Skip to main content

Dienogest / estradiol and Headaches: What Users Say

Brand names: Natazia

Headaches: mentioned by 6 users (8.1%)

Based on user experiences from 74 Dienogest / estradiol reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

bleeding 23.0%
cramps 18.9%
acne 17.6%
weight gain 13.5%
depression 10.8%
mood swings 9.5%
nausea 9.5%
sexual dysfunction 9.5%
spotting 9.5%
headaches 8.1%

Reviews for Dienogest / estradiol

Commonly mentioned side effects
  • Col...
  • November 8, 2018

For Birth Control "I began Natazia at 14. I'm 21, so I've been on it 7 years. I have severe endometriosis, which is why I began the pill to treat it and preserve fertility. I've had laparoscopy. Natazia made my periods very light and short or often disappear. Pre-BC, I had 12-day periods that were incredibly painful and heavy. Now, I rarely bleed more than a day or two, even if I take the placebo. HOWEVER, I believe Natazia has caused incredibly severe and chronic issues for me: appetite disorders, milia around my eyes, severe anxiety, crippling depression, insomnia, exhaustion/tiredness, constant bloating, 10 lbs weight gain, nausea, headaches, nonexistent libido, dull hair, and uneven skin. I am very healthy otherwise, as I am a college athlete and eat a plant-based diet. I really am considering stopping BC altogether, this is truly unbearable. I'd rather bleed for 12 days than feel this way."

3 / 10
Was this helpful?YesNo
35 Report
  • Agn...
  • Taken for 5 to 10 years
  • February 13, 2018

For Birth Control "I switched between 8 different BC pills for 3 years 8 years ago and have been on this one ever since I found it. My periods used to be never-ending. They would start heavy and last for weeks to months, with only a week or two as a break from the bleeding. My iron and potassium levels were out of control, and we were looking for a BC pill that would help control my body's apparent addiction. Natazia was it. I never once had any issue with it. No depression, anxiety, headaches, light-headedness, etc. My insurance, without warning, decided to not cover the $200-300 medication over the summer, and I had to petition them with several of my doctors to get them to continue to cover it for me. It turns out that most insurance companies looked through all the Natazia reviews and decided that the majority of people taking it feel that it doesn't help them. But I feel like if it doesn't help you, you are obviously going to come off it and try something new."

10 / 10
Was this helpful?YesNo
13 Report
  • Azz...
  • December 27, 2010

For Birth Control "Have been on 3 other pills before Natazia (Microgynon 30, Marvelon, and Brevinor). Had many, many symptoms with these pills, including constant breakthrough bleeding, nausea, vomiting, headaches, increased appetite, and bad moods. I thought I would be one of those women who couldn't go on the pill at all. Then I tried this pill (having heard it's more 'natural' and a four-phase pill), and I cannot believe that I haven't even had any symptoms at all. Nothing, AT ALL! I would seriously recommend this pill if you have had problems with other pills, especially regarding breakthrough bleeding."

10 / 10
Was this helpful?YesNo
20 Report

See also:

  • sad...
  • January 9, 2014

For Birth Control "I've been on this for 3 months. I experience heavy bleeding and bad cramping always on the 3rd week of the pill. I have bad headaches every day. I'm a healthy eater, non-smoker, and work out 3-4 days a week. Going to the doctor tomorrow!"

2 / 10
Was this helpful?YesNo
12 Report
  • tha...
  • April 23, 2011

For Birth Control "I took Natazia for 4 months after taking Levora/Portia for 2 years. My libido went WAY UP. In the first 2 months, everything was fine, my period was light, my appetite decreased, and I even lost a little weight. However, in the last 2 months, I had bleeding every 2 weeks. I bled on Days 10-15 exactly like a heavy/regular period. I began getting chest and facial acne and headaches (which are not normal for me). So, after 4 months, I had to switch. The increase in libido was awesome, but it is not so awesome to be 'unavailable' for additional days (beyond the period) each month."

6 / 10
Was this helpful?YesNo
7 Report
  • Ano...
  • Taken for 6 months to 1 year
  • August 24, 2021

For Heavy Menstrual Bleeding "I took Natazia after having it prescribed for heavy bleeding. Before starting, I would bleed through a pad every time I went from a seated to standing position and passing painful, tangerine-sized clots. (Sorry for TMI but trying to be helpful.) I suffered with severe anemia after every cycle due to my period having no end date and sometimes lasting weeks to months. The first two weeks on Natazia, I did notice headaches, breakouts, and a 'meh' emotional state, not depressed or anxious, but I just felt nothing, almost like a robot. After my first month, everything was great, I was back to being as joyful and happy as ever, I had a high sex drive, my acne was alright, and I did notice an increase in discharge (I don't really mind it). Periods lasted 2 days every month, ranging from light to simply spotting. I was on it for around 7 months until stopping a few months ago. I did notice after stopping, I had a few weird side effects and blood pressure issues, but those resolved soon."

8 / 10
Was this helpful?YesNo
1 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.