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Ondansetron and Nausea: What Users Say (Page 4)

Reviews for Ondansetron

Commonly mentioned side effects
  • Fai...
  • Taken for less than 1 month
  • December 4, 2021

Ondansetron for Nausea/Vomiting "Zofran made me feel worse and more nauseous rather than helping. I sincerely feel compassion for everyone that has experienced this from this medicine, and yet your doctor has not believed you or looked at you in disbelief, not having sincere compassion, empathy, and kindness when you know that taking it made you feel more nauseous immediately, throwing up as you combatted the watery feeling trying not to, and realizing the medicine made you feel worse instead of better. My daughter also was prescribed Zofran during a time that she was nauseous. I did not tell her initially of my prior experience taking Zofran because I realized medicines have different effects on different people. Of course, I was hoping it would help her and my daughter would feel better immediately or soon after taking it. She experienced the side effects that I did and told me adamantly she’s not taking any more Zofran! It made her feel more nauseous and worse instead of better. I understand."

1 / 10
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  • Ano...
  • April 11, 2018

Ondansetron for Nausea/Vomiting "Zofran helped greatly, went from vomiting constantly to nothing - it's amazing. The problem is that if you just take it, you will still vomit, you need to wait, and the nausea takes 10 minutes to stop."

9 / 10
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6 Report
  • Tls...
  • Taken for 6 months to 1 year
  • April 6, 2018

Ondansetron for Nausea/Vomiting "I get debilitating migraines that cause vomiting, and I have several GI issues. My doctor ordered Zofran pills to begin with, and they did nothing for me. Although I still feel a little nauseous at times, I can stop the vomiting with the Zofran ODT by putting it under my tongue."

8 / 10
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7 Report

Frequently asked questions

  • Cli...
  • July 27, 2014

For Nausea/Vomiting "I suffer from anxiety and panic disorder. My stomach suffers from my anxiety, and it seems that one triggers the other. After struggling for 3 days with constant nausea and running to the toilet, I decided to be brave and try one 4 mg wafer (I have a fear of any new medication). I made my husband drive into town, in case I had a reaction... so we were close to the hospital (I know... I'm crazy!!). Anyway, I took the little wafer, and within about 15 minutes started to feel better. Last night, I ate my first full meal in days, and this morning I feel fine. Next time, I won't wait as long! A great little pill to always have with you."

10 / 10
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  • Mal...
  • May 5, 2017

Ondansetron for Nausea/Vomiting "Was given Zofran tablets that dissolve a few months ago for the stomach flu, and it worked wonderfully. Now, they gave it to me in an IV, which worked for a few hours, but the tablets they sent home didn't help me with the nausea, only stopped the dry-heaving. Also, didn't last 8-12 hours, only lasted about 4."

3 / 10
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  • Dod...
  • January 4, 2017

For Nausea/Vomiting "I was prescribed Zofran 4 mg tablet after having a sucky bout of food poisoning, later turned IBS with chronic nausea. I have been on Zofran as needed ever since. Works great, if the nausea is really bad, I double up and feel great again. Another thing I found is if you take Zyrtec daily, it is great to use as a preventative and add the Zofran as a backup. Due to feeling like crap all the time with the IBS, I was taking too much Zofran, so my doctor recommended adding Zyrtec, which was a life changer. Instead of taking at least one Zofran a day, I'm down to once or twice a week, if at all. The tablets usually worked within 30 minutes. Was just switched to the ODT, so that'll be an interesting switch, supposedly they kick in faster."

9 / 10
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  • MHa...
  • April 4, 2017

Ondansetron for Nausea/Vomiting "I was given Zofran after having my gallbladder removed. The nausea wasn't from the procedure, but came on when I was finally able to eat and the broth soup was placed in front of me. For at least a month prior, I'd been getting nauseous just from seeing food no matter how hungry I was (and after fasting for surgery, I was absolutely starving!). I was given Zofran in my IV, and it did absolutely nothing. My surgeon then gave me a prescription for the pill form, but again, it did nothing to help my nausea."

1 / 10
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  • Deb...
  • May 21, 2014

For Nausea/Vomiting "My husband took me to the walk-in clinic with a severe headache and vomiting every 1/2 hr. A shot of this medicine stopped the nausea & vomiting almost instantly. I had a severe sinus infection, as it turns out."

9 / 10
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  • Ang...
  • Taken for less than 1 month
  • October 29, 2017

For Nausea/Vomiting "Most useless medication I’ve ever been on, I am taking it for severe morning sickness all day, and it has done nothing. I’m still vomiting and having nausea constantly. I don’t understand how this is supposed to work for someone going through chemotherapy when it doesn’t even help a pregnant woman the slightest."

1 / 10
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  • Sud...
  • Taken for 1 to 6 months
  • February 24, 2018

Ondansetron for Nausea/Vomiting "I have an extreme fear of nausea and vomiting. It’s so bad I get nauseated when someone coughs. I was given Zofran, and it was perfect for when my anxiety was making the fear harder to deal with. Then I got salmonella poisoning, and it didn’t work whatsoever. I took three 4 mg 20 minutes apart, hoping it’d help, and it didn’t. A few days after taking antibiotics for salmonella poisoning, I’m still a little nauseated (Zofran doesn’t work) and can’t do much. Thinking about going and getting a higher dose."

7 / 10
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  • Rig...
  • Taken for 5 to 10 years
  • March 17, 2022

For Nausea/Vomiting "Zofran has been a lifesaver for me! My multiple chronic illnesses have forced me to take a strong antibiotic every single day (2x a day) in order to somewhat manage my constant severe sinus infections (3 sinus surgeries in one year didn't even make a dent in the infections); the antibiotic has kept me from frequent hospital stays when it got so bad it traveled into my lungs. But that strong med comes with strong nausea and vomiting, so they put me on Zofran, and it almost instantly stopped it. I've been on Zofran 2x a day, EVERY day for almost 10 years, and it's made all the difference in the world for me. I actually take both the pill (to take with my antibiotic) as well as the disintegrating tablet for those times it comes on super quick. I have the 8mg pills, which I split in half, because there are times 4mg are enough and times when I need the 8mg. I'm so sorry for those who haven't had relief from this med and hope they're able to find something that does."

10 / 10
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  • woo...
  • Taken for 1 to 6 months
  • January 9, 2017

For Gastroenteritis "Originally, I was prescribed this med for the nausea accompanying irritable bowel syndrome because my nausea was debilitating. Zofran definitely took the edge off. Now I have gastritis, which causes nausea and pain. Unlike other patients, I do not get great relief. Sometimes it takes the edge off. Then I am able to eat and drink and be functional. But right now, the pain and nausea of the gastritis has trumped the med, I feel poorly."

6 / 10
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  • Mex...
  • June 3, 2016

For Gastroenteritis "I have a condition called gastroparesis, and for three years, I was in bed for 3 to 5 days a week, vomiting all day. I didn't have a life, it was slowly killing me. My doctor gave me every kind of medicine to try with no relief. Then she gave me Zofran, and it was a miracle for me! I take 8 mg, and I still will occasionally be nauseated, sometimes with vomiting, but as of now, it's been six weeks, and then it was only for a few hours. If anyone has suffered from this, it is horrible! I realize it may not work for everyone, but I was totally at the end of my rope, and this saved my life! I do have to take a laxative once in a while, but I'd rather do that than live the way I was!"

10 / 10
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  • Sza...
  • November 28, 2011

For Nausea/Vomiting, Postoperative "I had surgery, and the postoperative narcotics made me very nauseous, and I had to throw up. A full dose (8 mg) of ondansetron helped but did not fully resolve the problem. Then I got Phenergan, and all the nausea was finally gone. I think, for me, Phenergan is a better anti-nausea medication, but while ondansetron (Zofran) barely made me sleepy, Phenergan made me very sleepy. I actually think, if you are at home or in a hospital, it is much better to take Phenergan as it seems to help more and also gives you a good sleep. If you need to go to work or school, you should take Zofran."

8 / 10
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  • Vin...
  • Taken for 1 to 6 months
  • September 7, 2018

Ondansetron for Nausea/Vomiting "I take another drug that causes severe nausea. Zofran was prescribed; the nausea stopped, but the other side effects from Zofran were so overwhelming that I had to stop taking it. The side effects were diarrhea, headaches, blood in stool, dizziness, and yes, nausea. I couldn't drive, so I'll live with the nausea until I see my endocrinologist again and (maybe) he suggests something else. Bottom line: the side effects of Zofran outweigh the benefits."

4 / 10
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  • Abb...
  • Taken for less than 1 month
  • April 19, 2018

For Nausea/Vomiting "I had a really awful stomach flu that persisted for more than a week, so they prescribed me this, and it has been a lifesaver! I was originally taking the 4 mg, which wasn’t working quite as well, but the 8 mg makes a world of difference. It works so quickly and gets rid of my nausea and urge to vomit. Would definitely recommend!"

10 / 10
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  • KJa...
  • Taken for less than 1 month
  • June 9, 2018

For Nausea/Vomiting "It doesn't do ANYTHING for me. I took it while pregnant with hyperemesis and had to switch to Phenergan. I have some gastroenterological problems, and I'm finally going to see a gastroenterologist, but I've had horrific bouts of nausea and vomiting fairly regularly, and the Zofran did NOTHING. Still throwing up, still unbearably nauseous. Phenergan works much better, although oftentimes it stops me from vomiting, but the nausea is still there. Nonetheless, doctors always want to give out Zofran and almost act like you're a drug seeker when you ask for the Phenergan. I don't even drink or smoke, let alone take drugs, but it's the only thing that helps me when I'm stuck with the nausea and vomiting."

1 / 10
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  • Lit...
  • Taken for less than 1 month
  • December 12, 2016

Ondansetron for Nausea/Vomiting "I was rxed the ODT for extreme nausea and vomiting, due to a norovirus. The minty flavor really drove me over the edge and only made matters worse. Then my doc gave me the regular tablets that you swallow with a tiny bit of water, but it didn't help at all either. I remember being awed by the knowledge that they give this med to sick cancer patients when it is so horribly ineffective. Evidently, it does work like gangbusters for some people, but I'm not one of them."

1 / 10
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  • Iha...
  • Taken for less than 1 month
  • January 6, 2017

For Nausea/Vomiting "Came down with a very high fever and the flu. I had chills off and on for two days, which culminated with some good ole' vomit. Doc at urgent care prescribed me this horrific, useless drug for the nausea. I have NEVER had a poor reaction to any drug until now. Even with this drug, I felt extremely nauseous and had horrific headaches. I forced myself to throw up to relieve the debilitating feeling and stopped taking this drug and voila. I hate this drug. Never again. The headaches it induced brought me to the brink of tears."

1 / 10
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  • war...
  • June 18, 2013

For Nausea/Vomiting "I have a case of gastroparesis, and it stopped me from going to a lot of places and hanging out with my friends. It helps with the mild nausea really, really well, but when it gets severe, let's just say, it's useless! That's the reason why I gave it an 8, because when it's severe, that's when I really need it."

8 / 10
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  • Sir...
  • Taken for less than 1 month
  • October 14, 2016

For Nausea/Vomiting "I have suffered with hyperemesis with all my pregnancies. It's a horrible feeling not to be able to function at all. Zofran has worked wonders through an IV while at the ER. I've had it many, many times and it's worked. HOWEVER, the tablets do not work for me. They have never worked. For me, they make matters worse and make me feel more nauseous, they give me a horrible headache and back pains. I'm glad it's helped others, but it doesn't help me."

2 / 10
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  • And...
  • February 5, 2016

For Nausea/Vomiting "I sometimes suffer from anxiety that makes me physically ill. I have been nauseous and puking for 7 days, and I finally went to see a doc. They gave me the dissolving tablets. Eww! Gross. The taste stays in my mouth for hours, and it doesn't help. It just gets worse."

1 / 10
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  • Mic...
  • Taken for less than 1 month
  • December 3, 2014

For Nausea/Vomiting "I was in the hospital for 11 days, diagnosed with failing kidneys, which made me highly nauseated. I've lost 20 lbs. in 2 months. The shots worked quicker for me than the 4 mg pills I'm taking at home. But reading through the posts, I now know why I was severely constipated, and I normally suffer from irritable bowel syndrome...constant diarrhea. My kidneys continue to deteriorate, which causes the nausea. As far as the person who mentioned they stopped taking it because of a headache...the headache probably came from extreme vomiting or the blood pressure going up from the stress of vomiting. That's what happened to me. I would give it another try."

9 / 10
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  • Ale...
  • September 23, 2015

Ondansetron for Nausea/Vomiting "Sometimes have really terrible heartburn due to my birth control pills, and sometimes causes bad nausea. Wanted an alternative to promethazine. Works great for taming the nausea, but the side effects were pretty annoying. Terrible backache and constipation. Oh man. Won't be taking these unless I'm dying or something."

7 / 10
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  • Mig...
  • Taken for 2 to 5 years
  • October 3, 2019

For Nausea/Vomiting "The oral Zofran films (Zuplenz) are my lifesavers!! They are the only thing I can handle in my mouth when I'm nauseous from migraine, and they work like magic. I really don't know what I would do without them. I get 2-3 migraines a week, and they all start off with terrible nausea/vomiting. Zofran to the rescue!! Thank you to whoever invented it!"

10 / 10
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2 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.