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Olodaterol

Generic Name: olodaterol (OH-loe-DA-ter-ol)
Brand Name: Striverdi Respimat

Long-acting beta-agonists such as olodaterol have been rarely associated with an increased risk of asthma-related death. Olodaterol is not approved for the treatment of asthma; safety and effectiveness in patients with asthma have not been confirmed.


Olodaterol is used for:

Long-term control of chronic obstructive pulmonary disease (COPD) symptoms. It may also be used for other conditions as determined by your doctor.

Olodaterol is a long-acting beta-agonist bronchodilator. It works by widening the airways in the lungs, which helps you breathe more easily.

Do NOT use olodaterol if:

  • you are allergic to any ingredient in olodaterol
  • you are using another medicine that has a long-acting beta-agonist (eg, salmeterol) in it
  • you are having sudden, severe onset or worsening of COPD symptoms (eg, chest tightness, cough, shortness of breath, or wheezing)
  • you have asthma

Contact your doctor or health care provider right away if any of these apply to you.

Before using olodaterol:

Some medical conditions may interact with olodaterol. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of diabetes, heart problems (eg, fast or irregular heartbeat, heart blood vessel problems), high blood pressure, low blood potassium levels, seizures, or an overactive thyroid
  • if you have had an unusual reaction to a sympathomimetic medicine (eg, albuterol, pseudoephedrine), such as fast or irregular heartbeat, overexcitement, or severe trouble sleeping
  • if you are taking linezolid, a monoamine oxidase inhibitor (MAOI) (eg, phenelzine), or a tricyclic antidepressant (eg, amitriptyline) or you have taken any of these medicines within the last 14 days
  • if you take any medicine that may increase the risk of a certain type of irregular heartbeat (prolonged QT interval). Check with your doctor or pharmacist if you are unsure if any of your medicines may increase the risk of this type of irregular heartbeat

Some MEDICINES MAY INTERACT with olodaterol. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Corticosteroids (eg, prednisone), diuretics (eg, furosemide, hydrochlorothiazide), or xanthines (eg, theophylline) because the risk of low blood potassium or irregular heartbeat may be increased
  • Linezolid, other long-acting beta-agonists (eg, salmeterol), MAOIs (eg, phenelzine), or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of olodaterol's side effects
  • Beta-blockers (eg, propranolol) because they may decrease olodaterol's effectiveness or worsen your condition

This may not be a complete list of all interactions that may occur. Ask your health care provider if olodaterol may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use olodaterol:

Use olodaterol as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Olodaterol comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get olodaterol refilled.
  • Olodaterol is for inhalation only. Do not spray into the eyes.
  • Before first using olodaterol, put the cartridge into the inhaler.
  • You will need to prime the inhaler. Point it toward the ground and spray until you see medicine come out. After you see the medicine come out, spray 3 more times. Do this before first using olodaterol and if it is not used for more than 21 days.
  • If olodaterol is not used for more than 3 days, spray once before using.
  • Use the new inhaler that comes with each refill.
  • Have your inhaler use checked with your doctor at each visit. Read and follow facts on how to use the inhaler. Make sure you use the inhaler the right way.
  • Use olodaterol at the same time of day.
  • Use olodaterol on a regular schedule to get the most benefit from it.
  • If you miss a dose of olodaterol, use it as soon as possible. Do not use more often than 1 time every 24 hours.

Ask your health care provider any questions you may have about how to use olodaterol.

Important safety information:

  • Do not stop using olodaterol or other medicines used to control or treat your COPD without checking with your doctor.
  • Olodaterol will not relieve sudden, severe onset or worsening COPD symptoms or other breathing problems once they have already started. Be sure to carry a short-acting bronchodilator inhaler (eg, albuterol) with you at all times to treat any breathing problems that may occur between doses of olodaterol (eg, severe or sudden onset of wheezing or shortness of breath). If you have any questions about which medicines relieve these breathing problems, check with your doctor or pharmacist.
  • If you have been regularly using a short-acting bronchodilator inhaler, talk with your doctor about how to use it with olodaterol. Short-acting bronchodilators are normally used with olodaterol to treat breathing problems that may occur between doses.
  • The risk of serious heart problems (eg, irregular heartbeat) may be greater if you use olodaterol in high doses. Do NOT use more than recommended dose or use more often than prescribed.
  • If your symptoms do not get better or if they get worse, contact your doctor right away.
  • Tell your doctor at once if you notice that your short-acting bronchodilator inhaler does not work as well, if you need to use it often, or if you have a decrease in your peak flow meter results.
  • Contact your doctor or seek medical care right away if you have breathing problems that worsen quickly, or if you use your short-acting bronchodilator and do not get relief.
  • Talk with your doctor or pharmacist about all of your COPD medicines and how to use them. Your doctor may make changes to your COPD control medicines once your COPD is well controlled. Do not start, stop, or change the dose of any COPD medicine unless your doctor tells you to.
  • The medicine may cause severe breathing problems right after you use a dose. If this happens, use your short-acting bronchodilator. Contact your doctor or seek other medical care at once.
  • Olodaterol may raise your blood sugar. High blood sugar may make you feel confused, drowsy, or thirsty. It can also make you flush, breathe faster, or have a fruit-like breath odor. If these symptoms occur, tell your doctor right away.
  • Lab tests may be performed while you use olodaterol. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Olodaterol is not approved for use in CHILDREN. Talk with the doctor.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using olodaterol while you are pregnant. It is not known if this medicine is found in breast milk. If you are or will be breast-feeding while you use olodaterol, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of olodaterol:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Nose or throat irritation.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; fast or irregular heartbeat; muscle pain, weakness, or cramps; new or worsening COPD symptoms (eg, increased chest tightness, coughing, shortness of breath, wheezing) or other breathing problems; nervousness; severe or persistent headache or dizziness; tremor.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of olodaterol:

Store olodaterol at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Do not freeze. Store away from heat, moisture, and light. Do not store in the bathroom. After putting the cartridge in the inhaler, throw it away 3 months after first using or when the inhaler locks up, whichever happens first. Keep olodaterol out of the reach of children and away from pets.

General information:

  • If you have any questions about olodaterol, please talk with your doctor, pharmacist, or other health care provider.
  • Olodaterol is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take olodaterol or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about olodaterol. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to olodaterol. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your health care provider for complete information about the risks and benefits of using olodaterol.

Review Date: August 8, 2016

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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