Skip to main content

Ondansetron and Nausea: What Users Say (Page 5)

Reviews for Ondansetron

Commonly mentioned side effects
  • Gma...
  • Taken for less than 1 month
  • May 18, 2018

For Nausea/Vomiting, Postoperative "I had dental surgery, was given one dose of ondansetron. Had an extremely bad reaction. Experienced nausea, vomiting, dry heaving, muscle twitches, seizures, couldn't open my eyes but could still hear. Three days could not eat and took sips of cola as advised by my local EMT (yes, they called 911 on me as I did feel like I was dying). Had trouble with my eyes adjusting while trying to focus, my vision would snap in and out. Now, with all that said, I have taken ondansetron several times before with no problem. You just never know."

1 / 10
Was this helpful?YesNo
2 Report
  • Anonymous
  • Taken for 1 to 2 years
  • September 14, 2012

For Nausea/Vomiting "It helps. I get a really distinct nausea in the night, maybe once a month. I know it when I wake up feeling sick, and then my whole body starts to heat up. I take Zofran right away. I still have episodes of almost vomiting, dry heaves, I guess, but it keeps it down. Takes a few hours for the symptoms to subside-usually means I'm up half the night, but I'm terrified of throwing up, so this is one of the best prevention medicines. This and ginger tea are my go-to remedies. That said, if I don't fully sleep it off, I end up with a hangover in the morning."

9 / 10
Was this helpful?YesNo
3 Report
  • Leg...
  • Taken for less than 1 month
  • June 8, 2018

For Nausea/Vomiting "I was nauseous and throwing up for a couple of days with no appetite. Because I didn’t eat enough, which made me nauseous, then the throwing up made it impossible to keep any food down. I was prescribed ondansetron (he said to let it dissolve under my tongue, so even if you throw up, you’re good). I threw up again almost immediately after, but two minutes later, I had no nausea whatsoever. I also was able to drive 4 hours afterward too, so it didn’t make me drowsy at all either."

9 / 10
Was this helpful?YesNo
2 Report

Frequently asked questions

  • Col...
  • Taken for less than 1 month
  • June 20, 2012

For Nausea/Vomiting, Postoperative "Was taking the pain medicine Tylox after ACL repair and broken femur. Although the Tylox helped tremendously with the pain, I would get a nauseous feeling and vomit even when I ate before taking Tylox. The doctor gave me a prescription for ondansetron, and it worked beautifully. I take it 10-15 minutes before I eat and take the Tylox 10-15 minutes after I eat... no more nausea! Yay."

9 / 10
Was this helpful?YesNo
2 Report
  • Han...
  • February 25, 2016

For Nausea/Vomiting "I suffer from Crohn's colitis, and I also have severe PTSD anxiety. I was constantly nauseous and puking off and on for a week straight. I went to the ER, and they prescribed me this medication. I took the medication, it took away symptoms for just a few minutes, and I was back to puking 45 minutes later. I hate these pills!"

4 / 10
Was this helpful?YesNo
6 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
  • Myh...
  • May 6, 2016

For Nausea/Vomiting "Took this for nausea due to flu. It might have helped, I'm not sure, but I took it twelve hours ago, and now I have the worst headache of my life, and nothing gets rid of it. I can't move, and I'm very dizzy. Also slightly nauseous. Phenergan would have been better. Also, this stuff tastes gross, and I almost puked trying to swallow it. Would not take this again."

2 / 10
Was this helpful?YesNo
6 Report
  • Anonymous
  • January 13, 2010

Ondansetron for Nausea/Vomiting "I received this medicine with Stadol for a migraine. Within 20 min, I vomited. I hadn't vomited with the migraine, just had nausea. I got out of bed once after a few hours and threw up again, then again after trying only water. So... this didn't work at all for me, but I'd never had either of the two drugs before."

3 / 10
Was this helpful?YesNo
7 Report
  • Anonymous
  • September 9, 2010

For Nausea/Vomiting "Significantly helped reduce my nausea and vomiting due to hyperemesis during pregnancy. Prior to taking this medication, I had nausea 24/7 and was vomiting excessively for weeks. I lost 15 pounds and had to be given IV fluids and nutrients. Once prescribed this medication, I was able to eat and drink again and had much less nausea and no vomiting for about a week. However, I did notice a reduced effectiveness over time. The nausea increased and I began vomiting daily again (although with less vigor and less frequency than before). I'm not sure why it is less effective now than it was at the initial use, but I still am satisfied with the improvement of my condition."

8 / 10
Was this helpful?YesNo
2 Report
  • HTL...
  • Taken for 1 to 6 months
  • September 27, 2021

For Nausea/Vomiting "I have chronic nausea due to my chronic migraines, plus the meds I take for my migraines make me nauseous. My doctor prescribed this, and it does help me. I don't feel like throwing up anymore, and I wish I had it sooner instead of suffering. With the nausea better under control, I feel better to eat now. Has been great for me."

10 / 10
Was this helpful?YesNo
0 Report
  • anc...
  • Taken for 1 to 2 years
  • February 24, 2023

"I’m a 23-year-old female with ulcerative colitis, and I go through severe flare-ups, and one symptom of those is horrible nausea. I take the ondansetron dissolvable tablets, prescribed one every 8 hours, and I truly get some relief from the pain. It starts working within the hour for me and lasts me at least 4-5 hours. It’s not a cure for the nausea, but the relief it gives me makes taking this medication very worth it. (Also, chamomile tea helps with my stomach pain and nausea.)"

9 / 10
Was this helpful?YesNo
0 Report
  • Med...
  • Taken for 1 to 6 months
  • August 4, 2021

For Nausea/Vomiting, Postoperative "Think some reviews are suspicious since the CDC wanted Phenergan, which was 10 times the medication Zofran is. The headaches are severe, and nausea/vomiting hits without warning. I tried but could not tolerate the pain and misery. Phenergan was by far superior and boosted mood because it was such a good medication and better than Zofran or any so-called antidepressant. I can't believe Zofran has replaced other medications in hospice comfort packs."

1 / 10
Was this helpful?YesNo
1 Report
  • Jua...
  • September 23, 2015

For Nausea/Vomiting "Nausea/vomiting. Took tablet 45 minutes before lunchtime, and I still needed to slow down to avoid building nausea toward Cheerios and a banana. Lunch is 50 minutes long, and it still did not curb nausea with food I considered safe. Thinking there might still be some coverage 6 hours later, I tried eating a carrot, but my body quickly rejected it."

3 / 10
Was this helpful?YesNo
3 Report
  • JUS...
  • Taken for less than 1 month
  • September 11, 2022

Ondansetron for Nausea/Vomiting "I've been traveling and taking Zofran. In the past, if I took Zofran once, it seemed to be okay. But after taking multiple doses these last few days of travel, I've been having nausea, vomiting, diarrhea, muscle spasms, and numbness/tingling in my limbs. When I would feel a little off, I would take Zofran, not realizing that it was making things worse for me! I also looked up any possible drug interactions, and it appears that it has a major negative interaction with Zoloft (which I take!). It's ruined the first part of my trip, and I'm praying that I can start feeling better so I can enjoy the trip that I have dreamed about for decades now!"

1 / 10
Was this helpful?YesNo
2 Report
  • Chy...
  • July 22, 2019

For Nausea/Vomiting "I have a really bad stomach bug, been puking for 2 days, and I'm so very nauseous when I'm not puking. The doctor prescribed this to me today to help. I've only been able to drink water and keep it down today. Food makes me want to vomit, even smelling it. I took one of these around 4, and it hasn't helped in the slightest. I'm also breastfeeding a 10-month-old, and my boobs are really small now. I'm so very worried. I hope this goes away soon :( sad it hasn't helped yet."

3 / 10
Was this helpful?YesNo
1 Report
  • Rip...
  • Taken for 2 to 5 years
  • March 30, 2025

Ondansetron for Nausea/Vomiting "Pleasant taste, disintegrates quickly, and feels a little like Pepto-Bismol how it 'coats' your gut. To be honest, it's only slightly better working than Pepto, but certainly more convenient and better tasting. I'm a little shocked at the listed side effects... it's very tame to me, never anything negative on the 8 mg pill. If anything, it just doesn't do the trick... (nausea from recurring diverticulitis)."

7 / 10
Was this helpful?YesNo
0 Report
  • Kel...
  • Taken for less than 1 month
  • July 19, 2019

Ondansetron for Nausea/Vomiting "Using Zofran for my 14-year-old daughter. It has not helped her nausea. It seems to make it worse, but she can’t vomit to release the pain. At least when the Zofran wears off, she can vomit and get some relief. We’ve tried it three times and will never use it again for her. (She just had her tonsils out.)"

1 / 10
Was this helpful?YesNo
6 Report
  • Sto...
  • Taken for less than 1 month
  • January 8, 2022

Ondansetron for Nausea/Vomiting "Took for a few days after getting food poisoning, which turned into a stomach virus. It worked for an hour or two, but the nausea came back worse. No vomiting, surprisingly, but didn’t really help my nausea."

2 / 10
Was this helpful?YesNo
0 Report
  • Dis...
  • Taken for less than 1 month
  • November 22, 2021

Ondansetron for Nausea/Vomiting "I took ondansetron swallow pill at 4 mg, and it was starting to help. My physician increased the dose to 8 mg, but it was now a mouth-dissolving format and made my nausea far worse. Pharmacy says they can distribute 8 mg in the swallow pill form, but the doctor has to prescribe it in that format."

1 / 10
Was this helpful?YesNo
0 Report
  • Kay...
  • Taken for 6 months to 1 year
  • September 1, 2019

Ondansetron for Nausea/Vomiting "Seriously, this is a magic pill. I get nausea as a symptom from my anxiety, and after taking one Zofran, my nausea is completely gone within 20 minutes (sometimes less)."

10 / 10
Was this helpful?YesNo
32 Report
  • Amy...
  • February 10, 2016

Ondansetron for Nausea/Vomiting "I was prescribed Zofran because I was constantly nauseous and depressed because of a personal matter. Yes, they taste awful, but they work 100% of the time! And they work quickly!"

10 / 10
Was this helpful?YesNo
34 Report
  • Ery...
  • August 19, 2014

Ondansetron for Nausea/Vomiting "Only thing that works! I have MSK and vertigo, and BOTH cause nausea with flare-ups, and this is my lifesaver!"

10 / 10
Was this helpful?YesNo
27 Report
  • Ms ...
  • January 9, 2015

For Nausea/Vomiting "Was prescribed this medicine due to problems associated with GERD that had me very nauseated. This medicine works great-immediately."

10 / 10
Was this helpful?YesNo
16 Report
  • Goo...
  • July 10, 2016

Ondansetron for Nausea/Vomiting "Had kidney stones. Took pain meds for it. Got super nauseous at night. Took Zofran, and within 10 minutes I was not nauseated at all. Amazing medicine."

10 / 10
Was this helpful?YesNo
17 Report
  • AMY...
  • August 15, 2008

Ondansetron for Nausea/Vomiting "I have suffered with migraines for years; with them comes nausea and vomiting. I have just started taking Zofran twice. Thank goodness it has helped. I was tired of suppositories."

8 / 10
Was this helpful?YesNo
18 Report
  • Tri...
  • December 7, 2015

Ondansetron for Nausea/Vomiting, Chemotherapy Induced "Sadly, oral Zofran (or at least the generic of it) was not enough to combat my nausea while on GDP. However, intravenous Zofran along with hydration did help."

5 / 10
Was this helpful?YesNo
8 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.