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Latanoprost ophthalmic Side Effects

For the Consumer

Applies to latanoprost ophthalmic: ophthalmic solution

Along with its needed effects, latanoprost ophthalmic may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking latanoprost ophthalmic:

Less Common

  • Eyelid crusting, redness, swelling, discomfort, or pain

Rare

  • Cough
  • difficulty breathing
  • noisy breathing
  • redness of eye or inside of eyelid
  • shortness of breath
  • swelling of the eye
  • tightness in chest
  • wheezing

Check with your doctor as soon as possible if any of the following side effects occur while taking latanoprost ophthalmic:

More Common

  • Blurred vision, eye irritation, or tearing
  • darkening of eyelid skin color
  • increase in brown color in colored part of eye
  • longer, thicker, and darker eyelashes

Less Common

Rare

  • Discharge from the eye
  • double vision or other change in vision
  • fever
  • sensitivity of eye to light
  • sore throat

Some side effects of latanoprost ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More Common

  • Burning of eye
  • feeling of something in eye
  • itching of eye
  • stinging of eye

Less Common

  • Dryness of eye

For Healthcare Professionals

Applies to latanoprost ophthalmic: ophthalmic solution

Ocular

Very common (10% or more): Iris pigmentation (33%), foreign body sensation (13%), punctate epithelial keratopathy (10%), eye irritation

Common (1% to 10%): Stinging, conjunctival hyperemia, blurred vision, itching, burning, increased pigmentation of the iris, excessive tearing, lid discomfort/pain, dry eye, eye pain, lid crusting, lid erythema, photophobia, lid edema, blepharitis

Uncommon (0.1% to 1%): Keratitis

Rare(less than 0.1%): Distichiasis

Postmarketing reports: Eyelash/vellus hair changes (increased length, thickness, pigmentation, and number), corneal edema/erosions, intraocular inflammation (iritis/uveitis), macular edema (including cystoid macular edema), misdirected eyelashes, periorbital and lid changes resulting in deepening of the eyelid sulcus[Ref]

Respiratory

Common (1% to 10%): Upper respiratory tract infection/cold/flu, bronchitis

Very are (less than 0.01%): Asthma and exacerbation of asthma, dyspnea[Ref]

Musculoskeletal

Common (1% to 10%): Muscle/joint/back pain

Postmarketing reports: Myalgia, arthralgia[Ref]

Cardiovascular

Very rare (less than 0.01%): Aggravation of angina in patients with pre-existing disease, chest pain

Postmarketing reports: Palpitations[Ref]

Dermatologic

Common (1% to 10%): Rash, allergic skin reaction

Postmarketing reports: Toxic epidermal necrolysis, eyelid skin darkening[Ref]

Nervous system

Postmarketing reports: Dizziness, headache[Ref]

General

The most commonly reported side effect was increased iris pigmentation.[Ref]

Genitourinary

Common (1% to 10%): Urinary tract infection[Ref]

Hepatic

Common (1% to 10%): Abnormal liver function[Ref]

Immunologic

Postmarketing reports: Herpes keratitis[Ref]

References

1. "Product Information. Xalatan (latanoprost ophthalmic)." Pharmacia and Upjohn, Kalamazoo, MI.

2. Cerner Multum, Inc. "Australian Product Information." O 0

3. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

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