Skip to main content

Tirosint and Chest Pain: What Users Say

Chest pain: mentioned by 8 users (5.7%)

Based on user experiences from 140 Tirosint reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

hair loss 12.9%
fatigue 9.3%
weight gain 9.3%
anxiety 8.6%
insomnia 8.6%
headaches 6.4%
chest pain 5.7%
swelling 5.7%
heart palpitations 5.0%
dizziness 4.3%

Reviews for Tirosint

Commonly mentioned side effects
  • Nat...
  • Taken for 10 years or more
  • March 14, 2019

For Underactive Thyroid "A word of caution about levothyroxine - not all levothyroxine drugs are equal. I recently experienced a nasty episode with generic levothyroxine because the manufacturer changed the formula (replaced lactose with mannitol) which made me very sick for months (dizziness, nausea, over tiredness, chest pain, and arrhythmia). It took a while to figure out since there was no communication of a 'change' from the manufacturer. The switch to 'Tirosint' was a lifesaver! Right away, the symptoms subsided. It is so important to check the excipients (fillers). Tirosint has glycerin, water, levothyroxine, that's it! As an NTI drug (narrow therapeutic index), I would never risk the generic again. I was too sick and spent too much money with docs who couldn't find anything wrong with me! After doing research, I asked for just ask for the brand - I am so glad as it solved all of my 'issues'!"

10 / 10
Was this helpful?YesNo
269 Report
  • Jia...
  • Taken for 1 to 6 months
  • November 2, 2015

For Underactive Thyroid "Devastating side effects - I have developed severely crippling joint pain in both knees, debilitating nerve pain in feet after 12 weeks of taking this drug for underactive thyroid. Also experiencing muscle spasms, tremors, depression, suicidal thoughts, restlessness, some chest pains, and tingling all over the body. If I could have given it a lower rating, I would have."

1 / 10
Was this helpful?YesNo
121 Report
  • Sal...
  • Taken for 1 to 6 months
  • October 7, 2020

For Hashimoto's disease "I was prescribed Tirosint-SOL in May 2020 for Hashimoto's disease. The first month was fine with slight heart racing at night. Then on July 1, I had chest pains during the night. I stopped taking Tirosint and called my doctor. At first, I thought it was COVID-19, and I got tested - it was negative. I stopped taking all thyroid medicine. I had chest pains throughout July. Well, long story short, I had an emergency triple bypass operation on July 27. I am 65 years old and without any other health issues. I do NOT recommend this medication. The side effects can be awful. I do not want anyone to go through this experience."

1 / 10
Was this helpful?YesNo
82 Report

See also:

Frequently asked questions

  • sor...
  • Taken for 1 to 6 months
  • May 4, 2019

For Hypothyroidism, After Thyroid Removal "I loved it for the first month. Then, I developed agonizing headaches and chest pains. Had to go to the ER four times in pain. They could not do anything. Seven months later, I am still in pain and have to go to a gastro specialist to find out what is wrong in my stomach. It is really scary. I think it gave me some kind of ulcers in my stomach."

1 / 10
Was this helpful?YesNo
41 Report
  • Hop...
  • Taken for less than 1 month
  • June 3, 2016

For Hashimoto's disease "I hope that the FDA is reviewing and testing Tirosint. Thought I was going to die after only taking a low dose of Tirosint for a few days. Chest pains, extreme disorientation, very sick, could not stop crying. The hospital did not know what to do. My pharmacist suggested drinking lots of water to get it out of me, which I did. Nightmare experience!!!"

1 / 10
Was this helpful?YesNo
56 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
  • Dee...
  • September 6, 2015

For Hashimoto's disease "I was so excited to find this medication. I had previously been on Synthroid and its generic for over 20 years with no problems and suddenly became intolerant with debilitating side effects. We tried adding Cytomel, which caused terrible heart palpitations, and then tried Armour, also causing terrible heart palpitations and chest pain, both meds were reduced greatly with the same effect. I finally found Tirosint and did wonderfully on it for over 6 months. Then my stomach had severe issues. Through specialists and so many tests, treatments, and a whole lot of money, we finally stopped Tirosint on a whim. I'm all better stomach-wise, but out of options otherwise. Since even compounded T4 uses fillers, I have no more options."

2 / 10
Was this helpful?YesNo
43 Report
  • Anonymous
  • Taken for 1 to 6 months
  • September 8, 2021

For Hashimoto's disease "Horrible medication. As a 65-year-old with a recent diagnosis of Hashimoto's disease, I was on this drug for 2 months. The second month, things got worse. Chest pains, not sleeping, terrible muscle aches. Well, I ended up in the emergency room with chest pains, which led to a triple bypass operation! This drug should be off the market!"

1 / 10
Was this helpful?YesNo
15 Report
  • phi...
  • December 1, 2015

For Hashimoto's disease "Absolutely terrible experience on Tirosint - landed in ER with chest pains, dizziness, extremely disoriented."

1 / 10
Was this helpful?YesNo
46 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.