Trulicity and Upset Stomach: What Users Say (Page 3)

• Don...
• Taken for 6 months to 1 year
• April 21, 2018

For Type 2 Diabetes "I started on Trulicity 1.5 with horrible side effects for 3 months. I have been on 0.75 now for 6 months and still have stomach cramps and some off days, have lost nearly 20 lbs and am not overweight. My thyroid readings have been out of range since taking this drug, cannot get a response from Eli-Lilly or Trulicity regarding this change. My doctor thinks my thyroid med isn't working, funny it's worked for 7 years with no issues until now! Not sure what I will do yet. It would be nice if the company cared to respond like they said they would!"

• Reb...
• Taken for less than 1 month
• June 12, 2017

For Type 2 Diabetes "I am a pre-diabetic and overweight and was prescribed this to help lose some weight. In my opinion, this drug is horrible. Took my 1st and ONLY injection Thursday, come Friday night I could barely move. My stomach and sides were so sore. Saturday I slept all day, had a low-grade fever, severe stomach pains, nausea, loss of appetite, headache. Sunday I went to the ER because I got worse and couldn't take the stomach pain. The doctor said it was a reaction from this drug. He gave me fluids due to dehydration from explosive diarrhea and morphine for severe pain. Today I left work early because not only am I having horrible diarrhea, I am vomiting like crazy. Low-grade fever again. I feel so sick. I would not recommend this medication at all. Of course, you're going to drop weight from vomiting and diarrhea."

• Anonymous
• Taken for 1 to 6 months
• June 14, 2017

For Type 2 Diabetes "I have been on Trulicity for 10 weeks. The first month I lost 13 lb, but nothing more. I still get a headache the day after the shot and a little upset stomach. Still helps my cravings a lot. Just wondering if aggravation is a sign. Just started doing this about 2 weeks ago. My sugar has dropped low to where I start to shake and feel sick to my stomach. I feel like it has helped."

• MK ...
• Taken for less than 1 month
• July 14, 2019

For Type 2 Diabetes "Instant head spins, nausea, chest pounding, stomach cramping. Felt very sick, felt like stomach stopped working, with bloating and cramping. Also constipated for 4 days. Has been 7 days now, body starting to function again. Would not recommend. Warning, be VERY careful."

• Dom...
• February 22, 2017

For Type 2 Diabetes "Four weeks now on this medication, first 3 weeks on 1.5, then they reduced it to .75. Still no different, and I am NOT taking another one! The vomiting and diarrhea is crippling me, having to take two days a week off sick. I can't do this. I've lost just under a stone in weight, and I'm not that big to start with! The constant stomach cramps, not wanting to be far from the loo, are taking their toll! It hasn't helped my sugars at all, if anything, it's worse! Good luck."

• San...
• Taken for less than 1 month
• August 3, 2018

For Type 2 Diabetes "Within an hour of taking my first injection, I had severe nausea, stomach cramps, and diarrhea. Because this is a once-a-week dose, the med has stayed in my system. It’s been six days, and I’m just now starting to feel better. I’ve been confined to my home because I can’t be far from a bathroom. Fortunately, I have Tricare, who, even though made me change from Byetta to this, they’re allowing me to go back on Byetta since I gave Trulicity a try; they’ll go back to paying for my Byetta."

• Eda...
• Taken for less than 1 month
• April 19, 2019

For Type 2 Diabetes "A little nausea, curbed appetite, and seems to be getting rid of foggy head. Stools different but no massive diarrhea. So far, I am pleased with Trulicity. I take omeprazole, which helps with upset stomach."

• Mic...
• June 16, 2016

For Type 2 Diabetes "Been on Trulicity for 4 months. Seem to tolerate it very well, infrequent bouts of diarrhea, some stomach upset, but no episodes of throwing up. Does not seem to handle carbs well, but minor carbaceous meals will do better. I supplement with about 40 units of Lantus insulin to help the A1c. I will also do some occasional use of Humalog if sugar is too high before the next meal or arising in the morning. I have had about 7 pounds of weight loss."

• Gch...
• Taken for less than 1 month
• December 20, 2017

For Type 2 Diabetes "Please don't take the side effects lightly if you experience them. I took two doses (two weeks) and experienced some stomach issues the first week. The second week started as the same kind of stomach pain, but it was more than just the nausea. The medication was causing problems with my pancreas, and I ended up being hospitalized."

• MLV...
• Taken for 1 to 6 months
• June 5, 2019

For Type 2 Diabetes "After 3 months on Trulicity for type 2 diabetes, I've gained 10 lb. My stomach hurts/cramps. The worst is the fatigue, I've not been physical in 2 months, which would account for the weight gain. My daily insulin use is the same or a bit higher since I'm not able to leave my porch, the yard work and lake activities are non-existent using this drug."

• Ber...
• Taken for less than 1 month
• June 20, 2019

For Type 2 Diabetes "I started using Trulicity on 6/11/19; immediately I saw impressive results with my glucose numbers. I also experienced a rapid decrease in appetite. I track my calories in very closely, and I could barely get 700 calories a day for the first week. By day 5, I was vomiting with terrible stomach cramps in the early morning (5 a.m.). However, my glucose numbers remained 99-140 the entire first week. On 6/18, I took my second dose of Trulicity. The next day, I could barely function; my stomach was in so much pain. I have been nauseated just about every day since my initial intake. I haven't had a bowel movement in 13 days. And my stomach felt like a soda bottle shaken up and someone was slowly twisting off the cap. Today, I called my doctor with my side effects, and they want me off of Trulicity and back on slow-acting Lantus."

• Reb...
• November 15, 2016

For Type 2 Diabetes "I began this medicine on Thursday. I was fine until Saturday. Upset stomach, only getting worse after that. I have been going to the bathroom off and on all night and all day Sunday. Horrible cramping and gas. I have lost a total of 4 pounds from this in the last few days. I am very weak. My blood sugars have come down, but I have only eaten bananas and applesauce, and some diet ice cream seems to soothe my stomach temporarily. I am beyond miserable. I do not recommend this."

• Flo...
• Taken for less than 1 month
• February 26, 2018

For Type 2 Diabetes "My side effects outweighed the benefits of this medicine. Stomach cramps, chills and sweats, muscle pain in legs and arms, vomiting, and nausea. My numbers did drop 25 points on the first day. But the side effects were every day and debilitating for me. I will never take this medicine again."

• Cle...
• August 13, 2018

For Type 2 Diabetes "I've been taking Trulicity for several months. It's easy to inject. I was recently checked by my MD, and my A1C used to be a 10, now it is a 7, and hopefully next time I visit with my MD, it will be normal. Fried foods and sweets upset my stomach, so I don't eat them."

• Tru...
• Taken for 1 to 6 months
• June 4, 2017

For Type 2 Diabetes "I am on my 6th week with Trulicity .75 and Janumet 50/1000. My numbers have vastly improved. I had been on the Janumet alone for a while, but that made me have some terrible stomach issues. I had asked the doctor if I could discontinue the Janumet, but because my A1C was 12, she said not yet. The last 2 weeks, though, and especially this last week, the stomach issues have returned and seem to have worsened. I will discuss this with my doctor but was wondering if anyone else has had this or a similar experience."

• Do ...
• Taken for less than 1 month
• July 27, 2017

For Type 2 Diabetes "I was on Trulicity .75 for two weeks and was just upped to 1.5. My first injection went fine until I woke up the next morning with severe body aches in all my joints and having stomach aches and diarrhea. That lasted for about a week. I took the second .75 shot and had no body aches but still get the occasional stomach ache and still having diarrhea, have to stay close to a bathroom. I lost some weight even though it's only been two weeks, but maybe just because I'm on the toilet so much seems more goes out than in. My sugars didn't go down as much as I wanted but are definitely better. So in a few days I start 1.5, I hope this will do the trick."

• She...
• Taken for less than 1 month
• August 10, 2019

For Type 2 Diabetes "I take four Metformin and Trulicity, and every two weeks or so my stomach cramps like I have a virus, and then I throw up. TMI, but this looks like clear saliva mucus that comes up. Then sweat, and I have headaches throughout the night. I backed off Metformin to two to see how it goes."

• cdh...
• April 10, 2018

For Type 2 Diabetes "I take Metformin, have since 2008. Just last November, my doctor put me on 0.75 dosage because my A1C was 7.5. I was nauseated a few times, but it passed quickly. In February, my A1C had only dropped to 7.2, so she put me on 1.50 dosage. I have had horrible indigestion, stomach cramps, back pain, and just feel downright horrible with chest pains every time I eat, no matter what it is. I asked her to put me back on the lower dosage, so wish me luck. It did help me lose a little weight, even on the lower dose."

• Wen...
• November 2, 2017

For Type 2 Diabetes "This is week 2 on 1.5 Trulicity. I was diagnosed 3 months ago and started with a 12 A1C and a 285 blood sugar. I started on Metformin 1,000 x 2 per day and have really suffered the last 3 months with severe stomach issues. I have not had a normal bowel movement in 3 months. I have recently added Trulicity to the Metformin, and my A1C is now down to 7.2 and blood sugar down to 138 - almost to my target of 6.5/130. All of that in just 3 months, so for me, a lifesaver. I am still having the stomach issues, but honestly, not sure which medicine it is from, but I am willing to work through it to get me to a healthy place. I did notice the fattier the food I eat, the worse the cramping and bathroom issues."

• car...
• October 18, 2016

For Type 2 Diabetes "Started Trulicity one month ago. Daily blood levels are very positive. Side effects have been bothersome. Very tired the second and third day after the shot. Cannot overeat or stomach discomfort. Woozy when I first stand up. When I was taken off all meds, I felt great, but my numbers were high (over 200) in the morning. I am going to try the med until I get my A1C reading in December."

• Gle...
• Taken for 1 to 6 months
• April 1, 2018

For Type 2 Diabetes "Was on Trulicity for about a month, started getting bad stomach cramps, then a week after that, I started throwing up uncontrollably. I went to the ER and was admitted, had to have emergency gallbladder removal surgery. I haven't taken it since and have started walking and eating right, and so far, my sugar levels have been perfect. Doctor said my gallbladder was twice the size it should have been."

• min...
• Taken for less than 1 month
• March 15, 2018

For Type 2 Diabetes "My diabetes doctor decided Trulicity would be better because the Metformin just stopped working for me. I was put on it March 13th, 2018. My stomach was weird that night, the next day everything was okay, but by the 14th, that evening I threw up all my food. My stomach hurt, and the acid reflux from vomiting has my chest burning if I sneeze or cough. I will not be doing another dose of this stuff, although my numbers are low, it's not worth feeling ill."

• Son...
• April 6, 2018

For Type 2 Diabetes "I was diagnosed with Type 2 diabetes on 9/16. My A1C has been 6.5 - 7.0 during this time, blood sugar level between 100-120. Then the week of March 19th, 2018, I started experiencing frequent urination, dry mouth, and blurry vision. My sugar levels started being in the 300's-400's out of the blue. The doctor put me on Trulicity on April 1st, the side effects are horrible. Nausea, stomach cramps, I am experiencing them all. I have been on Trulicity for four days, and the lowest blood sugar level I've had is 216, and this was a morning fasting reading. I'm still in the 300's when I eat. Don't know if I am going to take my second dose on Monday. Not sure if I can take any more of these side effects and still have high blood sugar levels. Any advice?"

• But...
• Taken for 1 to 6 months
• April 15, 2021

For Type 2 Diabetes "This stuff was like poison for me. Nausea all the time. At week four, severe diarrhea for five days, followed by four days of awful stomach cramps to the point it almost made me make a trip to the E.R. now severely constipated. Energy level is non-existent. Had to call in to work twice in one week. Called my Dr. same old rubbish, body needs time to adjust. I stopped taking it myself because it was so bad for me!"

• 75...
• Taken for less than 1 month
• September 17, 2022

For Type 2 Diabetes "Wanted to get off Jardiance because of constant yeast infection and peeing. After two doses of Trulicity, I was so sick. Nausea was mild and went away, but diarrhea started. Second dose diarrhea became worse. One night I farted and had sulfur burps for 3 hours, I had stomach ache and no appetite. Of course, most people would lose weight living like this. But not me-not a pound. Then skin on my forefingers started to peel in chunks. That’s when I called the doctor and said I am going back on Jardiance. I waited 3 weeks until this drug got out of my system and blood sugars started to creep up. Only then did I restart Jardiance, so yes it will lower your A1C, but you feel like you are dying. Now I am stuck with over $200 of meds I can’t use."