contributed to my weight gain. I only lasted about 10 days without it. My anxiety was unmanageable and I wasn't sleeping. Other than weight gain, I haven't had any adverse side effects."

9 / 10
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  • thewa...
  • September 21, 2017

"I was prescribed 25 mg to be taken as needed for anxiety. The first time I took it I only took half a pill as suggested by my doctor, this knocked me out. I switched to 1/4 tablet and take it as needed before bed. I have taken the medication like this for 6+ years now and have had no problems, I have seen a significant decrease in my anxiety, and have elevated mood or affect the day after taking it, with the only side effect being grogginess. I was taking Klonopin before this but hated how addictive it was. I have intermittent severe anxiety with paranoia and occasional auditory hallucinations, mania, and depression all of which is helped by even the super low dose of Seroquel."

8 / 10
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  • Silly...
  • November 14, 2016

"I take 600mg at night, the XR slow release version made me very dizzy, so I take the immediate release version. Anxiety is completely gone, I sleep well, and along with the Effexor SSRI I'm back to my normal happy self. It saved my life"

10 / 10
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  • Anonymous
  • Taken for less than 1 month
  • November 27, 2019

"I sleep much better now I'm on quetiapine I feel calmer and my mind ain't race in as much I take 100mg at night to sleep fill very drowsy when I wake and my knees fill like jelly but I am grate full for good nights sleep"

8 / 10
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41 Report
  • May...
  • Taken for 2 to 5 years
  • August 2, 2018

"Have used this drug for 4 years, in combination with lorazepam for panic attacks and anxiety which was causing me not to sleep. Started at 25 mg, after one week went down to 12.5 mg. as found I needed approx. 10 hrs. sleep or was groggy in the mornings. Am now off the lorazepam but still take 6 mg quetiapine (1/4 of a pill) to sleep. I have tried to come off it completely but find my mind won't calm down and enable me to get to sleep without it. My doctor says that at such a low dosage it's likely more a placebo effect. But it works for me and I get a good 8 hrs sleep and feel rested. As I am 68 yrs old I have no problem staying on it for life. I have not experienced any side effects and in fact have lost weight."

9 / 10
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  • Vanessa...
  • Taken for less than 1 month
  • August 30, 2022

"I have GAD since I was 16 years old and tried many IRRS like Paroxetine. I've been on Lexapro 20 mg for over 12 years and feeling good in general, but since I am approaching my menopause (I am 48 yo now) I started to feel very high anxiety levels (I was about taking my life) and started Seroquel for a few days. I am, slowly, feeling like me again. This medicine saved my life, so far."

9 / 10
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  • Frazz...
  • Taken for 6 months to 1 year
  • June 5, 2017

"I've been on seroquel XR 50mg for the past 8 months for Generalised Anxiety Disorder and intrusive racing thoughts. Only take it in the evening before bedtime. This helps me sleep through the night and not wake up in the middle of the night with panic/anxiety issues! It is somewhat sedating, and do have issues waking up in the morning, but coffee helps. I didn't gain any weight on it as it helps me get going during the day on things that would usually drive me into a panic situation! I actually enjoy going out for walks and socialising now as opposed to being apprehensive and terrified of (insert intrusive thoughts)! Needs some adjustments occasionally; on weeks I'm doing well I only take half of the 50mg dose and do Ok."

8 / 10
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  • Averis
  • Taken for 1 to 2 years
  • December 5, 2015

"This drug has been a life saver from my anxiety and insomnia. Maybe there's a few minor side effects drowsiness being the worst but I take 25mg at night and can finally sleep, the first couple days were pretty rough heart pounding and felt like a zombie but as time goes on that seems to be subsiding I have a bit of an eating disorder and serequel helps me with eating I don't mind gaining a few pounds on this drug considering I was a 110 pound 20 year old man this drug saved me life took me out of a deep depression stage and helped with my anxiety, other drugs I tried and didn't work, ativan, xanax, clonazepam, clorazapate, Valium, buspar, nozinan, zoloft, mirtazapine (don't ever take this drug gave me seizures), prozac, and many others serequel has worked wonders for me"

10 / 10
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  • Bev
  • Taken for 5 to 10 years
  • April 16, 2018

"8 years ago I had a pyschotic episode which resulted in being sectioned under the mental health act 1983 (UK) . I don't have a mental health condition. Back in the day you would say I had a break down but it's actually recored as an acute pyschotic episode. It has taken me a long time to get back to who I was but now that I am on a dose of 50mg. I don't over think things anymore. If your doc has prescribed these for pyschotic symptoms I would try and bear with it. After first the side effect are quite bad. I was on 300mg in hospital and for a couple of years after. Its only been in the last year I have been able to reduce them. In the 8 years I have been taking this medication I've tried to reduce it several times but became unwell again. I know my signs of becoming unwell ,I always seek help and supervision from doctors or mental health. I'm now on 50mg so it can be done. I hope this helps anyone in similar circumstances."

10 / 10
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  • 09dib...
  • Taken for 6 months to 1 year
  • October 31, 2017

"I have anxiety/phobias/social phobias/panic attacks/stress/anxiety/generala anxiety disorder. Seroquel was one of the best medicines ever I got for my heavy panic attacks and anxiety etc. Seroquel stabilized me very well in all of my problems and I continue to taking it for 6 months. One of the best antipsychotic drugs out there. I recommend it to you. Also it cause anxiolytic and sleep effects which I would like it when you can't sleep much."

10 / 10
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  • Anonymous
  • August 19, 2016

"I have been dealing with undiagnosed depression and anxiety for the last year or so, and a few weeks ago I was finally diagnosed with both, and I was prescribed 50mg of Zoloft, initially, and then 100mg eventually. While the Zoloft was helping with my depression, it made me unbearably anxious. My dosage was lowered to 75mg and I was prescribed Seroquel as well. The combination of both has been very successful. I feel no sadness or anxiety currently, and I take 12.5mg each of Seroquel in the morning and the evening. I'm a little slow and lethargic, but otherwise have had no side effects, and the lethargy is usually solved by a 30-minute nap. In low doses, I highly recommend this drug."

8 / 10
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  • Jabba
  • Taken for 1 to 6 months
  • October 30, 2023

"Adult female, taking this medicine off-label for Generalized Anxiety Disorder, for CPTSD from severe traumatic events I experienced in my childhood and throughout most of my adult life (sexual violence), and for ADHD. It helps me sleep and gets rid of repetitive and recurring thoughts as well as extreme emotions I deal with daily, enough to help me focus on other tasks. I’m less argumentative, not emotionally numb but less affected by what others say and do, and able to see things as they are. Highly recommend. It’s not addictive and the benefits outweigh the side effects for me at 25 mg. Side effects include bloating, constipation and fatigue but eating healthy and exercise helps. I also have low appetite. Previously was prescribed SSRIs (escitalopram, sertraline) and benzos (Klonopin, Xanax) by other docs, which made my anxiety much worse, and not better. Quetiapine is a good alternative for me."

9 / 10
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  • Darcyb
  • July 16, 2014

"I've been taking quetiapine 25mg day and night for about a month now. I find it is great for taking away anxiety, but I am so so tired could sleep the clock round. I'm also on 20 mg Cipralex for depression. I have no energy to do anything. "

7 / 10
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  • Chehack
  • Taken for less than 1 month
  • November 18, 2019

"I have been on ciplar 120 but it didn’t work on my anxiety and then also paxil 12.5 which didn’t work either.But because I have bipolar and have manic episodes doctor could not give optimum Paxil dosage for anxiety as it could make me high Qutan 25 mg twice a day works on anxiety in a beautiful way feeling positive, calming and relaxing and reducing anxiety 80-90%.. higher dosage ie 25 mg thrice a day makes me too sleepy. It also works well on my mood stabilising and balances both depression and mania . Plus it’s a feel good medicine"

9 / 10
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  • Anon
  • January 3, 2016

"Last year I was put on Effexor for anxiety and ended up becoming manic. The doctor in the ER put me on this and Epival to stop the rapid cycling mania. Now that I have it under control, they removed the Epival but kept me on this for my extreme anxiety. I take 600mgs at night, it is a pretty high dose, but the higher the dose with this med , the less sedating it is believe it or not. It has been a life saver, yes, the first month was tough, I would wake up slurring my words and very confused, but now after 5 months it works great. I have no gained much weight from it, around 15lbs, which I needed as I was severely underweight . I am very happy with this medication, it calms my ADD and my anxiety."

9 / 10
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  • Sweet...
  • March 27, 2017

"Seroquel is like the silver bullet. It not only relieved me of my anxiety, it also makes me feel positive, serene and generally in a good mood! I am on 125 mg at night. I was on 100mg but went off to try Risperidone ( to try to help with the weight gain). Risperidone was not nearly as effective for me as Seroquel so I went back on but 100 mg wasn't enough so I upped it to 125mg and I am back to feeling great! I have had weight gain but I feel so much better being on Serequel. My doctor recommended I cut out carbs and sugar. When I did cut out carbs and sugar I did loose weight but it is difficult for me to stick with."

10 / 10
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  • Wisal
  • June 5, 2019

"I have used a lot of medicines but the quetiapine worked for me comparatively . I took this drug for 6 months ,my sleep was great, my energy was good , and most disturbing thing panic attacks are silent now because of this. I left this drug due to causing long term effects but it helped me in my panic disorder . At first it given me full blown panic but after a week it settled down and now I was enjoying it."

9 / 10
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36 Report
  • Megat...
  • Taken for 6 months to 1 year
  • November 28, 2015

"Great drug 400 time release I have been house bound for several years with anxiety I have been taking this for nearly a year at the start a lot of side effects they went after a month so stick with it it will get better. I can now lead a normal life this drug as saved my life and given me hope for the future thanks quitieapin"

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  • Lamrim
  • Taken for 1 to 6 months
  • May 12, 2023

"I was prescribed this medication in early sobriety from alcohol and it helped tremendously with the insomnia, anxiety, and generally crazy busy thoughts that cannot be shut off once the brain has stopped receiving its alcohol, yet hasn't yet compensated naturally with the right chemistry. It slowed me down, calmed me down, and allowed me to sleep deeply and fully in a time where for a week or two there's just no such thing as sleep for many people who decide to get sober. I've been to detox. They load you full of Valium for a week then cut you loose. They might as well just be serving cocktails. Quetiapine gave me the relief I needed from the difficult symptoms of early sobriety and the jump start into a much healthier life."

10 / 10
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  • Oodle...
  • Taken for 1 to 6 months
  • November 28, 2015

"I'm a 25yr old woman who is recovering from a hysterectomy and my psychiatrist prescribed Seroquel- 50mg at night to help me cope with my GAD before and after my hysterectomy. So far, it's helped significantly with my GAD and PTSD. It is quite sedating but it's nothing too intense. More so relaxing and definitely helpful since falling asleep was an issue. Now, I sleep through most nights! I've read some reviews and some people have had terrible luck with this drug. My rule of thumb is always talk with your doctor and seriously weigh the side effects with your long term quality of life. Some drugs don't always mix well with certain people but only you could know that and make that call. For me, this drug is worth its weight in gold!"

9 / 10
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54 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.