Praluent for High Cholesterol User Reviews (Page 4)

• Dia...
• Taken for 1 to 2 years
• April 11, 2024

"I’ve been on Praluent for over 2 years and have not had any side effects. I take the injection every 2 weeks, and all cholesterol levels are very good. If I had read all of these negative comments before using this medicine, I would’ve been petrified to try it."

• Mik...
• Taken for 2 to 5 years
• October 5, 2020

"After having a heart attack two years ago, my cardio doctor put me on Praluent, painless injections every two weeks in my legs, along with daily 20 mg Atorvastatin (Lipitor). Together, they both have lowered my bad LDL from 250 down to 25. I'm a 73-year-old man. I'm very happy with the results. I don't notice any side effects. I'm also happy my Mutual of Omaha drug plan Plus, which covers most of the cost 2020/2021. I'm waiting for the FDA to approve Inclisiran, twice-a-year injections, which will be much cheaper."

• Anonymous
• Taken for 1 to 6 months
• May 30, 2018

"I'm a 54-year-old male, average weight, healthy active lifestyle but diagnosed with hyperlipidemia. Statin drug intolerant. Been on Praluent 6 weeks. LDL went from 212 to 57, HDL from 36 to 44. Negative side effects at all. Fantastic results!"

• Jra...
• Taken for 5 to 10 years
• January 24, 2019

"Awesome stuff for me. No side effects. Cut the pravastatin in half: 40 mg pravastatin 1x daily plus 75 mg alirocumab every other week. HDL down from 399 to 85 mg/dl. Still taking the other stuff. Livolo works fairly well, but not like this. Can't tolerate ACE inhibitors, and some med put a bruise across my back within three days: instant kidney damage. Now Blue Cross wants to deny me the only med combo I could tolerate. Actually, Prime Therapeutics is doing that. Forwarding their denial to cardio and via my attorney to OAG and the state insurance board. After one 4x CABG, 3 stents, and 2 MI. Bilateral endarterectomy and original LDL around 400. I think my widow will be a millionaire as for me. We can prove this is the best and most correct treatment plan, and it did work for about 5 years until they decided they should play doctor..."

• Luv...
• Taken for 6 months to 1 year
• March 14, 2025

"I've been on Praluent 150 mg/ml every two weeks for approximately 6 months to lower my cholesterol. Was previously on statins, but the side effects for me got worse over time (muscle cramps, fatigue, brain fog). Praluent has worked well in getting my cholesterol numbers in the normal range, but I've experienced hoarseness, stuffy nose, some muscle cramps in lower legs and feet. I also have periods of strong and rapid heartbeat, and my blood pressure has been creeping up. I notice the symptoms more in the first few days after the injection, and they get better within 5 to 7 days. I'm intolerant to a lot of medications, and my statin intolerance got worse over time. I'm hoping the same is not true for Praluent. My cardiologist (who is the medical director of a prominent cardiology center in my city) said she is aware of the cramps, hoarseness, and nasal congestion as side effects, but not the rapid heartbeat or higher blood pressure. Yet I see a lot of similar reactions in these reviews."

• Hap...
• Taken for 2 to 5 years
• February 1, 2021

"I'm a 73-year-old man, and I've been doing the 75 mg Praluent injections now for almost 4 years with no side effects. My LDL that I get tested every 6 months is a very low 24 thanks to Praluent. When I had my heart attack 5 years ago, my LDL was a very high 250. I'm happy that my CVS Silverscript Plus pays for most of the cost. I also take 20 mg Atorvastatin daily. The painless Praluent auto injector takes about 5 seconds to inject after warming it up and pushing the auto injector button. The only thing I don't like is the high cost and having to keep the Praluent refrigerated before use. For me, there is no pain or bleeding at the injection site, which is my leg."

• DG ...
• Taken for 1 to 6 months
• July 16, 2024

"Allergic to statins. Severe thigh cramping with all of them. Unbearable. Tried Praluent with nearly immediate results. Cholesterol went from very high to perfectly normal after only one or two injections. No side effects. Downside was that price became prohibitive after a few refills."

• Anonymous
• Taken for 5 to 10 years
• January 31, 2024

"Fifteen years ago I had two stents as I was suffering from blocked arteries and terrible angina. I was only 43 years old. I took statins for years, as much as my body could stand, as I suffered from insane muscle pain to the point where I could hardly walk. Because of this, my statin use dwindled to once or twice a week. Five years ago, with my cholesterol high again, I had a minor heart attack. I was then given Praluent, and my gosh, what a savior! Cholesterol levels down to recommended levels and no side effects. I would probably say, without exaggeration, that this drug saved me!"

• GEB...
• Taken for 6 months to 1 year
• August 3, 2023

"Fatigue, lethargy, developed varicose veins in both inner thighs best described as parallel mirror twins. The breaks were discovered during a routine annual screening by my surgeon. The tears were serious. My doctor was concerned because previous procedures on legs were minor. My cholesterol was reduced by one hundred points. My memory improved... recall... somewhat. The medicine is brutal and fatiguing. Didn't realize how draining it was until it was interrupted. My energy returned. My dosage was 150 ml injection twice monthly."

• Ken...
• Taken for less than 1 month
• December 27, 2021

"1st injection was so dangerous for me, my throat started closing, my airway and barely could breathe, I broke out in large hives all over my body with severe itching. Wife rushed me to hospital treatment to take the swelling down, and by 24 hours later, the hives were still there with itching. Took about 4 days of misery for it to go away. What a bunch of poison. Stay away from this bad drug."

• Mar...
• Taken for 1 to 6 months
• June 6, 2023

"I injected the 1st dose of Praluent and had no side effects, and 2 weeks later I injected the second dose. Three hours later, my whole body was experiencing terrible cramping, headaches, fever, and chills. Two days later, I was in the hospital with pneumonia (never in my life had I had pneumonia), UTI infection. I haven’t had a UTI infection in over 25 years, never before had a potassium problem, and while in the hospital, it went down."

• Syd...
• Taken for 5 to 10 years
• April 29, 2024

"I have been using Praluent consistently since 2018 (5 1/2 years) and have not experienced one side effect from this drug. My cholesterol count reduced substantially within two months and has been maintained well within acceptable levels, ongoing. I have had annual visits to the prescribing endocrinologist, complete with blood work analysis, and all measurements have been satisfactory. Prior to being prescribed Praluent, my cholesterol count was considered ultra-high, and I had to be taken off statins as they caused memory loss. Praluent has been far more effective in reducing cholesterol and has done so with no side effects."

• Ssb...
• Taken for less than 1 month
• June 8, 2023

"I have had a CV event and have very high LDL and high LPa and cannot tolerate statins. I started on Praluent and was fine right after the injection. But the first night I woke up with a very swollen tongue and lips and an extremely dry mouth and throat. Took 1/2 Benadryl, which seemed to resolve. But over the next few days, I would experience bouts of extremely high BP and flushing of my face and chest (I tend to have low BP, so this was very odd). High BP and flushing seemed to occur after any exertion, followed by extreme tiredness for a few weeks, and my doctor told me not to take the next dose. Additionally, I have had very unusual headaches, odd bruising, as well as pinpoint bleeding under my skin and bleeding (large thick clots of blood) from my nose. If I got bit by an insect, I would have rubbery clots of blood on my skin. All very strange, and I will be glad when this med has worked its way out of my system (about 40 days). FYI, I do have a lot of sensitivity to many meds, so I am not surprised."

• Boo...
• Taken for 5 to 10 years
• April 16, 2023

"Five years later, I experienced a stroke at the age of 54. Due to being considered high-risk, I was prescribed Praluent, which was believed to be the wonder drug for me. However, I have progressively felt unwell, experiencing tiredness and dreadful joint pain so severe that I am unable to sleep. At first, I did not suspect Praluent, but rather my blood pressure medication. However, my general practitioner ran blood tests and discovered that my liver enzymes were off the scale. Upon reviewing my blood tests over the past five years, it appears that there has been a significant increase in liver enzymes since I began using Praluent. After researching potential side effects, I was horrified to discover that raised liver enzymes were listed. I am now wondering if this medication could be the cause of my health problems and have decided to stop taking it to find out. I am also undergoing tests to examine my gallbladder, which may also be the source of the problem. In addition to the liver enzyme issue, my cholesterol levels have increased over time. I initially started on 75 mg of Praluent every two weeks, which yielded great results in lowering my cholesterol. However, my cholesterol level has now risen to 8.4, indicating that the medication is no longer working. As I researched potential causes of my issues, I was also interested in learning if anyone else had experienced raised liver enzymes as a side effect of Praluent."

• HUG...
• March 6, 2018

"I have been on Praluent for about 18 months. Had some cramping in my hands. Ended up in the hospital last week with cellulitis. The infectious disease doctor said it happened when I gave myself the Praluent shot and it malfunctioned. I am thinking about seeing an attorney as I was in severe pain for several weeks. I am 75 years old."

• Rom...
• Taken for 6 months to 1 year
• March 17, 2024

"I've been taking Praluent 75mg for 9 months. I had experienced serious back pain after the 2nd shot for at least a week. After that, there were no side effects. Most importantly, this drug lowered my blood pressure, so I didn't need to take additional medication I had been on for years! LDL showed 100 less after 2 months on it. Recently, I had to switch to Repatha due to the fact that my insurance no longer supports Praluent. I have plenty of side effects and needed to take blood pressure medication as well. Praluent is way better, even though they are saying it's the same agent."

• Jov...
• Taken for 1 to 6 months
• September 29, 2022

"The injection itself was very painful. After my second injection, I started having memory problems, problems walking, I haven't been able to drive in a week. Became suicidal. Will not take this again. I still have 7-10 days to be out of my system."

• Tur...
• Taken for 1 to 6 months
• January 21, 2021

"My cholesterol was over 300 for over 20 years. Statins made my legs pull and ache, so the doctor decided to try Praluent. After 8 injections, the cardiologist called and told me to stop taking it. My cholesterol was 630 now. Electrolytes nearly doubled. They say this is not a 'normal' reaction, but it is mine. Now they have started me on Repatha. I've taken one injection and am getting blood tested before the 2nd shot. Needless to say, I am nervous."

• Deb...
• Taken for 1 to 2 years
• September 13, 2021

"My numbers were brilliant. But after several months, I suddenly became very ill. I would have episodes of severe dizziness and a feeling of total detachment when all I could do was sit with my head on the table and wait to get back to myself. Or get my husband to guide me to the couch and lay me down. Sometimes the episodes were milder but more frequent, like up to 3 times a day. My consultant was unreachable, so my GP agreed that I should discontinue the Praluent, although he made it clear that he didn't quite believe that the problems were effects of the injections. When the attacks disappeared shortly after I took my last injection, it became obvious that the Praluent was to blame. About 3 months have now gone by, and I still don't feel back to myself. I am left with some lightheadedness, which I hope will wear off."

• Mar...
• Taken for 2 to 5 years
• January 6, 2024

"This stuff rocks! Melted my impossible cholesterol down -200 points after being on maximum statins. I could not get below 300. I’m now bouncing around under 100 every test. I did have to get 3 stents so this does not stop blockages but this is just my body. I have hyperlipidemia and Diabetes at 59."

• ros...
• Taken for 1 to 6 months
• April 12, 2022

"I've had multiple TIA strokes. GP needed to get my bad cholesterol down from 8.6. My family reacts poorly to statins. My cardiologist put me on Praluent, cholesterol is just at a safe level. My dose is 75 mg every two weeks. The only noticeable side effect was calf cramps, which wake me up, treated with magnesium glycinate. The cardiologist wanted me at a lower bad cholesterol. I am now on 150 mg every two weeks. My calf cramps have returned at night, but I have developed a dry cough. My myotherapist said my neck muscles are very tight. Hoping the cough eases off. Used Epsom salt foot bath, this has eased the cramp as I didn't want to take more magnesium by mouth. I'll let you know the outcome of the higher dose after I see the cardiologist. I need to drink much more water to keep my blood pressure normal. Cheers."

• DCa...
• Taken for 1 to 6 months
• August 2, 2021

"I have been taking this drug for around 6 months now, 75 mg, a woman in her early 60s, pretty healthy, and watch my intake of everything. Taking this for high cholesterol, suffering from really bad muscle aches and pains, also terrible night cramping. Experiencing dizzy spells and headaches, also, which I have never suffered from before in my lifetime. Tummy discomfort and palpitations and night sweats. Decided to come off for 6 weeks and felt much better. Took an injection last night and did not feel well at all, palpitations and dizziness straight away. Nope, not for me, quality of life is more important, and what will be will be."

• Bon...
• Taken for 5 to 10 years
• June 27, 2023

"I've been taking Praluent for 5 years and have had no side effects that I could link to Praluent until now. I also have Sjögren's syndrome, which is an autoimmune condition. My liver enzymes have been elevated; my liver doctor diagnosed me with primary biliary cholangitis, but from taking a fibro scan, my liver shows to be completely healthy. The doctor says the autoimmune condition is migrating to another organ, my liver. But after looking at the side effect info on Praluent, I find there is a rare but severe side effect of elevated liver enzymes. The other more common side effect that I have is a cold (I never made the connection to Praluent). I've had a cold since June 2022, an entire year. I've also had a runny nose for 5 years since I began taking Praluent; I'm writing this review because I think anybody on Praluent should have their liver values checked. No symptoms exist, so you'd never know your liver was in trouble. It did bring down my cholesterol."

• Sky...
• Taken for 6 months to 1 year
• July 31, 2021

"A female, 60+, I started Praluent injections (150 mg twice a month) in December 2020. At that time, I had a history of normal blood pressure. After 2 months on Praluent, my LDL dropped to 33, however, I began getting rashes, hip and back pain, my feet felt numb and tingly, and my blood pressure increased. I asked my doctor to reduce the dose to 75 mg twice a month. I have now been on it for almost 8 months, and my blood pressure has steadily increased. I am now on BP medication for hypertension. This drug is outstanding for reducing familial high cholesterol, but in my case, the side effects frighten me. I will stick with a statin."

• DLB...
• Taken for 6 months to 1 year
• January 1, 2024

"I have been using Praluent for 6 months. Previous attempts to lower my cholesterol (normally in the 300-400 range) with statins and supplements were unsuccessful, leading to coronary artery disease and a subsequent 5-graft bypass surgery. After 6 months on Praluent injections (easy to administer with foolproof visual window), new blood work showed my cholesterol at 101, a stunning improvement. I couldn't ask for more. One minor side effect was skin flaking in about a 6-inch radius around the injection site (usually belly). No itching, just flaking. Small price to pay for such a great benefit."