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Lansoprazole and Upset Stomach: What Users Say

Brand names: Prevacid, Prevacid 24HR, Prevacid SoluTab, Prevacid OTC

Upset stomach: mentioned by 7 users (4.9%)

Based on user experiences from 143 Lansoprazole reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

headaches 8.4%
nausea 7.7%
diarrhea 6.3%
heart palpitations 6.3%
upset stomach 4.9%
anxiety 4.2%
cramps 4.2%
dizziness 4.2%
stomach pain 4.2%
burning 3.5%

Reviews for Lansoprazole

Commonly mentioned side effects
  • Luc...
  • Taken for less than 1 month
  • May 23, 2018

For GERD "I was suffering from reflux when my doctor prescribed lansoprazole. I had a bad allergic reaction to it. Besides the horrible skin rash, one of my kidneys started to fail, I was extremely dehydrated, and my stomach wasn't working properly. Lots of in and out of the hospital. After that, I can't ever again have any PPIs medicine. It was a horrible experience, and I thought it was important to share."

2 / 10
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  • mar...
  • Taken for 2 to 5 years
  • July 21, 2017

For GERD "I have done tons of research... Prevacid or Dexilant etc. are meant to be taken for about 2 months. Many people have been on it for years! Acid reflux can be caused by too little acid. Maybe the medication is making it worse. I am now feeling side effects (nausea and stomach cramping off and on for last year) or perhaps Apple cider vinegar does neutralize the reflux? If I forgot one pill, I would have heartburn by midday. I had the regular ACV, but they said it has to be organic with mother of the apple? A lot of people can be helped with organic apple cider vinegar... After a few days, with no medication, I have no heartburn. Just one tablespoon of ACV with one teaspoon of honey in warm water, morning and at supper, try it! :-)"

5 / 10
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  • Jay...
  • Taken for 1 to 6 months
  • September 14, 2019

Lansoprazole for GERD "Started taking Prevacid about a month ago. It started off great. It was working wonders. Then my GERD started to act up at night. I was initially on 30 mg, and I would take that just in the morning, now I'm taking it in the morning and in the evening. Still all good. However, recently I've been getting severe stomach aches and nausea. I felt extremely weak and had nonstop diarrhea as well. I drank some Gatorade, which actually fixed it. I wonder if there's some sort of electrolyte imbalance with taking Prevacid. Either way, I'm probably going to wean off of it. The constant nausea isn't worth it."

5 / 10
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62 Report

Frequently asked questions

  • Jil...
  • Taken for 1 to 6 months
  • April 9, 2020

For GERD "I've used lansoprazole for 9 weeks. It worked fantastically, but now I think it's lowered stomach acid too much. I have told my doctor I will stop taking it as of tomorrow, as I took one today and will only take it if/when symptoms recur. It has given me a stomach ache and loose morning movements, plus I've lost a bit of weight that I can't afford to."

7 / 10
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  • leo...
  • Taken for 1 to 6 months
  • December 15, 2022

Lansoprazole for Duodenal Ulcer "Started taking Prevacid about a month ago. Started off okay, working well enough, but at night it seemed to not be strong enough to last the 24 hours. I was initially on 30 mg, and I would take that just in the morning and night, now I'm taking it in the morning. Now I've been getting severe stomach aches, headaches, and nausea. Felt extremely weak, and the anxiety-induced body pain feels like I've had pots of coffee, with irritation so severe, I just can't take it anymore."

2 / 10
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12 Report

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  • 14a...
  • August 2, 2011

For GERD "It works wonders for the heartburn, but I can't handle the side effects. I have awful diarrhea, vomiting, weight gain, headaches, nausea, and stomach aches. It's not the normal side effects, but I haven't had any heartburn. I'm probably in that >1% that has bad side effects."

4 / 10
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  • Ano...
  • Taken for 1 to 6 months
  • October 25, 2019

For Gastritis/Duodenitis "I am currently taking lansoprazole to treat gastritis for a second time. The first time, I took the medication for a month, which seemed to clear my symptoms. After another flare-up, I am back on lansoprazole. So far, so good - the medication has been very effective. I have been suffering from constant bloating and stomach discomfort, and lansoprazole has massively reduced both."

7 / 10
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17 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.