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Xtampza ER for Chronic Pain User Reviews (Page 3)

Reviews for Xtampza ER

Commonly mentioned side effects
  • Pai...
  • Taken for less than 1 month
  • March 14, 2019

"I have 4 herniated discs in my neck, two failed right shoulder rotator cuff surgeries, back surgery on L5, and esophageal cancer that has not spread (thank God). I'm starting on Xtampza ER in a few days for this chronic pain and was very nervous, however, it's time. I was taking four 15 mg oxy IR. Down to four 10/325 Percocet and will now be trying two x 18 Xtampza plus one breakthrough. After reading some of the real comments from people switching to Xtampza, that the drug actually works, I feel more confident. I will report back once I'm taking to give a full and honest report. I will give an honest report back as I'm not looking to get high - I just want to manage the pain so I can live a subpar but somewhat normal life, what I have left. Good luck to all of you with your pain management issues."

8 / 10
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58 Report
  • Fee...
  • April 25, 2019

"Since I was just switched to Xtampza ER on 4-19-19 and have been taking 9 mg twice daily for a week. So I really can't say too much other than I have had headaches daily starting one day after starting the medication and has not let up yet. I was told that this drug would last longer than my current medication, which was OxyContin 10 mg twice daily. So far, neither has lasted the 12 hours as it claims. I am lucky to get 5 to 6 hours of relief per dose. Neither gave me complete pain relief, but some was better than none. My pharmacy said they have never had anyone prescribed this medication before me. I was lucky enough to get my script at my monthly doctor visit. The pharmacy had to special order the medication but could not order it until they got a prior authorization from the doctor or my insurance would not process. At this point, I do not feel that I am getting the relief I was getting previously as far as the length of time. I was down for 2 days with a bad headache out of the 7 days on this medication."

2 / 10
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49 Report
  • All...
  • Taken for less than 1 month
  • March 20, 2025

"A placebo could be more effective than this medication! Currently, there is a national shortage of MS-ER, causing my pain specialist to prescribe this useless medication. 5 years ago, the same doctor prescribed Xtampza ER, and I couldn’t function due to the excruciating pain 24/7! He actually admitted aloud that it was a huge mistake, so why I have been prescribed this yet again defies all logic and proper medical treatment. 18 mg, twice daily. An OTC Tylenol is more effective; in other words, it does not do anything to relieve ANY pain, but it certainly caused headaches, nausea, vivid nightmares, and extreme fatigue! Why is this medication still on the market? Very expensive, worthless for pain relief! I am currently unable to get out of bed, and my pain level is off the charts…"

1 / 10
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Frequently asked questions

  • Gem...
  • Taken for less than 1 month
  • April 19, 2020

"Had spinal fusion surgery that left me with more pain than I had pre-surgery. I was burning through 10/325 Percocet, so my pain management switched me to Xtampza 18 mg. 1st night had such a bad nightmare I refused to go back to sleep. This med caused insomnia on some days or sleep with horrific dreams. As for pain, it did manage my pain, but I hope I am not required to be on it for a long amount of time. I mixed it with 1 tablespoon of peanut butter and it seems to work well that way. It is also on the pricey side, even with insurance."

8 / 10
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  • Cat...
  • Taken for 1 to 6 months
  • April 20, 2023

"This medicine is worthless. I have scoliosis, spine arthritis, shoulder pain, and bone-on-bone hips, have had 4 back surgeries, and neck surgery. I was forced to stop taking hydrocodone four times a day as it's a chasing pain medication. So they say. I know my body and what works for me. This medicine does not work! I honestly feel it's just an overpriced placebo."

1 / 10
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  • Anonymous
  • January 10, 2019

"Very disappointed. Was on morphine sulfate 100 mg. My doctor wanted me to try Xtampza. Not impressed. They just gave me headaches and stomach pain with no relief from my chronic pain, plus with insurance, it cost me $273.00. Will not use this again."

2 / 10
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  • Inj...
  • Taken for less than 1 month
  • April 11, 2023

"This product should not even be on the pain medication list for doctors. Nothing but nausea, headache, anxiety, and added pain!!! Don’t waste your money because most insurance doesn’t cover it!!! GARBAGE!!!"

1 / 10
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More FAQ

  • Tnt...
  • Taken for 1 to 6 months
  • February 19, 2019

"After years of trial and failure to control the chronic pain, this med has done what none other has. I have been on 150 mg Lyrica 3/day, Morphine ER, fentanyl patch, and many other meds for over 15 years. All those other meds became ineffective and offered little relief. Now, 2 months into twice daily use of Xtampza, I finally have a new baseline. Though I still take other meds and a breakthrough painkiller occasionally, I don’t feel as though there’s no help. It’s not cheap, and my various prescription coverages still didn’t cover all the costs. I still firmly believe I’m better off with this medication, and if offered to others, it may be what you’ve needed for a long time."

9 / 10
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  • Tri...
  • Taken for 6 months to 1 year
  • August 5, 2018

"I'm not getting any relief from this medication. My doctor prescribed the 9 to be taken twice a day. Since I also take oxycodone 10, three times a day, the doctor said it would be the equivalent to the oxy 10 but last around the clock. Also, I was wondering if anyone has noticed weight gain. I have put on 30 pounds in a matter of months, which I have never done before. Maybe it's my system or too low of a dose, but my doctor will not up it for anyone. I have also had a lot of crazy dreams, and my blood pressure has gone up quite high, causing me to be put on medication for it."

1 / 10
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  • Bat...
  • Taken for 1 to 2 years
  • September 27, 2020

"I was forced to switch to Xtampza. I've been taking it for about a year now. I want my OxyContin back! The Xtampza simply does not work as well. I've also noted more breathing problems on Xtampza. I get dizzy and have more stability problems on Xtampza. In my book, OxyContin is still a better choice for chronic pain."

3 / 10
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35 Report
  • Dal...
  • November 9, 2017

"My last post was taken down. Been on this for a few months. Honestly, we have to stop changing medicine that works, just because of the small percentage that abuse these drugs. Side effects: dizzy, nausea, severe headaches, which I never had before. I feel numb to the world, tired, and still in pain. Also found out that long-term effects of this drug have still not been studied, and there is a euphoric blocker in these that stops you from experiencing well-being. I get it, the well-being is what addicts crave, but for people in chronic pain, well-being is a good pain reliever, as moods affect our pain. The medication is supposed to last 12 hours, they don't, they last about 5-6 hours. It also only takes the edge off the pain."

2 / 10
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  • Fre...
  • Taken for less than 1 month
  • October 27, 2022

"A big caution - this drug requires you to have a gallbladder and a fully functioning bile system or your body will not absorb it. If you are being taken off another opiate, you will suffer major withdrawal symptoms as the Xtampza won't be absorbed and you will have stopped your original opiate. Can you spell cold turkey? It happened to me and it sucked!"

1 / 10
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  • Bir...
  • Taken for 1 to 6 months
  • October 2, 2018

"I was diagnosed with stage 4 breast cancer. It spread to my bones and lungs. I started with morphine, and it just didn't hold the pain. My doctor then changed my prescription to Xtampza ER 13.5. That didn't hold for 12 hours. Went to 27 ER. It held for about 6-7 hours. If anyone has stage 4 breast cancer and is comfortable, please let me know."

3 / 10
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  • Dou...
  • Taken for less than 1 month
  • July 18, 2020

"Dr. changed my Percocet to Xtampza ER after I refused non-effective injections. My dose I'm taking is 18 mg times a day. I have had severe migraines, dizziness, nausea, sharp pains in my side, itching real bad. Worst medication ever. Even took Benadryl and Allegra, doesn't help. Changed to 1 time a day, still the same. Dr. called in lower dosage but ignores the side effects."

2 / 10
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36 Report
  • Eri...
  • Taken for less than 1 month
  • April 5, 2018

"I was trying this medication after being on OxyContin for the last 2 years and after getting on a Medicare Advantage plan that didn’t cover the OxyContin. It takes 1-2 hours for the onset of Xtampza, and it only lasts 8 hours at best, usually 6-7. Nowhere near as effective as OxyContin for relief of chronic pain for me."

2 / 10
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42 Report
  • Pow...
  • Taken for less than 1 month
  • January 23, 2018

"I have been on pain meds since Oct 2007. Just started Xtampza ER, and it takes 4 hours to work. Then it hits hard, breaks into a bad sweat, and in 3.5 to 4 hours, it stops working. This should be taken off the market."

1 / 10
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  • Sad...
  • Taken for 1 to 6 months
  • July 17, 2018

"I have been on this med because of insurance changes as well. Was on OxyContin 20 mg 2x day plus three 10 mg a day. Still having a lot of pain but somewhat of an existence and able to work some. Been on Xtampza 18 2x day, have had to go up on breakthrough, and the doc's not happy. Keeps telling me to give it time. It's been 3 months. My biggest complaint is its inconsistency. Some days it works okay, and the next I find myself waking up sneezing. It's a shame how bad of a four-letter word pain is anymore, and if you speak up or complain, you worry your doctor will send you packing. And this month my copay for this changed, same rules and cost as OxyContin, but can't have that back according to doc."

3 / 10
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40 Report
  • cam...
  • Taken for 1 to 6 months
  • September 1, 2018

"I have been in chronic pain for 22 years. I was forced to switch to this med two months ago. It does not relieve my pain, and I gained 20 lbs. in one month. It also gave me migraines. Will not take it again."

2 / 10
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39 Report
  • Pol...
  • Taken for 1 to 6 months
  • February 20, 2020

"I was started on this because my insurance wouldn't cover my previous long-acting med. I was very leery, as the others don't really last 12 hours, and breakthrough meds are a thing of the past. But I'm pleasantly surprised. It does have a longer duration, and it seems to work more like the other ER was supposed to."

9 / 10
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35 Report
  • Kri...
  • Taken for less than 1 month
  • January 14, 2018

"I suffer from severe, chronic back, neck, and shoulder pain. This is one of the worst medications I've ever taken. The nausea and dizziness are awful. If that were the only negative side effect, I think I could live with it, though. What I found extremely disturbing was the psychological effects. After only two doses, I had terrifying nightmares that were difficult to awaken from. I, uncharacteristically, felt like Alice in Wonderland in an extremely unpleasant manner while I was awake. I can't believe this medication is on the market. Not to mention, it did absolutely nothing to help with pain."

1 / 10
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  • Mom...
  • Taken for 1 to 6 months
  • December 5, 2020

"Xtampza does not work. It says take 1 every 12 hours. For me, it lasts around 3-4 hours max. I also take 800 mg ibuprofen. Oxycodone 10/325 worked well. It would give me 4 hours during the day, where I was pain-free. I felt like I had a little bit of a life. Anyway, I fell, which caused a compression fracture in L1 on my spine. My doctor knows how much pain I'm in and prescribed me oxycodone 20 mg. My insurance made me get the 'generic' one. So now I have to go to a pain clinic. My appointment is on the 10th. So, that's my story. It does not work."

4 / 10
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30 Report
  • chr...
  • Taken for less than 1 month
  • February 4, 2017

"Did not notice any relief in pain. I did develop welts on my face, hot eyeballs, itching like crazy, nauseated most of the time. I also felt as though I constantly had the flu. I would like to go back on Norco 10/325 x 6/day or oxycodone 15 mg / 6 day. Oh - severe constipation. Really disappointed!!"

1 / 10
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47 Report
  • Sbc...
  • April 18, 2017

"Horrifying. The onset for relief is 2 to 3 hours. Then it runs out of pain relief within 5 to 6 hours! If they are trying to hit the abusers, make drug and alcohol treatment accessible! And the cost is 3 times more than OxyContin...?!?!? Go figure..."

4 / 10
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52 Report
  • Ter...
  • Taken for 6 months to 1 year
  • March 7, 2023

"Xtampza does not work for me, in fact, I believe it gives me more pain. As I get hot flashes and neuropathy now on top of my other problems. This medicine absolutely does not help me, yet I’m forced to take this garbage. My insurance company pays over a thousand dollars for what is essentially garbage. My former medication worked well, but they don’t want to prescribe it anymore. All this medication does is torture me. I can’t stand this. We need medication that works!"

1 / 10
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  • Kat...
  • Taken for less than 1 month
  • January 20, 2022

"I've been a pain patient for nearly 20 years due to Ehlers-Danlos syndrome. Switched from generic MS Contin 15 mg twice a day to Xtampza 13.5 mg twice a day. One word: torture. Constant GI upset with diarrhea and feeling like my insides are writhing with worms. A complete lack of dreaming (no darkness, just like being turned off and on again) with horrifying intrusive thoughts and mood swings. Pain in parts of my body where I didn't have pain before, or where pain was previously well-controlled. Feeling dangerously high and then going into total withdrawal (I kept the Narcan on my bedside table and told my family to check on me). I took it with a fatty meal, the same meal every time, and had a different experience every 12 hours. At no time did I feel safe taking this medication. This has left me feeling terrified to try anything else and suspicious of my doctor's reasons for switching me. I firmly believe this medication was manufactured to scare people away from opioids."

1 / 10
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20 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.