Methotrexate for Psoriasis User Reviews (Page 3)

• Anonymous
• June 15, 2008

"I tried a number of different treatments, but only methotrexate helps. I had it in my scalp, back, genital area, mostly body parts that were not exposed to sun and air, which I find interesting. My doctor said sun exposure would help, and it works for me. Still have a little on my scalp, but usually one application of Olux will clear it up."

• Raz...
• Taken for less than 1 month
• October 14, 2016

"I had a good experience with methotrexate. I've been fighting with psoriasis for the last 8 years. I'm 35. I tried so many things. One of my doctors gave me methotrexate just to try on me 4 years back. 2 tablets a week. For 3 weeks. For example, if I took one tablet in the morning and one in the evening on Monday. Then the same dose on next Monday. And the last one next Monday. So after this dose, my psoriasis disappears for 6 to 7 months. I repeat this dose once a year. But the best effective treatment for me was herbal treatment from China. I stayed there for 3 weeks. They gave me herbals to boil and drink the water with a proper diet. I did this for 4 months, and my psoriasis was gone for 12 months. I was not able to continue that diet and treatment."

• Red...
• Taken for 1 to 2 years
• November 29, 2017

"Have done 3 'rounds' of this, 4 weeks each, and have never been so exhausted, sick to my stomach, and out of it. It helped clear up the guttate psoriasis and inverse psoriasis, but didn't do much for the psoriatic arthritis."

• Cra...
• Taken for 10 years or more
• February 2, 2024

"Have been taking Methotrexate for plaque psoriasis (up to 75% skin coverage) for 46 years (I am 75 now). Dosage has been 25mg once weekly. Had two liver biopsies earlier in my treatment, both good. For the last 30 or so years, I have just relied on liver function blood tests - all good so far. I was lucky, I guess, that I never experienced gut issues or hair loss. I am mostly 100% clear. Infrequently, I find a small patch on the scalp area, but MTX has been a godsend for quality of life improvement."

• azu...
• June 6, 2013

"Just started a week ago. Was nervous regarding side effects but bit the nerves. Notice there is no flaking after one week. Although still itchy, hopefully that goes away. Just felt like I was exhausted faster but want to keep giving it a try. Tried everything else."

• eni...
• March 3, 2009

"I have been on methotrexate now for 6 months. It's great, as I was 85% covered with psoriasis and it improved almost instantly by 90%. Although there is one drawback, I get recurrent bouts of bacterial vaginosis, which is most uncomfortable, and have to then take a high dose of antibiotics (which make me feel very sick for a few days)."

• kul...
• Taken for 1 to 6 months
• December 30, 2015

"I've been taking this medicine for 9 weeks now. I'm taking 7.5 mg once a week but have seen NO difference whatsoever! All I seem to be getting is little boils everywhere, sickness, nausea, and weight gain! :("

• Anonymous
• Taken for 1 to 6 months
• May 17, 2017

"I have been extremely tired, nauseous, a general feeling of lack of interest in things I enjoy, moody, and overall not feeling good. The psoriasis has become less thick, but after six weeks, it's still there. I have an appointment Thursday and am going to discuss alternatives."

• Aus...
• February 12, 2016

"On methotrexate for 20 years, no issues with liver function. Otezla worked much better, but insurance refused to cover it, back on metho. Psoriasis since age 7, psoriatic arthritis since 40s. Now 54. Increased metho from 10 mg/week to 15 mg/week, pain and scaling more severe. New patches around my eyes, lids are swollen, painful, and itchy. Eyes constantly dry, red, painful, itchy - might have psoriasis and/or psoriatic arthritis in them, going back to rheumatologist and an ophthalmologist for help. OTC allergy eye drops, soothing drops, and nightly administration of Vaseline in/around eyes not alleviating condition. Very sore all over, sunny weather alleviates the patches and joint/tendon pain. Can't wait to sunbathe! No biologics, cancer scare."

• Jka...
• Taken for 6 months to 1 year
• May 28, 2019

"I have suffered from psoriasis for about 12 years but had a serious bout of arthritis 2 years before that, so psoriatic arthritis. Was able to stay away from chemicals for years, managed using supplements, but it carried on spreading. Finally referred to a dermatologist and was on cyclosporine for over a year, had to come off due to effect on gums and high BP, which was controlled with tablets. On methotrexate since October, no nausea, etc., but had lots of urine issues in the beginning, which I later realized was actually due to too much folic acid. Lowered the folic acid dose, and it was sorted. Recently realized that my joints and muscles have been hurting since I started methotrexate. Painful feet, legs, etc., affecting my everyday exercise routines, so will be speaking to a dermatologist about it in about two weeks."

• Cou...
• May 27, 2017

"I'm 18 and have had psoriasis now for almost 2 years. I started taking this for my psoriasis about a month ago and have already seen substantial differences! No itchiness, limited redness, and extreme scaling. Although the medication does take a bit longer to start working, I'm absolutely sure that it will continue to help relieve the psoriasis on my legs, arms, and stomach!"

• Bet...
• January 12, 2016

"I've had psoriasis for the past 10 years and was exhausted from trying creams and such. I searched for a treatment that would do more - and have been on methotrexate for about 7 weeks now. I haven't noticed any change in my skin - at least not for the better. I've been really itchy, and I really feel like my scalp has gotten worse. I have flakes constantly, and my head is covered in acne and red bumps now. My face is getting a bit of acne too. And, despite the fact that I eat very healthy and work out, I have put on about 2 pounds per week. :( So sad."

• Tri...
• Taken for 2 to 5 years
• March 21, 2019

"I've been on methotrexate for 3 ½ years for a mystery rash, 4 areas on my thighs, 4 on my back, and one in my heel. Dosage scaled up to 20 mg 1x per week and I recently reduced to 7.5 mg/week. Folic acid 1 mg/day. It did eliminate my rash, where no other drug, aside from prednisone, would. I developed tinnitus (ears ringing) 3 weeks ago and discontinued methotrexate. Ears are ringing constantly. I believe it is from methotrexate, I have otherwise excellent health and hearing. Wondering if anyone else has experienced ears ringing from methotrexate. I have not had any other side effects others have reported - hair thinning, liver impairment, etc."

• Adr...
• Taken for 1 to 6 months
• December 29, 2023

"After 3 weeks using this medicine, I’ve seen drastic changes in my skin. I could honestly say my skin is finally healing after being covered around 75% of my skin. I’ve tried Enbrel and Otezla, and I did not see results like methotrexate. So far, I have not had any symptoms to this medicine. Like many people, I was skeptical and scared to try this medicine based on the side effects, but I don’t regret giving this a try. The healing definitely outweighs the side effects, in my opinion."

• Sno...
• August 1, 2015

"I have suffered with psoriasis for 30 years and have tried every possible lotion, potion, shampoo, etc. that my dermatologist has recommended. I started taking 10 mg methotrexate once per week only 1 month ago. I have not noticed any reduction in scale patches, and I am still quite itchy. Is this normal?"

• Seb...
• March 30, 2017

"I have had psoriasis for 12 years. It affected my daily life. I have tried so many creams, ointments. Nothing worked. So last November, the doctor prescribed me Otezla, it hurt my back badly. I have to stop this. So methotrexate was given to me 5x2.5 mg per week in January, 1 mg folic acid per day except the day taking methotrexate. Once a month, blood work was given. I was on 7x2.5 mg last month. Now I am on 9x2.5 mg, I can feel it is almost clear, and I do feel joint pain and a weak immune system. I have such a bad flu right now and could go to the office tomorrow."

• Wan...
• June 29, 2011

"I have had severe psoriasis on my hands, elbows, and heels for the past 2 years. Came out of nowhere. Tried everything out there (steroids, antihistamines, light treatments (two periods of it). So now I'm on this medicine. It's only for the second week, but the only difference I see is getting a urinary tract infection. Hopefully, I will see improvement soon."

• Pic...
• April 30, 2016

"After 20 years of psoriasis and having had light treatment and creams, I was prescribed cyclosporin, which was fantastic. Almost clear within 2 weeks, but over a long period of time, it affected my kidneys. Been on methotrexate for 1 week, 12.5 mg per week, and no real change. Not as quick as cyclosporin, but I am hopeful it will clear soon."

• Mic...
• May 31, 2015

"68 year old male who has had psoriasis for 46 years with coverage up to 90% of my body. No one would initially Rx me methotrexate, so I flew to Trinidad from Canada to see a doctor there that would prescribe it. After the initial treatment, I was totally free for three years, then it came back. I was on every research program my cream passes could put me on: PUVA, Soralyn, vitamin A, coal tar, retinoic acid, that stuff that turns everything purple (can't recall the name). Finally, I had to see a head shrinker, as I was fairly emotionally messed up. He Rx'd me methotrexate 2.5x3 every 12 hours for 36 hours, said not to drink, and that I should get liver biopsies. I've had 10 invasive liver biopsies in 46 years, 10 years ago, I said no thanks, no more. I'm clear."

• kim...
• March 26, 2010

"I have had psoriatic arthritis since age 10. The deformities in my hands are very, very severe. I have taken methotrexate for about 6 weeks and don't notice a difference, except I have been feeling sick to my stomach, tired, and bowel movements are painful and a little blood is visible. Kinda scary-I see my rheumatologist in a few weeks. Psoriasis patches seem burning or itchier."

• nic...
• March 14, 2017

"I am 25 years old, and I have had psoriasis since the age of 20. The treatment that helped to completely eliminate the psoriasis was methotrexate and solarium. Now I have no psoriasis, and as a treatment (to prevent it from appearing again), I need to do solarium for 5 months of the year."

• Bev...
• September 1, 2020

"Was on methotrexate for over a year for psoriasis. First tablet form, then changed to injections. Was stopped due to pains in side 2 weeks in on injections. Have just started cyclosporine 100 mg twice a day to be increased to 150 mg after 4 weeks, and the difference in my hands' psoriasis is amazing after just one week on methotrexate."

• Mar...
• Taken for less than 1 month
• June 3, 2019

"I was just diagnosed with psoriasis about 2 months ago. I tried all kinds of creams and ointments, put my feet in Saran Wrap when I went to sleep. Nothing seems to work. It's on the bottom of my feet and my hands. My hands are scaly, dry, and cracked, and my hands hurt all the time. My feet are dry and cracked with scales all over them, mostly, it hurts my heels when I walk. The doctor put me on this medication and with folic acid too. I've been on it a week now, haven't seen any results yet, still in a lot of pain. Hope it works."

• chu...
• Taken for 1 to 2 years
• November 23, 2020

"I took methotrexate for about a year and a half before I took myself off it for about 2 years. I didn't experience much other than it had completely cleared my psoriasis. However, saying this, whenever I did take it, I just felt unwell. I cannot explain how it made me feel, but I can still vividly remember it. Due to my skin becoming increasingly worse, I have been forced to go back on this medication."

• sca...
• Taken for 1 to 6 months
• December 14, 2021

"I have had psoriasis since 2008. I am 67 years old and have had psoriasis on the bottom of my feet since 2008. Last summer, it showed up on the palms of my hands, between my fingers, and the tips of my fingers. Having been advised by my dermatologist to take methotrexate years ago, I finally gave in and started taking 15 mg once per week and 1 mg of folic acid 6 days per week. I started this regimen in October. My feet and hands are finally starting to clear. The first day after the meds, I feel wiped out. I wish I had started taking this medication a long time ago. This medication has given me my life back!"