Amoxicillin / clarithromycin / lansoprazole and Fatigue: What Users Say

• Mac...
• Taken for less than 1 month
• May 8, 2019

Amoxicillin / clarithromycin / lansoprazole for Helicobacter Pylori Infection "Have completed the 14-day Prevpac treatment. I started the first day expecting horrible side effects. That didn't happen. I had a few nausea moments that lasted only seconds. My bowel movements were totally normal. I will say I became very fatigued, but I slept well and generally felt very good during the entire 14 days. I did have a bit of depression, but I assumed it was caused by the treatment, so I just ignored that. It was 8 pills a day, plus a probiotic. That's 126 pills in two weeks! As you can see, it didn't affect my mathematical skills! Today is the 2nd day pill free and done with Prevpac. I don't remember feeling this good in a long while. The treatment appears to have worked extremely well. So, do I recommend Prevpac - that is a resounding YES. And the best of luck to you all."

• Joe...
• March 30, 2019

Amoxicillin / clarithromycin / lansoprazole for Helicobacter Pylori Infection "I’m on day 9 of this horrible medicine. It’s horrible to me because I got hit with side effects of diarrhea, fatigue, loss of appetite, followed by anxiety and even an episode of depression, which I’m still recovering from. It’s scary to deal with, but I haven’t had heartburn since beginning this and have been able to eat. Before taking the medicine, the infection made me not even want to chew. It is very rough, but I’m almost at the end, and that’s what’s helping me pull through all this. Some tips are to take a probiotic like lactobacillus to help with diarrhea (it’s helped somewhat for me), and avoid any acidic foods, sugars, and salty stuff. I’ve searched through many other reviews of this medicine to make sure I’m not the only one with anxiety and panic attacks. If you take this medicine and go through serious anxiety, please talk to someone about your thoughts, it’ll help. Before this medicine, I’ve never had anxiety or depression. Those side effects are killing me."

• Ban...
• Taken for less than 1 month
• September 12, 2020

For Helicobacter Pylori Infection "I'm now on day 3 of my triple antibiotic treatment, amoxicillin/clarithromycin/lansoprazole, for H. pylori. I was first diagnosed with H. pylori infection 6 months ago, but I refused treatment because I was asymptomatic. Once the symptoms kicked in, I decided to be brave and take the treatment. I've had the nasty taste in my mouth and a short bout of diarrhea. The worst part for me is the fatigue. I can barely keep my eyes open! I also have very little appetite. I try to take tons of probiotics (kefir, yogurt, and kimchi) all day in between my pills, and they are helping a lot. I'm bloated and exhausted, but I feel positive that I'll make it through the regimen. Good luck, everyone!"

• Pai...
• Taken for less than 1 month
• May 3, 2019

Amoxicillin / clarithromycin / lansoprazole for Helicobacter Pylori Infection "So, started off pretty confident. No problems here, what's the big deal? Day 7, projectile vomiting for 24 hours, followed by fatigue, my bits felt on fire, couldn't get out of bed, couldn't work, no appetite, should have gone to the ER for IV fluids. Finished the last dose the night before, nurse said the cure often feels worse than the bug (but the bug can increase the risk of stomach cancer). I hope H. Pylori is gone because I'm really not sure I can do it again. Of course, everyone's experiences are different, wishing you all the best."

• Mis...
• Taken for less than 1 month
• July 27, 2019

For Helicobacter Pylori Infection "Well, let me begin by saying I never experienced heartburn or had symptoms prior to the endoscopy that found the H. Pylori, so to be perfectly honest, the treatment has been a bit brutal. The metallic taste in my mouth is so bad if I actually do sleep, it wakes me and I am extremely nauseated. Diarrhea also. Fatigue, a definite. A lot of burping now, and now I seem to be actually experiencing heartburn. The one positive I will say is I noticed the bloating I have had for several years, which honestly I thought was my stomach, is going down significantly. Also, yogurt is your friend, I find it helps with the metallic taste. I have a few more days to go, so I hope it’s worth it! Hang in there, there’s light at the end of the tunnel."

• Suf...
• September 12, 2019

For Helicobacter Pylori Infection "Hang in there, everyone, on this triple treatment for H. pylori. I just finished my 14th and last day yesterday. It was a horrible experience! I gained 3.2 lbs the first week, and I was eating my usual Weight Watchers healthy food. The only thing was I had no energy to exercise and had a few extra fruits! I still have that horrible taste in my mouth and still have pain even though I'm done with the meds, ugh! After my Weight Watchers weigh-in today, I couldn't stop eating. Even though I had lost 1.9 lbs of the weight I gained last week, I couldn't stop eating, I just wanted to make the taste go away! I now have to wait one month before doing the breath test to see if it's gone, and I pray for everyone, including myself, that we never, ever have to do this horrible treatment again."

• Fin...
• August 15, 2016

Amoxicillin / clarithromycin / lansoprazole for Helicobacter Pylori Infection "Reading these reviews, and at least, good to know I'm not the only one who has struggled with H. Pylori. Saw multiple doctors...all brushed it off. Was finally scheduled for an upper endoscopy. Prior to the appt, felt the worst ever. Symptoms over months had progressed from stomach pain and acid reflux (managed with 40 mg Prilosec twice a day) to fatigue, burping, chest pains, liver and spleen pain, feeling confused and delirious, diarrhea. Finally, a walk-in clinic doctor ordered a stool sample test. I'm on day 3 of Prevpac and feeling better. Metallic taste in the AM but goes away. Loading up on probiotics...highly recommended. Definitely need to take with food. I'll have to retest in about a month, but hoping this works! Best of luck to everyone!!!"

• SAT...
• September 24, 2013

Amoxicillin / clarithromycin / lansoprazole for Helicobacter Pylori Infection "I'm usually very regular, so when I started experiencing stomach discomfort-bloating, constipation, lots of gas-I headed straight to my doctor. I did indeed have H. pylori and was given the Prevpac 14-day treatment. After reading what seemed like pages of negative reviews and side effects, I was hesitant to start the regimen and made a deal with myself that if it didn't work out for me, I'd go toward a more holistic route. I'm on Day 13, and overall I had a positive experience. The first few days I was fatigued, and that eventually went away. I did get a bad taste in my mouth after an hour of taking the medicine. I'm regular again and feel much better. I also took probiotics and cut out sugar, dairy, and gluten, which I think helped as well."

• Peb...
• September 4, 2013

Amoxicillin / clarithromycin / lansoprazole for Helicobacter Pylori Infection "I'm on my fourth day of using the Prevpac for H. pylori infection, which was discovered during a medical procedure (colonoscopy and endoscopy). I was experiencing stomach discomfort (throbbing alternating aches from left to right), which prompted me to have these procedures. Day one: I felt tired and experienced severe stomach pain, including bloating, but it (stomach pain) eventually subsided. Day two: minor stomach pain and little bloating. Day three: I did not experience any pain, but I had the metallic taste and felt fatigued. I have noticed that my bowels are larger (sorry for the extra information) than normal. Details to take into consideration: female and a minority."

• Jja...
• Taken for less than 1 month
• October 9, 2019

For Helicobacter Pylori Infection "I'm having almost 90% of the side effects: nausea, headache, diarrhea, fatigue, loss of appetite. My depression is amplified, and do not get me started on the bitter taste in my mouth. I am dying here and have 6 more days to go. I am missing work and have been in bed almost all day, except when eating. Other than that, I just don't want to move. Hope this treatment works because I cannot take any more of this."

• Mel...
• May 9, 2016

Amoxicillin / clarithromycin / lansoprazole for Helicobacter Pylori Infection "For the first week, I was in excruciating pain: nausea, severe abdominal pain, diarrhea, sweating, insomnia, confusion, extreme exhaustion and fatigue, battery acid taste in my mouth, etc. I reached out to my doctor and pharmacist who offered absolutely no help. Through research, I found that taking probiotics/yogurt helps with EVERYTHING, stay as hydrated as you can. I ate a lot of ramen noodles to compensate for actual food/water since my appetite was nonexistent. I didn't think I was going to be able to finish the treatment. If I test positive again, I'm going with natural remedies."

• Mel...
• May 9, 2016

Amoxicillin / clarithromycin / lansoprazole for Helicobacter Pylori Infection "For the first week, I was in excruciating pain: nausea, severe abdominal pain, diarrhea, sweating, insomnia, confusion, extreme exhaustion and fatigue, battery acid taste in my mouth, etc. I reached out to my doctor and pharmacist who offered absolutely no help. Through research, I found that taking probiotics/yogurt helps with EVERYTHING, stay as hydrated as you can. I ate a lot of ramen noodles to compensate for actual food/water since my appetite was nonexistent. I didn't think I was going to be able to finish the treatment. If I test positive again, I'm going with natural remedies."

• Har...
• December 5, 2020

Amoxicillin / clarithromycin / lansoprazole for Helicobacter Pylori Infection "I am so happy I found this site!!! I am on day 10 of the HPAC (amoxicillin/clarithromycin/lansoprazole). The first few days were great. Felt better than I have in the last year. But on day 8, I started to feel ill. Terrible, terrible nausea, stomach ache, headache, loss of energy, can’t sleep, hate food, metallic taste... Thought of stopping treatment, but after reading other posts, I will take some probiotics, yogurt, Gravol, and hope it gets me through the next 4 days. I found if you need quick relief from the stomach pain and nausea for an hour, Gaviscon will help. Hope this works. Could not go through another course of treatment."

• Dog...
• Taken for less than 1 month
• September 12, 2018

For Helicobacter Pylori Infection "Was diagnosed with H. pylori and given amoxicillin, clarithromycin, and omeprazole to take for 14 days. First day, my only side effect was extreme fatigue. Second day, no side effect except a headache. By the 5th day, I started to experience diarrhea. That was my only side effect and the bitter taste in my mouth off and on for the rest of my treatment. I did do as others mentioned and took a probiotic between doses. Make sure you remember to throw away your toothbrushes and buy new ones after treatment! All in all, treatment wasn't bad. Don't let other people's experiences scare you."

• Lak...
• Taken for less than 1 month
• November 30, 2014

For Helicobacter Pylori Infection "I'm on my day 4. It's making me feel dizzy, tired, and fatigued. This is bad enough, but the worst is that it tastes bitter and wakes me up a few times because of that. I drink water, but the bitter taste does not go away."

• Mar...
• April 30, 2015

Amoxicillin / clarithromycin / lansoprazole for Helicobacter Pylori Infection "I had acute gastritis and went to the ER to get IV fluids. While there, they ran a test for H. pylori and it was positive. My only symptoms prior to the ER visit were frequent heartburn. I was given a prescription for Biaxin, amoxicillin, and omeprazole for 14 days. I got online and was horrified by the reviews. I delayed starting my meds. The first three days were hell on earth: nausea, fatigue, anxiety. I learned very quickly to eat with each dose. I had the metallic taste up until day 10, and then it went away. I'm wrapping up day 12, and while the treatment was tough in the beginning, it is doable. My GI is going to do an EGD in 60 days. I was also told to continue omeprazole for 2 months to heal ulcers and combat rebound reflux. Feeling better!"

• Ace...
• Taken for less than 1 month
• December 15, 2020

For Helicobacter Pylori Infection "Day 2 of H. pylori kit. At first, I thought something must be wrong with the drugs because they made my symptoms worse. I felt really terrible after day 1. But after reading reviews, I feel I'm not alone and will get through the treatment. My symptoms are bloating, passing gas, nausea, metallic aftertaste, fatigue, cramps, and excruciating pain in my tummy."

• KMa...
• May 28, 2020

For Helicobacter Pylori Infection "Be your own advocate. I have had anemia, which leaves me fatigued for a very long time. I have suffered from severe bloating, pain, belching, and flatulence. I made an appointment a few weeks ago because I was having difficulty breathing and had severe bloating. I thought it was the arthritis. The blood work showed that my iron levels were 6 micrograms per deciliter. Normal levels for women range from 26 to 170. She has been prescribing me iron supplements for three years. On this particular visit, she sent me for some blood work, and it came back positive for Helicobacter. I was so glad to have a name that had caused me so much pain over the years. Since starting the medication, I have had pretty much all the side effects, including metallic taste in my mouth, severe bloating and pain, vivid dreams, insomnia, diarrhea, and most recently, itching. I am on day 12 of 14 and am looking forward to getting this nasty bacteria out of my system. Chewing gum has helped with the metallic taste."

• Len...
• October 3, 2020

For Helicobacter Pylori Infection "I too have H. pylori, my symptoms were fatigue and a periodic bad taste in my mouth. Since I was on medication for my liver, I called and asked, “Are the liver meds causing this?” I was directed to Quest for a breath test. Proof positive! The three meds in conjunction are disgusting! In previous reads, I agree the road to wellness is far worse than the symptoms!"

• Amy...
• September 3, 2018

For Helicobacter Pylori Infection "I started treatment 3 days ago, and it hasn't been bad at all. I'm doing the omeprazole, amoxicillin, clarithromycin treatment. First day, first dose, I experienced a little bit of nausea, but nothing bad enough to make me vomit. It came and went, and I did experience extreme fatigue. My entire body was weak and tired. After a nap, I felt fine! I ate Activia yogurt 4 hours after taking it. It also caused a pretty bad migraine. The second dose wasn't bad at all, I started to experience the nasty taste in my mouth, which isn't even that bad, and it only lasted about 5 minutes. It tastes like when a pill dissolves in your mouth, but after drinking water, it went away. On the 2nd day, the same thing: fatigue for about 2 hours and a migraine... nothing that bad at all. On day 3, a slight headache and a few pains in my gut that come and go. Again, nothing that affected my daily life. No diarrhea yet, but I am constipated! I've been eating Activia yogurt twice daily, which has been a huge help. I'm also taking Zofran to prevent the nausea."

• Nei...
• June 18, 2016

For Helicobacter Pylori Infection "I was placed on clarithromycin to get rid of my strep. I'm extremely allergic to penicillin, so this seemed like the best option. I was warned about a metallic taste that may occur and insomnia. I did indeed get both, but loose stool (not so bad), sweating, weirdly vivid dreams (much like those you get on malaria medication), loss of appetite, fatigue, and gas (burping and the other kind). It wasn't that bad, and so far it's very helpful in clearing up my strep. I would 100% recommend this to anyone!"

• Van...
• January 17, 2021

For Helicobacter Pylori Infection "I have been given 5-day triple H. pylori therapy. And been feeling sick since day 1. Had all the side effects: diarrhea, vomiting, fatigue, metallic taste in mouth, just unable to function. Today is day 5, and I am glad it’s getting over. But if someone can please advise how they feel after the treatment is over?"

• Mic...
• Taken for less than 1 month
• January 23, 2021

For Helicobacter Pylori Infection "One of the worst medical combinations ever. I hope pharmaceuticals can come up with something better. For now, I quit. Extreme fatigue, bitter taste, I have a fever, chills, dizziness, bloating, cannot even sleep. In day to, but I can’t continue anymore."

• Ind...
• Taken for less than 1 month
• April 28, 2022

For Helicobacter Pylori Infection "I am on day 4 and unsure if I can continue the course. Since day one, I have had fatigue, severe nausea, and a horrible taste in my mouth as if I just chewed up a Tylenol. I take the meds with food and have taken probiotics, but I am still miserable. Last night was the worst, I woke up and felt horrendous - had a migraine, extreme nausea, overwhelming bad taste, extreme weakness, chills, vomited 3 times. I’m not sure if I have ever felt so bad. I was going to give up this morning, but have pushed myself to continue. The days seem to be better than the nights, but I am praying tonight will go better than last. From reading the other comments, the drugs apparently affect people differently, but I have been an unlucky one. My mother had H. pylori and was treated in the early 90s. She couldn’t make it through the drug regimen and has struggled ever since with heartburn, acid reflux, and ulcers, so I am going to do my best to keep going."

• Ash...
• Taken for less than 1 month
• November 4, 2020

For Helicobacter Pylori Infection "Extreme fatigue after first dose. Improved over hours. Very slight nausea. With second dose came the famous nasty mouth taste and a dull ache in stomach. No diarrhea."