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User Reviews for Nortriptyline

Also known as: Pamelor, Aventyl Hydrochloride

The following information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare practitioners.

Condition Avg. Rating Reviews Compare
Postherpetic Neuralgia 10.0
1 reviews 41 medications
Smoking Cessation 9.5
6 reviews 18 medications
Panic Disorder 8.5
6 reviews 19 medications
Irritable Bowel Syndrome 8.4
39 reviews 137 medications
Primary Nocturnal Enuresis 8.0
1 reviews 5 medications
Neuralgia 7.9
20 reviews 28 medications
Migraine Prevention 7.8
180 reviews 31 medications
Cyclic Vomiting Syndrome 7.3
7 reviews 4 medications
Vulvodynia 7.0
6 reviews 9 medications
Pain 6.8
106 reviews 1117 medications
Depression 6.4
51 reviews 81 medications
Neurosis 6.0
2 reviews 1 medications
Reflex Sympathetic Dystrophy Syndrome 3.7
4 reviews 2 medications
Diabetic Peripheral Neuropathy 3.3
4 reviews 42 medications
Dysautonomia 1.0
1 reviews 53 medications
Tinnitus 1.0
3 reviews 2 medications
Summary of Nortriptyline reviews 7.3 437 reviews

Reviews may be moderated or edited before publication to correct grammar and spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest in the medication will not be published. As reviews and ratings are subjective and self-reported, this information should not be used as the basis for any statistical analysis or scientific studies.

Reviews for Nortriptyline

rando · Taken for 1 to 6 months July 31, 2020

For Depression: “nortriptyline works great for TRD (treatment resistant depression). Gave me a break from the relentless nightmare I was experiencing. Seemed to not do much for anxiety at all, and maybe even make it a bit worse. Side effects were not fun though: inability to lose weight, softening of pecs, heart flutters, dry skin, migraines anything above 25mg, and brutal sun sensitivity. Like absurdly bad sun sensitivity. SPF100 to walk to the mailbox and back and still have red swollen cheeks twenty minutes later. Ultimately had to discontinue due to this as I can't sit in the dark forever. But worked better than any SSRIs/SNRIs by faaar.”

8 / 10
Nedrub · Taken for 2 to 5 years July 30, 2020

Pamelor (nortriptyline) for Depression: “I was 13 years when I started taking pamelor. My doctor and mother decided to put me on this medicine. I had a very bad experience with these pills. Whenever I had an episode They would up the dose, I started at 1-25mg tablet Every morning, within the year I was taking 5-25mg Tablet a day. Because of this I missed out on a lot of things. I was wondering around so much that I was getting lost, didn't know who I was, or where I was going, where I was supposed to be. I was just blah. Stuck in my thoughts and I hated every minute of it. But it was not my choice. I have nerve problem to this day, sometimes I get to shaking so bad that I drop anything in my hands, it's very hard to eat soup or drink coffee when I spill it all over myself. When I turned 18 it then was my choice, and I stopped taking them all together. A lot of my childhood was missed because of the pills, but on the flip side of it I didn't get beat for having an episode as much as I did when I wasn't taking them.”

2 / 10
Tasha · Taken for less than 1 month June 29, 2020

For Pain: “8 months of right-sided facial pain - burning, searing, shooting in the ear, cheek, temples and jaw due to possible never damage. Paracetamol and ibuprofen did absolutely nothing for the pain, after being prescribed a raft of antibiotics and other drugs like prednisone my doctor prescribed me amitriptyline which I noticed no difference in pain levels when taking. I then was prescribed nortriptyline 20mg and my pain level went to almost zero. I have been taking it for two weeks now and it feels so good at wake up in the morning pain-free and not like I have been hit by a truck. I don't notice any side effects as of yet.”

9 / 10
grateful_heart June 10, 2020

For Irritable Bowel Syndrome: “Honestly, this medication saved my life - it is a miracle. I have suffered with IBS for 10 years (am now 20) and it caused me to miss so much school. I started on 10mg of Amitrityptline in Dec 2019 and within a few weeks I had really terrible mental side effects. I became apathetic & had sustained low moods which were uncharacteristic. I switched to 10mg of Nortriptyline after 3 weeks and have been on the same dose since (it is now June 2020). It took exactly 3 weeks for me to start feeling a difference - but then after that, the improvement just got better and better. I now have almost no IBS issues! This medication won't, however, erase your food intolerances. If I go near dairy or fried chips, or have loads of large meals then I might still have a bit of trouble. But I went from having such a limited diet to now being able to eat almost anything, and it has made life so much easier. Alhamdullilah for this miracle drug, I seriously cannot recommend it highly enough :,)”

10 / 10
Skeezics · Taken for less than 1 month June 4, 2020

For Pain: “This was prescribed for my peripheral neuropathy. The doctor neglected to tell me that it was an antidepressant. Antidepressants have the opposite effect on me.”

1 / 10
Nica · Taken for 1 to 6 months May 16, 2020

For Irritable Bowel Syndrome: “This drug nortriptyline made me feel nothing. I didn't care about nothing much. It caused my boyfriend left and I didn't care at the time. Giving this drug for people with IBS its crazy. I would never again take anything like that. Before I realised it ruined my love life.”

1 / 10
Flutter · Taken for 1 to 2 years May 16, 2020

For Depression: “I had literally tried every SSRI and SNRI out there... 7 years of going through my nightmare of a life and nothing worked for my Treatment Resistant Depression. I was honestly considering ECT... I asked my psychiatrist if we could try a tricyclic in a last ditch effort... he put me on Nortriptyline a year ago. I'm now up to 100mg at bedtime, but this antidepressant has helped me more than anything had in 7 years, and no weight gain or bad side effects for me.”

10 / 10
ComradeWinston May 15, 2020

For Tinnitus: “I was taking Amitriptyline for a month and wondered if Nortriptyline would have less symptoms. Since Amitriptyline makes me constantly tired and reduces my sense of taste. So I talked to my doctor and was given 25mg capsules to take once a day. At first I felt a bit disoriented, almost as if it was the opposite of something like Adderall. But I wasn't tired all day and my taste buds returned to me in full so whatever, it seemed better the first few days. After nearly a week in, my tinnitus' screeching was becoming intolerably loud and made it harder and harder to fall asleep. Some days It would take more than an hour or maybe two simply to fall asleep. Within a few days it was becoming obvious not only made it worse. Also while my sense of taste wasn't changed, there was something about the taste of almost anything that wasn't satisfying. After two weeks, I went back on Ami. Amitriptyline might only help a bit but at least it does something to make tinnitus marginally more sufferable.”

1 / 10
Bike Monkey May 7, 2020

“Nortriptyline improves my sleep more than anything (physical exertion is the natural remedy but due to spine surgeries that has not always been an option) I digress... Nortriptyline doesn't knock me out but makes me a lil drowsy, which helps, but what is does for me that has improves my life is I am able to STAY asleep and if/when I wake to go to RR I am able to go back to sleep. Glorious! Seriously, for 20-25 years I struggled with sleep now it is decent to good, which I will take all day every day. Bike riding, waves, and Nortriptyline!”

10 / 10
Eric G · Taken for 1 to 6 months April 21, 2020

For Depression: “I was getting ECT treatment for depression when my doctor told me Nortriptyline pairs well with the ECT therapy. I once had a bad reaction to Trintillex . Without having much recollection of why I decided to start this new med I did. I felt ECT was starting to heal my depression. As a few weeks passed, I noticed major daytime fatigue. Also EVERY night I would experience irrational fear and panic, also had a few panic attacks at night which has not happened for me in years. Constipation , vomiting , worsening depression, thoughts of self harm . It took me way too long to figure out nortriptyline was the culprit of all this. I was on this medicine for about two months and am in the process of weaning off. If you notice similar symptoms speak up to your doctor ASAP.”

1 / 10
Cml · Taken for less than 1 month March 31, 2020

For Depression: “I was put on Nortriptyline for my depression and anxiety, but up to now it did not help yet. The only thing it does help with is sleep, 30 minutes after my dose I get extremely tired and get knocked out, and after 10 hours of deep sleep I wake up still very tired. Also very hard to get orgasm which is a frustrating side effect. Which I never experienced with any SSRI. Phenelzine also has this side effect but less than Nortriptyline If it wont give me any relief in 2 weeks for my depression and anxiety my doctor will put back to Nardil / Phenelzine 90mg, This has very few side effects and at least gives decent positive effect.”

3 / 10
Violet5401 · Taken for 1 to 2 years February 18, 2020

Pamelor (nortriptyline) for Depression: “I had been taking Trintellix for a couple years with success until eventually my anxiety/depression started to creep back. My doctor added 75 mg of nortriptyline every day and I swear I felt major relief in just 3 days. I have been on the Trintellix/Pamelor combo now for over a year. No side effects, and the Pamelor is cheap. As an added bonus, I have chronic hip pain due to bursitis and the pain has almost completely gone away. I am so thankful for this medicine, it has truly helped me.”

10 / 10
PH · Taken for 2 to 5 years February 16, 2020

For Depression: “I have been on nortriptyline for 2.5 years due to anxiety and it has significantly improved my quality of life. I do have dry mouth as a side effect but it is very worth it in comparison to the benefits that it brings. Prior to starting nortriptyline I experienced a number of secondary symptoms caused by my anxiety: insomnia, headaches, and loss of appetite. In addition to reducing my anxiety, I now sleep well every night, no longer have frequent headaches, and I have an appetite that allows me to keep my weight at a healthy spot (I was too thin before). These things seem to help my immune system too because I seem to be much better at fighting off/avoiding colds than before I was on this medication. So in summary: This medication helped address my anxiety and a bunch of secondary symptoms that I hadn’t realized were anxiety related. On this medication I feel happier and healthier than ever before.”

10 / 10
Harlow · Taken for 6 months to 1 year February 6, 2020

For Migraine Prevention: “I have been taking nortriptyline to help stop getting migraines, been on it for about 6 months now and it has completely changed my life. I used to get migraines 3-5 times a week and they were unbearable. I do still get migraines but maybe only a handful of times a month. I also take it for anxiety and it has seemed to help quite a bit with that too.”

9 / 10
T February 5, 2020

For Depression: “I have been taking this medication nortriptyline for the past four years. It has cured my depression and also helps me sleep better. Best decision I’ve ever made.”

10 / 10
Bird January 22, 2020

For Pain: “I don't remember having nightmares on Pamelor or Elavil. Both worked well for migraine/facial nerve pain & depression. They'd be better if the side effects weren't dry mouth, constipation, dizziness & lethargy (Elavil). Remeron is a different story. I had the scariest, most traumatic dreams ever. I was so terrified after waking up, I told my doctor I could not take it anymore. Pamelor & Elavil are probably the best antidepressant that I have tried other than Effexor & Wellbutrin- although the latter gives me more side effects. SSRI'S don't work for me & cause agitation, insomnia, teeth grinding. I'll stick with the older antidepressants or the SNRI'S.”

9 / 10
Sv · Taken for less than 1 month January 8, 2020

For Migraine Prevention: “I was only able to try this drug for 3 days because I couldn’t handle the side effects. The dry mouth I could handle, but not the hot flash- I'd feel pressure and tightness around my body then start sweating from hands and my feet. I also had insomnia from this! Could not sleep at all. Felt so awake throughout the night. Only reason why I'd end up falling asleep is because I’m so so tired. But would still wake up in the middle of the night and feel awake. On one of the days, I woke up with a headache from this med. I wish I would’ve worked for me for my headaches, because I tried so many drugs already but they never worked for me! (Tizanidine, baclofen, cyclobenzaprine). My doctor wants me to try venlafaxine next but from reading the reviews I’m discouraged.. This drug also wasn’t too pricy.”

3 / 10
Anonymous · Taken for 1 to 2 years December 10, 2019

For Migraine Prevention: “My doctor prescribed me a 25mg dose of Nortriptyline after having severe migraines every week since the 8th grade. 7 years later, I am finally able to go to work and not worry about vomiting from my head aches. I’ve been on it about 2 years and I’m not sure if my memory was this terrible before, but I’d say the pros outweigh the cons. Also topamax worked for me as well but caused me to have severe anger issues.”

8 / 10
Skaz December 9, 2019

For Pain: “I’ve been dealing with chronic pain in my back for about 6 or 7 years. I’m 22 years old and I’ve been to lots of drs and specialist to find out what’s going on. Let’s just say nobody knows what’s causing it. I’m 22 years old and feel like I’m in my 60s can hardly get out of bed some days or even weeks. Two drs recommended this med for me and I refused to take it. My mindset is it is mainly used for depression. But at the low does they gave me it was for pain. After some research and being stuck in bed hardly able to move I reached a point of I have nothing to lose In my life. I’ve taken nortriptyline for a few days now and it has helped wonders. I stopped for a day to see if what’s happen and yep pain returned. Hope now I can just take the meds and go to the gym to lose the weight and hopefully that’ll help too. My grandma was prescribed this and it didn’t help her. But for me it has. So everyone’s body is different just remember that.”

8 / 10
Moomoo · Taken for less than 1 month November 17, 2019

For Pain: “Given these nortriptyline at a dose 10mg per night for chronic osteoarthritis pain in hips knees and wrists. Have been taking them for a week and they have done nothing. Don't know whether to ask Doctor to increase the dose or ask for something else. They were supposed to aid sleep. But I'm still awake most of the night in agony. I also take Tramadol but as I've been on those for 4 years the effect has worn off. Oh for a decent sleep.”

1 / 10
TCA Enthusiast November 17, 2019

For Depression: “This was super-effective for both severe treatment resistant depression, anxiety, chronic vestibular migraines, panic attacks and even helped a bit with social anxiety and OCD. Never had such remarkable effects from any other drug before, even with SSRIs/SNRIs(which made depression worse) and MAOIs. I started feeling better the very first day and within a few days I had old emotions back that I hadn't experienced in years. Unfortunately I developed a drug allergy to this drug, but it is not the drug's fault but my immune system. The drug still gets a 10/10, and I will be trying another TCA soon hoping it works just as well! Also don't worry about the anticholinergic effects of this medicine/other TCAs the anticholinergic side-effects of this medicine can actually be of benefit in treating your depression and should rather be called "effects" than "side-effects" and embraced and accepted as being potentially positive.”

10 / 10
Queen · Taken for 1 to 6 months November 2, 2019

For Neuralgia: “I have chronic back and nerve pain. This medicine nortriptyline curtailed my nerve pain and back itching that made it difficult to sleep. Also assisted with longer, deeper sleep.”

10 / 10
Flip · Taken for 1 to 6 months October 28, 2019

For Irritable Bowel Syndrome: “I have had IBS with gut pain for 35 years. Two years ago I became intolerant of wheat and dairy and developed IBS D. I tried Nortriptyline at 10mg which didn't help with the pain or diarrhea. I then moved on to 20mg and have been on it for 2 months with less frequent diarrhea but still with pain. I've just decided to come off it now. The biggest improvement in my IBS symptoms was using probiotic, which I think I will start again.”

1 / 10
Happikampa · Taken for 1 to 2 years October 24, 2019

For Pain: “After 7 years of chronic pain in my lower back and stabbing/burning pain in my glute, I was finally prescribed Nortriptiline. I waited two weeks to start it as Pregabalin had been so horrible. After one dose I finally was able to sleep for 7 hours. Had been sleeping for about 4 hrs a night up until then because of the pain which didn't respond to Ibuprophen, Paracetamol or Opioid based medication. Pain relief lasts for about 17 hours. No side effects other than I do feel a bit sleepy at times. Still take Ibubrophen if I have over done the gardening or house work. Now it works to help me sleep. Dose is 20mg a night.”

10 / 10
Janine · Taken for 5 to 10 years September 26, 2019

For Panic Disorder: “This medicine nortriptyline saved my life. Back in 2013 I woke up with panic attacks and anxiety through the roof. I had to end up going on disability twice and none of the regular depressants/anxiety medications would help. Found an amazing psychiatrist who put me on this life-changing medication. I am on 125 mg a day and it completely got rid of my anxiety and depression. No more panic attacks. I do take Ativan just in case I feel the anxiety coming on strong however the nortriptyline really helps control it. I recommend this medication to anybody with anxiety/panic/depression. You do need to give it time. The first time I was on it within two months I was cured I did get off it for a while to see if I needed it and I sure did. When I got back on it the second time it took six months to work. Be patient.”

10 / 10