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Azithromycin for Sinusitis User Reviews (Page 5)

Brand names: Zithromax, Azithromycin Dose Pack, Z-Pak

Reviews for Azithromycin

Commonly mentioned side effects
  • Upd...
  • Taken for less than 1 month
  • March 27, 2022

"I had taken this for my third time, but I spoke too soon. Yes, it did help clear my throat issue, but I came to find out I have chronic sinusitis, and it did nothing to cure that, so I was back to square one. I have come back on here to report a crazy side effect, which I would not categorize as rare, but common (and not even sure if it is mentioned in the fine print). I woke up in the middle of the night with my ears buzzing and ringing so loud! This was seriously freaky to me and scary, but I chalked it up to the fact I was dehydrated, or maybe it was working hard to get rid of the ear infection I had. I drank a cup of water and then closed my nostrils and blew out to pop my ears open, and that helped, and I did not have the ringing again, thank goodness. Therefore, I do believe long-term consistent use and/or abuse can definitely cause an ear ringing problem, but if you take just your dose, this isn’t going to be an issue that stays. I still think this is an amazing drug, and I do trust it."

9 / 10
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1 Report
  • PJa...
  • December 31, 2020

"I have used the Z-pack on and off for years. This time they gave me the generic brand! It always had minimal side effects with the non-generic, but with the generic, it was horrible. Stomach pains, nausea, but the worst was diarrhea. I would NEVER take this generic brand again."

3 / 10
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1 Report
  • Ana...
  • Taken for less than 1 month
  • January 13, 2018

"Side effects: headache, dizziness, and really tired. I have eye pain, no hunger, stomach pain, body chills, and nervousness. I feel like I'm gonna get sick. I'm on my 3rd day of this medication, and my sinus, well my nose, is still stuffy sometimes. Haven't seen a lot of change. I have 3 more days to go, let's see, because amoxicillin didn't work for me :(."

4 / 10
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2 Report

Frequently asked questions

  • Non...
  • Taken for less than 1 month
  • March 12, 2022

"First time I've been prescribed azithromycin for my sinus infection, and it completely sucks for it compared to my typical amoxicillin. Three days in on the Z-Pak and nothing, still have a fever, no change in sinus pressure, and now a splitting headache with a large amount of gas. At least with amoxicillin by the third day, I would feel better, this, nothing. I'll continue treatment just to see, but highly doubt it."

1 / 10
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  • Gab...
  • Taken for less than 1 month
  • November 6, 2021

"I had a pretty severe sinus infection and was prescribed this to help with my symptoms. It definitely did its job, but oh my God. The worst stomach pain I’ve ever had in my life. I never get side effects from medicine, and I have had to take quite a good amount, but wow this was bad. I have no idea why I reacted with this antibiotic, but it was so bad that it would last the entire day any time I ate, and I was afraid to eat on it. And I never have stomach issues, so this was very hard for me. It does what it needs to, but I won’t lie it was some of the worst pain I’ve ever dealt with."

6 / 10
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  • Sic...
  • Taken for less than 1 month
  • November 1, 2017

"Took the first two pills for a sinus and ear infection that I’ve had for months. Tried holistic stuff, but only temporary relief. I used to use this all the time and never once had reactions. Most generics usually turn to rubbish, this did too. Had instantaneous stomach bloating and indigestion (took with GF cereal), skin red and itchy, and worst of all, I’ve suddenly got flu-like symptoms. Feel like trash. 99.4 temp, but feel like I’m on fire. Just a little advice here at the end for sufferers of chronic sinus infections and the like. Just found out why I’m sick all the time: IGG subclass deficiencies. I’m prone to get sinus infections and others. Have a rheumatologist or immunologist check your immune system. Finally found out why I’m so sickly."

3 / 10
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  • jud...
  • Taken for less than 1 month
  • September 29, 2021

"Was prescribed it without a nasal lavage. Do not think I even have a sinus infection, but chronic perennial allergic rhinitis and too many surgeries. Nothing after a 3-day and then one-a-week regime. The only side effect, insomnia, but it was bad."

3 / 10
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More FAQ

  • Del...
  • February 20, 2018

"I am on azithromycin for 4 days for a sinus infection. The first day I had to take two 250 mg pills, within an hour and a half, my stomach started cramping up. I got 4 more days, I will be finished with this antibiotic."

8 / 10
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2 Report
  • Sic...
  • August 1, 2016

"I'm only rating it a 3 so far as I'm on day 2. I went to urgent care pregnant with a chronic cough. I usually get sinus infections, but since I'm pregnant, they couldn't X-ray me. Day 1, within a half hour, I felt sharp stomach pains, and my stomach was rumbling. It ended up being diarrhea. I slept just fine at night. I woke up with my cough again. I think my cough improved a little bit on day 2, but I am still coughing a lot. I experienced sharp pains in my stomach and through my vagina. I'm hoping for more progress with this medicine. As is, I was very hesitant to take it since I'm pregnant, but if there is an induction, I wanted to not pass it along to the baby."

3 / 10
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3 Report
  • Tra...
  • Taken for less than 1 month
  • April 8, 2017

Azithromycin "This drug worked after 5 days on my sinus infection. On the 6th day, I experienced vomiting, dizziness, stomach cramps, constipation, black stool, hypertension, fast beating of the heart, low energy, hives on my face, headaches, swollen eyelids, and dark circles under my eyes. Day 11 after taking the last dose, still experiencing a fast heartbeat, swelling in my feet, and hives on my face. Low energy."

4 / 10
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6 Report
  • jen...
  • February 6, 2014

Azithromycin "Many sinus infections over the years. This knocks it out in 3 days compared to 10."

10 / 10
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104 Report
  • Pas...
  • December 26, 2015

Azithromycin "After trying other antibiotics, this was the only one that worked. The doctor tried to tell me it would not work for sinusitis. It is the only antibiotic that takes it away for me."

10 / 10
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59 Report
  • rag...
  • November 13, 2008

Azithromycin "The only antibiotic that always works on my recurring sinus infections. Easy on the stomach also."

10 / 10
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61 Report
  • and...
  • March 5, 2013

Azithromycin "I am one of the few that have not had a good experience. High anxiety because my heart won't slow down, bad headache, little nausea, and loose stool. I'm going tomorrow to get different antibiotics."

2 / 10
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51 Report
  • Anonymous
  • September 18, 2008

Azithromycin "After I take the first dose (2 pills), within 8 to 10 hours, I feel 50% better. It usually does not take more than 4 days to be well. This is a great medication for sinusitis."

10 / 10
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55 Report
  • Ano...
  • January 10, 2010

Azithromycin "I used this for every infection, now the sad part is I am resistant. I used the whole 5-day dose, felt a lot better, then the infection came back a week later."

8 / 10
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41 Report
  • Anonymous
  • January 17, 2012

"I'm on Day 4. My sinus infection is much better, but the diarrhea and upset stomach are bad."

8 / 10
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35 Report
  • Anonymous
  • February 2, 2016

Azithromycin "It worked, however, on the fifth day of taking it, I had supraventricular tachycardia (SVT). Later found out there was a study out that confirmed heart rhythm issues."

7 / 10
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28 Report
  • Anonymous
  • November 25, 2009

Azithromycin "I have taken this many times, and it clears up the problem with no side effects at all."

10 / 10
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37 Report
  • mei...
  • Taken for less than 1 month
  • July 30, 2012

"It is useful, but I have headaches during usage."

6 / 10
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32 Report
  • yan...
  • December 9, 2013

Azithromycin "Could be effective, not sure. Side effects from three-day Pak: headache, nausea, anxiety, sore throat, chills, tired, a feeling of being very unwell."

7 / 10
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41 Report
  • Wil...
  • Taken for less than 1 month
  • October 10, 2019

"I've done taking the med, and I don't feel any improvement. I still have sinus congestion, headache, and pressure in the ears. So, I have to go see a doctor again."

1 / 10
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15 Report
  • And...
  • Taken for less than 1 month
  • March 8, 2018

Azithromycin "Doc put me on a 5-day dosage to treat a sinus infection, didn't miss a day, finished the dosage, and I still have a sinus infection."

1 / 10
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16 Report
  • Ric...
  • October 17, 2015

"I suffer from chronic sinusitis. Allergic to doxycycline. Azithromycin is a lifesaver. It's great."

10 / 10
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17 Report
  • tha...
  • July 18, 2009

Azithromycin "This medicine is very good for my sinus, I feel very well now."

10 / 10
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24 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.

Learn more about Sinusitis

Care guides

Symptoms and treatments

Medicine.com guides (external)