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User Reviews for Dienogest / estradiol

Also known as: Natazia

Dienogest / estradiol has an average rating of 6.5 out of 10 from a total of 69 ratings on Drugs.com. 49% of reviewers reported a positive effect, while 30% reported a negative effect.

Condition Avg. Rating Reviews Compare
Birth Control  
6.3
53 reviews 340 medications
Menorrhagia  
7.0
16 reviews 2 medications
Summary of Dienogest / estradiol reviews 6.5 69 reviews

Reviews may be edited to correct grammar/spelling, or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published.

Reviews for Dienogest / estradiol

greys1879 May 1, 2020

Natazia (dienogest / estradiol) for Menorrhagia: “Absolutely INCREDIBLE pill. Natazia feels like I'm not even taking anything. No side effects at all other than really dry skin- no big deal. Without BC, I have nightmare periods that are horribly painful and insanely heavy that have been ruining my life & causing anemia. I was out of options as no other BC pill (I tried Loestrin, sprintec, Apri, & Ortho Tri Cyclen) was helping my symptoms and just caused a bunch of intolerable side effects and CONSTANT breakthrough bleeding with even worse cramps. This pill solved all my PMS symptoms and period issues and has given me a balanced mood and light pain free period that arrives exactly on time. I can't even comprehend how amazing I feel. This pill is changing my life. It seems too good to be true so I really hope it continues to work this well! If you don't tolerate other BC, definitely try this!”

10 / 10
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LB · Taken for 5 to 10 years June 4, 2019

Natazia (dienogest / estradiol) for Birth Control: “I’ve been on this birth control for 6 years and am very happy. I had very painful periods that would cause me to vomit from pain before. Now I have absolutely no period on this pill and love it. I skip the placebo pills and haven’t had a period in years. I do not want to have children so I’m not concerned with any infertility issues. I tried other pills that gave me mood swings, breakouts, and weight gain. This pill actually makes me feel normal -when I’m not on the pill I feel like my appetite is crazy. This pill helps regulate my appetite, helped clear my skin, and I have no periods at all for years. I’m very happy about all of these effects and I will continue to only use Natazia.”

10 / 10
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Sara · Taken for 5 to 10 years August 16, 2021

Natazia (dienogest / estradiol) for Birth Control: “The pill does what it’s supposed to do, but after a few years of taking this pill I started having very severe migraines with symptoms indistinguishable from ischemic stroke. I do not recommend taking this or any hormonal birth control pill long-term. Upon stopping this pill it took my body about a year to get back to normal hormonally, but the migraines stopped AS SOON AS I stopped taking the pill.”

5 / 10
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itzzkelsiee · Taken for 6 months to 1 year December 7, 2019

Natazia (dienogest / estradiol) for Birth Control: “I’ve tried at least 5 different types of birth control & none of them worked, I would gain lots of weight, they made me feel tired & sad. Natazia is a miracle!! I have PCOS & was bleeding for months straight. 9 months straight to be exact. I was tired of it & was finally recommended Natazia. After 6 months on it, my period is finally down to 3 days a month!! My cramps have seem to gotten worse but it’s better than bleeding constantly. Insurance gave me a hard time but after fighting, it’s free & I don’t have to pay $300 a month. I wouldn’t recommend any other birth control other than this one, with no symptoms & little bleeding, I couldn’t be happier!”

9 / 10
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College Athlete November 8, 2018

Natazia (dienogest / estradiol) for Birth Control: “I began Natazia at 14. I'm 21 so I've been on it 7 years. I have severe endometriosis, which is why I began the pill to treat it and preserve fertility. I've had laproscopy. Natazia made my periods very light and short or often, disappear. Pre-BC I had 12 day periods that were incredibly painful and heavy. Now I rarely bleed more than a day or two, even if I take the placebo. HOWEVER, I believe Natazia has caused incredibly severe and chronic issues for me. Appetite disorders, milia around eyes, severe anxiety, crippling depression, insomnia, exhaustion/tiredness, constant bloating, 10 lbs weight gain, nausea, headaches, nonexistent libido, dull hair, and uneven skin. I am very healthy otherwise as I am a college athlete and eat a plant-based diet. I really am considering stopping BC altogether this is truly unbearable. I'd rather bleed for 12 days than feel this way.”

3 / 10
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ohiogirl2 · Taken for 6 months to 1 year January 29, 2013

Natazia (dienogest / estradiol) for Menorrhagia: “I have been on this pill for 11 months. One thing with me for this pill is that I have to be very careful to take the pill when I'm supposed to. If it's a few hours or early next day and you remember, it's ok. If I miss a whole pill, my period was messed up. Before this pill I had bad cramping and horrible 7 day periods! I have no side effects, my periods went from super 7 days to very lite 2 days. This pill is a life saver! Part of the reason I am on this pill is for my horrific periods but the other reason is for an estrogen deficiency. I was experiencing hot flashes, night sweats, thinning in hair, etc. at 29 years old, now I have none of that! I recommend this pill...it has changed my life!”

10 / 10
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My Experience January 3, 2020

Natazia (dienogest / estradiol) for Birth Control: “Started taking Natazia about 3-4 months ago. At the beginning, I experienced some breakthrough bleeding. My period would sometimes last for longer than seven days (up to 2 wks). In the 3rd month, I experienced debilitating anxiety and what I think is depression ( never been depressed before). What's interesting is that these feelings seemingly came all at once and rather suddenly. Always been anxious but this particular pill has over amplified my anxiety. Had trouble making simple decisions without worrying about and obsessing over the outcome. Traveling, which I do a lot of, became a serious issue which was never an issue before I started. Pros: my periods are lighter, acne has improved. Yet, the anxiety, depression, and even weight gain is not worth it to me. I'm glad that I detected these signs after only taking for a few months. If I opted to stay on them for longer, dealing with the anxiety, depression, and weight gain would have been unbearable.”

3 / 10
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Giny · Taken for 1 to 6 months September 9, 2019

Natazia (dienogest / estradiol) for Menorrhagia: “I am 47yo and approximately a year ago I've started to have irregular, heavy periods, depression and anxiety. After some tests, I've agreed with my provider that I am in perimenopause and is normal to have some changes in periods, mood and you name it. I tried OTC medications and herbs with some temporary relief. Two months ago, everything got worse so, my provider prescribed Natazia which is a life saver for me. No more irregular and heavy bleeding, my mood and libido returned to normal, less anxiety and depressed mood, and no weight gain. I am very happy with this pill. Unfortunately the co-payment is high..the insurance companies should adjust this...other wise woman with similar problems will not be able to purchase the product and get better. What about EQUALITY my friends??”

10 / 10
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Em0873 November 4, 2018

Natazia (dienogest / estradiol) for Birth Control: “I just started the first month on this pill. I was really anxious starting BC again because I had HORRIBLE experiences with other kinds of pills, including ortho-Cyclin, ortho-tri-Cyclin, Sprintec, etc. all of those pills made me feel constantly on edge and extremely nauseous. I was told to wait it out and suffered for 9 months with nausea and panic attacks almost every day and my skin and periods didn’t even improve. This is the first pill I have taken that I haven’t experienced any side effects! I’ve only been taking it for 2 weeks, but with the others I could tell within a few days. I think this pill is better since the kind of estrogen in it is converted into your “natural” estrogen in your body, plus the dosing increases so gradually the first week. The only downside is that I started to spot for a few days if I’m late by even a few hours, so I have to make sure I take it at the exact same time each day.”

9 / 10
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ladyA00 August 12, 2016

Natazia (dienogest / estradiol) for Birth Control: “I had terrible periods with excruciating pain and HEAVY bleeding. No birth control pill worked. I was depressed every other two weeks. It was a nightmare. I thought maybe I had endo, but a friend suggested Natazia. She had been taking it for a year and her symptoms went away. I asked for it, and my life changed. I tell people that Natazia healed me - no period symptoms, no mood swings, no migraines, no pain! The fact that it's not one does of hormones for one month makes so much sense - why did it take so long for them to develop this! It has different levels of hormones for each part of your cycle, giving you what you need or don't need! Dont give up if you don't see changes immediately- give it at least 3 mos!”

10 / 10
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lost please advise March 11, 2016

Natazia (dienogest / estradiol) for Birth Control: “I had a tough time with my periods since day 1. Always excruciatingly painful, bloating, vomiting, heavy and lengthy 9+days. I had to miss a lot of school and later on had to miss a lot of work. Quality of life was very poor. I always had to plan my life around when my period would be coming because I knew all plans would have to be cancelled. Natazia changed all of that. I have been taking it for 5 years now and these days my periods are super light for 2 days with no pain. Cons.... since I've been on this pill ive noticed my vision has gotten progressively worse, I am moody, I have gained about 10 lbs per year that no amount of diet and exercise seems to be able to fix and finally I have NOsex drive, putting a strain on my relationship”

1 / 10
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Anonymus · Taken for 1 to 6 months February 28, 2020

Natazia (dienogest / estradiol) for Birth Control: “No side effects, like other pills I've been on. The downside, decrease libido, very dry/painful intercourse and having my period for 8-9 days. They are very light compared to my periods when I was not on the pill for 4 years. Debating if the no side effects outweighs the cons.”

6 / 10
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Annelise Gaff September 12, 2016

Natazia (dienogest / estradiol) for Birth Control: “Awful experience. Took Natazia for 5 days and became so depressed and anxious. I would start crying for no reason and have serious mood swings and feel very irritable/annoyed at everyone around me. My vision became very blurry and my eyes were more dry than normal (I have contact lenses). I was nauseous most days and felt very bloated. My migraines came back full force. I do not recommend this pill at all.”

1 / 10
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Brooke · Taken for 6 months to 1 year May 4, 2018

Natazia (dienogest / estradiol) for Menorrhagia: “I was prescribed Natazia because it has an extremely high dose of estrogen, which helped with my menorrhagia and massive clots. However, this pill caused me to experience mini strokes and made my doctors believe I had multiple sclerosis at 18 years old. An MRI showed that I was experiencing hemiplegic migraines and that this pill was the root cause. Do NOT take if you have a family history of migraines or stroke. This pill nearly killed me. But it did stop my period which was good.”

3 / 10
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Anonymous July 28, 2013

Natazia (dienogest / estradiol) for Birth Control: “I have been on Natazia for almost 2 years. For about a year and half I haven't really had a period. Some months its absolutely nothing at all. Occasionally I spot. Last year I told the Gyno she said its nothing to worry about. My skin doesn't break out on this pill. I was on Ortho Tri-cyclen Lo, My skin was terrible. I have gained a lot of weight since on this pill but the clear skin and no period is kind of worth it. I use to get terrible cramps and bleed a lot. Hope this is helpful.”

10 / 10
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Agnes11 · Taken for 5 to 10 years February 13, 2018

Natazia (dienogest / estradiol) for Birth Control: “I switched between 8 different BC pills for 3 years 8 years ago and have been on this one ever since I found it. My periods used to be never ending. They would start heavy and last for weeks to months with only a week or two as a break from the bleeding. My iron and potassium levels were out of control and we were looking for a BC pill that would help control my body's apparent addiction. Natazia was it. I never once had any issue with it. No depression, anxiety, headaches, light head, etc. My insurance without warning decided to not cover the 200-300$ medication over the summer and I had to petition them with several of my doctors to get them to continue to cover it for me. It turns out that most insurance companies looked through all the Natazia reviews and decided that the majority of people taking it feel that it doesn't help them. But I feel like if it doesn't help you, you are obviously going to come off it and try something new.”

10 / 10
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txmere March 25, 2011

Natazia (dienogest / estradiol) for Birth Control: “After Triphasil was removed from the market several years ago, I struggled to find a pill that worked for me. I tried Trivora and Lo-Ovral but my libido completely left me, and I had horrible mood swings most of the month. Eventually, I got off the pill all together. After 3 years off the pill, I needed to get back on because of bad cramps, and my doctor suggested Natazia. It has been 5 months now, and I am thrilled with the results. The first 2 months, I did not have a real period, just some spotting, but now I seem to have leveled out into a predictable cycle. I have a few days of spotting 1 week before the inert pills, then I have a period that literally lasts only a day. No cramps, minimal breast tenderness, and I feel like myself.”

9 / 10
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vic1004 · Taken for 1 to 6 months February 19, 2015

Natazia (dienogest / estradiol) for Birth Control: “I have been on Natazia for almost 2 months. I love it. I switched from being on Yasmin for 3 years. Natazia is a life-changer! My periods are amazing (if periods could be) and I've lost the weight I struggled to lose on Yasmin.”

10 / 10
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kellsbells · Taken for 1 to 6 months April 28, 2014

Natazia (dienogest / estradiol) for Birth Control: “This is my 3rd birth control pill. I've always had long periods (7-9 days) and after my last pill gave me mood swings, NO sex drive, and still long periods with spotting between periods; this pill has fixed all that. My periods are barely 3 days and I have no spotting between periods, which is the best part. Well, that and the fact that it works to prevent pregnancy in 2 ways.”

10 / 10
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Azzzz December 27, 2010

Natazia (dienogest / estradiol) for Birth Control: “Have been on 3 other pills before Natazia (Microgynon 30, Marvelon, and Brevinor). Had many many symptoms with these pills including constant breakthrough bleeding, nausea, vomiting, headaches, increased appetite, bad moods. I thought I would be one of those women who couldn't go on the pill at all. Then I tried this pill (having heard its more "natural" and a four-phase pill) and I cannot believe that I haven't even had any symptoms at all. Nothing, AT ALL! I would seriously recommend this pill if you have had problems with other pills especially regarding breakthrough bleeding.”

10 / 10
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Anonymous · Taken for 1 to 6 months June 11, 2012

Natazia (dienogest / estradiol) for Birth Control: “For someone who has been on 7 different birth control pills, I'm pleased with Natazia. I have had side effects all the way from vomiting/nausea to water retention and mood swings on other pills. I have noticed NO side effects on Natazia thus far; I have been on it for 2 months. I am giving my positive experience on Natazia because I think it's needed. Hopefully it will help others not to prejudge it. Give it a try. And if you're looking for a pill that gives you virtually no period, this will do it!”

10 / 10
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Anonymous November 7, 2010

Natazia (dienogest / estradiol) for Birth Control: “I have been using this pill since September. It is my first time using birth control pills. I am 30 with a beautiful son and my husband does not want any more kids. I spot most of the month. In October, I spotted the first week and a half. Then I began spotting again the last week. This is too much. I did not like being on my period before the pill and it was regular then. I have also had a break out in my face. I did not have acne this bad when I was a teenager. I am not sure if this pill is for me. If things do not change this month I will have to find another pill to try.”

5 / 10
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Quita85 April 10, 2015

Natazia (dienogest / estradiol) for Birth Control: “I was put on Natazia by my Ob about a month ago to stop the growth of my ovarian cyst, heavy periods, & cramping. I did notice I was a bit moody, but it shrank one cyst to half it size. I lost 10lbs in the first month. It lightened my cycle the first four days, but it's day 10 with no end in sight. I decided to stay on it for my cyst though.”

6 / 10
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Dani · Taken for 6 months to 1 year November 11, 2020

Natazia (dienogest / estradiol) for Menorrhagia: “I have been on birth control for the majority of 20 years. Tried every kind. When I got off them, I realized that they had been amplifying my PTSD, anxiety, depression, anger, sadness, everything. I felt normal finally. Well, fast forward to having my first child at 34. C-section caused adenomyosis, endometriosis, heavy bleeding, and polyps. I also started getting more ovarian cysts that wouldn't go away. Eventually after a lot of research, I found Natazia. It's supposed to be the closest to bioidentical available. My mood is normal. I skip the placebos and estrogen only pills after having a 40 day period about 2 or 3 months after starting. Highly recommend taking them like this. Cons: the estrogen still irritates, so I'm still in pain (significantly less though!). Less sexual desire and dryness (not as bad as other pills!). I think its causing hair loss too.”

9 / 10
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Anonymous September 8, 2011

Natazia (dienogest / estradiol) for Birth Control: “This pill didn't give me any of the listed side effects, and my periods were only about 2-3 days (which is very short for me, loved that). If that was all, I would give it a 10, HOWEVER, it completely killed my ability to get aroused (wet), my libido was there and I was very into the intimate moments, but I was very dry ....unlike me. It also made my skin and scalp very dry too, it's like it sucked all the moisture out of my body. I switched to a different pill and the dryness problems went away in about a week. Definitely not the right birth control pill for me.”

2 / 10
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This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare professionals.