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Giltuss Honey DM 8hr Cough Side Effects

Generic name: dextromethorphan

Medically reviewed by Last updated on Jun 14, 2023.

Note: This document contains side effect information about dextromethorphan. Some dosage forms listed on this page may not apply to the brand name Giltuss Honey DM 8hr Cough.

Applies to dextromethorphan: mouth/throat lozenge, oral capsule, oral gel, oral liquid, oral strip, oral suspension extended release, oral syrup, oral tablet chewable.

Serious side effects

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.

Other side effects

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if you have any side effects that bother you or do not go away.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at

For Healthcare Professionals

Applies to dextromethorphan: compounding powder, oral capsule, oral disintegrating strip, oral drops, oral liquid, oral lozenge, oral solution, oral suspension extended release, oral syrup, oral tablet chewable.


Adverse effects have included gastrointestinal disturbances such as stomach upset and diarrhea.[Ref]

Nervous system

Frequency not reported: Drowsiness, dizziness, convulsions[Ref]


Frequency not reported: Respiratory depression[Ref]


Frequency not reported: Vomiting, nausea, diarrhea, abdominal pain, gastrointestinal disturbance[Ref]


Rare (less than 0.1%): Fixed-drug eruptions[Ref]


Cases of abuse have been reported.[Ref]

Frequency not reported: Mental confusion, excitation, insomnia, abuse[Ref]


Frequency not reported: Rash, angioedema, pruritus, urticaria[Ref]

Frequently asked questions

More about Giltuss Honey DM 8hr Cough (dextromethorphan)

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1. Cerner Multum, Inc. UK Summary of Product Characteristics.

2. Hall RC, Beresford TP, Stickney SK, Nasdahl CS, Coleman JH. Psychiatric reactions produced by respiratory drugs. Psychosomatics. 1985;26:605-8,616-7.

3. Helfer J, Kim OM. Psychoactive abuse potential of Robitussin-DM. Am J Psychiatry. 1990;147:672-3.

4. Murray S, Brewerton T. Abuse of over-the-counter dextromethorphan by teenagers. South Med J. 1993;86:1151-3.

5. Wolfe TR, Caravati EM. Massive dextromethorphan ingestion and abuse. Am J Emerg Med. 1995;13:174-6.

6. Polles A, Griffith JL. Dextromethorphan-induced mania. Psychosomatics. 1996;37:71-4.

7. Bostwick JM. Dextromethorphan-induced manic symptoms in a bipolar patient on lithium. Psychosomatics. 1996;37:571-2.

8. Stubb S, Reitamo S. Fixed-drug eruption due to dextromethorphan . Arch Dermatol. 1990;126:970-1.

9. Knowles SR, Weber E. Dextromethorphan anaphylaxis. J Allerg Clin Immunol. 1998;102:316-7.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.