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Nortriptyline User Reviews & Ratings (Page 2)

Brand names: Pamelor

Nortriptyline has an average rating of 7.3 out of 10 from a total of 567 reviews on Drugs.com. 69% of reviewers reported a positive experience, while 19% reported a negative experience.

Reviews for Nortriptyline

Commonly mentioned side effects
  • Mad...
  • February 11, 2013

For Pain "I had a car accident two and a half years ago. It damaged my shoulder and gave me severe back pain. Last year, I eventually had an operation to resolve the problem of a chipped bone and a release, but it did not help me with the constant stabbing pain which I was told was my nerve and tendons being in a knot. After numerous attempts through physiotherapy, massages, painkillers, and injections, none of them worked until I was prescribed nortriptyline. What a difference, I am hardly in any pain now and feel much better."

8 / 10
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  • Anonymous
  • September 6, 2011

For Pain "I have suffered with Fibromyalgia for nearly 25 years. This is the only medication that helped with my pain; helped with sleep and did not make me feel 'dopey' all day. I can't say it will work for everyone, but it has helped me. I have been on it for 20 years. I take 50mg at night about an hour before bed. When there are weather changes coming through, my pain gets worse, I take 60mg."

8 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • September 21, 2012

For Pain "After 6 months of constant agony due to four herniated discs in my neck, my doctor finally got it right. The starter packet started me out on one pill a night and could have gone as far as five. Happily, two have done the trick. I am so relieved. I was beginning to think I'd never feel pain-free again. It is a miracle."

10 / 10
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Frequently asked questions

  • Deb...
  • April 25, 2017

For Depression "I'm 61 years old and have been taking Nortriptyline for about 30 years for depression. I believe I was depressed most of my life before being diagnosed. Initially, it took about 4 weeks before I started feeling the effects of the drug, but once it kicked in, it made all the difference in the world. After many years, my doctor had me try some of the newer SSRI drugs (while still on Nortriptyline) and with each one, I didn't feel at all like myself (like I was watching my life from outside myself), so with each attempt at trying a new drug, I kept going back to what worked best: Nortriptyline. I guess I'd consider myself a poster child for the drug because it's always given me a level mood, and I've never experienced deep depression while on it."

10 / 10
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  • Anonymous
  • November 1, 2012

For Pain "I have been on this medication now for 6 months for nerve pain and tingling down my leg from a trapped nerve in my back. 10 mg at night along with other Paracetamol and Ibuprofen certainly does relieve the pain. I was told to increase the nortriptyline as required to 20 mg at night if necessary but so far I have not had to do that. Side effects have been virtually non-existent against the benefit of it."

8 / 10
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186 Report

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  • Ano...
  • Taken for 1 to 6 months
  • April 27, 2014

For Migraine Prevention "10 mg at night for chronic tension headaches. The first few days were horrible: extremely fatigued, grumpy, felt like a really bad hangover. But by the fourth or fifth day, all of that was gone, and my headaches went too. I'm glad I stuck it out, because I had had headaches that interfered with my daily life. It made me very drowsy at first, and still does act as a bit of a sedative, so I only take it if I plan to sleep very soon. Also, it really lowered my alcohol tolerance, so watch out for that."

9 / 10
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  • Kda...
  • Taken for 1 to 2 years
  • March 22, 2019

For Migraine Prevention "My headaches were non-stop for about 3 years. The cause was my neck. I had already had neck surgery about 8 years before. So, I was told they said I was not a candidate for surgery anymore. So I tried cortisone shots, and some other shots and nothing. Then the doctor came up with nortriptyline 10 mg, a dose of 2 pills a night. Well, by the third night, I slept like a baby. Before, since my headaches were NON-STOP, it meant I could not sleep at all! After a week, I had no headaches and I could finally sleep!"

10 / 10
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  • Tan...
  • Taken for 5 to 10 years
  • July 6, 2018

For Depression "This medication saved my life. I originally tried amitriptyline. I felt tired and still didn’t fully rid the black cloud over me. I tried this on the recommendation from a neurologist. Best decision I ever made. I am now the person I used to be before I became depressed. I am so thankful for this medication. 50 milligrams a night is my dose. Forever thankful I tried this medication :)"

10 / 10
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  • 16a...
  • July 26, 2016

For Pain "I am currently 16 years old and have been taking nortriptyline for about 6 years to treat migraines. I have been getting migraines since I was 8 or 9, and it eventually got to the point where migraines were a daily thing for me. After seeing a neurologist and trying out 2 or 3 other prescriptions, my neurologist prescribed nortriptyline. It worked for a while, then my dosage needed to be increased. However, I still take it to this day, once before bed every single night. The only time I get a migraine now is if I'm sick, skip two or more doses, or encounter a trigger, such as prolonged sun exposure, dehydration, large caffeine amounts, etc."

10 / 10
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  • Rhn...
  • April 30, 2014

For Migraine Prevention "I just turned 40 and have suffered from migraines with aura with increasing frequency and severity since I was 16. In March 2014, I was up to 18 migraines in 22 days. My doctor took me off all the Triptans I was taking and never worked, to my great relief! At first, I tried a blood pressure med, but after 2 weeks of horrible side effects (horrible depression, weight gain, insomnia), my GP put me on Nortriptyline. I have been on it for 4 weeks. We started with 10 mg at night. I noticed that the pain from my migraines and frequency reduced by about 50%, and Advil liquid gels were able to take the pain away. I have now been bumped up to 20 mg. I haven't noticed dry mouth, but I did notice my eyes get dry. I sleep really well. No other effects."

9 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • June 12, 2019

For Irritable Bowel Syndrome "After years of suffering with IBS-D, I ended up seeing a brand new doctor at the Polyclinic. He started off treatment by eliminating all of the scary stuff - I had an endoscopy, colonoscopy, gastric emptying study, blood work, etc. When all results came back normal, he decided to treat the IBS symptoms with Nortriptyline (25 mg per night) and the low FODMAP diet. I am thrilled to say that my symptoms have finally subsided, at least enough to where I can live my life and eat comfortably. Although I wouldn’t say I’m completely symptom-free, I feel significantly better. I’m not sure if it was this medicine or the low FODMAP diet that worked best, however I will continue to do both and slowly add foods back in. Definitely try this out if it is recommended for you! This is coming from someone who suffered for 6+ years and has tried every diet, supplement, and medication known to man."

8 / 10
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  • Har...
  • Taken for 6 months to 1 year
  • February 6, 2020

For Migraine Prevention "I have been taking nortriptyline to help stop getting migraines. Been on it for about 6 months now, and it has completely changed my life. I used to get migraines 3-5 times a week, and they were unbearable. I do still get migraines, but maybe only a handful of times a month. I also take it for anxiety, and it has seemed to help quite a bit with that too."

9 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • October 12, 2012

Nortriptyline for Pain "I have calf pain (mainly when sitting) due to small fiber neuropathy. I tried Neurontin, Lyrica, Cymbalta...without any luck. Tramadol provided limited relief, but not nearly enough. Finally, I tried Pamelor and after a few weeks, the calf pain started to dissipate. I take 100mg/day, and the side effects have been pretty mild. The drowsiness tapered off after a few days, but the dry mouth and constipation go with the territory. I get occasional tinnitus as well."

8 / 10
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  • ano...
  • January 31, 2016

For Pain "I suffered severe depression for more than 10 years. I have been recently diagnosed with Fibromuscular dysplasia. One of the effects of this condition is terrible migraines, lightheadedness, insomnia, and dizziness. I was unable to function on a daily basis, feeling sleepy at work and miserable. I could not thank my neurologist enough. He stopped me from taking any other antidepressants and put me on this drug. After 15 days, I can notice the difference. I am not sleepy during the day, I am able to function, headaches are gone, and I am able to sleep straight for 7-8 hours. My doctor told me, though, that this medication will make me gain weight. I'm preventing this by eating healthier and trying to exercise 3 times a week, and it's working."

10 / 10
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  • Sea...
  • February 21, 2012

For Panic Disorder "Have had GAD (Anxiety, sometimes severe) on and off for about 12 years. I'm a 58-year-old male in excellent health, otherwise. Nortriptyline was the 7th med prescribed (after Lexapro, Beta Blockers, Zoloft, etc.) and for me, it was radically better than all the other meds. Tried to take at night but was too activating. Started taking 10 mg in the AM and another 10 mg in the afternoon (if needed). Completely controlled my anxiety, gave me more energy, improved sex drive, and cleared up both acne & rosacea. EXCELLENT drug...worth a try. Due to the low dose, I had none of the typical side effects (dry mouth, etc.)"

9 / 10
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  • Mik...
  • April 10, 2017

For Pain "Have suffered with back pain for 22 years. I'm 60 years old now. Started taking nortriptyline 4 days ago. While I know that's not very long, I can say back pain is much better. Depression is much better. Overall feeling is much better. Sleeping better and longer. I have noticed some drowsiness but not a lot. I hope things continue in the direction I'm currently headed. Good luck!"

10 / 10
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  • Vio...
  • Taken for 1 to 2 years
  • February 18, 2020

Nortriptyline for Depression "I had been taking Trintellix for a couple years with success until eventually my anxiety/depression started to creep back. My doctor added 75 mg of nortriptyline every day and I swear I felt major relief in just 3 days. I have been on the Trintellix/Pamelor combo now for over a year. No side effects, and the Pamelor is cheap. As an added bonus, I have chronic hip pain due to bursitis and the pain has almost completely gone away. I am so thankful for this medicine, it has truly helped me."

10 / 10
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  • Mad...
  • Taken for less than 1 month
  • February 13, 2016

For Pain "I've never felt so angry in my life than on this drug! Terrible! Frustrating because doctors won't prescribe my OxyContin I've been on for 9 years (that completely helped my back after 3 failed surgeries) anymore because of all the irresponsible people abusing it! HOW IS THAT FAIR!? So annoyed that people who really need it have to pay the price! So I've been trying all this junk that has terrible side effects."

1 / 10
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  • Hol...
  • Taken for 2 to 5 years
  • February 23, 2017

For Pain "Been using this drug for 2 years. I used to have bad pain in lower back and numbness in my legs due to nerve damage. Started with 30mg, now only take 10mg. It works for me, virtually pain-free. Do have dry mouth and sometimes have bad dreams, but I can manage that as I can walk without pain and still go to work."

8 / 10
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  • TCA...
  • November 17, 2019

For Depression "This was super effective for both severe treatment-resistant depression, anxiety, chronic vestibular migraines, panic attacks, and even helped a bit with social anxiety and OCD. Never had such remarkable effects from any other drug before, even with SSRIs/SNRIs (which made depression worse) and MAOIs. I started feeling better the very first day, and within a few days, I had old emotions back that I hadn't experienced in years. Unfortunately, I developed a drug allergy to this drug, but it is not the drug's fault but my immune system. The drug still gets a 10/10, and I will be trying another TCA soon, hoping it works just as well! Also, don't worry about the anticholinergic effects of this medicine/other TCAs. The anticholinergic side effects of this medicine can actually be of benefit in treating your depression and should rather be called 'effects' than 'side-effects' and embraced and accepted as potentially positive."

10 / 10
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  • chi...
  • Taken for 1 to 2 years
  • June 26, 2014

For Pain "I'm being treated with nortriptyline for abdominal wall pain due to having irritable bowel syndrome (IBS) for almost 40 years now. I still have pain in other areas but this does the trick for the abdominal pain, which is like the pain you get in your side after you've been running for a long time. It wasn't just a stabbing pain, though, it came, it stayed, and wouldn't go away. I only take 10mg and my prescription says to increase as necessary, but I've been on it successfully for over a year now. I stopped it once with the OK of the doctor, but within three weeks, the pain returned, so I started back up on it. I do have the dry mouth and sometimes restless sleep, but I can handle that...I couldn't handle the abdominal pain...this worked!"

8 / 10
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  • Oll...
  • August 19, 2013

For Pain "I take Nortriptyline 30 mg at bedtime for facial nerve pain brought on by shingles, Post-Herpetic Neuralgia. The medication helps to stop itching, gnawing pain, and electrical firing. The one drawback for me is the constant obsession with food, mostly carbohydrates. I've gained weight and have negative sexual side effects, but hey, I'm not in pain. It would be nice if there was another medication that worked as well as this medication for the pain but didn't have the side effects."

9 / 10
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  • Vot...
  • Taken for 1 to 6 months
  • August 25, 2019

For Depression "I was hospitalized for depression recently after many hospitalizations. I have tried almost all of SSRIs, and the only one that slightly helped was Wellbutrin. It stopped working for me in the last year, along with lithium. I was prescribed nortriptyline in the hospital, starting at 10 mg up to 100 mg. Shortly after the 100 mg, I experienced a feeling of being on speed. The surge of rage took over me and caused so many panic attacks. After a visit to the ER, it was reduced to 85 mg. After a couple of days on 85 mg of nortriptyline, I felt like my old self again. In disbelief, my lack of motivation was gone, and I experienced “my old self”. So far, it has been a week, and I feel very good. I hope this lasts as I’ve been experiencing treatment-resistant depression for 4 years now. Let’s hope this tricyclic antidepressant is the answer for me."

8 / 10
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  • Anonymous
  • April 24, 2009

Nortriptyline for Migraine Prevention "I had taken almost everything for migraines and came up with a combination of Topamax and Elavil. I work in intensive care and started having memory problems. I also started sleeping almost constantly. I scheduled an appointment with the neurologist at my hospital and started on nortriptyline. This is the first time I've had total control. I'm not sleepy and I have more of my old self back. It feels good not to have any pain."

10 / 10
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180 Report
  • lur...
  • February 23, 2013

For Irritable Bowel Syndrome "I have had Irritable Bowel Syndrome for 30 years, and it has gradually gotten so bad that I told my doctor that I could no longer have a normal life, and I hated what Irritable Bowel Syndrome was doing to me. He prescribed 10mg of nortriptyline, and I highly doubted it would help. I was already on another antidepressant. However, it helped so much... it is a godsend! I can now enjoy life again. I can eat! I am not worrying about how I am going to get through the day with stomach pain. I can make plans to do things. I can enjoy my family and work again."

10 / 10
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