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What is the difference between Xelpros and Xalatan?

Medically reviewed by Last updated on Oct 5, 2020.

Official answer


Xelpros does not contain the preservative benzalkonium chloride. Xalatan does contain benzalkonium chloride.

Xelpros (latanoprost ophthalmic emulsion) 0.005% from Sun Pharma is the first formulation of latanoprost that does not contain the common preservative benzalkonium chloride (BAK). Xelpros is a prostaglandin analogue used to reduce elevated intraocular (inside the eye) pressure in patients with open-angle glaucoma or ocular hypertension. Research has shown eye drops containing BAK can cause allergic reactions, dry eye, eye redness, and other adverse reactions in some patients. In addition, BAK can be absorbed by contact lenses.

Xalatan, also a latanoprost 0.005% eye drop from Pfizer, does contain the preservative BAK. However, even though Xelpros does not contain BAK, both manufacturers recommend that you remove your contact lenses prior to the instillation of either Xelpros or Xalatan eye drops. Your contact lenses may be reinserted 15 minutes after use of the drop.

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