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Prevpac

Generic name: amoxicillin, clarithromycin, and lansoprazolea-MOX-i-SIL-in, kla-RITH-roe-MYE-sin, LAN-soe-PRA-zole ]
Drug class: H. pylori eradication agents

Medically reviewed by Drugs.com on Aug 17, 2023. Written by Cerner Multum.

What is Prevpac?

Amoxicillin is a penicillin antibiotic. Clarithromycin is a macrolide antibiotic. These antibiotics fight bacteria in the body.

Lansoprazole decreases the amount of acid produced in the stomach.

Prevpac is a combination medicine used in people with Helicobacter pylori (H. pylori) infection and stomach ulcers. Treating H. pylori infection can help prevent future stomach ulcers.

Prevpac may also be used for purposes not listed in this medication guide.

Prevpac side effects

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes.

Prevpac may cause serious side effects. Call your doctor at once if you have:

Serious side effects may be more likely in older adults.

Common side effects of Prevpac may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings

You should not take Prevpac if you've ever had a severe allergic reaction to certain antibiotics, if you've had certain heart rhythm disorders, or if you've had liver problems caused by taking clarithromycin.

Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact, and some drugs should not be used together.

Before taking this medicine

You should not take this medicine if you are allergic to amoxicillin (Amoxil), clarithromycin (Biaxin), or lansoprazole (Prevacid), or if:

Some medicines can cause unwanted or dangerous effects when used with Prevpac. Your doctor may change your treatment plan if you also use:

Tell your doctor if you have ever had:

You may be more likely to have a broken bone while taking this medicine long term or more than once per day. Talk with your doctor about ways to keep your bones healthy.

This medicine may harm an unborn baby. Use effective birth control to prevent pregnancy, and tell your doctor if you become pregnant.

Amoxicillin can make birth control pills less effective. Ask your doctor about using a non-hormonal birth control (condom, diaphragm with spermicide) to prevent pregnancy.

You should not breast-feed while using this medicine.

This medicine is not approved for use by anyone younger than 18 years old.

How should I take amoxicillin, clarithromycin, and lansoprazole?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Take Prevpac twice daily before you eat, unless your doctor tells you otherwise.

Swallow each pill whole and do not crush, chew, break, or open it.

Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. This medicine will not treat a viral infection such as the flu or a common cold.

This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using Prevpac.

Store at room temperature, away from moisture, heat, and light.

omeprazole, amoxicillin, pantoprazole, metronidazole, esomeprazole, Protonix

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Prevpac?

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor before using anti-diarrhea medicine.

What other drugs will affect Prevpac?

If you take any of the following medicines, take them separately:

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Clarithromycin can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV.

Tell your doctor about all your current medicines. Many drugs can affect Prevpac, especially:

This list is not complete and many other drugs may affect Prevpac. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Does Prevpac interact with my other drugs?

Enter medications to view a detailed interaction report using our Drug Interaction Checker.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.