Olodaterol Side Effects

Medically reviewed by Drugs.com. Last updated on Oct 28, 2024.

Applies to olodaterol: inhalation spray.

Precautions

It is very important that your doctor check your progress at regular visits to make sure the medicine is working properly. Blood tests may be needed to check for any unwanted effects.

This medicine should not be used together with similar inhaled medicines, such as albuterol (Proventil®, Ventolin®), isoproterenol (Isuprel®), metaproterenol (Alupent®), pirbuterol (Maxair®), or terbutaline (Bricanyl®).

Tell your doctor if you are also using any other medicine for your COPD. Your doctor may want you to use it only during a severe COPD attack. Follow your doctor's instructions on how you should take your medicine.

This medicine should not be used if you are having a severe asthma or COPD attack, or if symptoms of an asthma or COPD attack has already started. Your doctor may prescribe another medicine for you to use in case of an acute COPD attack. If the other medicine does not work as well, tell your doctor right away.

Talk with your doctor or get medical care right away if:

• Your symptoms do not improve after using this medicine or if they become worse.
• Your short-acting inhaler does not seem to work as well as it used to and you need it more often than normal.
• You have a big decrease in your peak flow when measured as directed by your doctor.

This medicine may increase the risk of worsening asthma, which may lead to hospitalization, intubation, and death in patients with asthma who take this medicine without an inhaled steroid medicine. Talk to your doctor if you have concerns about this.

This medicine may cause paradoxical bronchospasm, which means your breathing or wheezing will get worse. Paradoxical bronchospasm may be life-threatening. Check with your doctor right away if you have coughing, difficulty breathing, shortness of breath, or wheezing after using this medicine.

Olodaterol may cause heart or blood vessel problems, including heart rhythm problems. Check with your doctor right away if you have chest pain or tightness, decreased urine output, dilated neck veins, extreme fatigue, irregular heartbeat, swelling of the face, fingers, feet, or lower legs, troubled breathing, or weight gain.

Hypokalemia (low potassium in the blood) may occur while you are using this medicine. Check with your doctor right away if you have more than one of the following symptoms: convulsions (seizures), decreased urine, dry mouth, increased thirst, irregular heartbeat, loss of appetite, mood changes, muscle pain or cramps, nausea or vomiting, numbness or tingling in the hands, feet, or lips, shortness of breath, or unusual tiredness or weakness.

This medicine may affect blood sugar levels. If you are diabetic and notice a change in the results of your blood or urine sugar tests, check with your doctor.

This medicine may cause serious allergic reactions, including angioedema, which can be life-threatening and require immediate medical attention. Check with your doctor right away if you have a rash, itching, a large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals, trouble breathing, or chest tightness while you are using this medicine.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Serious side effects of olodaterol

Along with its needed effects, olodaterol may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking olodaterol:

Get emergency help immediately if any of the following symptoms of overdose occur while taking olodaterol:

Symptoms of overdose

• blurred vision
• chest pain or discomfort
• confusion
• decreased urine
• dizziness
• drowsiness
• dry mouth
• fast, pounding, or irregular heartbeat or pulse
• flushed, dry skin
• fruit-like breath odor
• general feeling of discomfort or illness
• headache
• increased hunger
• increased thirst
• increased urination
• irregular heartbeat
• mood changes
• muscle spasm or tremors
• nausea
• nervousness
• numbness or tingling in the hands, feet, or lips
• pain or discomfort in the arms, jaw, back, or neck
• pounding in the ears
• rapid, deep breathing
• restlessness
• seizures
• slow heartbeat
• stomach cramps
• troubled breathing
• unexplained weight loss
• unusual tiredness or weakness
• vomiting

Other side effects of olodaterol

Some side effects of olodaterol may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For healthcare professionals

Applies to olodaterol: inhalation aerosol.

General adverse events

The most common adverse effect leading to discontinuation was worsening COPD.

The most common serious adverse events were COPD exacerbation, pneumonia, and atrial fibrillation.^[Ref]

Cardiovascular

• Common (1% to 10%): Hypertension^[Ref]

Gastrointestinal

• Common (1% to 10%): Diarrhea, constipation^[Ref]

Genitourinary

• Common (1% to 10%): Urinary tract infection^[Ref]

Musculoskeletal

• Common (1% to 10%): Back pain, arthralgia^[Ref]

Nervous system

• Common (1% to 10%): Dizziness^[Ref]

Respiratory

• Common (1% to 10%): Nasopharyngitis, upper respiratory tract infection, bronchitis, cough, pneumonia^[Ref]

Other

• Common (1% to 10%): Pyrexia^[Ref]

Dermatologic

• Uncommon (0.1% to 1%): Rash^[Ref]

See also:

Further information

Olodaterol side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer