Amoxicillin / Clarithromycin / Lansoprazole Dosage
Medically reviewed on January 22, 2018.
Applies to the following strengths: 500 mg-500 mg-30 mg
Usual Adult Dose for:
Additional dosage information:
Usual Adult Dose for Helicobacter pylori Infection
Amoxicillin 1000 mg-clarithromycin 500 mg-lansoprazole 30 mg orally 2 times a day
-Duration of therapy: 10 to 14 days
Comment: This drug should be taken in the morning and evening.
Use: Treatment of patients with Helicobacter pylori infection and duodenal ulcer disease to eradicate H pylori
Renal Dose Adjustments
Mild to moderate renal dysfunction: No adjustment recommended.
Severe renal dysfunction (less than 30 mL/min): Not recommended.
Acute interstitial nephritis (AIN): Discontinue treatment in patients who develop AIN.
Liver Dose Adjustments
Liver dysfunction and normal renal function: No adjustment recommended.
Liver dysfunction with renal dysfunction: Decrease the dose and/or prolong the dosing interval.
Signs/symptoms of hepatitis: Discontinue clarithromycin immediately
Safety and efficacy have not been established in pediatric patients.
Consult WARNINGS section for additional precautions.
Data not available
-Patients should take each dose before meals.
-The pills should be swallowed whole.
Storage requirements: Protect from light and moisture.
-Eradication of H pylori reduces the risk of duodenal ulcer recurrence.
-This drug may be used in patients with active or a one-year history of duodenal ulcer.
-Hepatic: Hepatic function tests
-Hematologic: Hematopoietic function tests
-Renal: Renal function tests
-Tell patients that it is important to complete the full regimen.
-Instruct patients to seek medical attention if signs/symptoms of hypersensitivity, Clostridium difficile-associated diarrhea, hypomagnesemia, or systemic cutaneous lupus erythematosus occur.
-Inform patients that this drug may cause drowsiness, dizziness, vertigo, and/or visual disturbances. They should avoid driving or operating machinery until the full effects of the drug are seen.
-Advise patients to speak to their healthcare provider if they become pregnant, intend to become pregnant, or are breastfeeding.
More about amoxicillin/clarithromycin/lansoprazole
- Amoxicillin/clarithromycin/lansoprazole Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Español
- 79 Reviews
- Drug class: H. pylori eradication agents
- Amoxicillin, clarithromycin, and lansoprazole
- Lansoprazole, Amoxicillin, and Clarithromycin
- Lansoprazole, amoxicillin, and clarithromycin (Advanced Reading)
Other brands: Prevpac
- Lansoprazole, Amoxicillin and Clarithromycin (FDA)
- Lansoprazole, Amoxicillin, and Clarithromycin (Wolters Kluwer)