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Tirosint and Heart Palpitations: What Users Say

Heart palpitations: mentioned by 7 users (5.0%)

Based on user experiences from 140 Tirosint reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

hair loss 12.9%
fatigue 9.3%
weight gain 9.3%
anxiety 8.6%
insomnia 8.6%
headaches 6.4%
chest pain 5.7%
swelling 5.7%
heart palpitations 5.0%
dizziness 4.3%

Reviews for Tirosint

Commonly mentioned side effects
  • Nat...
  • Taken for 10 years or more
  • March 14, 2019

For Underactive Thyroid "A word of caution about levothyroxine - not all levothyroxine drugs are equal. I recently experienced a nasty episode with generic levothyroxine because the manufacturer changed the formula (replaced lactose with mannitol) which made me very sick for months (dizziness, nausea, over tiredness, chest pain, and arrhythmia). It took a while to figure out since there was no communication of a 'change' from the manufacturer. The switch to 'Tirosint' was a lifesaver! Right away, the symptoms subsided. It is so important to check the excipients (fillers). Tirosint has glycerin, water, levothyroxine, that's it! As an NTI drug (narrow therapeutic index), I would never risk the generic again. I was too sick and spent too much money with docs who couldn't find anything wrong with me! After doing research, I asked for just ask for the brand - I am so glad as it solved all of my 'issues'!"

10 / 10
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  • And...
  • October 10, 2018

For Underactive Thyroid "I have Graves' disease and took RAI (radioactive iodine (I-131)) to treat the disease, which means now I have to top up my thyroid levels. I've previously taken Levoxyl, Synthroid, and lastly Armour. I always felt miserable with Levoxyl and Synthroid, which is why for the last three years I was taking Armour. Within the last year of taking Armour, I've had terrible inflammation, joint pain, anxiety, insomnia, hair loss, dry skin, weight gain, and the list goes on. It was coincidental that I forgot to take an Armour pill and realized how in one day all my symptoms went away. The next day I took my Armour and they all returned. It was so bad that I couldn't even bend my knees. I was miserable! I've been reading about Tirosint for the last few months, and my endo was more than accommodating to let me try it. WOW! What a difference! I'm not as hungry, losing weight, no anxiety, sleeping through the night, and overall just feeling great, as I've never had thyroid issues. However, I did have some heart palpitations last night. I'm going to get my lab work done today, as I feel the dosage may be too high."

10 / 10
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  • Pen...
  • Taken for 1 to 6 months
  • April 3, 2019

For Hashimoto's disease "After nature thyroid and Armour seemed to not be working, I was put on Tirosint by my endo. I felt great the first week or so, but since then I’ve had heart palpitations, fast heart rate, swollen legs and ankles, hair falling out, and in the short 2 months I’ve been on it, I put on 13 lbs. While all these symptoms were going on, my TSH was 0.20, which meant I was very hyperthyroid."

1 / 10
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Frequently asked questions

  • Mis...
  • August 29, 2020

For Hypothyroidism, After Thyroid Removal "I was on name brand Synthroid from 2008 until 2019, my doctor switched me to Tirosint thinking that I would have less heart palpitations and better absorption. I was on 200 mcg of Synthroid, TSH was 0.01, I am now on 112 mcg of Tirosint with a TSH of 0.1. I gained a significant amount of weight, so my endo doctor added 5 mcg of T3, I have not lost any of the weight. Since starting Tirosint, my weight has increased from 116 lbs to 130-131. I exercise and move a lot and do watch what I eat, although I do allow sweets in moderation as I always have. I have also noticed an increase in hair loss, a lot of hair loss, and very dry hair, thankfully, I have thick hair, but the dryness is awful. Long story short, I don't believe Tirosint is the right medication for me as I have gained so much weight and lost a large amount of hair, even with the added T3, which didn't help to change the weight issues. I will be requesting to go back to name brand Synthroid with the added T3 to see if this helps."

3 / 10
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  • Dtr...
  • August 17, 2016

For Hashimoto's disease "Love Tirosint. My hair is back and fingernails are not broken anymore. Feel great. Was on Armour for 6 years, got hair loss and lost beautiful nails. Previous meds gave me heart palpitations and I was not able to sleep. This med is the real deal, but it's too expensive."

10 / 10
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38 Report

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  • Dee...
  • September 6, 2015

For Hashimoto's disease "I was so excited to find this medication. I had previously been on Synthroid and its generic for over 20 years with no problems and suddenly became intolerant with debilitating side effects. We tried adding Cytomel, which caused terrible heart palpitations, and then tried Armour, also causing terrible heart palpitations and chest pain, both meds were reduced greatly with the same effect. I finally found Tirosint and did wonderfully on it for over 6 months. Then my stomach had severe issues. Through specialists and so many tests, treatments, and a whole lot of money, we finally stopped Tirosint on a whim. I'm all better stomach-wise, but out of options otherwise. Since even compounded T4 uses fillers, I have no more options."

2 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • June 7, 2017

For Hashimoto's disease "I was on Synthroid 50 mcg and generic levothyroxine 50 mcg. With both medications, I had palpitations, heat intolerance, and severe insomnia. Synthroid was worse than levothyroxine. My TSH numbers were fine, but I couldn't tolerate the insomnia. The positive thing was that I lost 30 pounds. I was switched to Tirosint 50 mcg and immediately could finally sleep. No more insomnia, no more palpitations, no more heat intolerance. I recently got my lab work back, and I have a normal TSH, but I've started getting hypothyroid-like symptoms I used to have when I was on no thyroid medication. So even though my TSH is normal and I can sleep, I am having weight gain, increased constipation, and hairline eczema. Alas, I will try another brand!"

9 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.