Ondansetron and Diarrhea: What Users Say

• Sug...
• Taken for 6 months to 1 year
• October 6, 2019

Ondansetron for Nausea/Vomiting "I have several chronic conditions, and one is called Cyclic Vomiting Syndrome. It's even worse than it sounds. I'm over 40 and have suffered since childhood. Gravol stopped working over a decade ago. Last December was particularly bad with many trips to the ER, and I finally got lucky and was given this. It's a miracle drug for me about 95% of the time. I do get some side effects like diarrhea and sweating, but they're very bearable. I don't go anywhere without a bottle of these."

• Anonymous
• April 10, 2009

Ondansetron for Nausea/Vomiting "I was given Zofran for all-day morning sickness during pregnancy. It works very well, but causes constipation, stomach cramps, and diarrhea. If I wait at least 12 or more hours between doses, the side effects are milder and the nausea is almost completely gone. Before I had this drug, I was miserable and missing work."

• mar...
• Taken for less than 1 month
• January 12, 2019

Ondansetron for Nausea/Vomiting "I have had severe nausea and vomiting 2 times in 2 weeks from eating seafood, so I'm guessing no more seafood. The nausea stopped after taking 2 pills. Threw up the first time, then the second one stopped it within 20 min. I'm so happy. The first time I had nausea, vomiting, and diarrhea for 5 hours, had to go to the emergency room. Once diarrhea stopped, they gave me this medication, and all stopped."

• Vin...
• Taken for 1 to 6 months
• September 7, 2018

Ondansetron for Nausea/Vomiting "I take another drug that causes severe nausea. Zofran was prescribed; the nausea stopped, but the other side effects from Zofran were so overwhelming that I had to stop taking it. The side effects were diarrhea, headaches, blood in stool, dizziness, and yes, nausea. I couldn't drive, so I'll live with the nausea until I see my endocrinologist again and (maybe) he suggests something else. Bottom line: the side effects of Zofran outweigh the benefits."

• Mic...
• Taken for less than 1 month
• December 3, 2014

For Nausea/Vomiting "I was in the hospital for 11 days, diagnosed with failing kidneys, which made me highly nauseated. I've lost 20 lbs. in 2 months. The shots worked quicker for me than the 4 mg pills I'm taking at home. But reading through the posts, I now know why I was severely constipated, and I normally suffer from irritable bowel syndrome...constant diarrhea. My kidneys continue to deteriorate, which causes the nausea. As far as the person who mentioned they stopped taking it because of a headache...the headache probably came from extreme vomiting or the blood pressure going up from the stress of vomiting. That's what happened to me. I would give it another try."

• JUS...
• Taken for less than 1 month
• September 11, 2022

Ondansetron for Nausea/Vomiting "I've been traveling and taking Zofran. In the past, if I took Zofran once, it seemed to be okay. But after taking multiple doses these last few days of travel, I've been having nausea, vomiting, diarrhea, muscle spasms, and numbness/tingling in my limbs. When I would feel a little off, I would take Zofran, not realizing that it was making things worse for me! I also looked up any possible drug interactions, and it appears that it has a major negative interaction with Zoloft (which I take!). It's ruined the first part of my trip, and I'm praying that I can start feeling better so I can enjoy the trip that I have dreamed about for decades now!"

• Gee...
• Taken for 1 to 6 months
• December 13, 2020

Ondansetron for Nausea/Vomiting "I was warned of the possibility of severe vomiting/diarrhea due to chemotherapy for treatment of Glioblastoma. I have 10 days left on treatment, and so far, no side effects at all!"