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Moxifloxacin and Fatigue: What Users Say

Brand names: Avelox, Avelox I.V.

Fatigue: mentioned by 13 users (6.1%)

Based on user experiences from 212 Moxifloxacin reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

dizziness 18.9%
nausea 15.6%
anxiety 9.9%
tiredness 7.1%
headaches 6.6%
lightheadedness 6.6%
fatigue 6.1%
increased heart rate 5.2%
loss of appetite 5.2%
insomnia 4.7%

Reviews for Moxifloxacin

Commonly mentioned side effects
  • Min...
  • Taken for less than 1 month
  • February 20, 2020

For Bacterial Infection "I have mycoplasma genitalium. I’ve had it for nearly a year now. Was given other antibiotics before, but they were not effective, so now I’m on a ten-day course with moxifloxacin. I was ridiculously scared to take the tablets after reading into it so much and seeing the possible dangerous side effects, but decided I would do whatever it takes to get better. 4/10 days, I’ve had dizziness and fatigue, muscle ache, headaches that come and go, a little bit of tingling here and there in the arm, have also found myself getting very agitated and have been quite emotional. It’s not the easiest course to go through, but things seem to be clearing up."

5 / 10
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46 Report
  • Anonymous
  • August 22, 2012

Moxifloxacin for Bronchitis "This is very strong medication. I came from abroad with a bronchial infection and had to see my doctor. Cephalexin and Clarithromycin prescribed to me abroad by doctors apparently could not suppress the infection, and my doctor put me on Avelox on a 7-day course. I finished the course with great reluctance yesterday. It did relieve the symptoms to a great degree, but the side effects have been severe. I have severe loss of appetite, continue to be nauseous, lethargic, experience loss of energy, and became dizzy. I had extremely uncomfortable palpitations, tightness, and pain in the chest throughout the course and several sleepless nights. I have lost nearly 5 pounds over the seven days."

3 / 10
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52 Report
  • nur...
  • September 8, 2011

Moxifloxacin for Pneumonia "I am a FT RN working in an infectious disease unit. I am consistently exposed to respiratory viruses during the winter months; meningitis, encephalitis, and abscesses in the summer months; with a little variety thrown in here and there (asthma, pneumonia, Kawasaki, septic babies, etc.). I recently came down with a nasty RLL PNA and was prescribed this Avelox 400 mg, on day 14 of 20. Thus far, I have noticed tremendous improvement, but I am not 100% quite yet. Yes, the side effects/warnings can be scary, but the only thing I have noticed is fatigue and muscle/tenseness. Benefits always have to outweigh the risk, and I believe this medicine can keep many of us out of hospital beds and on the road to recovery quickly."

9 / 10
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44 Report
  • Anonymous
  • October 19, 2011

Moxifloxacin for Bacterial Infection "I can't wait until tomorrow. I took my last Avelox today, and unfortunately, it took me this long to figure out it was making me feel so sick. Nervous, shaky, nauseous, and my whole body is fatigued. I can't concentrate on my work and feel dizzy."

2 / 10
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43 Report
  • Kai...
  • Taken for less than 1 month
  • May 30, 2013

Moxifloxacin for Sinusitis "I took a 10-day dose 1 year ago for a sinus infection, and only remember feeling much better in a short time. Since I was already miserable, I don't remember having any adverse reactions. Recently, I got a 7-day dose for another sinus infection and an ear infection, and I felt good on days 3 and 4 with only mild nausea and dizziness. Taking it on a full stomach helped. I started to feel poor on day 5 and developed a terrible headache that lasted 2 days. By day 7, I developed severe fatigue, muscle, tendon, and joint pain. I agree with other reviews, in that this is a very effective medicine, but the side effects can be severe. I am glad to hear that these go away in a few days."

5 / 10
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32 Report

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  • Anonymous
  • December 20, 2011

Moxifloxacin for Sinusitis "On day 3 of 7 being treated for pneumonia, sinusitis, and ear infection. PROS: I can breathe again. I feel like the pressure in my chest is lifting. My ear pain is almost completely gone. CONS: Extreme fatigue, severe body pain (hands, wrists, ankles, and knees), insomnia."

3 / 10
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29 Report
  • Arr...
  • May 12, 2014

Moxifloxacin for Bacterial Infection "I get horrible side effects from literally every other antibiotic out there, except for Avelox. Of course, all medications affect people differently, but I have never felt any of the effects people list here, except for a little fatigue. This medication works very well."

10 / 10
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18 Report
  • Anonymous
  • March 17, 2011

Moxifloxacin for Sinusitis "I was put on Avelox for a horrible sinus infection and chest congestion. My doctor never mentioned any of the possible side effects. Within an hour of taking the first dose, I became very tired, weak, and I had heart palpitations, and I had overwhelming anxiety. I am now on day 5, and the side effects have only progressed. The joint pain and muscle cramping, heart fluttering, fatigue, muscle weakness, nausea, blurred vision, loss of appetite, and tremors are enough to scare anyone. It has helped my congestion and sinus infection, but there are other antibiotics that are just as good and so much safer."

4 / 10
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18 Report
  • m h...
  • Taken for less than 1 month
  • November 14, 2022

Moxifloxacin for Intraabdominal Infection "After 4 failed antibiotic regimens (and 6 doctors), I finally discovered mycoplasma hominis infection, which had now been in my kidneys for 8 weeks. I am a 55-year-old male and have high energy, but the extreme lethargy and fatigue kept me in bed a crazy amount of time - could do almost nothing! It was helpful reading other reviews here as I have never been so tired in my life! But the drug worked (it is one of the very few that are successful on this germ) - I took probiotics and was fortunate not to have diarrhea. Just remind yourself the drug is doing its job and try to suffer through the side effects!"

9 / 10
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3 Report
  • Pan...
  • Taken for less than 1 month
  • May 16, 2018

Moxifloxacin for Sinusitis "Awful side effects! I was fatigued, trembling, and experienced shortness of breath and tachycardia. I even started feeling knee pain after the second day of treatment. I couldn't sleep for three days and just had a mild improvement in my sinuses."

5 / 10
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8 Report
  • And...
  • Taken for less than 1 month
  • May 28, 2023

For Bacterial Infection "I’m on day 3. Feeling extremely anxious, multiple panic attacks, diarrhea, fatigue, lightheadedness, some back aches, fast heartbeat. I’ll continue with it as these symptoms seem to come and go alongside the anxiety. The problem is I have no way of contacting a doctor for the next few days, so I kind of just have to push through."

5 / 10
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  • Sas...
  • Taken for less than 1 month
  • July 25, 2021

Moxifloxacin for Bacterial Infection "I am on my 4th day of Avelox and going to try and stick it out despite the side effects. I was on another antibiotic for (Amoxicillin) diverticulitis last week, and it caused such bad diarrhea that I had to be switched to this. The 1st day I took it in the middle of the day. I had horrible nausea and dizziness, plus extremely fatigued. After that, I switched the time to after dinner before bed, and the side effects are easier to manage through the night. The only other problem is the extreme tiredness during the day. It seems to be clearing the diverticulitis, so I am going to finish the course."

6 / 10
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  • the...
  • March 27, 2015

Moxifloxacin for Sinusitis "Works great, but side effects are horrible. Sweating, dizziness, dry mouth, fatigue, next sinus infection. Give me something else, doc."

6 / 10
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12 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.