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Xtampza ER for Chronic Pain User Reviews (Page 5)

Reviews for Xtampza ER

Commonly mentioned side effects
  • nan...
  • Taken for less than 1 month
  • March 26, 2021

"Have been taking this type of pain med for 1 week. Switched off Percocet. I have chronic neck, spine, and leg pain, in addition to a brain injury. This medication is not only expensive, I am back to pain that I had previously. Movement hurts: lifting, spine, right leg, and brain is like I felt after surgery. This is a shame and expensive."

1 / 10
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  • Bhu...
  • Taken for 1 to 6 months
  • November 18, 2020

"New pain doctor did not want to increase oxycodone to 4 times per day. Long story short, he prescribed Xtampza 13.5 @ 1 twice a day with 1 oxycodone 10 mg per day for breakthrough pain. I have to say it's not awful. It took a few days to kick in, but there have even been a few days that I didn't need the oxycodone! Chronic pain is awful!"

7 / 10
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  • Jim...
  • Taken for 6 months to 1 year
  • August 30, 2018

"I was taking 30 mg of OxyContin per day when Cigna suddenly stopped covering it. The doctor switched me to Xtampza ER 13.5 mg twice a day, and I was quite apprehensive after being on OxyContin for the past few years for an inoperable chronic back condition. I have been very happy with the new medication. It works as well as what I had been taking, and it seems to last longer. With OxyContin, I knew when the time was up, with this medication, I can go two to three hours over the time for the next dose and not have a problem. I also have the feeling that getting off this medication will be easier than getting off the OxyContin. I know it's basically the same medication, but it just seems to work differently."

8 / 10
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32 Report

Frequently asked questions

  • All...
  • Taken for less than 1 month
  • March 20, 2025

"A placebo could be more effective than this medication! Currently, there is a national shortage of MS-ER, causing my pain specialist to prescribe this useless medication. 5 years ago, the same doctor prescribed Xtampza ER, and I couldn’t function due to the excruciating pain 24/7! He actually admitted aloud that it was a huge mistake, so why I have been prescribed this yet again defies all logic and proper medical treatment. 18 mg, twice daily. An OTC Tylenol is more effective; in other words, it does not do anything to relieve ANY pain, but it certainly caused headaches, nausea, vivid nightmares, and extreme fatigue! Why is this medication still on the market? Very expensive, worthless for pain relief! I am currently unable to get out of bed, and my pain level is off the charts…"

1 / 10
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  • ano...
  • November 28, 2020

"I have been on OxyContin for many years for chronic pain. Insurance forced me off the brand name to a still decent oxycodone ER, which worked well. Now the distributor ran out, not sure if it will ever be restocked... (has been on back order forever now) my only option left was Xtampza ER, which, I agree with everybody else, does not work the same as OxyContin. I had to switch to Xtampza fairly quickly and now experiencing rapid heartbeat, sleeplessness, and it only seems to work from the neck up for pain effectiveness... awful stuff! I'm almost ready to pay out of pocket for the better medication."

3 / 10
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  • Kim...
  • July 1, 2022

"I was taking Percoset 10, 150 pills a month. Without consulting me, my doctor changed it to 120 pills and 30 Xtampza. He said to take 1 at bedtime and it should help me through the night. Maybe it did for the first couple of weeks, then nothing I could feel. I asked to be put back on the original prescription and was told they wouldn't do it. After 4 months of demanding not to take Xtampza, I am looking for a new pain management doctor."

2 / 10
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  • I...
  • Taken for less than 1 month
  • October 24, 2017

"I am at the end of my 1st week into my second week, day two. Like most of you, I cried in the doctor's office for fear of the level of pain I’d have to endure daily. My pain was as bad as all of yours. My first 4 days were awful, then each day a bit better. I finally began taking 1/39 mg capsule every 3/0.5 hours, through 6 capsules a day + 4/10 mg breakthrough pain tablets. As the days passed, I found I needed less breakthrough daily, and my daily pain was controlled like never before. Don’t get me wrong, I endure pain and not every day is perfect. But yes, I am very pleased and wish I tried them sooner when my OxyContin began to die down within 5/6 hours. The breakthrough was more of a joke. Xtampza gave me my life back."

9 / 10
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28 Report

More FAQ

  • Anonymous
  • Taken for 1 to 6 months
  • January 4, 2023

"I don’t like this drug. It provided no relief for me. I gave it an honest try but no benefit from it at all. My insurance doesn’t want me to get the OxyContin ER, and this was one of the suggestions. Miserable."

2 / 10
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  • Bir...
  • October 18, 2020

"I have been on oxycodone for years after a back injury that has resulted in multiple surgeries and two fusions. The pain relief didn't last long with the oxycodone, so we went to Xtampza for more continuous pain control. This has continued and has really improved my quality of life. I still have some pain, which I take IR oxycodone for, but I am actually on a lower total dose of opioids now than I was before Xtampza. I am back to living more, and my husband has commented so many times on how much happier I am. I have been able to walk my dogs again, work out, sleep all night, and do other things I missed so much. You need to take this with food. Your body won't absorb the med fully without a high-calorie meal. About four hours after taking Xtampza, I feel the effects pretty intensely. This lasts 1-2 hours, so I have to plan my day around that so I am not driving. I had stomach pain when I first started, but that subsided after a few days. These are really the only downsides I have had."

10 / 10
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  • ttl...
  • Taken for 1 to 6 months
  • August 23, 2017

"Works well for me now after a pretty painful period of switching/washing me out of the OxyContin regimen I was on prior. Give it time to get used to and should get similar results. After all, it's the same drug just packaged differently."

8 / 10
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29 Report
  • Nic...
  • October 12, 2017

"My advice would be to work with your doctor to find the appropriate dosage strength for your needs and also experiment with how often you take it (i.e., once in the morning for all-day relief, or one cap in the morning and then another at midday). I also recommend taking this with high-fat food. I've been told cottage cheese or yogurt helps. I think once you figured out the best way to take this drug, it works -- it certainly did for me. Be patient."

9 / 10
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27 Report
  • Gig...
  • Taken for 1 to 2 years
  • July 11, 2021

"You have to take Xtampza with about 12 to 14 grams of fat. I have experimented with higher and lower fat amounts, but 12-14 gm is my sweet spot. When I first tried it, I used butter, cheese, really HF foods. This made my cholesterol jump way up. Now I eat a palm full of walnuts when I take Xtampza. It works well for up to 8 hours for me."

8 / 10
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  • Rst...
  • Taken for less than 1 month
  • November 9, 2020

"Chronic pain from bone spurs in my neck and spinal degradation in my lower back. I have been on pain meds for ten years. I have tried everything except fentanyl. Hydrocodone worked best for me overall with no side effects like nausea or constipation. But my liver enzymes went above normal, and the doctor thinks it is caused by the Tylenol that is combined in the hydrocodone. I changed to morphine, which I had to stop because of the terrible nausea that got worse and worse after two weeks. She then put me on Xtampza. I do not like to wait over an hour for it to work. When it does kick in, it works okay, but it lasts only six hours most days...7 at the most. Pain relief is okay, but hydrocodone worked better for me even though Xtampza is supposed to be 1.5 times stronger. Xtampza does cause me slight nausea, but it also elevates my mood. I am going to try and talk to my pain doc to give me regular oxy. I don't know why she is reluctant to do so. Hydrocodone works better than Xtampza for pain in my case."

5 / 10
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  • mou...
  • October 7, 2017

"For me, it lasts about 5 to 7 hours depending on what I am doing. It does help, which is saying a lot for me, as not much seems to help anymore. I am glad that I got the opportunity to use this. Thank you!"

8 / 10
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21 Report
  • Nop...
  • November 17, 2017

"Actually, this is the most breakthrough med in this space that has been in a long time. There are a few posts on here stating that there is a “euphoric blocker,” when in fact that is completely false. It is the exact same molecule as Oxy, people...just it has the best abuse deterrent on the market. And for it or lasting for you 12 hours can be a variety of things. Your metabolism, body weight, etc. Every body processes meds differently. “No long-term effects” have not been studied because it’s only been on the market for less than 2 years...not a strong argument. Look at the long-term effects that on the oxy I’m assuming you want to be switched back to. Again, SAME MOLECULE!"

10 / 10
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  • Dis...
  • Taken for 6 months to 1 year
  • October 15, 2021

"Well, I've been on this about a year now after being on 15 mg OxyContin for 2 years. I finally felt like my pain was being controlled and was able to do more for myself. When my Medicare stopped covering it, I was put on 13.5 mg Xtampza. Since then, my pain is not controlled, and now I have unexplained stomach attacks that have been getting worse and more often. Last week, they cut me back half on my 5 mg breakthrough pills from 2 a day to 1 a day. I feel trapped in a broken, painful body that will never go away. I am now struggling to even cook dinners for my kids. No one is protecting chronic pain sufferers from opioid abusers."

3 / 10
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  • Din...
  • Taken for 10 years or more
  • March 20, 2021

"I have been taking pain meds for years due to injury to my spinal column. I see a lot of complaints about Xtampza ER here, and this concerns me. I have taken it for over a year (insurance company issues, like all!) and have had no issues with the difference. I have taken several types of ER through the years without issue. I was just switched to Rhodes on 15 mg breakthrough and am concerned with all the feedback. However, confused, given that the company is owned by the name brand Purdue. Will update in a few weeks with my experience, but please don't avoid Xtampza JUST from these remarks below."

9 / 10
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  • Kin...
  • Taken for 1 to 6 months
  • August 12, 2021

"Unless you can wake up and eat a high-fat/high-calorie meal, this drug sucks. You cannot get it to release all of the drug without it. Read ALL of the documentation. Otherwise, you only get about 40% of the meds. I would tell anyone who has been prescribed this to go back and ask for morphine sulfate (generic OxyContin). It is a LOT cheaper and much more effective."

1 / 10
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  • lit...
  • Taken for 5 to 10 years
  • November 23, 2022

"I began using Xtampza 13.5 ER and supplemented with Percocet 5/325 four times as needed. I am now using Xtampza 27 ER and supplement with Percocet 10/325 four to five times a day (mostly take four) as needed, which has greatly reduced my chronic pain. I eat anything I want with no weight gain. It has taken over five years of using Xtampza and Percocet to be very effective in reducing my chronic arthritis pain. I use MiraLAX to control constipation."

9 / 10
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  • Yel...
  • Taken for 1 to 6 months
  • January 2, 2022

"Does not work for my pain. I need something that works right away when feeling pain that gets worse as the day goes on. I have knee, lower back, top of feet, hands, and shoulder pain. I work, so as the day progresses and I am on my feet all day, the pain can become unbearable. I want something that works right after I take it. This medication hasn’t helped any."

2 / 10
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  • Pam...
  • Taken for 6 months to 1 year
  • April 11, 2021

"Due to a job injury, I've been disabled for 9-10 years. I've taken all kinds of meds. Then, finally found Xtampza 18mg my pain dr put me on it. I'm happy to say that they WORKED for me until the so-called I fell into the so-called 'donut hole' in my insurance. Price went from $25.00 to $165.85, so I say to you, raise your hand if you would be able to afford to pay for that every month with disabled income. I NEED HELP TO PAY OR LOWER THE PRICE. PLEASE, PLEASE, I'm hurting so bad every day, each step I make hurts."

10 / 10
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  • MS ...
  • October 17, 2022

"I have found that it works very well in combination with immediate release. I have tried several different medications for years, and this is certainly noticeably much more helpful in managing severe pain. I would recommend use in combination with immediate release. I suffer from multiple pain management complications from spinal fusions to remitting progressive MS. This combination has helped me get through many days of very difficult, painful flare-ups, from bilateral sciatica to a crushing sensation in my left arm, which is constant."

10 / 10
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  • TJo...
  • Taken for less than 1 month
  • December 7, 2021

"I was on Oxaydo 5 mg 4 x day. I was undertreated but was afraid to complain. It barely touched my pain. I was put on Xtampza ER 9 mg every 12 hrs. What a joke! It's worse than Oxaydo! They told me that Oxaydo was no longer available. Now I suffer waiting for my next appointment. Will the doctor switch me to something that will work? Xtampza needs great improvement."

1 / 10
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  • Goo...
  • Taken for less than 1 month
  • March 22, 2018

"Today went off the Fent for good. Doc prescribes Xtampza. I told Doc I will try it, but no more patches. If the product does not control my pain, it too will be gone. I refuse to pay what I pay for insurance, be in pain 24/7 and not be able to find something to control it. The pharma game of money roulette is over. The 2 major surgeries with hardware, new L5 disk several thousand over 8 years. Nope."

5 / 10
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  • Luc...
  • Taken for 2 to 5 years
  • December 11, 2020

"I have been on opiates for over 30 years. Eventually, I was put on Suboxone to manage addiction with Xtampza for chronic pain. Because of the Suboxone, I have to take at least 72 mgs of Xtampza to get any relief. It takes about 4 hours to kick in and then lasts for about 4 hours. I only get about 8 hours of coverage (not 12), but I imagine that is due to the Suboxone taking up so many of the receptor sites."

5 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.