User Reviews for Dupilumab to treat Atopic Dermatitis
Also known as: Dupixent
Dupilumab has an average rating of 6.6 out of 10 from a total of 60 ratings for the treatment of Atopic Dermatitis. 55% of reviewers reported a positive effect, while 28% reported a negative effect.
Dupixent (dupilumab): “I started Dupixent in Feb for dermatitis. After 8 weeks I noticed a significant improvement. My body had been about 80% covered in red patches and all of it cleared. After 1 month passed I started experiencing terrible side effects. Including conjunctivitis, blepharitis and cracked skin on eyelids. I saw an eye doctor 3 times and was put on steroid eye drops. Later I saw an ophthalmologist to ensure my eyes weren’t being damaged by the steroids I was using. Luckily no significant damage was done, but side effects persisted. At the end of the 6th month I decided to stop. The side effects were outweighing the benefits. After being drug free for 2 months, my eczema hasn’t flared up at all. I am still suffering from the eye problems but I am hoping time will heal. My advice is, if you start feeling better don’t be afraid to stop the needle and start again at a later date if needed. You may have been experiencing a flare and once under control can be managed using other creams and less harmful options.”
Dupixent (dupilumab): “I had debilitating hives for over three years to the point I was no longer leaving my house because I was in so much pain and discomfort all the time. I saw every specialist my dr could think of trying to figure out what the underlying cause was but never did figure it out. My dermatologist suggested we try Dupixent and within a week I was almost 80 percent clear and now 3 years later I’m 100 percent clear. It has been a literal lifesaver for me.”
Dupixent (dupilumab): “I started this Dupixent in May 2019. Took a while to kick in, maybe August I noticed improvement. Fast forward to now, Oct 2019, I have been having horrible side effects for 3 weeks. I even had an MRI because I thought my circulation wasn't working properly. I have tachycardia, chest pain, shortness of breath, and pins and needles. I want this out of my system. I thought this would be a lifesaving medication. It is not now.”
Dupixent (dupilumab): “I have been taking the medication for a year now, and what can I say, but WOW at first I didn't know how to feel but to know it only took two weeks for my skin to clean up. I am super happy of this medication and whomever thought of this. And I was only out of pocket 0.00!!!!”
Dupixent (dupilumab): “Took the loading dose 600 mg and eyes got red, itchy and puffy. Advised my dermatologist and he gave me a Rx for and eyedrop called Bepahamide. This is a combination of steroid (prennisilone) and antibiotic in one eye drops. Both eyes twice a day for 10 days. Eyes got a little better. Took second dose (300 mg). Eyes got worse. Went back to dermatologist and he gave a second course of the same eye drop with no improvement. Went to My ophthalmologist. He did a complete eye exam. Ophthalmologist had to look up Dupixent when I told him it was one of the side effects of this medication. He suggested antihistamine otc eye drop called zantidor. Been using zantidor and still my eyes have not cleared. Saw noticeable improvement in my skin after first 2 doses but unfortunately stopped using dupixent due to severe eye irritation. Now what? My eyes aren't getting better and the dermatologist has gone back to topical corticosteroid can someone please tell me what to do about my eyes?”
Dupixent (dupilumab): “37, male, Asian, suffered from Atopic Dermatitis for 20 yrs. I took Dupixent over 6 months, and having trouble now. I felt my Atopic problem went away for first 2 months ( I took 3 shots for the 1st month, and 2 shots from 2nd months). As noticed side effect, my eyes got dry and itchy which is still bearable. What I think as a problem for now is the red skin syndrome. This started around the eyes and now spread under the neck- now to shoulder. The red spots make white skin flake and hurts when the flake removed, and looks wrinkled. Now I'm considering to stop this medication and return to other treatments.”
Dupixent (dupilumab): “I received the loading dose of dupixent on 11/15/19. On 11/19/19 I developed intense (full body) pruritus, urticaria, and a "drug reaction" appearing rash. This is on top of my flared atopic dermatitis state. The itching and rash appearance is unbearable. I have been absolutely miserable with this discomfort. I am now on a 2 week prednisone taper, a 5th high potency topical steroid cream, routine prednisone and both an H1 and H2 blockers in attempts to compact this reaction. I am eagerly awaiting the dupixent medication to rid to system, however all the information that I have read indicates that the half life is unknown. I pray that no other adverse reactions present themselves in the meantime.”
Frequently asked questions
- How fast does Dupixent work?
- What is Dupixent used for and how does it work?
- How do you inject Dupixent?
- How do you use Dupixent?
Dupixent (dupilumab): “I started Dupixent in September 2019, it is now February 2020. I am 24 and have had severe atopic dermatitis my entire life. For the first 3 or 4 injections this medication was a miracle, I was normal, no more shower routines, bed routines, or creams. However, I began to develop large red blemishes around my neck and on my face. At first they did not itch, then a week later it was like my condition came back but twice as bad. The weather also got very dry and cold at this time so at first I wasn’t sure if it was the weather or the medicine. Now, 2 months later, my bad condition still persists and I have developed seborrheic dermatitis, which I’ve never had before. I feel the medication is to blame for this and I will be discontinuing Dupixent. Also the hotline is terrible and trying to actually talk to somebody about this drug and its effects is almost impossible. This forum is the best source of info I’ve found.”
Dupixent (dupilumab): “I never thought my skin would be clear enough to wear shorts, I have never in my life wore shorts...... until now. I am so glad that agreed to use dupixent. My asthma and eczema have not had any flare ups since a couple days after the 1st 2 injections. I am only not excited about the injections, but the needle is so small, it's livible.”
Dupixent (dupilumab): “I had chronic dermatitis and asthma all my life (I am 70) possibly due to Ichthyosis. I didn't believe the photos I was shown of Dupixent results. I've been on a shot every 2 weeks for about 6 months now and my eczema has cleared up so that I can actually sleep without scratching myself to pieces first. I can't tell you what a difference it has made to my life. No irritation, little flaking. I am trying to work out if I can come off my asthma medication now (Advair and Flovent). I can't see or feel any side affects.”
Dupixent (dupilumab): “I have always had eczema but since 2015, it has made my life unbearable. I changed my diet which helped with relief from occasional asthma attacks, itchy eyes and congestion but eczema got worse. I started Dupixent in March 2019 and it worked like magic. My skin was perfect and I felt great. However, in the beginning of August, I got Conjunctivitis and Blepharitis. The Ophthalmologist said I might have to stop the injection and it breaks my heart. I hope it was a one-time issue and I can continue the medication. And I hope the researchers who worked on this drug can make it better so that it doesn't have the side effects it has now. I don't want to go back on steroids.”
Dupixent (dupilumab): “Definitely wasn’t what I was hoping for have seen skin about 25-30% clearer extremely dry face bout same as b4 I still get rashes on my back off and on neck is still inflamed regularly been on for about 8 months now Have a flare up right before shot and it never seems to take effect for at least 2 days after and I will clear up slightly for a few days then I will go back to whole body rash itching hasn’t been relieved much at all it’s an ok alternative to other drugs and worth the attempt but it doesn’t work great for me wish everyone luck”
Dupixent (dupilumab): “I was on Dupixent for one for year and the beginning I had itchy red very dry eyes than later developed extreme joint pain in my knees and ankles but I cleared up my skin look great for year until I realized my aches and pains were due to the Dupixent also weight gain I got off of it and now my rashes are starting to come back but just not worth the side effects that Dupixent gave me not willing to go back on Dupixent”
Dupixent (dupilumab): “My baby brother died in February and I went from being a pretty healthy person to having pus ooze from head, feet, toes, arms, knees and ankles encrusted, bleeding and my right hand so cracked up I could barely use it. Staph infection, kidney stones etc etc. Ready to end my journey because I had always had a quality of life. Turned 60 in Nov. Now I have been on dupixent for a month..my second shot and my body is clearing up. No cracks in my hands, I'm a little scared BUT I'm willing to see what will happen to my body on the drug. I can't imagine living with this for years.,.I just can't imagine it. A co-worker (who has the same) and I discussed whether the idea of getting some ailment from taking the drug to living with the eczema. Hands down..give me the drug. Life is to be lived...my family needs to see me back. I am getting there I hope. Prayers for every ones journey!!”
Dupixent (dupilumab): “Have been on oral steroids for 44 years daily for severe atopic eczema, asthma and sinus atopic allergies. This medicine has finally given me a chance to start cutting back on the steroids. I am very optimistic about my condition, and hope to be steroid free in a few months. The only side effect I had was red eyes the first 2 months. That went away and I have had no other side effects. I hope this will be more affordable in the future for those that don't have good health coverage.”
Dupixent (dupilumab): “I was born with what they thought was eczema. At age 35 they determined I have allergic atopic dermatitis. I am now 45 and have been on Dupixent for 7 months. It has changed my life for the better. I have a wonderful Dermatologist and she really works with me, listens, and cares. She has helped me to remove as many allergic triggers as I can and I believe that also helps keep the flare ups away. The best thing to come out of taking the Dupixent is the absence of the constant itchiness and irritation. I have had one flare up since being on the medication and it was super mild. I have been so fortunate that I have not experienced the side effects that I keep reading about. I did have excessive watering of my eyes and when I had a glass of wine my face was briefly flushed but I will take that over the everyday suffering. My family is still in shock when they see me.”
Dupixent (dupilumab): “I started Dupixent August 2017 to replace the cyclosporine and it helped cosmetically with my skin but does very little to stop the itch. My AD is severe and after reading the trials it was only about as effective as cyclosporine but w/o the side effects. I scratch throughout the day - not 24/7 but enough to suffer from sleep deprivation and the social stigma of scratching and having skin come off due to how vigorous I scratch. Sheets changed weekly with blood spots from the bleeding.”
Dupixent (dupilumab): “I’ve only been taking Dupixent for about a month and already have seen quite an improvement to my SEVERE eczema. I’m also a brittle asthmatic and have noticed I’m using asthma inhaler 1/3 LESS than I was before so that was a GREAT surprise and bonus! My skin is not completely clear or nearly smooth yet but I know not to even expect to see full results for 3-4 months so given that, I give this medication an 8. I would never give it a 10 given the ridiculous cost but the ease of pharmacy delivery and administration of the drug in pre filled, syringes with retractable needles are great convenience so that bumps the ratings up a bit. I am VERY HAPPY with my results from Dupixent so far!”
Dupixent (dupilumab): “I was on Dupixent for a year and one month. I've been on Prednisone 10 mg for 55 years. It cleared up my Asthma, Eczema and Nasal Polyps. I was now down to 5 mg and was going to keep tapering further. However , I was losing my hair and starting to get close to balding. It's confusing, because it effects people differently. I think it will benefit a lot of people. Unfortunately I have made the decision to stop using it. I don't want to go bald. I understand that it does cause this in some people Good luck to all.”
Dupixent (dupilumab): “Started dupixent in Oct 2018 right away less itching , by the next month skin is beautiful said wow this is great. Then in Jan 2019 I developed cold sores blepharitis, weight gain , body aches , got flu shot thought that it made me even worse after that because I couldn’t even bend down after that shot then I had to hold my head to get out of the bed my neck was hurting stopped the shot in April 29 2019”
Dupixent (dupilumab): “I've now been on Dupixent for 6 months. Starting last March, I was not only getting my usual eczema, but I was also getting welts and contact dermatitis for unknown reasons. I was literally up all night itching, and showers were excruciating. I decided to go on Dupixent because topical treatments were no longer working for me. Within the first month on Dupixent, my body was basically clear and my itch had drastically decreased. However, within about 3 months, I did begin to notice some unique looking rashes on my face and around my eyes. Fast forward to 6 months later, and my eyes are indeed watery and itchy like others have mentioned, but it's not totally unbearable yet. I got in contact with my dermatologist, and he said that there is a theory that Dupixent basically uncovers an allergy to ingredients that are commonly present in cosmetics and lotions. I'm not quite ready to give up on Dupixent yet, as it's greatly improved my quality of life in other ways.”
Dupixent (dupilumab): “I was diagnosed about 15 years ago with prurigo nodularis. My current dermatologist labels it as atopic dermatitis. I started using Dupixent in April, after a month I saw significant results. Enough to stop using Prednisone. Though the injections are painful and leave me with an onsite reaction for almost a week with each injection, I endured it because my itching had stopped. 7 months later, I'm having spots appear and I am getting itchy again. I will speak to my my next month about stopping treatment. I also have joint pain all over my body, which may or may not be caused by dupixent.”
Dupixent (dupilumab): “My skin has improved 100% since this drug. I had horrible itching and topical treatment only made the creepy crawly intense itching worse. I would scratch till there was blood and my skin oozed but still I would itch. I can sleep! It's so worth the side effects! After a year all of the dry itchy eye & swollen lids have gone!”
Dupixent (dupilumab): “Started on Duprixent six weeks ago, Skin cleared up, itching was reduced 85% big relief, but within 2 weeks after my first dose, my eyes started to bother me. Itching, swelling, redness, Dry eye, Conjunctivitis. Way too many adverse side effects Med does good, but has alarming bad side effects to the eyes..... Went to Dr. told me to stop taking shots...........”
Dupixent (dupilumab): “I have been on Dupixent for 4 weeks. My skin began to clear up after two weeks and now is nearly completely cleared up. Itching is another problem. It is now starting to stop. So, so far I'm pleased. My only worry is how long do I have to be on Dupixent. It has been hard to get an answer--my doctor said one year but in another place I read that I'll always be on it.”
This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare professionals.
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