Univasc Side Effects

Generic name: moexipril

Medically reviewed by Drugs.com. Last updated on Dec 2, 2024.

Note: This document provides detailed information about Univasc Side Effects associated with moexipril. Some dosage forms listed on this page may not apply specifically to the brand name Univasc.

Applies to moexipril: oral tablet.

Precautions

It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly. Blood tests may be needed to check for unwanted effects.

Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using this medicine, tell your doctor right away.

This medicine may cause serious types of allergic reactions. These reactions can be life-threatening and require immediate medical attention. Call your doctor right away if you have a rash, itching, hoarseness, trouble breathing, trouble swallowing, or any swelling of your face, arms, legs, eyes, lips, tongue, or throat while you are using this medicine.

Call your doctor right away if you have severe stomach pain (with or without nausea or vomiting). This could be a symptom of a condition called intestinal angioedema.

Dizziness, lightheadedness, or fainting may also occur, especially when you get up from a lying or sitting position or if you have been taking a diuretic (water pill). Make sure you know how you react to the medicine before you drive, use machines, or do other things that could be dangerous if you are dizzy or not alert. If you feel dizzy, lie down so you do not faint. Then sit for a few moments before standing to prevent the dizziness from returning. If you faint, stop using this medicine and call your doctor right away.

Check with your doctor right away if you become sick while taking this medicine, especially with severe or continuing nausea, vomiting, or diarrhea. These conditions may cause you to lose too much water or salt and may lead to low blood pressure. You can also lose water by sweating, so drink plenty of water during exercise or in hot weather.

Check with your doctor if you have a fever, chills, or sore throat. These may be symptoms of an infection caused by low white blood cells.

Check with your doctor right away if you have any symptoms of liver problems, such as dark-colored urine or pale stools, nausea, vomiting, loss of appetite, pain in your upper stomach, or yellow skin or eyes.

Hyperkalemia (high potassium in the blood) may occur while you are using this medicine. Check with your doctor right away if you have the following symptoms: abdominal or stomach pain, confusion, difficulty breathing, irregular heartbeat, nausea or vomiting, nervousness, numbness or tingling in the hands, feet, or lips, shortness of breath, or weakness or heaviness of the legs. Do not use supplements or salt substitutes containing potassium without first checking with your doctor.

Make sure any doctor or dentist who treats you knows that you are using this medicine. You may need to stop using this medicine several days before having surgery or medical tests.

Black patients may be less sensitive to the blood pressure-lowering effects of this medicine. In addition, the risk of a serious allergic reaction involving swelling of the face, mouth, hands, or feet may be increased.

Do not take other medicines unless they have been discussed with your doctor. This especially includes over-the-counter (nonprescription) medicines for appetite control, asthma, colds, cough, hay fever, or sinus problems, since they may tend to increase your blood pressure.

Common side effects of Univasc

Some side effects of moexipril may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Serious side effects of Univasc

Along with its needed effects, moexipril (the active ingredient contained in Univasc) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking moexipril:

For healthcare professionals

Applies to moexipril: oral tablet.

General adverse events

The most commonly reported adverse effects considered to be related to use of this drug were headache, cough, dizziness, fatigue, flushing, and rash.^[Ref]

Other

• Common (1% to 10%): Fatigue, flu syndrome, pain, peripheral edema, chest pain
• Uncommon (0.1% to 1%): Fever
• Rare (less than 0.1%): Malaise^[Ref]

Respiratory

• Common (1% to 10%): Cough, pharyngitis, upper respiratory tract infection, rhinitis, sinusitis
• Rare (less than 0.1%): Bronchospasm, dyspnea
• Frequency not reported: Eosinophilic pneumonitis^[Ref]

Gastrointestinal

• Common (1% to 10%): Diarrhea, dyspepsia, nausea
• Uncommon (0.1% to 1%): Abdominal pain, constipation, vomiting
• Rare (0.01% to 0.1%): Dry mouth
• Very rare (less than 0.01%): Pancreatitis
• Frequency not reported: Intestinal angioedema^[Ref]

Nervous system

• Common (1% to 10%): Headache, dizziness
• Uncommon (0.1% to 1%): Cerebrovascular accident, transient ischemic attack, syncope
• Rare (less than 0.1%): Numbness, paresthesia, balance disturbance, drowsiness, tingling sensations, alteration or transient loss of taste, tinnitus^[Ref]

Renal

• Common (1% to 10%): Serum creatinine increased, BUN increased
• Rare (less than 0.1%): Acute renal failure, renal insufficiency^[Ref]

Dermatologic

• Common (1% to 10%): Rash
• Uncommon (0.1% to 1%): Stevens-Johnson syndrome, toxic epidermal necrolysis, pruritus, urticaria, erythema multiforme, psoriasis-like efflorescence, pemphigus, alopecia
• Rare (less than 0.1%): Angioedema
• Frequency not reported: Sweating, photosensitivity^[Ref]

Cardiovascular

• Common (1% to 10%): Flushing
• Uncommon (0.1% to 1%): Myocardial infarction, angina pectoris, rhythm disorder, tachycardia, palpitation, hypotension
• Frequency not reported: Symptomatic hypotension, postural hypotension^[Ref]

Musculoskeletal

• Common (1% to 10%): Myalgia
• Uncommon (0.1% to 1%): Arthralgia^[Ref]

Genitourinary

• Common (1% to 10%): Urinary frequency
• Rare (less than 0.1%): Impotence
• Frequency not reported: Oliguria^[Ref]

Metabolic

• Uncommon (0.1% to 1%): Appetite loss, uric acid elevated
• Rare (less than 0.1%): Hyperkalemia
• Frequency not reported: Hyponatremia^[Ref]

Hematologic

• Rare (0.01% to 0.1%): Anemia, neutropenia, eosinophilia, thrombocytopenia
• Very rare (less than 0.01%): Pancytopenia, agranulocytosis, hemolytic anemia in patients with glucose-6-phosphate dehydrogenase deficiency, hemoglobin decreased, hematocrit decreased, platelets decreased, white cell count decreased^[Ref]

Psychiatric

• Rare (less than 0.1%): Confusion, depression, sleep disturbances
• Frequency not reported: Nervousness, mood changes, anxiety^[Ref]

Ocular

• Rare (less than 0.1%): Vision blurred^[Ref]

Hepatic

• Very rare (less than 0.01%): Hepatitis, liver enzymes elevated, serum bilirubin elevated^[Ref]

See also:

Further information

Univasc side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer