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Nortriptyline User Reviews & Ratings (Page 4)

Brand names: Pamelor

Nortriptyline has an average rating of 7.3 out of 10 from a total of 572 reviews on Drugs.com. 69% of reviewers reported a positive experience, while 20% reported a negative experience.

Reviews for Nortriptyline

Commonly mentioned side effects
  • Pat...
  • March 19, 2013

Nortriptyline for Migraine Prevention "I have been taking Pamelor for close to 4 years now. After a coiling procedure for an inoperable brain aneurysm, I suffered constant migraines. The doctor who performed the coiling did not offer any solution, but a local neurologist in my hometown prescribed it for me. It changed what was to be my new life of pain into a much more tolerable existence. A little dizziness is easy to live with. I take 50 mg every morning. Life is good again!"

10 / 10
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  • CJC...
  • November 15, 2015

For Migraine Prevention "I never write reviews but for this drug I feel like I have to! I have tried so many drugs, herbal supplements, chiropractor, massage, acupuncture etc. have been hospitalized before for my migraines, and at some periods had them every day. I thought if this is the reality of my life being in pain every day, what is the point? This is the only drug which works and has almost no side effects except for at first a dry, nasty tasting mouth which has gone away for the most part. It took a couple of days to kick in and I'm on a very low dose of 10 mg which I take at night. It's been almost a week pain-free! I feel like a new person and it finally feels like the miracle I've been looking for, so don't give up!"

10 / 10
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  • Rob...
  • August 13, 2015

For Panic Disorder "Had a few panic attacks, which later led to constant panic attacks. This caused Agoraphobia. Suffered for 3 years and nortriptyline cured me from them 100%. Stopped the doom and the attacks. I was on it for 3 years and all was perfect. Later, I tried many SSRIs and all of them seemed to induce or create panic attacks. When I stopped the SSRIs, they went away. I have been free from panic attacks since. It has now been 10 years clear. Thank you, nortriptyline."

10 / 10
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Frequently asked questions

  • Reg...
  • Taken for less than 1 month
  • December 31, 2015

For Pain "I have Myofascial pain syndrome and median nerve entrapment that makes my fingers numb with tingling sensation. I have a very bad pain on my left scapula that radiates down to my lower back and travels to my left arm down to my fingers - the pain that I cannot explain at all, it disrupts the quality of my life. I thought there's no hope for my pain to go away. My doctor tried some other pain medication including neural injection. After taking the 3rd dose of nortriptyline 10mg, I can see the difference - my pain is dull and episodic but tolerable. Everyone is different but there's no harm in trying if we are concerned about side effects, all medications have side effects anyway. I recommend to those who are suffering from pain to try this."

9 / 10
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  • Tho...
  • February 19, 2017

For Depression "I suffered from depression and anxiety at a young age due to a stuttering problem, but I never knew at that time what caused it. I went to a doctor at the age of 22, and he put me on Pamelor. I was afraid to take it, but I did. The first few days it made me feel weird. I felt like a zombie at first for maybe 3 days, but then it went away. In 6 weeks, my depression was gone, and I felt like a normal person. I was normal. I think my dose at one point was 100, which is moderate. People need to know that this type of medication takes 6-8 weeks to work, and when it does, it's like a fog has lifted, for me at least. You have to be careful with weight gain because it does increase your appetite. It helped me sleep at night. 6-8 weeks to work."

10 / 10
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  • Vib...
  • October 30, 2015

For Pain "I started at 10 mg at bedtime for pain in my lower back. The pain would go down both legs and was ruining my life. After a few weeks, I was up to 60 mg, and I am virtually pain-free. I am sleeping great, too. The dry mouth usually comes for me after I up the dose. One thing though, I had a numb spot right above my right knee, which is caused by a pinched nerve in my pelvic region. The numbness has turned to a fullness in my knee now... weird but I can live with it."

10 / 10
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  • Mou...
  • Taken for 1 to 6 months
  • December 21, 2017

For Irritable Bowel Syndrome "I HAD UNRELENTING DIARRHEA AND COULD NOT LEAVE THE HOUSE WITHOUT TAKING IMMODIUM. My doctor prescribed nortriptyline. I filled the prescription but did not take it because, well, I almost thought it was foolish. I was not depressed... But then I thought, what the heck. I started the 10 mg every night. In 3 days, the only side effect was no more running to the bathroom. OMG, for me, it is a miracle. I do have vivid dreams, but that is okay. Also, I sleep well and feel great when I wake up."

9 / 10
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  • JZ6...
  • March 7, 2013

For Irritable Bowel Syndrome "This medication has been a lifesaver. I am a 23-year-old female and was diagnosed with Irritable Bowel Syndrome 10 years ago. It wasn't until 2 years ago that my primary care doctor suggested this medication after finding success with another patient. Only 10 mg a day at bedtime and I am IBS symptom-free. I used to have 5 bowel movements a day and now I am very regular. My life is so different now that I am on this medication. When I started the medication, I had extreme dry mouth that went away after a couple of months and now I sometimes become constipated (which is something I've never had in my life)."

10 / 10
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  • pam...
  • September 26, 2013

For Migraine Prevention "I was prescribed this medication because my migraines were increasing and my sleep was getting very erratic. Since taking this medication for the past month, I have slept through the night and it is easy for me to fall back asleep if I wake up to use the bathroom. I am so glad my doctor suggested this. After 13+ years of bad sleep and an increase of migraines, I think I found something that works without any side effects (thus far). I take about 1 hour before bed and it has worked like a charm."

9 / 10
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  • Jea...
  • Taken for 5 to 10 years
  • April 2, 2024

For Depression "I had suffered with depression and addiction my whole life because I was self-medicating. I was officially diagnosed with postpartum depression after my second child, and after trying a couple of other medications, I was put on Nortriptyline. At first, every time my dose was increased, I would feel off, almost sick, for a day or two, but after that, all balanced out. I can’t tell you how much of a life changer this medication has been. It’s not that I never get sad, it’s that I never fall into that deep, dark pit anymore. People with depression know what I mean. I feel like what I think a ‘normal’ person feels like. I’ve been on it for 6 years. Life is not perfect, but it is so much better. If I could meet the creators of this, I would give them a big hug."

10 / 10
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  • Anonymous
  • January 13, 2014

For Migraine Prevention "I'm a 47-year-old male who has suffered from migraines for about 30 years. They have increased in frequency and duration over the last 2 years to the point where I sought preventive therapy. I tried propranolol, various muscle relaxers, and most recently nortriptyline. I started with 10mg taken at bedtime with little relief. Eventually, increased dose to 75mg and am happy to report migraines have decreased from 2-3 a week to 2 a month. Still have to stay away from triggers such as alcohol and chocolate. Only side effect seems to be short-term memory loss."

8 / 10
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  • Anonymous
  • March 25, 2011

For Depression "After some serious life events I became depressed - while I didn't truly realize it - my house became overly cluttered, work went from great to average, got behind on things... after attempts at Lexapro, we figured out that I was having a reaction to the Lexapro. We started on nortriptyline. The first winter I worked up to 75mg/day - then went off for a few months during the summer - this year I've worked from 25mg then to 50mg/day. It's amazing how much better I'm performing. I do have issues with the drowsiness but I try to work through that. Work is now improving after about 14 months of treatment and the home is slowly getting better."

9 / 10
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  • ell...
  • April 14, 2013

For Pain "Was diagnosed with somatic pain. Prescribed 10mg nortriptyline to start. Took one pill and it made me feel like I could jump off a building and fly. When I laid down, it felt like I was floating. Went to sleep, woke up feeling like a zombie, very depressed, could barely lift my arms. It has been three days and I still feel spaced out."

1 / 10
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  • Eri...
  • Taken for 6 months to 1 year
  • May 14, 2016

For Pain "Took this for nerve pain and it helped! Except I would rather ache & have nerve pain than deal with the side effects I experienced. I kept getting nightmares that were so horrific, I eventually started sleeping with the lights on & thus not sleeping as good. Within 6 months, I gained 20 lbs without changing my eating habits nor physical activity. Looking back, there was a short period of time when my vision was affected as I had trouble focusing. At the time, I just thought my contacts prescription was getting too strong for me. I decided to revisit the list of side effects and sure enough there they all were. I quit taking nortriptyline that day and eventually the nightmares, blurred vision, & weight gain went away."

3 / 10
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  • Les...
  • Taken for 6 months to 1 year
  • September 21, 2024

For Depression "I’ve taken nortriptyline for 10 months. I was a bit pessimistic about taking it because of the many failures I’ve had with other meds. Still, I realized that my mental health was truly at a low point. So I tried the nortriptyline and became amazed at how much better I felt. I started falling asleep quickly and feeling fresh. I am truly so thankful, as I feel content, at peace, and I actually feel joy. I’ve never felt this way. It’s miraculous for me. I suggest giving nortriptyline a try and giving it time to assess its effectiveness. I no longer feel the aspects of depression or anxiety that had plagued me. I also have no weight gain, tiredness, emotional blunting, or sexual side effects. The only side effects I have are a drier mouth, which is simple to remedy, and a quicker heart rate (that’s modest and I’m not aware of it and not a concern for my doctors). I will be taking it for life! It’s a miracle for me that’s helped my IBD, NDPH, sleep, depression, and anxiety."

10 / 10
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  • bir...
  • October 17, 2010

Nortriptyline for Migraine Prevention "I've suffered from migraines for 14 years and have taken numerous medications for prevention including Topamax. Topamax caused MANY bad, undetermined health issues. My Internal Medicine physician took me off Topamax and put me on 25 mg of Nortriptyline for migraine prevention. Almost immediately, I had relief from migraines, had clarity of mind even better than ever before, had a great attitude. I felt 'normal' for the first time in my life. This medication caused noticeable urinary retention, constipation, and increased appetite which caused weight gain. Due to weight gain, I was changed to Pristiq. Migraines have returned. I intend to ask to be put back on Nortriptyline and will have to alter diet and exercise."

10 / 10
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  • whi...
  • March 2, 2014

For Pain "I was prescribed this to help with my back pain after nearly everything else failed, and amitriptyline made me like a zombie. Regrettably, it has had very little effect on my back pain, and it doesn't really help with sleeping, however, it has worked wonders for the horrendous 'nerve end' sensitivity I was experiencing, meaning I couldn't allow my dogs to sit alongside me, never mind touching me."

6 / 10
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  • gt8...
  • April 2, 2016

For Irritable Bowel Syndrome "Had stomach pain for years. When I ate, my stomach would hurt for hours. When it finally calmed down, it was time to eat again. Went to a gastroenterologist. Had a colonoscopy, endoscopy, and biopsies. Everything looked alright. Was having awful pain one day and called my gastro doctor for an appointment. He could not see me for weeks, but I was told his nurse could. I was hesitant, but did go in to see her the next day. She prescribed 10 mg of Pamelor at bedtime (name brand for nortriptyline). She said it was an antidepressant but had been found to help many issues. After taking it for 3 nights, I felt like a new person. When I went back for a follow-up, I hugged my nurse and said, 'You gave me back my life.'"

10 / 10
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  • Lia...
  • Taken for 2 to 5 years
  • March 10, 2014

For Migraine Prevention "I'm a disabled vet due to migraines and have been on many medicines to both prevent and treat. I have Botox injections every 90 days and a constant supply of Imitrex injections to which I take approximately 8 times a month. I notice a HUGE difference when taking the nortriptyline (75mg at night). I love that it helps me sleep. I just can't forget to take it, if I do, hello migraine."

10 / 10
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  • Anonymous
  • March 28, 2012

For Depression "I suffer from depression, back pain, and anxiety that has been gradually getting worse. I started taking nortriptyline and noticed a number of changes within 24 hours. I finally slept through the night. My back pain dramatically improved, and my anxiety lessened. Sounds amazing, right? Well, yes, but I was also crying all the time and felt even more depressed. I also began having bad thoughts about hurting myself. I have had bad thoughts in the past, but always had control of them. These felt very different, I had no control of them. For some people, this medicine is a miracle, but if you start to have thoughts that don't feel right when you start taking this medication, go to your doctor immediately."

5 / 10
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  • Anonymous
  • March 5, 2012

For Neuralgia "For the last 10 years my fibromyalgia has gone downhill. This medicine has given me some of my life back. I had horrible pain in my neck and back, fatigue, not sleeping, migraines, nervous stomach, and several other problems. I was run through a battery of tests and no one could figure out why I was having all these problems. Finally, a doctor said it sounded like fibromyalgia. I was put on a small dose of nortriptyline (20mg) and within a week, I was feeling somewhat better. Within 2 weeks, I felt almost normal again. This medicine has changed my life. I can finally do the things I used to do. I still get migraines and sometimes feel unwell again, but it's not very often. I do get dry mouth a lot, but I can deal with that over feeling sick."

10 / 10
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  • 2Re...
  • Taken for 5 to 10 years
  • January 13, 2016

For Migraine Prevention "I've had migraines since I was 9. My parents weren't big on doctors, so I 'bucked up' through the raging pain. I didn't know until my 20s that having headaches every day wasn't normal. When I got married and my husband found me curled in a ball of pain, he didn't take 'I'm okay' for an answer and took me to his family GP. The first day I took Nortriptyline, my migraines vanished. I didn't even know life could be so pain-free! It's been 8 years now, and I'll happily take it forever to be free from the wracking pain. If I stop, they come back and remind me to get my refill. It has worked wonders for me."

10 / 10
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86 Report
  • Liv...
  • Taken for less than 1 month
  • December 6, 2018

For Migraine Prevention "Be careful with this medication if you have struggled with depression or have a family history of mental illness, depression, bipolar, etc. I went on this for migraine prevention, not for depression, and on my second day of taking it, started having really dark thoughts and hit a real low point. I have never been suicidal before and am actually usually the happiest I have ever been, but this medication completely distorted my perception of things. Had to go off it a week later as the feelings only got worse."

1 / 10
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  • Bax...
  • Taken for 1 to 6 months
  • August 12, 2019

For Pain "I have been struggling with progressively worsening nerve pain for 10 years. I cannot lift up on my toes on either leg due to nerve damage (slipped disc on one leg and some kind of impact arthritis on the other). The nortriptyline has virtually eliminated the nerve pain! I've been taking 25 mg for one month. The so-called 'side effects' are virtually all positive. Constipation? Great! Now I can have just one bowel movement per day instead of 5 or 6. Sleepiness? Great, I sleep much better now! I used to take a half dozen ibuprofen and acetaminophen and 2 naproxen almost every day... now one ibuprofen some mornings and that's all I need. Cannot say enough good things about this product!"

8 / 10
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  • sta...
  • June 5, 2010

For Pain "I am still in the early stages of using this medication. My fourth week. It has really helped with the back pain. Although I still feel pain, it is not continuous in all areas of my back. It is now just if I tweak the source. I did not heed the warning to avoid alcohol the first week and was very ill as a consequence. I was vomiting for 2 days afterwards and very dehydrated. My own fault. I am going to speak to my doctor to see if we should add to the dosage to try and get rid of the pain completely. I am currently on 10mg per night. Although I don't drink much, I do feel that I don't have the freedom to choose if I would like to drink. So, this is the down side to this medication. However, I would love to get rid of back pain for good!"

7 / 10
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127 Report

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