Promethazine User Reviews & Ratings (Page 4)

• jal...
• February 24, 2010

Promethazine for Motion Sickness "My husband and I have used Dramamine in the past for motion sickness while on our fishing boat. A 50 mg tablet will put us to sleep within 3 hrs after taking the pill. One time I could not drive home, I was falling asleep at the wheel. I went home and could not keep my eyes open. This time during our cruise, we saw a pharmacist on an island stop, and she gave us Phenergan and told us to take 1 15 mins. before going on a fishing charter. The pills worked wonderfully! We were out in really rough waters on a 30 ft. fishing boat for 4 hrs. Did not even get queasy at all! We were not even tired upon our return either. As a matter of fact, my husband said the pill made him hungry, and he ate more. Phenergan is wonderful! Throw away the Dramamine!"

• Yat...
• Taken for 5 to 10 years
• February 8, 2019

For Sedation "Being an insomniac on and off (maybe once or twice a week as needed) for as long as I can remember, I find the only thing that really helps is promethazine. It doesn't make me feel nauseous the next day like a lot of other sleeping tablets, both OTC and script. It can take a few hours to work, so I need to take it at least a couple of hours before I want to go to sleep. There is one negative - nightmares. I haven't heard from many other people who have experienced the same thing, but let me tell you, they can be horrendous - the worst kind of terror you can imagine. The weird thing is, sometimes I get them, sometimes I don't! And the half-life is 12-16 hours or something, so you can be quite fatigued the next day. Overall though, in spite of all it, it's a winner for me."

• Emm...
• October 5, 2016

For Nausea/Vomiting "I have HG, and I've thrown up almost every hour in the hour. I was hospitalized twice before they finally gave me Promethazine. I wasn't able to keep down the oral medication, but I opted finally for the suppositories, and while it takes about 30 minutes for me to feel completely better, it's truly a lifesaver."

• Sza...
• November 28, 2011

Promethazine for Nausea/Vomiting "I had gallbladder surgery and got narcotics for pain afterwards. No matter what painkiller I got, they made me vomit even at half the dose. Ondansetron (Zofran) helped some but not fully. Once I got my first dose of Phenergan, my nausea was completely gone. It made me very sleepy, but I was very happy about it. This was the best anti-nausea medication that I ever had!"

• Its...
• Taken for 2 to 5 years
• May 22, 2017

For Nausea/Vomiting "I was first given this medication after being admitted to the ER with a kidney infection, it is a literal miracle. I have an intense phobia of vomiting, which gives me horrible anxiety anytime I feel nauseous (which is often with acid reflux and IBS), which makes the entire situation so much worse, but promethazine is an almost instant lifesaver. It did make me drowsy when I first started taking it, but that has lessened as time has gone by. It does take a while to completely work (30-60 mins depending on how amped up I am from anxiety), but as soon as I take it, I know it's going to help, and I am able to calm down and let it go to work. I can't imagine going back to a life where I missed out on work and events because of nausea."

• Swe...
• November 19, 2014

For Nausea/Vomiting "I only take promethazine when I'm severely nauseous to the point where I can't unclench my teeth. And let me tell you right now that this pill is magical. After half an hour, the nausea is completely gone. But I've never gotten sleepy with it. I've actually had no side effects."

• vol...
• Taken for 1 to 2 years
• March 6, 2017

For Nausea/Vomiting "I suffer from stomach ulcers and a ton of other stomach problems, and I also have crippling anxiety and depression, so I stay nauseated most of the time. It also doesn't help that I have a fear of vomiting. When my dad was still alive (he had cancer), he told me to try promethazine, so when I went to the doctor, I asked him about it, and he told me that it would be a good medication for me. It does make me a bit drowsy, but I don't mind since I have insomnia anyway. This medication has made my life so much better, I don't know what I'd do without it!"

• Man...
• Taken for 1 to 2 years
• August 6, 2018

For Opiate Adjunct "After fracturing my clavicle in six places in a football scrum, I have suffered chronic pain. One of the fractures (where bone is no longer present) never repaired itself. I am currently on Oxycodone 20 mg four times a day, Codeine 60 mg four times a day, and Lyrica (Pregabalin) 300 mg twice a day. I was told by my Specialist to go to the chemist and get a box of Promethazine and take 25 mg-50 mg four times a day to see if it potentiated my analgesia. My goodness, has it been a life changer. I am almost at a pain score of 0. Also, given that it is an antihistamine, it removes the itch associated with opiate use. A solid 10/10."

• Rae...
• Taken for 2 to 5 years
• November 23, 2019

For Nausea/Vomiting "I love promethazine. It works for me every time. I prefer to take 12.5 mg, as the 25 mg makes me sleep for darn near 13-15 hours every time, no matter how often I take them! I usually break my 25 in half if my doctor prescribes them instead of 12.5. I have been on this medication for 3 years, and hopefully my body never builds up a tolerance to it. Works so well for my Crohn's symptoms."

• Met...
• Taken for 2 to 5 years
• April 8, 2015

For Nausea/Vomiting "Promethazine is a godsend to me. I'm on many other medications, which get me sick every morning, feeling nausea/vomiting, dizziness, etc. Promethazine takes all that away from me, and I love it! I really recommend this drug for people who get morning sickness or are RX'd a strong narcotic (Oxycodone, Morphine, Methadone, etc.), it helps and takes away the bad side effects of the narcotic. It's RX'd as an opiate adjunct. Works wonders."

• Kez...
• Taken for 1 to 6 months
• June 19, 2018

For Sedation "Having suffered a torn cruciate ligament these couple of months, I've found Phenergan to be a good sedative. I'm a bit worried about long-term use, if anyone can help. I've been taking 25mg for the last 8 weeks to aid sleep. Any information would be greatly appreciated."

• Mom...
• February 15, 2017

Promethazine for Nausea/Vomiting "I do not know what I would do without promethazine! It helps a lot with my nausea, which is very severe every day. It does not take it all away, I know, but it does help me enough. I have been using this medicine for 11 years via IV centerline."

• n8x...
• April 10, 2013

Promethazine for Nausea/Vomiting "Woke up with dizziness and terrible nausea. After 5 hours of dry heaving, went to doctor. One injection and nausea gone almost immediately. Slept for 3 hours, then ate dry bagel, chicken soup without any problems. Next day, eating normally but feel tired and a little 'under the weather'."

• Nk2...
• Taken for 1 to 6 months
• January 26, 2020

For Sedation "They work great for me to get me to sleep. Drowsy within half an hour and asleep within an hour. Can't take them every day though as the grogginess and lethargy the next day is extreme. I'm so drowsy, feel weak, and have a really dry mouth from them. I use them to treat insomnia that my depression meds cause."

• Lit...
• March 30, 2012

Promethazine for Nausea/Vomiting "I have been using Phenergan to treat nausea for years. I have frequent and severe nausea associated with abdominal pain. It has been over three years, and I am yet to get a diagnosis. I am grateful for this medicine. It is the only thing that stops the nausea. I would be crazy without this medicine! I was given Phenergan in the ER after I had a bad reaction to Zofran. It worked so well, I asked the doctor to send me home with a prescription for it. At my last ER visit, they told me they were out of Phenergan and that it was in short supply. I was given Bentyl instead. That also gave me a bad reaction. I do without nausea medicine in the hospital if they do not have Phenergan."

• Meg...
• Taken for less than 1 month
• October 12, 2020

For Sedation "Horrible: Did its job for sedation but knocked me out for 16 hours after I had already had a full night's sleep. I ended up going to the hospital because it was such an adverse effect, my neighbors couldn't wake me up properly when they came to check on me. I couldn't hear them calling me. The hospital added it to my allergy list. A few days after, I started having extremely strong panic attacks. I had never had them before and put it down to Phenergan. I've read other reviews mentioning increased anxiety after taking it. It doesn't work for everybody."

• MMK...
• December 2, 2019

For Sedation "I’ve been familiar with promethazine since I was a baby (now 27). Nowadays, I work 1-3 x 12-hour overnight shifts per week and suffer terrible allergies. Before going on Dymista for my hay fever, I would take 10-25 mg of Phenergan each night (or day depending on if I’m working) with a 2 mg SR melatonin, and to be honest, after a week of continuous use, the Phenergan no longer sedates me (down-regulated receptors I think?). However, if I take a break from it, one 10 mg will knock me out in an hour. I sleep deeply and feel groggy the next day. It also helps my anxiety and the nausea I sometimes get with melatonin. However, there are side effects: headaches, fatigue, and because it relaxes the muscles in sleep, mild sleep apnea. I sometimes wake from dreams, gagging/dry retching, or gasping for air. I also suffer from VCD and find I’m more susceptible to attacks when regularly taking Phenergan. I read somewhere that neuroleptic drugs can do this. So now I take it if needed."

• Anonymous
• June 30, 2010

Promethazine for Nausea/Vomiting "This drug is truly amazing! Nobody can figure out why I've been so nauseated and vomiting the last 2 years. When I have a really bad episode, I take promethazine and don't throw up or feel nearly as sick. I don't even get the sleepy side effect, it just makes everything better."

• Ben...
• Taken for 10 years or more
• October 28, 2023

For Nausea/Vomiting "Whenever I feel nauseous, I take one 25mg promethazine tablet. Works every time and there are no side effects that accompany this medication. Usually, the nausea is brought on by a headache or when I'm having postnasal drip. It's much more effective than Zofran. I would definitely recommend it for the symptoms I've mentioned, but mainly nausea. It works every time."

• bar...
• Taken for less than 1 month
• May 30, 2021

For Nausea/Vomiting "I am pregnant, and my doctor prescribed me promethazine for the nausea. I was a little apprehensive to take it because taking any medication while pregnant can be risky, I feel. Anyway, my nausea was so bad one day I decided to take one, and it totally wiped me out. I was exhausted and could have slept forever. At first, I didn't want to take it again, but the next day I noticed my anxiety was calmer. I have severe PTSD and anxiety, and upon finding out I was pregnant, I stopped taking my meds for it (Klonopin). They aren't safe, but I had been miserable since stopping. I just lived in complete panic/fear. I realized when I take just 1/4 of the promethazine tab my doc prescribed me for nausea, my panic attack subsides, and I can function a bit more normally. I only do this when I absolutely need it, but it's a relief to me knowing that if I do panic I can at least take something to calm me down that my doctor approves of and is said to be safe for pregnant women."

• Dee...
• Taken for 6 months to 1 year
• April 11, 2021

For Nausea/Vomiting "I went to the ER with severe nausea and anxiety. Usually, IV Zofran works when I have a bout, but not this time. So the doctor tried Compazine, which did not work either. I was then admitted that evening, and one of the residents felt that I should be given 25 mg of promethazine. It took away the nausea completely, and I was able to sleep. They sent me home the next day with a prescription, but I found that taking a whole 25 mg pill knocked me out, and I was groggy the whole day. I tried taking half, but was still groggy. So now when I get nauseous, I take only a quarter, and it takes away the nausea without that zombie feeling."

• Pro...
• Taken for 1 to 2 years
• March 12, 2016

For Nausea/Vomiting "I have had stomach issues due to my GERD and have tried Zofran, and it didn't work at all. My DR then had me try out Promethazine for whenever I feel nauseous when my GERD acts up or I eat something that makes me feel sick, and it's gone within 15-20 minutes. It hasn't made me tired, but sometimes I will get a very quick blurred vision spell, which I was warned about. But I love it, it really helps me out."

• Scr...
• Taken for 2 to 5 years
• March 4, 2015

For Sedation "I started taking Phenergan to assist with ongoing bad allergies (to dust mites and pollen) and found it very effective for this, as well as guaranteeing me a good night's sleep. I only take a 10 mg dose about 1 hour before bed and no later than 8 pm if I want to wake early for exercise before work. I find if I take it any later, I am lethargic at 5:30 am and take a bit to get going. I have also used the syrup for my young boys as a rare sleep aid. Both my husband (who was prescribed it when he had an allergic reaction to penicillin) and eldest 5-year-old are affected by this antihistamine/sleep aid. It makes them groggy and crabby the next day. My youngest (3-year-old) and I have only positive effects from it."

• Doc...
• Taken for 5 to 10 years
• October 21, 2016

For Light Sedation "I have been taking Promethazine 25 mg tablets as needed for nausea for about 5 years. 1 pill would completely take away my nausea, even if I had the flu. However, the first time taking 1 pill knocked me out. You can build up a tolerance fairly quickly if you take them daily. I also have taken 1 to 2 pills to sleep through the night if I'm off work the next day because they make me groggy for a few hours the next morning. They don't make me feel 'out of it' like Xanax, and I have never developed any type of addiction to them either."

• Jan...
• Taken for less than 1 month
• October 10, 2020

For Sedation "Have taken promethazine for 3 nights, have been struggling to sleep for a couple of months now. Has done nothing but give me a slight headache around my temples. If anything, I feel like this has kept me awake."