Ondansetron and Tiredness: What Users Say

• Hgg...
• April 22, 2021

Ondansetron for Nausea/Vomiting "I have hyperemesis gravidarum (HG) and have been miserable. Zofran is keeping me out of the ER right now. At first, I noticed it made me a little dizzy, and it still makes me feel just a little weird within the first hour, but it’s extremely tolerable. The constipation is super annoying, but talk to your doctor about it if that’s an issue, and you can probably take something to help that. It stops me from throwing up, but I am still definitely nauseous. Brings it from like a 10 to a 5 or 6 maybe, but I can EAT now. That is huge. I am eating small meals when I haven’t had a meal in weeks. I’ve been barely eating and drinking. I am completely dependent on Zofran to be any type of functional right now. It makes me a little tired but also gives me more energy to not just stay in bed all day because it makes me feel better. Highly recommend, just watch out for the side effects I mentioned. Nothing to be scared of, extremely tolerable for me :)"

• OLo...
• Taken for 1 to 2 years
• May 3, 2014

Ondansetron for Nausea/Vomiting "This medication works wonders for me whenever I feel sick or nauseous. The flavored tablets that disintegrate under the tongue or in the mouth are very convenient and work really quickly to relieve nausea/vomiting. The only real side effect from it that I have noticed is a slight tired feeling. I'd much rather feel a little sleepy than sick to my stomach. I really recommend this medicine if your doctor also feels that it is right for you."

• car...
• February 2, 2008

Ondansetron for Nausea/Vomiting "My doctor prescribed this to me for pregnancy-induced nausea and vomiting. All of my pregnancies were horrible with nausea and vomiting. Well, this time I'm about seven weeks pregnant, and I have been taking the generic brand ondansetron orally dissolving tablets, they are small with a minty flavor. It melts quickly, and I must say I have not vomited one time this pregnancy. I have had mild tiredness, headache, dizziness, and much better than nausea and vomiting and being unable to eat."

• Smi...
• Taken for 2 to 5 years
• March 14, 2022

Ondansetron for Nausea/Vomiting "Zofran is the best drug for nausea! I suffer from Cyclic Vomiting Syndrome, which doctors say is the worst form of nausea. I get extreme nausea that doesn’t get better after vomiting, and each time I have a flare-up, it lasts 12 hours. Zofran is the only thing that will stop it. It makes me a little tired, but I’ll take that any day over the nausea. I use the disintegrating tablets, which are great for when you feel like you can’t swallow a pill from the nausea."

• Aly...
• Taken for less than 1 month
• June 3, 2021

Ondansetron for Nausea/Vomiting "I took Zofran on May 3, 2021, to help my nauseated stomach. After a little while when it kicked in, I started feeling very drowsy and tired, and my stomach seemed like it was hurting worse. I now know that this medication, Zofran, is not something for me to take. I want to get better, not worse."

• Tom...
• Taken for 1 to 2 years
• August 11, 2019

For Nausea/Vomiting "I have had severe abdominal pain, nausea, and fatigue for 3 years. I’ve had various specialized GI testing. I’ve had my gallbladder removed. Nothing has indicated the reason. Eating or avoiding specific foods did not make a difference. I started taking ondansetron 4 mg, as needed, with no positive result. I even upped the dose to 8 mg, per doctor's recommendation, but nothing. I tried other drugs, but the side effects would make me lethargic and would not allow me to do daily activities. Then my wife read a book discussing B12 deficiencies. My doctors were receptive and ordered blood work to test my levels. It was extremely low. I started B12 injections, and this brought my level up over a 10-month timeframe. I had tried the ondansetron again, and it worked temporarily, for a few hours, but not on a lasting basis. My doctor suggested a daily regimen of 4 mg three times a day. I started this 5 days ago. So far, it has helped enough so I can do daily activities again."

• Ott...
• Taken for less than 1 month
• July 8, 2022

Ondansetron for Nausea/Vomiting "I was given this for nausea from gastritis. It really didn't help the nausea, but it did give me a headache, made me very tired, that I had to lay down, and then gave me short, awful nightmares that I woke from with something like an electrical shock. It also made my breathing shallow, and like many, the next day I was very constipated. It was not a pleasant experience all around. I find non-prescription products much better than this for nausea. This made me feel much worse, and I would never use it again."

• Zof...
• October 29, 2022

Ondansetron for Nausea/Vomiting "Zofran had the opposite side effect on me, making me tired, nauseous with vomiting."