How long does azithromycin stay in your system after you finish taking it?
Medically reviewed by Drugs.com. Last updated on Aug 27, 2020.
Azithromycin will be in your system for around 15.5 days, after the last dose.
Azithromycin has an elimination half-life of 68 hours. The prolonged terminal half-life is thought to be due to extensive uptake and subsequent release of drug from tissues.
It takes around 5.5 x elimination half life's for a medicine to be out of your system. Therefore it would take 374 hours about 15.5 days (5.5 x 68 hours) for it to be eliminated from the system. So it'll be in your system for that period of time, after the last dose.
Other factors to consider:
1. How much and how often you have taken the drug.
2. Your metabolic rate – a slower metabolism will increase the time a drug remains in your system.
3. Your age and health – older age and poor health will generally increase the time the drug stays in your system.
4. Body mass – generally the bigger you are the longer a drug will remain in your system.
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