Skip to main content

Trulicity and Burping: What Users Say (Page 2)

Reviews for Trulicity

Commonly mentioned side effects
  • Dlr...
  • Taken for 1 to 6 months
  • August 15, 2017

For Type 2 Diabetes "Took first shot in doctor's office 2 weeks ago, 75 mg, and started feeling a little unwell that night. Next day, extreme nausea, belching, just sick. Finally subsided night before second shot. Took second shot, helps with bringing numbers down, though. Side effects of fullness - you have to hydrate and eat smaller meals. Hope this helps someone. It does get better. Hope. Took third shot, experienced bad nausea and vomiting."

6 / 10
Was this helpful?YesNo
23 Report
  • Cha...
  • Taken for less than 1 month
  • December 1, 2018

For Type 2 Diabetes "Trulicity is the worst. I started on Saturday after Thanksgiving. On Monday at 4 pm, I started feeling bad. Got home from work, diarrhea set in, very nauseous, belching rotten eggs, the smell was horrible, pain on the left side, and I was very cold. I went to bed, got up the next morning, very, very sick. Went to work, coworkers saw me and said, 'Are you OK?' I had to leave early, missed work the next day. Rapid heartbeat by Thursday, a week later still not eating, very dizzy. Will never take again - nightmare. Quality of life sucks."

1 / 10
Was this helpful?YesNo
20 Report
  • Mic...
  • Taken for 1 to 6 months
  • June 24, 2016

For Type 2 Diabetes "Week 6 update... The first 5 shots (5 weeks), lowest dose of 0.75. I had the usual nausea for a day or two after each shot and loss of appetite... no big deal, as it felt good to NOT be hungry and craving the carbs! Week 6 was this past Sunday. No nausea, but started with the sulfur burps and diarrhea Thursday night. Might not be connected, seeing it is week 6 and NOT week 1 or 2? I am down around 11 - 12 pounds since starting 6 weeks ago. Levels have been running NO higher than 126... UNHEARD of for me :) Also take Metformin XR x2 pills daily. I am soooo anxious to get my A1c level checked in a couple of months :)"

10 / 10
Was this helpful?YesNo
26 Report

Frequently asked questions

  • Jh2...
  • Taken for less than 1 month
  • October 27, 2015

For Type 2 Diabetes "I received a sample from my Dr. to try before filling the script. Day I took the injection, I was fine. Day two had mild diarrhea. Day three, severe diarrhea & can't eat. I have literally had 5 crackers & a piece of toast in three days. Vomiting, horrible belching & abdominal pain & still more diarrhea. I am fighting to stay hydrated. I have an upset stomach with Metformin, so I should have known that this would cause problems. I'm convinced that the reason you lose weight with this is because you can't eat at all! I won't be taking a dose this week."

1 / 10
Was this helpful?YesNo
29 Report
  • Mic...
  • Taken for less than 1 month
  • July 22, 2019

For Type 2 Diabetes "I started taking Trulicity Thursday after a lot of apprehension due to reading not only bad but very worrying reviews on it. Well, I’m into my fourth day now and can very happily report it’s been fine apart from very slight nausea, which I can live with. I have had terrible trapped wind and burps at nighttime, which has kept me awake, but this is the first night I’m not suffering. My appetite has gone right down, and my sugar levels, although not completely down, are better than they were. To be honest, the very slight effects I have suffered have been nothing compared to the tiredness, sickness, and the feeling that comes with high sugar levels. For me personally, I can only give a positive review as so far, so good and have no real negatives to report. All I can suggest for anyone going onto this medication, it is worth giving a go. It may not suit everyone, but until you try it, you won’t know."

8 / 10
Was this helpful?YesNo
20 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
  • All...
  • Taken for less than 1 month
  • July 11, 2019

For Type 2 Diabetes "This drug is great for type 2 diabetics who exercise and eat right daily. I'm currently on my second dose and have lost 20 lbs in 3 weeks. I drank some tequila the third day after my injection and felt terrible. I experienced bad abdominal cramps, tons of belching, and diarrhea, so that's why I gave it an 8.0 because while you're on this medication, you'll have to do right. I don't eat chips, I eat trail mix and mostly high-grain bread, fish, and vegetables, and I consume 70 plus oz of water a day, so that's why this medication works for me. If you plan on eating whatever and drinking soda, juice, and alcohol, I do not recommend this medication. I have heard horror stories for those like this who took this medication. But if not, get it immediately and feel great."

8 / 10
Was this helpful?YesNo
21 Report
  • Dia...
  • Taken for less than 1 month
  • December 15, 2016

For Type 2 Diabetes "Took the first dose of Trulicity 1.5 Friday 12/09/2016. Saturday was fine. Blood sugar was okay. Taking with 75 units of Lantus in the AM and PM. Sugars are much better (97 this morning). Side effects are real for me though. But they are side effects I have been getting occasionally for the past year, before I started on Trulicity. The major issue for me is stomach cramps, gas (both ends). Sulfur burps are really really bad. Tons of gas. I vomited once and felt much better after doing so. Since I was experiencing these side effects randomly over the past year, I wonder if it's the Lantus - with Trulicity magnifying it. Pure speculation at this point. Dr. for another dose tomorrow. I will take it and see what the next week brings."

6 / 10
Was this helpful?YesNo
23 Report

More FAQ

  • miz...
  • Taken for 1 to 2 years
  • June 7, 2019

For Type 2 Diabetes "I have been on Trulicity for about 13 months. At first, I experienced nausea and loss of appetite. I lost 13 pounds within about the first 6 weeks! I took nausea medicine to help me get through the nausea symptoms. But it did help my A1C drop from 9.3 to 6.6. After several months, my symptoms subsided and I seemed to be on an even keel. My appetite returned and I gained weight back. All of a sudden, for the last 5 weeks, I have been sick as a dog! The nausea has returned, I have indigestion and belching like never before, and stomach pain. I am miserable. I am constipated, I am fatigued, and my kidney specialist tells me the Trulicity is causing my problems. I took my last injection 2 days ago, and the rest of it is going in the trash!!! No more for me."

5 / 10
Was this helpful?YesNo
17 Report
  • Sic...
  • Taken for 6 months to 1 year
  • August 21, 2018

For Type 2 Diabetes "Been on this drug for a little over a year. The side effects are awful! Constipation, headaches, sour burps/upset stomach, terrible heartburn, excruciating body aches, mostly in my legs and lower back. I can't manage to sleep more than an hour at a time. Most nights, I can only manage about 4 hours of total sleep because of the pain. My A1C increased and is only getting worse. My thyroid medication stopped working, and my hair is falling out at an alarming rate. I found this forum and realized that so much of my pain and issues could be caused by Trulicity. I never took another dose. It has been a little over a month. I feel so much better, no more pain or stomach issues, and my fasting levels are in the normal range (around 100) for the first time in a year. I don't get another A1C check till next month, but I am confident it will be better. I will never take this drug again!"

1 / 10
Was this helpful?YesNo
21 Report
  • Sar...
  • Taken for less than 1 month
  • July 15, 2019

For Type 2 Diabetes "The first day I injected Trulicity, I was fine. I felt a little nauseous the next day, but that night I could not sleep at all because I had the worst stomach pain and burps. I was running to the bathroom literally every half hour, and I cannot even keep water down. I am so dehydrated now. I regret taking it, as I am now exhausted from not being able to sleep. This medication is not worth it."

1 / 10
Was this helpful?YesNo
18 Report
  • All...
  • Taken for 1 to 6 months
  • February 1, 2020

For Type 2 Diabetes "Started Trulicity June 2019. For the first 12 weeks, it was great. A1C was down, lost about 8 lbs. Then the diarrhea, bloating, gas, and belching started. I would take it on Monday, and I was sick Wednesday and Thursday. Couldn't do anything. Tracked and limited the food I was eating, but I was still getting sick. My doctor did not know what the problem was. Finally, after a scope to make sure there was not a problem with my digestive system, I went off the Trulicity in December and am now back on Metformin. The sickness subsided. Even though I've been off Trulicity for about 2 months, I still have bouts of diarrhea, bloating, gas, and belching. I'm not sure if the Metformin is reacting with the Trulicity that's still in my system."

1 / 10
Was this helpful?YesNo
15 Report
  • Kor...
  • December 18, 2018

For Type 2 Diabetes "I have been on Trulicity for 3 weeks, and it has really helped me so much. I have finally started feeling better! I was starving all the time! It has helped with that. I am burping a lot, but to get relief, it is worth it to me."

9 / 10
Was this helpful?YesNo
17 Report
  • Haz...
  • Taken for 1 to 2 years
  • December 13, 2016

For Type 2 Diabetes "I've been on Trulicity for about a year. Started with .75, but now up to the 1.5 dose weekly. I find that my side effects actually come and go. I will go weeks without the sulfur burps, but then out of nowhere, they will show up again (like now). It's done a great job lowering my A1C, but be careful not to overeat, or your body will be unhappy. Unable to find the sulfur burp trigger, but still looking. For me, the benefits outweigh the negatives."

8 / 10
Was this helpful?YesNo
20 Report
  • Rig...
  • April 9, 2017

For Type 2 Diabetes "On week five of Trulicity. The first night I was beyond exhausted, went to bed at 7 pm, slept all night. Week 1 had every symptom and was so sick: vomiting, diarrhea, and this deep gut burping that smelled horrible. Week 2 was better, but week 3-5 are hit and miss. I have lost about ten pounds, mainly due to little to no appetite. I take my shot on Tuesday, and I vomit every Saturday. I miss about 1 day of work a week due to feeling horrible and dizzy. This drug is horrible, but my sugar with other meds is down to 7 from 9.8 in 3 months. The burping is the worst, it's like rotten eggs... so gross."

3 / 10
Was this helpful?YesNo
22 Report
  • Whi...
  • Taken for less than 1 month
  • April 10, 2018

For Type 2 Diabetes "Terrible experience. Shortly after taking on a Sunday, I was extremely fatigued. Lost all appetite the rest of the day and Monday. Constant hiccups and burping, acid reflux was so bad by Tuesday night it woke me up coughing it up. Appetite started to reappear by Wednesday, so had a smaller normal meal in the evening. Early hours of the morning, projectile vomiting and diarrhea. After reading reviews here and seeing that thyroid cancer is a risk, contacted GP. Advised to discontinue. Felt unwell and like a zombie all week. It's very worrying that there are no long-term studies of this medication in humans. It causes cancer in mice and rats. Because it hasn't been tested, it's not known if it will cause cancer in humans. So we're all guinea pigs."

1 / 10
Was this helpful?YesNo
17 Report
  • maw...
  • May 23, 2015

For Type 2 Diabetes "Been on for 3 weeks, take shot on Mon. Side effects started on day 3. 2nd week, day 4, this week, day 5. Upset stomach, vomiting, extreme nausea! Nothing helps! Horrible belching and gas! Cannot function on those days. Blood sugars are great! The jury is still out. Do these effects go away after a while?"

5 / 10
Was this helpful?YesNo
21 Report
  • Lyn...
  • November 23, 2016

For Type 2 Diabetes "I gave my first shot of Trulicity .75 last Wednesday evening. By Friday, I was absolutely sick to my stomach, accompanied by nausea. Finally took nausea medication, which helped. But later threw up. I have had severe diarrhea any time I eat something. Burping all day, and Sunday I could barely get out of bed, my energy was not there, and my body ached. Unfortunately, my 2 kids don't understand, so up and out of the house I went to buy a Gatorade, and I actually felt better after drinking a little. I'm afraid to take my dose tomorrow because I'm not sure I can deal with another week of these side effects... But they said to keep with it and your body will adjust... any advice if this is true?"

6 / 10
Was this helpful?YesNo
19 Report
  • Sha...
  • Taken for 1 to 6 months
  • October 30, 2019

For Type 2 Diabetes "Starting the second month of using Trulicity. Came on here to see what others have experienced as far as side effects. While I did experience sulfur burps and gas the first month, not nearly as bad as others describe. I've had gastric reflux for about 10 years before this drug, and it seems to be made worse, but I will give it more time since I am seeing normal blood sugars. I also use Humalog, Basaglar, Metformin, and Januvia. Thank God for health insurance."

8 / 10
Was this helpful?YesNo
15 Report
  • Jus...
  • Taken for 6 months to 1 year
  • March 7, 2016

For Type 2 Diabetes "Started Trulicity about 8 months ago at .75 mg... In the beginning, very queasy & complete loss of appetite, which was a great thing. Also belching & heartburn/sour stomach. I noticed after about 3 months the effects wore off, so my doctor put me on 1.5 mg 1x per week plus the .75 mg 1x per week. None of the side effects returned... My appetite is back, no queasiness, weight loss stopped, as well as no more sour stomach or belching. Wonder if anyone else has experienced the effects of the medicine wearing off as well. Not sure why I am still on it at this point! Also taking 1000 mg Metformin 2x daily & Invokana."

3 / 10
Was this helpful?YesNo
18 Report
  • Saf...
  • Taken for 1 to 6 months
  • October 16, 2018

For Type 2 Diabetes "My husband started taking this medicine back in July 2018. It made him really sick, he can’t eat, is complaining of stomach pain, back pain, burping a lot, complaining about not being able to swallow. He even said water burned to swallow. He kept taking it until September, and then he got really sick and has stopped taking it. He still suffers side effects today, still complaining of stomach pain and back pain."

2 / 10
Was this helpful?YesNo
14 Report
  • Jue...
  • Taken for less than 1 month
  • July 8, 2019

For Type 2 Diabetes "I took Trulicity for 2 weeks. I felt so nauseated that I had to call off work. The first 2 days I was fine, then I began to feel sick at my stomach, and I was gassy and belching all the time. I had to stop after the 2nd injection. This is not for me..."

1 / 10
Was this helpful?YesNo
14 Report
  • chu...
  • March 21, 2017

For Type 2 Diabetes "I started taking T 2 days ago, after being on Lyxumia for over 2 years. My HbA1c just keeps going up and up, have lost 10 kg over 2 years on injection and with 2000 mg of Metformin SR. Well, 2 days and I feel not too bad, have chronic runs, but I also get that since my gallbladder was removed. The sulfur burps are really rank! Will stick it out and see how it goes. My BG readings are down a little bit, so hope it continues. By the way, I am from the UK."

9 / 10
Was this helpful?YesNo
17 Report
  • Gra...
  • Taken for 1 to 2 years
  • December 30, 2021

For Type 2 Diabetes "After Metformin was no longer keeping my numbers down, my doctor suggested we add a new medication. He gave me a sack full of free samples of Trulicity. He said it was wonderful and should get me back in line. I started out on the lower doses, then eventually went to the 1.5 dosage until my numbers started creeping up again. That was about the same time that the 3.0 and 4.0 dosages had first been approved. I was put on the 3.0 dose. It brought my numbers back down, but the side effects were magnified and became intolerable. I ended up with heartburn so bad I started having to take daily heartburn medication. Then I started having severe episodes of what I initially thought was food poisoning. I had sulfur burps with severe vomiting and diarrhea so bad I had to wear adult diapers during those episodes. It turned out to be medicine-induced gastroparesis and pancreatitis. The once weekly shot was convenient but not worth the horrific pain and suffering it caused."

1 / 10
Was this helpful?YesNo
9 Report
  • Kit...
  • Taken for less than 1 month
  • January 27, 2022

For Type 2 Diabetes "I've been on this medication for only a week, and yesterday I woke up with sulfur burps and nausea so bad that I couldn't function half the day. Then today I felt great half the day, I finally ate at 2:30 a peanut butter sandwich. Within an hour, I started getting a headache that turned into a migraine, sulfur burps returned, and nausea so bad I feel like I can puke up my whole stomach if I had any food in it. I'm feeling absolutely horrible."

4 / 10
Was this helpful?YesNo
8 Report
  • Ste...
  • Taken for 1 to 6 months
  • July 11, 2018

For Type 2 Diabetes "I am now on Trulicity for three and a half weeks. I have experienced severe bloating, belching, and flatulence. Also, I have experienced sour stomach and acid reflux. The severe belching and flatulence is enough to keep me awake at night. I've tried Gas-X, does not help, and Rolaids. Has anybody experienced these side effects? On the positive side, my blood sugar has come down the last 75 points to be in the 120 to 130 range, which I have not been able to achieve with Tresiba alone. What I was really wondering, because of the positive effects of lowered blood sugar, will these symptoms subside eventually?"

8 / 10
Was this helpful?YesNo
13 Report

See also:

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.