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Protonix User Reviews & Ratings (Page 3)

Protonix has an average rating of 7.2 out of 10 from a total of 83 reviews on Drugs.com. 64% of reviewers reported a positive experience, while 22% reported a negative experience.

Reviews for Protonix

Commonly mentioned side effects
  • Mac...
  • March 7, 2009

For GERD "I love Protonix. Only wish it was more affordable. My insurance company will only cover the generic form-which is NOT the same. I found the name of the manufacturer, but again the insurance company won't cover it. The three months I was on the generic, all my symptoms returned. Back on the Protonix for two weeks and everything was gone!"

10 / 10
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61 Report
  • Anonymous
  • Taken for less than 1 month
  • March 28, 2018

For GERD "I took Protonix for about a week, and every time I took it, I got a severe headache every day. It did help to keep my heartburn at bay, but to me, it is not worth it for the side effects. My mood dropped because of this medicine, and I just did not feel like myself. I have stopped taking this medicine, and I am now taking Zantac 150 mg. Took effect, and it is working wonders for me."

1 / 10
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32 Report
  • Wag...
  • Taken for less than 1 month
  • October 6, 2016

For GERD "I have had severe GERD/acid reflux for nearly 6 years. It has put me in the hospital 7 times now and has totally destroyed my teeth, which I have always been meticulous about caring for. Presently, it's also causing me swallowing problems and voice troubles. The pain the GERD can generate is an actual true '10'-far, far worse than the pain I experienced from a quad cardiac bypass surgery. My doctor gave me Protonix for it, and it worked very well on reducing, perhaps, 80% of the pain. Unfortunately, the medication caused peripheral edema big time, and I had to go off of it again. The edema immediately went away, but the pain came back too. I have noticed this reaction from almost all proton pumps that I have tried to date."

5 / 10
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40 Report

Frequently asked questions

  • Tin...
  • December 16, 2017

For Barrett's Esophagus "I have been on this medicine for a while, and as long as I take it as I'm supposed to, I'm good. The only side effect is a headache for the first couple of days, but other than that, I really like this medicine. It's much better than being sick and in pain all the time."

9 / 10
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31 Report
  • Mar...
  • October 29, 2008

For GERD "I loved this drug-until my insurance company said it was the 'same' as another less expensive drug. I've been miserable ever since. The acid reflux is returning, I am bloated and bowels are always a surprise. My surgeon is thinking a second surgery might be needed - if only I could afford the Protonix, it could be avoided."

10 / 10
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57 Report

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  • Bad...
  • December 1, 2011

For GERD "I only discovered I had GERD from an endoscopy. I've always had a horrible stomach, but recently had a constant sore throat. The Protonix worked wonders! But then I noticed I was constipated and had a huge appetite. I briefly switched medicines but went back to Protonix. It was when I started taking it again and had two abdominal exams that I realized my liver was enlarged. The doctors immediately dismissed it since I've had my gallbladder removed. They said it was scar tissue. My daughter has eosinophilic colitis, so I'm really just focused on her gastrointestinal care, but at my next follow-up, I will address the issue. I did cut out milk/dairy from my diet, and that seemed to help as much as the medicine!"

7 / 10
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49 Report
  • Tes...
  • July 2, 2008

For GERD "I have a Lap Band. Before I had the band, I had no problem with heartburn. Then, after I got a couple of adjustments, I had acid reflux and heartburn so bad I was eating like 20 Tums a day. Zantac no longer works, or anything for that matter, so I went to my doctor, and he gave me samples of Protonix. Within minutes, my heartburn was gone. I have slept through the night without vomiting my own stomach acid. Highly recommend this drug. If you have a Lap Band, then you know how horrible it can be."

10 / 10
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51 Report

More FAQ

  • ric...
  • February 2, 2010

For GERD "My gallbladder was acting up, and the pain was terrible. I took a Protonix as soon as I got out of the doctor's office (with a sandwich and Dr. Pepper). About 15 seconds later, I was burping like crazy. Viola! The pain subsided considerably in less than 3 minutes. An hour later, it was like I never even had the pain! I felt much, much better."

9 / 10
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50 Report
  • tAn...
  • Taken for less than 1 month
  • December 11, 2017

For GERD "I have had acid reflux for 10 years. I've taken Nexium, it takes my reflux away. Now insurance will not pay, so now I have to take Protonix tabs 40 mg once per day. I get heartburn, heartburn so bad I have to take Tums 2 to 3 at a time. Just not happy. I must keep looking for better meds."

4 / 10
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22 Report
  • Ren...
  • Taken for less than 1 month
  • September 28, 2021

For GERD "Prescribed Protonix by my doctor, and after a week and a half, I had to stop. Almost immediately, anything I ate gave me heartburn (I didn't have frequent heartburn before), headaches every morning, extreme nausea, so much that I had no appetite, foggy brain, joint pain in my hands/wrists, abdominal pain, and depression/anxiety. I wish I would have done my research and asked more questions. I'm on day 2 after stopping, and I feel slightly better. I'm going to try a cleaned-up diet and not eating so late. Let us hope it works."

1 / 10
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11 Report
  • Anonymous
  • September 28, 2009

For GERD "I've had years of GERD without any food triggers and daily heartburn. Protonix was a dream! It is, however, very expensive. My insurance had it on its drug list and dropped it this year. A 30-day supply is $120! I've had to switch to Nexium."

10 / 10
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37 Report
  • Col...
  • Taken for 2 to 5 years
  • June 17, 2022

For Erosive Esophagitis "Protonix/pantoprazole worked great. However, I noticed I started gaining weight after several months. I made excuses for the weight gain but realized I wasn't eating much and was still gaining weight. When I gained 25 lbs after being on pantoprazole for a few years, I couldn't take it anymore. The weight gain was out of control and made me depressed. I decided recently to get off pantoprazole and go back to Pepcid AC. I have no idea how long it is going to take me to lose all this weight from taking this medication. I hope in the next 6 months I see some weight loss. Be careful taking this medication. Some doctors will swear it doesn't cause weight gain, while googling Protonix, you will find it actually does. Wish I had read on this site where someone else had weight gain from this medication and how long it took to lose it after getting off of it."

3 / 10
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10 Report
  • Anonymous
  • September 17, 2008

For GERD "Having suffered severe gastroesophageal reflux disease for many years, I have tried many remedies. Protonix gave me much-needed relief. Later, we also added 10 mg of Reglan at bedtime, followed by 1 oz of Gavison an hour later for extra protection. It's been 2 years since I had a severe attack and the overall reflux/acid has disappeared."

9 / 10
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32 Report
  • Aci...
  • Taken for 10 years or more
  • December 1, 2023

For Stomach Ulcer "Amazing life-saver when I wasn't able to eat anything without pain, which caused back pain. Was on Protonix, 2 tabs daily, for too long. The doctor prescribed this for over 20 years. Since Protonix removes 100% of stomach acid, it works like a charm to reduce pain from stomach ulcers, excessive acidic levels, and medications that cause excess stomach acid. However, it is recommended to take it for a shorter time as it removes too much stomach acid, which we need for bone density. I was recently switched to Pepcid, and I was scared the pain would resume - it did, but I'm getting through it. It's a must when medication can adversely affect important needs of your body. Protonix was a great management tool for me. Highly recommend for shorter-term needs."

10 / 10
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5 Report
  • Chr...
  • Taken for less than 1 month
  • June 27, 2022

For GERD "Awful! Ruined an entire ten-day vacation. Gas, stomach cramps, headache, alternating constipation and diarrhea. I had started taking a few days before the vacation and did not think much about it. I thought I had a stomach bug as it started just a few days into the vacation. On day ten, I realized it might be this med. I stopped, and within two days everything went back to normal."

2 / 10
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5 Report
  • Anonymous
  • March 22, 2009

"I rate it a 10. This is the only drug that helps my gastrointestinal problems. I have only been prescribed it twice in several years, but when it was prescribed, the drug took away the pain in the chest and it did not come back. It is great."

10 / 10
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13 Report
  • Kat...
  • Taken for 2 to 5 years
  • August 14, 2023

For GERD "In 2020, I went from 125 to 89 because everything I ate made me throw up. I was put on Protonix and immediately started feeling better. Later, I was diagnosed with GERD. No insurance until 3 years later, and now through all the testing, I discovered I have a large hiatal diaphragmatic hernia. It is the reason for my GERD, and the surgeon believes I won't have it after surgery. I realized how well it worked when they took me off for 7 days to do a manometry & pH probe. I started throwing up all my food again after 3 days. My hope is that after the surgery, I can get off the Protonix."

8 / 10
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  • Cze...
  • Taken for less than 1 month
  • June 22, 2014

For GERD "After two days on Protonix (for GERD associated with adult-onset asthma) I ended up in the emergency room with extremely high blood pressure, fast, pounding pulse, severe headache, and severe anxiety."

1 / 10
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179 Report
  • dal...
  • Taken for 2 to 5 years
  • May 25, 2013

For Stomach Ulcer "Works so well I forget I have a problem until I forget to take it, then I'm reminded the next day...ugh!"

10 / 10
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77 Report
  • SMS...
  • May 11, 2013

For Stomach Ulcer "I had 23 bleeding peptic, duodenal, and esophageal ulcers and GERD. This is helping."

9 / 10
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70 Report
  • lis...
  • October 27, 2008

For GERD "Tried everything, been on Protonix for 5 years. I can now eat anything as spicy and as hot as I like, and do not have acid reflux."

10 / 10
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71 Report
  • bam...
  • April 7, 2013

For Erosive Esophagitis "The only thing to work for me so far."

10 / 10
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60 Report
  • Cdi...
  • December 9, 2008

For Stomach Ulcer "Using this medication reduced the bloated feeling I had. It also reduced my appetite caused by the air pockets before I was using this drug. Great medicine with no side effects that I am aware of."

10 / 10
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70 Report
  • ly2...
  • Taken for 5 to 10 years
  • July 5, 2017

For GERD "I've had GERD and gastroparesis for over 10 years. Protonix is the only medicine I've found to help control the GERD. As long as I take it twice a day as instructed, I do not have acid reflux."

10 / 10
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36 Report
  • sie...
  • February 1, 2011

For GERD "This medication worked for me, reducing the stomach acid significantly. It is worth a try for anyone suffering from GERD."

10 / 10
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60 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.