Oxybutynin Patient Tips
Medically reviewed by C. Fookes, BPharm. Last Updated on Oct 16, 2018.
How it works
- Oxybutynin relaxes smooth muscle in the bladder wall. This increases the urine-holding capacity of the bladder, decreases bladder contractions, and delays the initial desire to empty the bladder. Oxybutynin does this by blocking the release of acetylcholine, a chemical transmitter responsible for muscle contraction within the bladder.
- Oxybutynin belongs to the class of medicines known as anticholinergics (also known as antimuscarinics).
- Oxybutynin decreases both the urgency and frequency of urination.
- Helps with bladder control in people with an overactive bladder, urinary incontinence or with urinary leakage.
- Available as a normal release tablet, an extended-release tablet, an oral solution, a transdermal patch, and a transdermal gel.
- Generic oxybutynin is available.
If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include:
- Dry mouth, constipation, thirst, abdominal pain, nausea, or little or no urination. May also cause blurred vision and affect your ability to drive or operate machinery.
- Seek immediate medical advice if side effects such as hallucinations, agitation, confusion or sleepiness occur, particularly in the first few months of treatment or after a dosage increase.
- Not suitable for people with or at risk of urinary retention, severe decreased gastrointestinal motility conditions, or uncontrolled narrow-angle glaucoma. May also not be recommended for people with heart disease, dementia, liver or kidney disease, an enlarged prostate, myasthenia gravis, inflammatory bowel disorders, GERD or in frail, elderly people.
- Rarely, may cause angioedema (a skin reaction characterized by swelling of the face, lips, tongue or throat). In some cases, this occurred after the first dose. Seek urgent medical help if these symptoms or breathing difficulties occur.
- Can decrease perspiration and increase the risk of developing heat stroke. Avoid overheating or becoming dehydrated in hot weather or during exercise.
- May interact with several other drugs including ketoconazole, itraconazole, and erythromycin.
- May also alter the absorption of other medications taken at the same time due to its effects on gastrointestinal motility.
Notes: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. For a complete list of all side effects, click here.
- Oxybutynin may be taken with or without food. Take with a glass of water.
- Take exactly as directed by your doctor. Do not take more or less than recommended.
- Do not crush, chew, or break an extended-release tablet. Swallow it whole.
- Oxybutynin patches should be applied to dry, intact skin on the abdomen, hip, or buttock, twice weekly (every three to four days). Avoid consecutive reapplication to the same site.
- Seek immediate medical attention if you notice any swelling of your lips, tongue or throat or difficulty breathing.
- Be careful not to become dehydrated during hot weather while taking oxybutynin as heat stroke can occur.
- Be aware that alcohol can enhance the sedative effect of oxybutynin.
- Your vision may become blurred with oxybutynin and affect your ability to drive.
- Seek urgent medical attention if you develop hot and dry skin, extreme thirst, constipation or severe stomach pain; or difficulty, pain, or burning with urination.
Response and Effectiveness
- Peak concentrations are reached within half to one hour. Effects of immediate release oxybutynin tablets are relatively short-lived but may last up to eight hours.
- Immediate-release oxybutynin is usually taken three to four times daily unless it is just used for night-time urinary incontinence when one dose is taken at night. An extended-release tablet (Ditropan XL) and a patch which is placed on the skin (Oxytrol) are also available.
Oxybutynin [Package Insert]. Revised: 09/2018. Tulex Pharmaceuticals, Inc. https://www.drugs.com/pro/oxybutynin.html
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- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use oxybutynin only for the indication prescribed.
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