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Moxifloxacin and Tiredness: What Users Say

Brand names: Avelox, Avelox I.V.

Tiredness: mentioned by 15 users (7.1%)

Based on user experiences from 212 Moxifloxacin reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

dizziness 18.9%
nausea 15.6%
anxiety 9.9%
tiredness 7.1%
headaches 6.6%
lightheadedness 6.6%
fatigue 6.1%
increased heart rate 5.2%
loss of appetite 5.2%
insomnia 4.7%

Reviews for Moxifloxacin

Commonly mentioned side effects
  • Anonymous
  • August 22, 2012

Moxifloxacin for Bronchitis "This is very strong medication. I came from abroad with a bronchial infection and had to see my doctor. Cephalexin and Clarithromycin prescribed to me abroad by doctors apparently could not suppress the infection, and my doctor put me on Avelox on a 7-day course. I finished the course with great reluctance yesterday. It did relieve the symptoms to a great degree, but the side effects have been severe. I have severe loss of appetite, continue to be nauseous, lethargic, experience loss of energy, and became dizzy. I had extremely uncomfortable palpitations, tightness, and pain in the chest throughout the course and several sleepless nights. I have lost nearly 5 pounds over the seven days."

3 / 10
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52 Report
  • bmu...
  • June 11, 2013

Moxifloxacin for Pneumonia "I was surprised that the 1st night I noticed a huge difference in how I felt. I have not had any of the side effects that are listed except for being tired. I am on day 6 and I am still amazed at how it does work. The cost is the only thing I do not like about this medicine. But if I had to take it again, I would."

9 / 10
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36 Report
  • Mrs...
  • Taken for less than 1 month
  • December 15, 2017

Moxifloxacin for Bacterial Infection "I will ALWAYS remember back in 1998 when I was prescribed Avelox 400 mg. After taking one dose, this left me lethargic and with a feeling of being in a catatonic state of mind! I literally felt overpowered by this antibiotic. When I discussed it with my doctor, he educated me NOT to take any medications related to Avelox, such as Levaquin! Why? They're in the same family of drugs! (Quinolones) Do your research so you are well aware of what you're taking!"

1 / 10
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17 Report
  • Tak...
  • July 4, 2015

Moxifloxacin for Pneumonia "I am on a 14-day course of Avelox for pneumonia. Apparently, it was quite well spread over both lungs. The first course of antibiotics made no difference. Ended up in emergency, where they did a CT scan, and I was given 2 lots of antibiotics via a drip. Was sent home with Avelox, which has improved things greatly. The side effects are I am very tired, no appetite! This medication is well worth the side effects. A very frightening experience!"

9 / 10
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18 Report
  • Anonymous
  • September 20, 2009

Moxifloxacin for Sinusitis "I know everybody's body is different and reacts differently to medications, but after the second dose, I was tingly all over, had a headache, severe anxiety, muscle aches, weakness, tiredness, dry mouth, and impulsiveness. Just be careful!"

3 / 10
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24 Report

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  • Anonymous
  • March 17, 2011

Moxifloxacin for Sinusitis "I was put on Avelox for a horrible sinus infection and chest congestion. My doctor never mentioned any of the possible side effects. Within an hour of taking the first dose, I became very tired, weak, and I had heart palpitations, and I had overwhelming anxiety. I am now on day 5, and the side effects have only progressed. The joint pain and muscle cramping, heart fluttering, fatigue, muscle weakness, nausea, blurred vision, loss of appetite, and tremors are enough to scare anyone. It has helped my congestion and sinus infection, but there are other antibiotics that are just as good and so much safer."

4 / 10
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18 Report
  • Anonymous
  • October 2, 2011

Moxifloxacin for Bacterial Infection "The next day after taking it, I began to have twitching in my hands and fingers, dizzy, could not walk a straight line, and was extremely tired, sleeping 20 hours (I usually sleep 6 hours). After being taken off, after 3 days, most of my strength has returned, still a bit lightheaded. Apparently, these effects affect 2% who take the medicine."

1 / 10
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  • Anonymous
  • April 4, 2012

Moxifloxacin for Pneumonia "I am on my sixth day of Avelox 400 mg for pneumonia. I have noticed a big change in my breathing, and I do feel better. Still counting down to the last 4. Mostly because after I take it, I start feeling depressed, ill, tired, and still cannot eat or drink much. So I dehydrated to the point that I could not understand what people were saying. Nothing made any sense. That is better now, but still get confused, dizzy, lightheaded when I walk, depressed, and so on."

7 / 10
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20 Report
  • Anonymous
  • April 4, 2011

Moxifloxacin for Sinusitis "My brother took this and felt very anxious, my only side effect is feeling super tired and kind of out of it. It really helped my cough, and I think it is starting to help with my chronic sinus infection. I am allergic to Levaquin, so I was nervous taking it since it is in the same drug family. I did not have the same reactions that I had when I was taking Levaquin. I have had five sinus infections in the past six months, and the Z-pac has quit working... so overall things are getting better."

7 / 10
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14 Report
  • m h...
  • Taken for less than 1 month
  • November 14, 2022

Moxifloxacin for Intraabdominal Infection "After 4 failed antibiotic regimens (and 6 doctors), I finally discovered mycoplasma hominis infection, which had now been in my kidneys for 8 weeks. I am a 55-year-old male and have high energy, but the extreme lethargy and fatigue kept me in bed a crazy amount of time - could do almost nothing! It was helpful reading other reviews here as I have never been so tired in my life! But the drug worked (it is one of the very few that are successful on this germ) - I took probiotics and was fortunate not to have diarrhea. Just remind yourself the drug is doing its job and try to suffer through the side effects!"

9 / 10
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  • Anonymous
  • Taken for less than 1 month
  • January 19, 2018

For Sinusitis "I am on day 6 of a 7-day course of Avelox. My chest has cleared up, but my sinus pain continues. I have quite severe side effects, though... lowered heart rate, dry mouth, and cold hands and feet for about an hour post. Also, nausea on and off. Extreme tiredness, mental confusion, some mood changes, and irritability. These symptoms do get better, however, as the day goes on."

7 / 10
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3 Report
  • ata...
  • Taken for less than 1 month
  • February 14, 2019

For Sinusitis "My doctor prescribed me this medication because after a different round of antibiotics I still was not feeling better. I took 1 dose of this drug at 6 pm and within an hour my legs and arms were numb. I felt like I was having panic attacks with my heart racing, plus I was unable to sleep. It lasted for about 15 hours. During the morning after through about early afternoon, I was still feeling very anxious but completely exhausted from not sleeping, and I was in a complete fog. All I kept thinking to myself is when are these side effects going to end! I am not even thinking about taking the 2nd pill! Do not take this medication! The side effects are very dangerous!"

1 / 10
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3 Report
  • Par...
  • Taken for less than 1 month
  • October 24, 2015

For Bacterial Infection "Just completed a 10-day course. First two days, minor improvement in breathing, but then relapse. I feel just as bad, plus now I'm tired all the time. Don't know if it is from the medication or the fact I have asthma and I'm not getting 100% oxygen to my brain. This is my second round of antibiotics, the first was doxycycline for 5 days. I have been living with this for 9 1/2 weeks. My coughing is really bad and congested. I frequently cough up phlegm. Also have bad post-nasal drip."

3 / 10
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4 Report
  • Sas...
  • Taken for less than 1 month
  • July 25, 2021

Moxifloxacin for Bacterial Infection "I am on my 4th day of Avelox and going to try and stick it out despite the side effects. I was on another antibiotic for (Amoxicillin) diverticulitis last week, and it caused such bad diarrhea that I had to be switched to this. The 1st day I took it in the middle of the day. I had horrible nausea and dizziness, plus extremely fatigued. After that, I switched the time to after dinner before bed, and the side effects are easier to manage through the night. The only other problem is the extreme tiredness during the day. It seems to be clearing the diverticulitis, so I am going to finish the course."

6 / 10
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  • Boo...
  • Taken for less than 1 month
  • November 25, 2020

For Intraabdominal Infection "Goodness gracious! $230 for the antibiotics! I've been in extreme pain, gone to the hospital several times. My doctor prescribed me antibiotics, and it happened to be this! I'm breastfeeding and constantly feeling sick, and oh so tired, so badly, and the pain is still there?"

1 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.