Generic Name: Apremilast (a PRE mi last)
Brand Name: Otezla
Medically reviewed by Drugs.com. Last updated on Jan 25, 2020.
Uses of Apremilast:
- It is used to treat psoriatic arthritis.
- It is used to treat plaque psoriasis.
- It is used to treat oral ulcers caused by Behcet's disease.
What do I need to tell my doctor BEFORE I take Apremilast?
- If you have an allergy to apremilast or any other part of apremilast.
- If you are allergic to apremilast; any part of apremilast; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
- If you are taking any of these drugs: Carbamazepine, phenobarbital, phenytoin, or rifampin.
This is not a list of all drugs or health problems that interact with apremilast.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take apremilast with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Apremilast?
- Tell all of your health care providers that you take apremilast. This includes your doctors, nurses, pharmacists, and dentists.
- This medicine may cause weight loss. You will need to have your weight checked while taking apremilast. Talk with your doctor.
- If you are 65 or older, use apremilast with care. You could have more side effects.
- Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.
How is this medicine (Apremilast) best taken?
Use apremilast as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Take with or without food.
- Swallow whole. Do not chew, break, or crush.
- Keep taking apremilast as you have been told by your doctor or other health care provider, even if you feel well.
What do I do if I miss a dose?
- Take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Very bad diarrhea, upset stomach, and throwing up have happened with apremilast. Sometimes, these problems have led to the need to go to the hospital. Call your doctor right away if you have diarrhea, upset stomach, or throwing up that is very bad, bothers you, or does not go away.
- This medicine may raise the chance of low mood (depression). The risk may be greater in people who have had low mood or thoughts or actions of suicide in the past. Watch people who take apremilast closely. Call the doctor right away if signs like low mood, nervousness, restlessness, grouchiness, panic attacks, or changes in mood or actions are new or worse. Call the doctor right away if any thoughts or actions of suicide occur.
What are some other side effects of Apremilast?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Stomach pain or diarrhea.
- Upset stomach or throwing up.
- Weight loss.
- Signs of a common cold.
- Back pain.
- Joint pain.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Apremilast?
- Store at room temperature.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about apremilast, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about apremilast
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- En Español
- 366 Reviews
- Drug class: antirheumatics
Other brands: Otezla