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Lansoprazole and Nausea: What Users Say

Brand names: Prevacid, Prevacid 24HR, Prevacid SoluTab, Prevacid OTC

Nausea: mentioned by 11 users (7.7%)

Based on user experiences from 143 Lansoprazole reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

headaches 8.4%
nausea 7.7%
diarrhea 6.3%
heart palpitations 6.3%
upset stomach 4.9%
anxiety 4.2%
cramps 4.2%
dizziness 4.2%
stomach pain 4.2%
burning 3.5%

Reviews for Lansoprazole

Commonly mentioned side effects
  • JPa...
  • August 21, 2020

For GERD "I began having GERD during this quarantine. My son, who is an MD, helped me work my way through the OTC remedies, getting little relief, until I landed on lansoprazole. I had a normal first five days, no GERD, then I became VERY ill. I had violent diarrhea for 18 days, nausea, cramping, loss of 7 pounds, headache... even went to the ER because I was feeling so badly. I took a list of my medications and no one mentioned the complications. No one considered the lansoprazole pill. I was told to eat a soft diet: rice, broth, potatoes, etc. I continued to take the pill a few more days, my weight falling, much gurgling, lack of interest in food or life in general, sweeping nausea, and running for the bathroom as many as 15-20 times a day and literally all night. I continued taking the pill until I ran across an article that listed my symptoms, though rare, as caused by the drug. Beware, I had a particularly bad reaction."

2 / 10
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  • mar...
  • Taken for 2 to 5 years
  • July 21, 2017

For GERD "I have done tons of research... Prevacid or Dexilant etc. are meant to be taken for about 2 months. Many people have been on it for years! Acid reflux can be caused by too little acid. Maybe the medication is making it worse. I am now feeling side effects (nausea and stomach cramping off and on for last year) or perhaps Apple cider vinegar does neutralize the reflux? If I forgot one pill, I would have heartburn by midday. I had the regular ACV, but they said it has to be organic with mother of the apple? A lot of people can be helped with organic apple cider vinegar... After a few days, with no medication, I have no heartburn. Just one tablespoon of ACV with one teaspoon of honey in warm water, morning and at supper, try it! :-)"

5 / 10
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125 Report
  • Jay...
  • Taken for 1 to 6 months
  • September 14, 2019

Lansoprazole for GERD "Started taking Prevacid about a month ago. It started off great. It was working wonders. Then my GERD started to act up at night. I was initially on 30 mg, and I would take that just in the morning, now I'm taking it in the morning and in the evening. Still all good. However, recently I've been getting severe stomach aches and nausea. I felt extremely weak and had nonstop diarrhea as well. I drank some Gatorade, which actually fixed it. I wonder if there's some sort of electrolyte imbalance with taking Prevacid. Either way, I'm probably going to wean off of it. The constant nausea isn't worth it."

5 / 10
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62 Report

Frequently asked questions

  • Joh...
  • Taken for 5 to 10 years
  • November 30, 2019

For GERD "It all started with heart palpitations, numbness on one side (I sleep on my side), bloody mucus in the nose, headaches, nausea, vertigo, and so on. My fam doc ordered ECG, stress test, etc. After 6-8 months of weekly/biweekly visits, embarrassed to go back to him since he started to think it was all in my head, I went to a random walk-in clinic where a young doctor called it out: silent GERD. Lansoprazole has worked after a few days, and I got reaffirmed that it was not all in my head, there was an underlying problem to my symptoms. After a few months, I stopped taking it, and that's when the heartburn started, so I went back on it. Lansoprazole may almost completely stop acid production or not work at all, so you really have to watch your dosing. At one point, I needed one 30mg in the morning and one in the evening. With it, I am able to eat whatever I want without having to worry about the aftermath. I'm talking hot peppers, sriracha, tomato juice, chocolate milk, etc. Good luck!"

9 / 10
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  • leo...
  • Taken for 1 to 6 months
  • December 15, 2022

Lansoprazole for Duodenal Ulcer "Started taking Prevacid about a month ago. Started off okay, working well enough, but at night it seemed to not be strong enough to last the 24 hours. I was initially on 30 mg, and I would take that just in the morning and night, now I'm taking it in the morning. Now I've been getting severe stomach aches, headaches, and nausea. Felt extremely weak, and the anxiety-induced body pain feels like I've had pots of coffee, with irritation so severe, I just can't take it anymore."

2 / 10
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12 Report

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  • Mma...
  • Taken for 1 to 6 months
  • December 22, 2020

For GERD "I was on omeprazole, and it didn't agree with me. I have never been so ill since I started this. It gave me constipation, I ended up getting taken to the hospital due to nausea, breathlessness, and constipation. Never again."

1 / 10
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  • Kil...
  • Taken for 6 months to 1 year
  • March 5, 2021

Lansoprazole for NSAID-Induced Gastric Ulcer "I started Prevacid because I needed something to coat my stomach while I took NSAIDs for back pain, costochondritis, and a slipped rib after I had my daughter (I’m small, and she was born big and took a toll on my body - had her when I was 40). It worked for taming the heartburn and indigestion but caused HORRIBLE constipation. I weaned off it, and constipation disappeared, and I had normal bowel movements almost immediately. But the acid rebound was AWFUL, AWFUL, AWFUL. I have been taking Pepcid and Tums as needed, but they are very short-term solutions. I also have had some weird brain fog/lightheadedness, nausea, headaches, fatigue. I wouldn’t recommend this. It wasn’t worth it in my opinion."

3 / 10
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  • 14a...
  • August 2, 2011

For GERD "It works wonders for the heartburn, but I can't handle the side effects. I have awful diarrhea, vomiting, weight gain, headaches, nausea, and stomach aches. It's not the normal side effects, but I haven't had any heartburn. I'm probably in that >1% that has bad side effects."

4 / 10
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  • rog...
  • February 22, 2022

Lansoprazole for GERD "I took the 2nd dose of Prevacid. It caused the sudden onset of extreme nausea and vomiting 2.5 hours after taking it. Maybe I should have taken it on a full stomach. All I know is that it made me horrendously ill, necessitating a visit to a local ER for hydration and Zofran."

1 / 10
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  • mys...
  • Taken for 1 to 6 months
  • May 12, 2022

For GERD "Well, there are pros and cons. The good: 1. Very effective for stopping the reflux 2. Fine for short-term use 3. No problem with the evening dose 4. Short-term use, few side effects 5. I'm less allergic to it than omeprazole Cons (for me, your mileage may vary): 1. Stomach pain kicked in late and doesn't go away 2. Extreme sudden fatigue with mild exertion 3. Morning nausea, worse if I stop the tablets, though 4. Sweating 5. Awful dry mouth, can't drive any distance without stopping to drink. We all have different experiences with these sorts of drugs. While there are very unpleasant side effects, there are great benefits. Acid reflux is worse than taking the tablets, there is no doubt about that for me. Some of us just don't react well to PPIs, I'm at peace with it. It's not the tablet's fault."

7 / 10
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  • Lem...
  • Taken for 2 to 5 years
  • October 3, 2021

For NSAID-Induced Gastric Ulcer "Absolutely shocking drug. Been on it for 3 years due to long-term use of ibuprofen for back spasms. Kept having bouts of diarrhea, then bad constipation, felt nauseous all the time, fatigued like I could just drop to sleep on the spot. Over the last few months, it has been building up in my system to severe constipation where I was so bloated I couldn't even let gas out, that nauseous and vomiting that I lost weight and that fatigued it was becoming difficult to remember who I was. 5 visits to A&E with a fully dilated pupil that would not shrink and no Dr. there told me it could be a side effect of lanzop. My Mum and I have ended up working out this tablet has caused everything and was probably causing the same thing to my late Grandad as he was put on this cheaper version from one that was working for him. Diabolical. I am now alert, eyes wide open, feeling like I want to eat, eating full plates of food, and bowels are back to how they used to be! Avoid this drug at all costs!"

3 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.